MX2009013213A - Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa. - Google Patents

Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa.

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Publication number
MX2009013213A
MX2009013213A MX2009013213A MX2009013213A MX2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A
Authority
MX
Mexico
Prior art keywords
compounds
kinase inhibitors
heteroaryl substituted
substituted indazoles
relates
Prior art date
Application number
MX2009013213A
Other languages
English (en)
Spanish (es)
Inventor
Douglas M Kalvin
Lu Wang
Alan F Gasiecki
Vijaya J Gracias
Irini Akritopoulou-Zanze
Biqin Li
Jyoti R Patel
Qi Shuai
Sean C Turner
Stevan W Djuric
Margaretha Bakker
Anil Vasudevan
Melissa J Michmerhuizen
Kathy Sarris
Adrian Hobson
Nicole Teusch
Helmut Mack
Brian D Wakefield
Eric T Johnson
Peter J Kovar
Andrew J Long
Nigel St John Moore
Dawn George
Kristine Frank
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2009013213A publication Critical patent/MX2009013213A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Orthopedic Medicine & Surgery (AREA)
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  • Urology & Nephrology (AREA)
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  • Hematology (AREA)
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MX2009013213A 2007-06-08 2008-06-04 Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa. MX2009013213A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93396007P 2007-06-08 2007-06-08
PCT/US2008/065727 WO2008154241A1 (fr) 2007-06-08 2008-06-04 Indazoles à substitution 5-hétéroaryle servant d'inhibiteurs de kinases

Publications (1)

Publication Number Publication Date
MX2009013213A true MX2009013213A (es) 2010-03-30

Family

ID=39951673

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2009013213A MX2009013213A (es) 2007-06-08 2008-06-04 Indazoles 5-sustituidos 5-heteroarilo como inhibidores de cinasa.

Country Status (13)

Country Link
EP (1) EP2167491A1 (fr)
JP (2) JP5451602B2 (fr)
KR (1) KR20100032886A (fr)
CN (1) CN101790526A (fr)
AU (1) AU2008262038A1 (fr)
BR (1) BRPI0811065A2 (fr)
CA (1) CA2689117A1 (fr)
IL (1) IL202318A0 (fr)
MX (1) MX2009013213A (fr)
RU (1) RU2487873C2 (fr)
SG (1) SG182187A1 (fr)
WO (1) WO2008154241A1 (fr)
ZA (1) ZA200908624B (fr)

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WO2009011880A2 (fr) 2007-07-17 2009-01-22 Amgen Inc. Modulateurs hétérocycliques de pkb
WO2009011871A2 (fr) 2007-07-17 2009-01-22 Amgen Inc. Thiadiazoles modulateurs de l'activité de pkb
JPWO2009028543A1 (ja) * 2007-08-30 2010-12-02 武田薬品工業株式会社 置換ピラゾール誘導体
MX2010009268A (es) 2008-02-21 2010-09-14 Schering Corp Compuestos que son inhibidores de erk.
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JP5743897B2 (ja) * 2008-11-20 2015-07-01 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ 化合物
SI2464232T1 (sl) 2009-08-10 2016-03-31 Samumed, Llc. Indazolovi inhibitorji signalne poti WNT in njihova terapevtska uporaba
WO2011084486A1 (fr) 2009-12-21 2011-07-14 Epitherix, Llc 1h-pyrazolo[3,4-b]pyridines et leurs utilisations thérapeutiques
UY33213A (es) * 2010-02-18 2011-09-30 Almirall Sa Derivados de pirazol como inhibidores de jak
KR101233082B1 (ko) 2010-02-25 2013-02-14 주식회사 이큐스앤자루 신규한 이미다졸피라진 유도체 화합물 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는 항바이러스 치료용 약학적 조성물
US9181233B2 (en) 2010-03-03 2015-11-10 Probiodrug Ag Inhibitors of glutaminyl cyclase
JPWO2011136264A1 (ja) * 2010-04-28 2013-07-22 第一三共株式会社 ［５，６］複素環化合物
WO2011140333A1 (fr) 2010-05-07 2011-11-10 The Board Of Trustees Of The Leland Stanford Junior University Identification de stabilisants de protéines multimériques
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US9090592B2 (en) * 2010-12-30 2015-07-28 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as glycogen synthase kinase-3 inhibitors
CN102675286B (zh) * 2011-03-07 2015-08-19 中国科学院上海药物研究所 一类吲唑类化合物及其制备方法、用途和药物组合物
EA024890B1 (ru) * 2011-04-07 2016-10-31 Байер Интеллектчуал Проперти Гмбх Имидазопиридазины в качестве ингибиторов akt киназы
EP2742046A1 (fr) * 2011-08-12 2014-06-18 F.Hoffmann-La Roche Ag Composés de pyrazolo[3,4-c]pyridine et procédés d'utilisation
CN103929963A (zh) 2011-09-14 2014-07-16 萨穆梅德有限公司 吲唑-3-羧酰胺及其作为WNT/β-CATENIN信号传导通路抑制剂的用途
ES2675506T3 (es) 2011-12-27 2018-07-11 Bayer Cropscience Aktiengesellschaft Derivados de heteroarilpiperidina y de heteroarilpiperazina como fungicidas
KR20140130124A (ko) * 2012-02-21 2014-11-07 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 글리코겐 합성효소 키나아제 3 베타 억제제로서 1h-인다졸-3-카복사미드 화합물
PH12017500997A1 (en) 2012-04-04 2018-02-19 Samumed Llc Indazole inhibitors of the wnt signal pathway and therapeutic uses thereof
RS59668B1 (sr) 2012-05-04 2020-01-31 Samumed Llc 1h-pirazolo[3,4-b]piridini i njihova terapeutska upotreba
TW201406758A (zh) * 2012-06-28 2014-02-16 Daiichi Sankyo Co Ltd 三環性化合物
CN105120862A (zh) 2013-01-08 2015-12-02 萨穆梅德有限公司 Wnt信号途径的3-(苯并咪唑-2-基)-吲唑抑制剂及其治疗应用
EP2964221B1 (fr) 2013-03-04 2017-12-06 Merck Sharp & Dohme Corp. Composés inhibant l'activité enzymatique de la kinase à répétition riche en leucine
WO2014134772A1 (fr) 2013-03-04 2014-09-12 Merck Sharp & Dohme Corp. Composés inhibant l'activité enzymatique de la kinase à séquence répétée riche en leucine
WO2014134774A1 (fr) 2013-03-04 2014-09-12 Merck Sharp & Dohme Corp. Composés inhibant l'activité enzymatique de la kinase à séquence répétée riche en leucine
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