MX2011008948A - 3h-imidazo[4,5-c]piridina-6-carboxamidas como agentes antiinflamatorios. - Google Patents

3h-imidazo[4,5-c]piridina-6-carboxamidas como agentes antiinflamatorios.

Info

Publication number
MX2011008948A
MX2011008948A MX2011008948A MX2011008948A MX2011008948A MX 2011008948 A MX2011008948 A MX 2011008948A MX 2011008948 A MX2011008948 A MX 2011008948A MX 2011008948 A MX2011008948 A MX 2011008948A MX 2011008948 A MX2011008948 A MX 2011008948A
Authority
MX
Mexico
Prior art keywords
carboxamides
imidazo
pyridine
inflammatory agents
compounds
Prior art date
Application number
MX2011008948A
Other languages
English (en)
Inventor
Dirk Stenkamp
Kirsten Arndt
Henri Doods
Roland Pfau
Henning Priepke
Juergen Mack
Klaus Klinder
Raimund Kuelzer
Dimitrijs Lubriks
Edgars Suna
Benjamin Pelcman
Robert Roenn
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42111729&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2011008948(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of MX2011008948A publication Critical patent/MX2011008948A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

La presente invención se refiere a compuestos de fórmula general I (ver fórmula (I)) en la que A, L, M, Q2, Q3, Q4, R1, R5, Ra, Rb, Rc, W, X, Y, Z1, Z2, Z3 se definen en la descripción, sus sales, particularmente sus sales fisiológicamente aceptables. Los compuestos tienen utilidad potencial en el tratamiento y/o la prevención de enfermedades inflamatorias y afecciones asociadas, en particular, en el tratamiento y/o la prevención del dolor. La invención también se refiere al uso de dichos compuestos como medicamentos, a composiciones farmacéuticas que los contienen y a su preparación.
MX2011008948A 2009-03-05 2010-03-05 3h-imidazo[4,5-c]piridina-6-carboxamidas como agentes antiinflamatorios. MX2011008948A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09154414 2009-03-05
EP09179618 2009-12-17
PCT/EP2010/052799 WO2010100249A1 (en) 2009-03-05 2010-03-05 3h-imidazo [4, 5 -c] pyridine- 6 -carboxamides as anti- inflammatory agents

Publications (1)

Publication Number Publication Date
MX2011008948A true MX2011008948A (es) 2011-09-27

Family

ID=42111729

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2011008948A MX2011008948A (es) 2009-03-05 2010-03-05 3h-imidazo[4,5-c]piridina-6-carboxamidas como agentes antiinflamatorios.

Country Status (37)

Country Link
US (3) US20100256188A1 (es)
EP (1) EP2403852B8 (es)
JP (1) JP5433708B2 (es)
KR (1) KR20110123764A (es)
CN (1) CN102341395B (es)
AP (1) AP2806A (es)
AR (1) AR075789A1 (es)
AU (1) AU2010220263B2 (es)
BR (1) BRPI1009118A2 (es)
CA (1) CA2753149A1 (es)
CL (1) CL2011002180A1 (es)
CO (1) CO6450668A2 (es)
CY (1) CY1115959T1 (es)
DK (1) DK2403852T3 (es)
EA (1) EA020282B1 (es)
EC (1) ECSP11011324A (es)
ES (1) ES2528730T3 (es)
GE (1) GEP20146034B (es)
HK (1) HK1163064A1 (es)
HR (1) HRP20150096T1 (es)
IL (1) IL214033A0 (es)
MA (1) MA33239B1 (es)
ME (1) ME02117B (es)
MX (1) MX2011008948A (es)
MY (1) MY161092A (es)
NZ (1) NZ594589A (es)
PE (1) PE20120589A1 (es)
PL (1) PL2403852T3 (es)
PT (1) PT2403852E (es)
RS (1) RS53757B1 (es)
SG (1) SG174250A1 (es)
SI (1) SI2403852T1 (es)
SM (1) SMT201500053B (es)
TN (1) TN2011000446A1 (es)
TW (1) TWI466869B (es)
UY (1) UY32470A (es)
WO (1) WO2010100249A1 (es)

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