MX2009009792A - Compuestos de fenil amino pirimidina y usos de los mismos. - Google Patents
Compuestos de fenil amino pirimidina y usos de los mismos.Info
- Publication number
- MX2009009792A MX2009009792A MX2009009792A MX2009009792A MX2009009792A MX 2009009792 A MX2009009792 A MX 2009009792A MX 2009009792 A MX2009009792 A MX 2009009792A MX 2009009792 A MX2009009792 A MX 2009009792A MX 2009009792 A MX2009009792 A MX 2009009792A
- Authority
- MX
- Mexico
- Prior art keywords
- diseases
- phenyl amino
- pyrimidine compounds
- amino pyrimidine
- kinases
- Prior art date
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
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Abstract
La presente invención se relaciona a compuestos de fenil amino pirimidina que son inhibidores de proteína quinasas que incluyen quinasas de JAK. En particular los compuestos son selectivos para las quinasas de JAK2. Los inhibidores de quinasa se pueden utilizar en el tratamiento de enfermedades asociadas con quinasa tales como enfermedades inmunológicas e inflamatorias que incluyen transplantes de órganos; enfermedades hiperproliferativas que incluyen cáncer y enfermedades mieloproliferativas; enfermedades virales; enfermedades metabólicas; y enfermedades vasculares.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US89426407P | 2007-03-12 | 2007-03-12 | |
US1625207P | 2007-12-21 | 2007-12-21 | |
PCT/AU2008/000339 WO2008109943A1 (en) | 2007-03-12 | 2008-03-12 | Phenyl amino pyrimidine compounds and uses thereof |
Publications (1)
Publication Number | Publication Date |
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MX2009009792A true MX2009009792A (es) | 2009-09-23 |
Family
ID=39758909
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009009792A MX2009009792A (es) | 2007-03-12 | 2008-03-12 | Compuestos de fenil amino pirimidina y usos de los mismos. |
Country Status (22)
Country | Link |
---|---|
US (5) | US8486941B2 (es) |
EP (2) | EP3023422A1 (es) |
JP (5) | JP2010520892A (es) |
KR (3) | KR101737753B1 (es) |
CN (2) | CN101861313B (es) |
AU (1) | AU2008226327B2 (es) |
BR (2) | BRPI0808888B8 (es) |
CA (1) | CA2702650C (es) |
CY (1) | CY1117180T1 (es) |
DK (1) | DK2152701T3 (es) |
ES (1) | ES2557930T3 (es) |
HK (1) | HK1149749A1 (es) |
HR (1) | HRP20151386T1 (es) |
HU (1) | HUE029188T2 (es) |
MX (1) | MX2009009792A (es) |
PL (1) | PL2152701T3 (es) |
PT (1) | PT2152701E (es) |
RS (1) | RS54533B1 (es) |
RU (1) | RU2498983C2 (es) |
SI (1) | SI2152701T1 (es) |
WO (1) | WO2008109943A1 (es) |
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