MX2011006524A - Profarmacos de peptido de la superfamilia de glucagon basado en amida. - Google Patents
Profarmacos de peptido de la superfamilia de glucagon basado en amida.Info
- Publication number
- MX2011006524A MX2011006524A MX2011006524A MX2011006524A MX2011006524A MX 2011006524 A MX2011006524 A MX 2011006524A MX 2011006524 A MX2011006524 A MX 2011006524A MX 2011006524 A MX2011006524 A MX 2011006524A MX 2011006524 A MX2011006524 A MX 2011006524A
- Authority
- MX
- Mexico
- Prior art keywords
- glucagon superfamily
- amide based
- superfamily peptide
- peptide prodrugs
- based glucagon
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
Abstract
Se proporcionan formulaciones de profármacos de péptidos de la superfamilia de glucagón en donde el péptido de la superfamilia de glucagón ha sido modificado por la unión de un dipéptido a la superfamilia de glucagón a través de una ligadura de unión amida. Los profármacos divulgados en el presente han prolongado las semividas y son convertidos a la forma activa en condiciones fisiológicas a través de una reacción no enzimática dirigida por inestabilidad química.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13921008P | 2008-12-19 | 2008-12-19 | |
US14427109P | 2009-01-13 | 2009-01-13 | |
US18755609P | 2009-06-16 | 2009-06-16 | |
PCT/US2009/068745 WO2010071807A1 (en) | 2008-12-19 | 2009-12-18 | Amide based glucagon superfamily peptide prodrugs |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2011006524A true MX2011006524A (es) | 2011-08-17 |
Family
ID=42269125
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2011006524A MX2011006524A (es) | 2008-12-19 | 2009-12-18 | Profarmacos de peptido de la superfamilia de glucagon basado en amida. |
Country Status (17)
Country | Link |
---|---|
US (1) | US8969288B2 (es) |
EP (2) | EP2376097A4 (es) |
JP (2) | JP2012512903A (es) |
KR (1) | KR20110110174A (es) |
CN (1) | CN102325539A (es) |
AR (1) | AR074811A1 (es) |
AU (1) | AU2009327418A1 (es) |
BR (1) | BRPI0922969A2 (es) |
CA (1) | CA2747499A1 (es) |
CL (1) | CL2011001498A1 (es) |
IL (1) | IL213113A (es) |
MX (1) | MX2011006524A (es) |
PE (1) | PE20120332A1 (es) |
RU (1) | RU2550696C2 (es) |
SG (1) | SG172291A1 (es) |
TW (1) | TWI489992B (es) |
WO (1) | WO2010071807A1 (es) |
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-
2009
- 2009-12-18 KR KR1020117016193A patent/KR20110110174A/ko active IP Right Grant
- 2009-12-18 MX MX2011006524A patent/MX2011006524A/es active IP Right Grant
- 2009-12-18 CA CA2747499A patent/CA2747499A1/en not_active Abandoned
- 2009-12-18 JP JP2011542487A patent/JP2012512903A/ja active Pending
- 2009-12-18 EP EP09833836A patent/EP2376097A4/en not_active Ceased
- 2009-12-18 PE PE2011001238A patent/PE20120332A1/es not_active Application Discontinuation
- 2009-12-18 AU AU2009327418A patent/AU2009327418A1/en not_active Abandoned
- 2009-12-18 RU RU2011129784/04A patent/RU2550696C2/ru not_active IP Right Cessation
- 2009-12-18 AR ARP090104993A patent/AR074811A1/es not_active Application Discontinuation
- 2009-12-18 US US13/130,962 patent/US8969288B2/en active Active
- 2009-12-18 CN CN2009801573173A patent/CN102325539A/zh active Pending
- 2009-12-18 SG SG2011045283A patent/SG172291A1/en unknown
- 2009-12-18 EP EP16164599.9A patent/EP3075385A1/en not_active Withdrawn
- 2009-12-18 WO PCT/US2009/068745 patent/WO2010071807A1/en active Application Filing
- 2009-12-18 BR BRPI0922969A patent/BRPI0922969A2/pt not_active IP Right Cessation
- 2009-12-18 TW TW098143717A patent/TWI489992B/zh not_active IP Right Cessation
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2011
- 2011-05-24 IL IL213113A patent/IL213113A/en not_active IP Right Cessation
- 2011-06-17 CL CL2011001498A patent/CL2011001498A1/es unknown
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WO2010071807A1 (en) | 2010-06-24 |
PE20120332A1 (es) | 2012-04-14 |
BRPI0922969A2 (pt) | 2019-09-24 |
CA2747499A1 (en) | 2010-06-24 |
RU2011129784A (ru) | 2013-01-27 |
JP2012512903A (ja) | 2012-06-07 |
TWI489992B (zh) | 2015-07-01 |
TW201028162A (en) | 2010-08-01 |
US20110288003A1 (en) | 2011-11-24 |
EP2376097A4 (en) | 2012-10-03 |
EP3075385A1 (en) | 2016-10-05 |
IL213113A (en) | 2017-09-28 |
AR074811A1 (es) | 2011-02-16 |
RU2550696C2 (ru) | 2015-05-10 |
KR20110110174A (ko) | 2011-10-06 |
IL213113A0 (en) | 2011-07-31 |
US8969288B2 (en) | 2015-03-03 |
EP2376097A1 (en) | 2011-10-19 |
AU2009327418A1 (en) | 2010-06-24 |
SG172291A1 (en) | 2011-07-28 |
CN102325539A (zh) | 2012-01-18 |
JP2015180649A (ja) | 2015-10-15 |
CL2011001498A1 (es) | 2012-03-09 |
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