MX2014002378A - Proceso para la preparacion de (r)-2-acetamido-n-bencil-3-metoxipr opionamida e intermediarios de la misma. - Google Patents
Proceso para la preparacion de (r)-2-acetamido-n-bencil-3-metoxipr opionamida e intermediarios de la misma.Info
- Publication number
- MX2014002378A MX2014002378A MX2014002378A MX2014002378A MX2014002378A MX 2014002378 A MX2014002378 A MX 2014002378A MX 2014002378 A MX2014002378 A MX 2014002378A MX 2014002378 A MX2014002378 A MX 2014002378A MX 2014002378 A MX2014002378 A MX 2014002378A
- Authority
- MX
- Mexico
- Prior art keywords
- methoxypropionamide
- acetamido
- intermediates
- benzyl
- processes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
Abstract
Esta invención se refiere a procesos para la preparación (R)-2-acetamido-N-bencil-2-metoxipropionamida (I) e intermedios del mismo. (Ver Fórmula).
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161528605P | 2011-08-29 | 2011-08-29 | |
PCT/IB2012/001667 WO2013030654A1 (en) | 2011-08-29 | 2012-08-29 | Processes for the preparation of (r)-2-acetamido-n-benzyl-3-methoxypropionamide and intermediates thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014002378A true MX2014002378A (es) | 2014-06-05 |
MX337610B MX337610B (es) | 2016-03-10 |
Family
ID=47003150
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014002378A MX337610B (es) | 2011-08-29 | 2012-08-29 | Proceso para la preparacion de (r)-2-acetamido-n-bencil-3-metoxipr opionamida e intermediarios de la misma. |
Country Status (4)
Country | Link |
---|---|
US (1) | US9133101B2 (es) |
CA (1) | CA2847285C (es) |
MX (1) | MX337610B (es) |
WO (1) | WO2013030654A1 (es) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9284263B1 (en) * | 2015-03-12 | 2016-03-15 | Satyendra Kumar Pandey | Process for the preparation of(R)-Lacosamide |
WO2018159028A1 (ja) * | 2017-03-01 | 2018-09-07 | 株式会社エーピーアイ コーポレーション | N-ベンジル-2-ブロモ-3-メトキシプロピオン酸アミド及びその中間体の製造方法 |
CN114524746B (zh) * | 2022-01-21 | 2022-11-11 | 河北广祥制药有限公司 | 拉考沙胺晶型的制备方法 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5773475A (en) | 1997-03-17 | 1998-06-30 | Research Corporation Technologies, Inc. | Anticonvulsant enantiomeric amino acid derivatives |
US6048899A (en) * | 1997-03-17 | 2000-04-11 | Research Corporation Tech., Inc. | Anticonvulsant enantiomeric amino acid derivatives |
EP1642889A1 (en) * | 2004-10-02 | 2006-04-05 | Schwarz Pharma Ag | Improved synthesis scheme for lacosamide |
AU2006330638B2 (en) * | 2005-12-20 | 2012-05-31 | Nps Pharmaceuticals, Inc. | Fluorinated compounds |
US8093426B2 (en) * | 2007-12-04 | 2012-01-10 | Ranbaxy Laboratories Limited | Intermediate compounds and their use in preparation of lacosamide |
US20090298947A1 (en) | 2008-05-28 | 2009-12-03 | Pliva Hrvatska D.O.O. | Polymorphic and amorphous forms of lacosamide and amorphous compositions |
JP2010037206A (ja) * | 2008-07-31 | 2010-02-18 | Kaneka Corp | 光学活性なo−メチルセリンまたはその塩の製造法 |
CN101591300B (zh) | 2009-02-19 | 2011-05-04 | 成都伊诺达博医药科技有限公司 | 合成拉考沙胺的新方法 |
EP2480524A1 (en) | 2009-09-25 | 2012-08-01 | Cadila Healthcare Limited | Processes for the preparation of lacosamide and intermediates thereof |
IT1398044B1 (it) | 2010-01-29 | 2013-02-07 | Archimica Srl | Processo per la preparazione della lacosamide |
US8853453B2 (en) | 2010-01-29 | 2014-10-07 | Ranbaxy Laboratories Limited | Processes for reducing impurities in lacosamide |
CN102146048B (zh) | 2010-02-06 | 2013-11-13 | 浙江九洲药业股份有限公司 | 拉科酰胺中间体化合物及其制备方法和应用 |
CA2788451A1 (en) | 2010-02-08 | 2011-08-11 | Natco Pharma Limited | A process for the preparation of lacosamide |
WO2011099033A1 (en) | 2010-02-09 | 2011-08-18 | Msn Laboratories Limited | Process for preparing (r)-2-acetamido-n-benzyl-3-methoxy-propionamide |
US20130123537A1 (en) * | 2010-05-17 | 2013-05-16 | K a s s Narayan Garimella | Process for the preparation of lacosamide |
-
2012
- 2012-08-29 MX MX2014002378A patent/MX337610B/es active IP Right Grant
- 2012-08-29 CA CA2847285A patent/CA2847285C/en active Active
- 2012-08-29 US US14/342,285 patent/US9133101B2/en active Active
- 2012-08-29 WO PCT/IB2012/001667 patent/WO2013030654A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2013030654A1 (en) | 2013-03-07 |
CA2847285C (en) | 2019-10-01 |
US9133101B2 (en) | 2015-09-15 |
WO2013030654A8 (en) | 2013-06-13 |
US20150025274A1 (en) | 2015-01-22 |
CA2847285A1 (en) | 2013-03-07 |
MX337610B (es) | 2016-03-10 |
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