MX2009013213A - 5-heteroaryl substituted indazoles as kinase inhibitors. - Google Patents

5-heteroaryl substituted indazoles as kinase inhibitors.

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Publication number
MX2009013213A
MX2009013213A MX2009013213A MX2009013213A MX2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A MX 2009013213 A MX2009013213 A MX 2009013213A
Authority
MX
Mexico
Prior art keywords
compounds
kinase inhibitors
heteroaryl substituted
substituted indazoles
relates
Prior art date
Application number
MX2009013213A
Other languages
Spanish (es)
Inventor
Douglas M Kalvin
Lu Wang
Alan F Gasiecki
Vijaya J Gracias
Irini Akritopoulou-Zanze
Biqin Li
Jyoti R Patel
Qi Shuai
Sean C Turner
Stevan W Djuric
Margaretha Bakker
Anil Vasudevan
Melissa J Michmerhuizen
Kathy Sarris
Adrian Hobson
Nicole Teusch
Helmut Mack
Brian D Wakefield
Eric T Johnson
Peter J Kovar
Andrew J Long
Nigel St John Moore
Dawn George
Kristine Frank
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of MX2009013213A publication Critical patent/MX2009013213A/en

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    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts, wherein A, R1, R2, R3 and m, are defined in the description. The present invention relates also to methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as Glycogen Synthase kinase 3 (GSK-3), Rho kinase (ROCK), Janus Kinases (JAK), AKT, PAK4, PLK, CK2, KDR, MK2, JNK1, aurora, pim 1 and nek 2.
MX2009013213A 2007-06-08 2008-06-04 5-heteroaryl substituted indazoles as kinase inhibitors. MX2009013213A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93396007P 2007-06-08 2007-06-08
PCT/US2008/065727 WO2008154241A1 (en) 2007-06-08 2008-06-04 5-heteroaryl substituted indazoles as kinase inhibitors

Publications (1)

Publication Number Publication Date
MX2009013213A true MX2009013213A (en) 2010-03-30

Family

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MX2009013213A MX2009013213A (en) 2007-06-08 2008-06-04 5-heteroaryl substituted indazoles as kinase inhibitors.

Country Status (13)

Country Link
EP (1) EP2167491A1 (en)
JP (2) JP5451602B2 (en)
KR (1) KR20100032886A (en)
CN (1) CN101790526A (en)
AU (1) AU2008262038A1 (en)
BR (1) BRPI0811065A2 (en)
CA (1) CA2689117A1 (en)
IL (1) IL202318A0 (en)
MX (1) MX2009013213A (en)
RU (1) RU2487873C2 (en)
SG (1) SG182187A1 (en)
WO (1) WO2008154241A1 (en)
ZA (1) ZA200908624B (en)

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