MX353874B - Gotas para los ojos que contienen diquafosol. - Google Patents
Gotas para los ojos que contienen diquafosol.Info
- Publication number
- MX353874B MX353874B MX2014011468A MX2014011468A MX353874B MX 353874 B MX353874 B MX 353874B MX 2014011468 A MX2014011468 A MX 2014011468A MX 2014011468 A MX2014011468 A MX 2014011468A MX 353874 B MX353874 B MX 353874B
- Authority
- MX
- Mexico
- Prior art keywords
- eye drop
- diquafosol
- production
- during
- chelating agent
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7084—Compounds having two nucleosides or nucleotides, e.g. nicotinamide-adenine dinucleotide, flavine-adenine dinucleotide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/04—Artificial tears; Irrigation solutions
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Ophthalmology & Optometry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
En una gota para ojos con Diquafosol que contiene un agente quelante a una concentración de 0.0001 hasta 1% (p/v), la producción de precipitados insolubles durante el almacenamiento, lo cual por lo general se observa en una gota para ojos con Diquafosol, y se puede evitar el deterioro en el desempeño de filtrado durante un proceso de producción (un proceso de esterilización por filtro). En una gota para ojos con Diquafosol que contiene un agente quelante, se observan la reducción en la irritación ocular y la mejora en la eficacia de conservación en comparación con aquellas en una gota para ojos con Diquafosol que no contienen ningún agente quelante. Por lo tanto, en la presente invención, se pueden alcanzar propiedades fisicoquímicas estables durante el curso de producción y distribución y durante el curso de almacenamiento por un paciente, y se observan la reducción en la irritación ocular y la mejora en la eficacia de conservación. En particular, en una gota para ojos con Diquafosol que contiene un agente quelante, se evita el deterioro en el desempeño de filtrado durante un proceso de producción (un proceso de esterilización por filtro). Por lo tanto, se puede alcanzar una esterilización por filtro bastante eficiente durante el curso de producción, lo cual contribuye a la reducción en el costo de producción.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2012069157 | 2012-03-26 | ||
PCT/JP2013/058519 WO2013146649A1 (ja) | 2012-03-26 | 2013-03-25 | ジクアホソル含有点眼液 |
Publications (2)
Publication Number | Publication Date |
---|---|
MX2014011468A MX2014011468A (es) | 2015-01-12 |
MX353874B true MX353874B (es) | 2018-02-01 |
Family
ID=49259901
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2014011468A MX353874B (es) | 2012-03-26 | 2013-03-25 | Gotas para los ojos que contienen diquafosol. |
Country Status (26)
Country | Link |
---|---|
US (4) | US9486529B2 (es) |
EP (2) | EP3431092A1 (es) |
JP (6) | JP5625081B2 (es) |
KR (5) | KR101536885B1 (es) |
CN (2) | CN104203254A (es) |
AU (3) | AU2013241507A1 (es) |
BR (1) | BR112014023402B1 (es) |
CA (1) | CA2868390C (es) |
DK (1) | DK2832359T3 (es) |
EA (1) | EA028848B1 (es) |
ES (1) | ES2702575T3 (es) |
GE (1) | GEP20166470B (es) |
HK (2) | HK1204922A1 (es) |
HU (1) | HUE041671T2 (es) |
IN (1) | IN2014DN08632A (es) |
MX (1) | MX353874B (es) |
MY (1) | MY169816A (es) |
NZ (1) | NZ631041A (es) |
PH (1) | PH12014501955B1 (es) |
PL (1) | PL2832359T3 (es) |
PT (1) | PT2832359T (es) |
SG (2) | SG11201405799TA (es) |
TR (1) | TR201820073T4 (es) |
TW (4) | TWI723722B (es) |
UA (1) | UA113981C2 (es) |
WO (1) | WO2013146649A1 (es) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX353874B (es) | 2012-03-26 | 2018-02-01 | Santen Pharmaceutical Co Ltd | Gotas para los ojos que contienen diquafosol. |
MX2020003133A (es) * | 2014-01-10 | 2021-08-23 | Santen Pharmaceutical Co Ltd | Composicion farmaceutica que contiene compuesto de acido piridilaminoacetico. |
JP6104433B2 (ja) * | 2015-06-05 | 2017-03-29 | 参天製薬株式会社 | 水性点眼液 |
SG11201705138QA (en) * | 2014-12-25 | 2017-07-28 | Santen Pharmaceutical Co Ltd | Aqueous ophthalmic solution |
RU2742032C2 (ru) * | 2015-06-05 | 2021-02-01 | Сантен Фармасьютикал Ко., Лтд. | Терапевтическое средство против сухости глаз, характеризуемое нанесением на глаза пациентов с сухостью глаз, носящих гибкие контактные линзы |
JPWO2017002827A1 (ja) * | 2015-06-29 | 2018-04-26 | ヤマサ醤油株式会社 | P1,p4−ビス(5’−ウリジル)テトラホスフェート結晶の保管方法 |
JP6688057B2 (ja) * | 2015-12-01 | 2020-04-28 | 日水製薬株式会社 | グラム染色用後染色試液及びグラム染色方法 |
KR20220163519A (ko) * | 2018-02-28 | 2022-12-09 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 및 양이온성 폴리머를 함유하는 안과용 조성물 |
CN108403625A (zh) * | 2018-04-11 | 2018-08-17 | 东莞解石医药科技有限公司 | 一种含有螯合剂的地夸磷索四钠滴眼液 |
KR20240049646A (ko) * | 2019-08-27 | 2024-04-16 | 산텐 세이야꾸 가부시키가이샤 | 디쿠아포솔 또는 그 염 및 폴리비닐피롤리돈을 함유하는 수성 안과용 조성물 |
CN113720924A (zh) * | 2020-05-25 | 2021-11-30 | 南京帝昌医药科技有限公司 | 一种地夸磷索四钠的含量及有关物质检测方法 |
WO2022107791A1 (ja) * | 2020-11-18 | 2022-05-27 | 参天製薬株式会社 | ポリヘキサメチレンビグアナイドまたはその塩を含有する水性点眼液 |
WO2022107790A1 (ja) * | 2020-11-18 | 2022-05-27 | 参天製薬株式会社 | アルキルジアミノエチルグリシンまたはその塩を含有する水性点眼液 |
KR102548710B1 (ko) | 2020-12-24 | 2023-06-28 | 주식회사 종근당 | 디쿠아포솔 또는 이의 약제학적으로 허용가능한 염과 토코페롤을 함유하는 건성안 예방 또는 치료용 약제학적 조성물 |
CN112933040A (zh) * | 2021-02-04 | 2021-06-11 | 合肥博思科创医药科技有限公司 | 一种舒更葡糖钠注射液的制备方法 |
WO2023195718A1 (ko) * | 2022-04-04 | 2023-10-12 | 서울대학교산학협력단 | 감미 억제용 조성물 및 식품의 감미 억제 방법 |
CN117838628B (zh) * | 2024-03-01 | 2024-05-28 | 广州市桐晖药业有限公司 | 一种地夸磷索钠滴眼液及其制备方法 |
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SG10201508591UA (en) * | 2010-12-28 | 2015-11-27 | Santen Pharmaceutical Co Ltd | Ophthalmic solution comprising diquafosol, method for producing the same, and method for inhibiting formation of insoluble precipitate |
WO2012141334A1 (en) * | 2011-04-12 | 2012-10-18 | R-Tech Ueno, Ltd. | Aqueous ophthalmic composition |
MX353874B (es) | 2012-03-26 | 2018-02-01 | Santen Pharmaceutical Co Ltd | Gotas para los ojos que contienen diquafosol. |
US20150057226A1 (en) | 2012-03-26 | 2015-02-26 | Dilafor Ab | Method for treatment of labor arrest |
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2013
- 2013-03-25 MX MX2014011468A patent/MX353874B/es active IP Right Grant
- 2013-03-25 MY MYPI2014002576A patent/MY169816A/en unknown
- 2013-03-25 TR TR2018/20073T patent/TR201820073T4/tr unknown
- 2013-03-25 TW TW109100132A patent/TWI723722B/zh active
- 2013-03-25 KR KR1020147028142A patent/KR101536885B1/ko active IP Right Review Request
- 2013-03-25 CN CN201380016616.1A patent/CN104203254A/zh active Pending
- 2013-03-25 JP JP2013062270A patent/JP5625081B2/ja active Active
- 2013-03-25 PT PT13770386T patent/PT2832359T/pt unknown
- 2013-03-25 AU AU2013241507A patent/AU2013241507A1/en not_active Abandoned
- 2013-03-25 BR BR112014023402-7A patent/BR112014023402B1/pt not_active IP Right Cessation
- 2013-03-25 TW TW106124911A patent/TWI692364B/zh active
- 2013-03-25 PL PL13770386T patent/PL2832359T3/pl unknown
- 2013-03-25 EP EP18193430.8A patent/EP3431092A1/en not_active Withdrawn
- 2013-03-25 KR KR1020157004372A patent/KR101875845B1/ko active IP Right Review Request
- 2013-03-25 HU HUE13770386A patent/HUE041671T2/hu unknown
- 2013-03-25 KR KR1020187037979A patent/KR20190002751A/ko active Application Filing
- 2013-03-25 CN CN202110358504.0A patent/CN113018259A/zh active Pending
- 2013-03-25 NZ NZ631041A patent/NZ631041A/en not_active IP Right Cessation
- 2013-03-25 SG SG11201405799TA patent/SG11201405799TA/en unknown
- 2013-03-25 GE GEAP201313609A patent/GEP20166470B/en unknown
- 2013-03-25 CA CA2868390A patent/CA2868390C/en active Active
- 2013-03-25 TW TW102110422A patent/TWI625135B/zh active
- 2013-03-25 KR KR1020187018799A patent/KR101935484B1/ko active IP Right Review Request
- 2013-03-25 TW TW109124203A patent/TWI757799B/zh active
- 2013-03-25 ES ES13770386T patent/ES2702575T3/es active Active
- 2013-03-25 DK DK13770386.4T patent/DK2832359T3/en active
- 2013-03-25 SG SG10201607872PA patent/SG10201607872PA/en unknown
- 2013-03-25 US US14/386,169 patent/US9486529B2/en active Active
- 2013-03-25 IN IN8632DEN2014 patent/IN2014DN08632A/en unknown
- 2013-03-25 EA EA201491771A patent/EA028848B1/ru unknown
- 2013-03-25 WO PCT/JP2013/058519 patent/WO2013146649A1/ja active Application Filing
- 2013-03-25 KR KR1020207022714A patent/KR20200096708A/ko not_active Application Discontinuation
- 2013-03-25 EP EP13770386.4A patent/EP2832359B1/en active Active
- 2013-03-25 UA UAA201411576A patent/UA113981C2/uk unknown
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2014
- 2014-04-14 JP JP2014082821A patent/JP6126041B2/ja active Active
- 2014-09-01 PH PH12014501955A patent/PH12014501955B1/en unknown
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2015
- 2015-06-08 HK HK15105452.3A patent/HK1204922A1/xx unknown
- 2015-08-04 HK HK15107460.9A patent/HK1206648A1/xx unknown
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2016
- 2016-02-23 AU AU2016201110A patent/AU2016201110B2/en not_active Ceased
- 2016-02-23 AU AU2016201111A patent/AU2016201111A1/en not_active Withdrawn
- 2016-10-10 US US15/289,273 patent/US10071113B2/en active Active
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2017
- 2017-04-05 JP JP2017075167A patent/JP6389544B2/ja active Active
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2018
- 2018-02-07 JP JP2018020154A patent/JP6483299B2/ja active Active
- 2018-08-14 US US16/103,328 patent/US10632139B2/en not_active Expired - Fee Related
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2019
- 2019-02-12 JP JP2019022692A patent/JP7042762B2/ja active Active
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2020
- 2020-03-16 US US16/819,974 patent/US11166974B2/en active Active
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2022
- 2022-03-14 JP JP2022039183A patent/JP7447176B2/ja active Active
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