DK391289D0 - Indolderivater - Google Patents

Indolderivater

Info

Publication number
DK391289D0
DK391289D0 DK391289A DK391289A DK391289D0 DK 391289 D0 DK391289 D0 DK 391289D0 DK 391289 A DK391289 A DK 391289A DK 391289 A DK391289 A DK 391289A DK 391289 D0 DK391289 D0 DK 391289D0
Authority
DK
Denmark
Prior art keywords
alkyl
compounds
disclosed
indole derivatives
headache
Prior art date
Application number
DK391289A
Other languages
English (en)
Other versions
DK391289A (da
Inventor
Ian Harold Coates
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DK391289D0 publication Critical patent/DK391289D0/da
Publication of DK391289A publication Critical patent/DK391289A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
DK391289A 1988-08-10 1989-08-09 Indolderivater DK391289A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819024A GB8819024D0 (en) 1988-08-10 1988-08-10 Chemical compounds

Publications (2)

Publication Number Publication Date
DK391289D0 true DK391289D0 (da) 1989-08-09
DK391289A DK391289A (da) 1990-02-11

Family

ID=10641919

Family Applications (1)

Application Number Title Priority Date Filing Date
DK391289A DK391289A (da) 1988-08-10 1989-08-09 Indolderivater

Country Status (13)

Country Link
US (1) US5036078A (da)
EP (1) EP0354777B1 (da)
JP (1) JP2941309B2 (da)
KR (1) KR900003151A (da)
AT (1) ATE92485T1 (da)
AU (1) AU3945589A (da)
DE (1) DE68908040T2 (da)
DK (1) DK391289A (da)
FI (1) FI893751A (da)
GB (1) GB8819024D0 (da)
NO (1) NO893205L (da)
PT (1) PT91417B (da)
ZA (1) ZA896067B (da)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI92397C (fi) * 1987-08-13 1994-11-10 Glaxo Group Ltd Menetelmä valmistaa farmaseuttisesti käyttökelpoisia indolijohdoksia
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
CZ288351B6 (en) * 1990-06-07 2001-05-16 Astrazeneca Ab Nitrogenous heterocyclic compound, process of its preparation and use as well as a medicament containing thereof
DK152090D0 (da) * 1990-06-22 1990-06-22 Lundbaek A S H Piperidylsubstituerede indolderivater
BR9106978A (pt) * 1990-10-15 1993-09-28 Pfizer Derivados de indol
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
CA2124206C (en) * 1991-11-25 2001-02-27 John Eugene Macor Indole derivatives
TW288010B (da) * 1992-03-05 1996-10-11 Pfizer
US5747501A (en) 1992-04-07 1998-05-05 Pfizer, Inc. Indole derivatives
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
BR9306221A (pt) * 1992-04-10 1998-06-30 Pfizer Derivados do acilaminoindol como agonistas 5-htl
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (da) * 1992-11-02 1995-07-11 Pfizer
JPH06162097A (ja) * 1992-11-16 1994-06-10 Mitsutoyo Corp データベースの検索条件設定方式
GB9320115D0 (en) * 1993-09-29 1993-11-17 Glaxo Group Ltd Process
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
AU702322B2 (en) * 1995-03-20 1999-02-18 Eli Lilly And Company 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles: new 5-ht1f agonists
GB9523583D0 (en) * 1995-11-17 1996-01-17 Merck Sharp & Dohme Therapeutic agents
GB9706089D0 (en) * 1997-03-24 1997-05-14 Scherer Ltd R P Pharmaceutical composition
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
ATE444965T1 (de) 2002-06-21 2009-10-15 Suven Life Sciences Ltd Sich als therapeutische mittel eignende arylalkylindole mit affinität für den serotoninrezeptor, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese enthalten
MXPA04012832A (es) 2002-06-21 2005-05-27 Suven Life Sciences Ltd Arilsulfonil indoles novedosos que tienen afinidad por el receptor de la serotonina, utiles como agentes terapeuticos, proceso para su preparacion y composiciones farmaceuticas que los contienen.
ATE401307T1 (de) 2002-11-28 2008-08-15 Suven Life Sciences Ltd N-arylsulfonyl-2-substituierte indole mit affinität zum serotonin rezeptor, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
AU2003285759B2 (en) 2002-11-28 2010-01-28 Suven Life Sciences Limited N-arylsulfonyl-3-aminoalkoxyindoles
EP1581538B1 (en) 2002-12-18 2007-02-28 Suven Life Sciences Limited Tetracyclic 3-substituted indoles having serotonin receptor affinity
US20050282879A1 (en) * 2004-06-17 2005-12-22 Foad Salehani Methods and composition for treatment of migraine and symptoms thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2421899A1 (fr) * 1978-01-16 1979-11-02 Roussel Uclaf Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
DE3419935A1 (de) * 1984-05-28 1985-11-28 Merck Patent Gmbh, 6100 Darmstadt Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks
DE3430284A1 (de) * 1984-08-17 1986-02-27 Troponwerke GmbH & Co KG, 5000 Köln Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
FI92397C (fi) * 1987-08-13 1994-11-10 Glaxo Group Ltd Menetelmä valmistaa farmaseuttisesti käyttökelpoisia indolijohdoksia

Also Published As

Publication number Publication date
KR900003151A (ko) 1990-03-23
FI893751A (fi) 1990-02-11
NO893205D0 (no) 1989-08-09
PT91417B (pt) 1995-05-04
JP2941309B2 (ja) 1999-08-25
GB8819024D0 (en) 1988-09-14
DK391289A (da) 1990-02-11
PT91417A (pt) 1990-03-08
US5036078A (en) 1991-07-30
NO893205L (no) 1990-02-12
DE68908040D1 (de) 1993-09-09
EP0354777B1 (en) 1993-08-04
JPH0291068A (ja) 1990-03-30
AU3945589A (en) 1990-02-15
EP0354777A3 (en) 1991-04-10
DE68908040T2 (de) 1993-11-18
ZA896067B (en) 1990-06-27
EP0354777A2 (en) 1990-02-14
ATE92485T1 (de) 1993-08-15
FI893751A0 (fi) 1989-08-09

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment