MX359884B - Derivado del acido hialuronico con aminoacido y grupo esterilo introducido en este. - Google Patents

Derivado del acido hialuronico con aminoacido y grupo esterilo introducido en este.

Info

Publication number
MX359884B
MX359884B MX2015002847A MX2015002847A MX359884B MX 359884 B MX359884 B MX 359884B MX 2015002847 A MX2015002847 A MX 2015002847A MX 2015002847 A MX2015002847 A MX 2015002847A MX 359884 B MX359884 B MX 359884B
Authority
MX
Mexico
Prior art keywords
hyaluronic acid
acid derivative
group introduced
amino acid
introduced thereinto
Prior art date
Application number
MX2015002847A
Other languages
English (en)
Other versions
MX2015002847A (es
Inventor
Takashi Nakai
Tomoko Yasugi
Yoshihiro Tampo
Kenji Yasugi
Tsuyoshi Shimoboji
Original Assignee
Chugai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chugai Pharmaceutical Co Ltd filed Critical Chugai Pharmaceutical Co Ltd
Publication of MX2015002847A publication Critical patent/MX2015002847A/es
Publication of MX359884B publication Critical patent/MX359884B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invención se refiere a un derivado de ácido hialurónico que contiene una unidad de disacárido representada por la fórmula (I) o la fórmula (I) y (II) y un complejo que contiene el derivado del ácido hialurónico y un fármaco.
MX2015002847A 2012-09-05 2013-09-05 Derivado del acido hialuronico con aminoacido y grupo esterilo introducido en este. MX359884B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2012195528 2012-09-05
PCT/JP2013/073995 WO2014038641A1 (ja) 2012-09-05 2013-09-05 アミノ酸およびステリル基が導入されたヒアルロン酸誘導体

Publications (2)

Publication Number Publication Date
MX2015002847A MX2015002847A (es) 2015-05-15
MX359884B true MX359884B (es) 2018-10-15

Family

ID=50237247

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015002847A MX359884B (es) 2012-09-05 2013-09-05 Derivado del acido hialuronico con aminoacido y grupo esterilo introducido en este.

Country Status (11)

Country Link
US (1) US11564971B2 (es)
EP (1) EP2894173B1 (es)
JP (1) JP6275044B2 (es)
KR (1) KR102130864B1 (es)
CN (1) CN104603156B (es)
BR (1) BR112015004501B1 (es)
CA (1) CA2884142C (es)
HK (1) HK1205525A1 (es)
MX (1) MX359884B (es)
RU (1) RU2674003C2 (es)
WO (1) WO2014038641A1 (es)

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WO2015044455A1 (en) * 2013-09-30 2015-04-02 Galderma S.A. Single-step functionalization and cross-linking of hyaluronic acid
US20180086852A1 (en) * 2015-03-31 2018-03-29 Kewpie Corporation Hyaluronic Acid Derivative and Manufacturing Method Therefor and Cosmetics, Food Composition, and Pharmaceutical Composition Containing Hyaluronic Acid Derivative
WO2017195880A1 (ja) * 2016-05-11 2017-11-16 中外製薬株式会社 カチオン性基および疎水性基が導入されたヒアルロン酸誘導体
CN108069867A (zh) * 2016-11-17 2018-05-25 常州百凯生物科技有限公司 一种l-丙氨酰胺盐酸盐的制备方法
IT201700122135A1 (it) * 2017-10-26 2019-04-26 Jointherapeutics S R L Acido ialuronico funzionalizzato o suo derivato nel trattamento di stati infiammatori
JP7221211B2 (ja) * 2017-11-15 2023-02-13 中外製薬株式会社 ポリエチレングリコールにより修飾されたヒアルロン酸誘導体
IT201800003841A1 (it) * 2018-03-21 2019-09-21 Acme Drugs S R L Coniugati di stanozololo e acido ialuronico
CN113329764A (zh) * 2019-01-29 2021-08-31 国立大学法人三重大学 癌疫苗制剂
KR20220005465A (ko) * 2019-04-19 2022-01-13 조인테라퓨틱스 에스알엘 작용화된 히알루론산의 가교결합 중합체 및 염증 상태의 치료에서의 이의 용도
EP3976019A4 (en) * 2019-06-03 2023-03-01 Aihol Corporation HYALURONAN CONJUGATES AND USES THEREOF
JP7502861B2 (ja) 2019-12-27 2024-06-19 旭化成株式会社 標的物質と両親媒性高分子との複合体の形成反応の反応温度の評価方法
TWI834948B (zh) * 2020-02-05 2024-03-11 日商旭化成股份有限公司 玻尿酸衍生物組合物、醫藥組合物及玻尿酸衍生物－藥物結合體組合物
US20230066990A1 (en) * 2020-02-07 2023-03-02 Asahi Kasei Kabushiki Kaisha Hyaluronic acid derivative, pharmaceutical composition, and hyaluronic acid derivative-drug complex
KR20210102602A (ko) 2020-02-12 2021-08-20 (주)아모레퍼시픽 생체 활성 물질을 안정화하는 히알루론산 하이드로겔 및 이의 제조 방법
JP2023533679A (ja) * 2020-07-15 2023-08-04 コヴァル バイオファーマ （シャンハイ） カンパニー，リミテッド 治療剤を局所的に送達するための薬物送達システムおよびその使用
EP4349366A1 (en) 2021-05-31 2024-04-10 Mie University Pharmaceutical composition
CN114931563A (zh) * 2022-03-17 2022-08-23 吉林大学 一种透明质酸纳米颗粒/维替泊芬复合物的制备方法
CN115466339A (zh) * 2022-05-13 2022-12-13 宁波格鲁康生物科技有限公司 生物安全注射用改性透明质酸、制备方法及其在美容注射材料上的应用
CN115850534B (zh) * 2022-12-16 2024-03-12 浙江大学 一种透明质酸-胆酸衍生物及其合成方法和应用
CN116763725B (zh) * 2023-08-16 2023-11-24 四川大学华西医院 一种智能响应型可注射水凝胶及其制备方法和应用

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Also Published As

Publication number Publication date
RU2015112219A (ru) 2016-10-27
CN104603156B (zh) 2016-10-26
BR112015004501A2 (pt) 2017-07-04
HK1205525A1 (en) 2015-12-18
EP2894173A1 (en) 2015-07-15
MX2015002847A (es) 2015-05-15
JP6275044B2 (ja) 2018-02-07
RU2674003C2 (ru) 2018-12-04
US11564971B2 (en) 2023-01-31
CN104603156A (zh) 2015-05-06
BR112015004501B1 (pt) 2021-04-13
EP2894173A4 (en) 2016-05-25
CA2884142C (en) 2020-11-10
CA2884142A1 (en) 2014-03-13
JPWO2014038641A1 (ja) 2016-08-12
US20150231268A1 (en) 2015-08-20
WO2014038641A1 (ja) 2014-03-13
EP2894173B1 (en) 2017-04-19
KR20150048238A (ko) 2015-05-06
KR102130864B1 (ko) 2020-07-08

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