DE68908040D1 - 3-(4-piperidin)-5-(2-sulphonylaminoethyl)-indol-derivate. - Google Patents

3-(4-piperidin)-5-(2-sulphonylaminoethyl)-indol-derivate.

Info

Publication number
DE68908040D1
DE68908040D1 DE8989308083T DE68908040T DE68908040D1 DE 68908040 D1 DE68908040 D1 DE 68908040D1 DE 8989308083 T DE8989308083 T DE 8989308083T DE 68908040 T DE68908040 T DE 68908040T DE 68908040 D1 DE68908040 D1 DE 68908040D1
Authority
DE
Germany
Prior art keywords
alkyl
sulphonylaminoethyl
piperidine
compounds
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989308083T
Other languages
English (en)
Other versions
DE68908040T2 (de
Inventor
Ian Harold Coates
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE68908040D1 publication Critical patent/DE68908040D1/de
Publication of DE68908040T2 publication Critical patent/DE68908040T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
DE89308083T 1988-08-10 1989-08-09 3-(4-Piperidin)-5-(2-sulphonylaminoethyl)-indol-Derivate. Expired - Lifetime DE68908040T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888819024A GB8819024D0 (en) 1988-08-10 1988-08-10 Chemical compounds

Publications (2)

Publication Number Publication Date
DE68908040D1 true DE68908040D1 (de) 1993-09-09
DE68908040T2 DE68908040T2 (de) 1993-11-18

Family

ID=10641919

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89308083T Expired - Lifetime DE68908040T2 (de) 1988-08-10 1989-08-09 3-(4-Piperidin)-5-(2-sulphonylaminoethyl)-indol-Derivate.

Country Status (13)

Country Link
US (1) US5036078A (de)
EP (1) EP0354777B1 (de)
JP (1) JP2941309B2 (de)
KR (1) KR900003151A (de)
AT (1) ATE92485T1 (de)
AU (1) AU3945589A (de)
DE (1) DE68908040T2 (de)
DK (1) DK391289A (de)
FI (1) FI893751A (de)
GB (1) GB8819024D0 (de)
NO (1) NO893205L (de)
PT (1) PT91417B (de)
ZA (1) ZA896067B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT88255B (pt) * 1987-08-13 1995-03-01 Glaxo Group Ltd Processo para a preparacao de derivados do indole
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
MC2210A1 (fr) * 1990-06-07 1992-11-26 Wellcome Found Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
DK152090D0 (da) * 1990-06-22 1990-06-22 Lundbaek A S H Piperidylsubstituerede indolderivater
AU651637B2 (en) * 1990-10-15 1994-07-28 Pfizer Inc. Indole derivatives
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
NZ243065A (en) 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
ES2143992T3 (es) * 1991-11-25 2000-06-01 Pfizer Derivados de 5-(hetero- o carbociclilamino)-indol, su preparacion y uso como 5-ht1 agonistas.
TW288010B (de) * 1992-03-05 1996-10-11 Pfizer
CA2133413C (en) 1992-04-07 2001-04-10 John Eugene Macor Indole derivatives as 5-ht1 antagonists
US6380233B1 (en) 1992-04-07 2002-04-30 Pfizer Inc Indole derivatives as 5-HT1 agonists
GB9207930D0 (en) * 1992-04-10 1992-05-27 Pfizer Ltd Indoles
JP2544704B2 (ja) * 1992-04-10 1996-10-16 フアイザー・インコーポレイテツド ５−ｈｔ▲下１▼アゴニストとしてのアシルアミノインド―ル誘導体
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
TW251284B (de) * 1992-11-02 1995-07-11 Pfizer
JPH06162097A (ja) * 1992-11-16 1994-06-10 Mitsutoyo Corp データベースの検索条件設定方式
GB9320115D0 (en) * 1993-09-29 1993-11-17 Glaxo Group Ltd Process
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
CN1184425A (zh) * 1995-03-20 1998-06-10 伊莱利利公司 5－取代－3－(1,2,3,6－四氢吡啶－4－基)－和3－(哌啶－4－基)－1h－吲哚:新型5－ht1f激动剂
GB9523583D0 (en) * 1995-11-17 1996-01-17 Merck Sharp & Dohme Therapeutic agents
GB9706089D0 (en) * 1997-03-24 1997-05-14 Scherer Ltd R P Pharmaceutical composition
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
EP1537113B9 (de) 2002-06-21 2010-05-26 Suven Life Sciences Limited Sich als therapeutische mittel eignende arylalkylindole mit affinität für den serotoninrezeptor, verfahren zu deren herstellung und pharmazeutische zusammensetzungen, die diese enthalten
DK1523486T3 (da) 2002-06-21 2008-03-03 Suven Life Sciences Ltd Tetracykliske arylsulfonylindoler med serotoninreceptor-affinitet
ES2425143T3 (es) 2002-11-28 2013-10-11 Suven Life Sciences Limited N-Arilsulfonil-3-aminoalcoxiindoles
KR100818508B1 (ko) 2002-11-28 2008-03-31 수벤 라이프 사이언시스 리미티드 세로토닌 수용체 친화력을 가지는 엔-아릴술포닐-3-치환인돌, 그 제조방법 및 그를 포함하는 약제학적 조성물
KR100739987B1 (ko) 2002-12-18 2007-07-16 수벤 라이프 사이언시스 리미티드 세로토닌 수용체 친화력을 가지는 테트라사이클릭 3-치환인돌
US20050282879A1 (en) * 2004-06-17 2005-12-22 Foad Salehani Methods and composition for treatment of migraine and symptoms thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2362628A1 (fr) * 1976-08-26 1978-03-24 Roussel Uclaf Nouveaux derives du piperidyl-indole et leurs sels, procede de preparation et application a titre de medicaments
FR2421899A1 (fr) * 1978-01-16 1979-11-02 Roussel Uclaf Nouveaux derives du tetrahydropyridinyl-indole et leurs sels, le procede de preparation et l'application a titre de medicaments de ces nouveaux produits
ZW19381A1 (en) * 1980-08-12 1983-03-09 Glaxo Group Ltd Heterocyclic compounds
FR2533924A1 (fr) * 1982-10-05 1984-04-06 Roussel Uclaf Nouveaux derives du 4-(1h-indol-3-yl)a-methyl piperidine-1-ethanol, leurs sels, le procede de preparation, l'application a titre de medicaments et les compositions les renfermant
DE3419935A1 (de) * 1984-05-28 1985-11-28 Merck Patent Gmbh, 6100 Darmstadt Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks
DE3430284A1 (de) * 1984-08-17 1986-02-27 Troponwerke GmbH & Co KG, 5000 Köln Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung
US4548939A (en) * 1984-10-01 1985-10-22 Janssen Pharmaceutica N. V. 1H-Indol-3-yl containing 1,3-dimethyl-1H-purine-2,6-diones
IE58370B1 (en) * 1985-04-10 1993-09-08 Lundbeck & Co As H Indole derivatives
GB8600398D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
GB8600397D0 (en) * 1986-01-08 1986-02-12 Glaxo Group Ltd Chemical compounds
PT88255B (pt) * 1987-08-13 1995-03-01 Glaxo Group Ltd Processo para a preparacao de derivados do indole

Also Published As

Publication number Publication date
DK391289A (da) 1990-02-11
DE68908040T2 (de) 1993-11-18
NO893205D0 (no) 1989-08-09
GB8819024D0 (en) 1988-09-14
EP0354777A2 (de) 1990-02-14
PT91417A (pt) 1990-03-08
KR900003151A (ko) 1990-03-23
FI893751A0 (fi) 1989-08-09
PT91417B (pt) 1995-05-04
FI893751A (fi) 1990-02-11
EP0354777A3 (de) 1991-04-10
NO893205L (no) 1990-02-12
JPH0291068A (ja) 1990-03-30
DK391289D0 (da) 1989-08-09
ATE92485T1 (de) 1993-08-15
EP0354777B1 (de) 1993-08-04
AU3945589A (en) 1990-02-15
US5036078A (en) 1991-07-30
JP2941309B2 (ja) 1999-08-25
ZA896067B (en) 1990-06-27

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee