MX2008007049A - Inhibidores de c-met y usos de los mismos. - Google Patents
Inhibidores de c-met y usos de los mismos.Info
- Publication number
- MX2008007049A MX2008007049A MX2008007049A MX2008007049A MX2008007049A MX 2008007049 A MX2008007049 A MX 2008007049A MX 2008007049 A MX2008007049 A MX 2008007049A MX 2008007049 A MX2008007049 A MX 2008007049A MX 2008007049 A MX2008007049 A MX 2008007049A
- Authority
- MX
- Mexico
- Prior art keywords
- aliphatic
- optionally substituted
- dmso
- compound according
- nmr
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74085905P | 2005-11-30 | 2005-11-30 | |
| US74074105P | 2005-11-30 | 2005-11-30 | |
| US74073705P | 2005-11-30 | 2005-11-30 | |
| PCT/US2006/045847 WO2007064797A2 (en) | 2005-11-30 | 2006-11-30 | Inhibitors of c-met and uses thereof |
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| JP (1) | JP5144532B2 (https=) |
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| BR (1) | BRPI0619252A2 (https=) |
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| IL (1) | IL191623A0 (https=) |
| MX (1) | MX2008007049A (https=) |
| NO (1) | NO20082880L (https=) |
| NZ (1) | NZ568666A (https=) |
| WO (1) | WO2007064797A2 (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10038019A1 (de) | 2000-08-04 | 2002-02-14 | Bayer Ag | Substituierte Triazolopyrid(az)ine |
| US7122548B2 (en) * | 2003-07-02 | 2006-10-17 | Sugen, Inc. | Triazolotriazine compounds and uses thereof |
| HUE030390T2 (en) | 2005-12-21 | 2017-05-29 | Janssen Pharmaceutica Nv | Triazolopyridazines as tyrosine kinase modulators |
-
2006
- 2006-11-30 KR KR1020087015565A patent/KR20080080584A/ko not_active Ceased
- 2006-11-30 US US11/606,524 patent/US7728017B2/en not_active Expired - Fee Related
- 2006-11-30 BR BRPI0619252-1A patent/BRPI0619252A2/pt not_active Application Discontinuation
- 2006-11-30 WO PCT/US2006/045847 patent/WO2007064797A2/en not_active Ceased
- 2006-11-30 NZ NZ568666A patent/NZ568666A/en not_active IP Right Cessation
- 2006-11-30 AU AU2006320580A patent/AU2006320580B2/en not_active Ceased
- 2006-11-30 CA CA002630884A patent/CA2630884A1/en not_active Abandoned
- 2006-11-30 EP EP06838683A patent/EP1963329B1/en active Active
- 2006-11-30 MX MX2008007049A patent/MX2008007049A/es not_active Application Discontinuation
- 2006-11-30 JP JP2008543461A patent/JP5144532B2/ja not_active Expired - Fee Related
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- 2008-05-22 IL IL191623A patent/IL191623A0/en unknown
- 2008-06-30 NO NO20082880A patent/NO20082880L/no not_active Application Discontinuation
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2010
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| Publication number | Publication date |
|---|---|
| EP1963329B1 (en) | 2013-01-23 |
| BRPI0619252A2 (pt) | 2011-09-20 |
| IL191623A0 (en) | 2008-12-29 |
| US7728017B2 (en) | 2010-06-01 |
| CA2630884A1 (en) | 2007-06-07 |
| JP2009518296A (ja) | 2009-05-07 |
| US7998987B2 (en) | 2011-08-16 |
| AU2006320580A1 (en) | 2007-06-07 |
| AU2006320580B2 (en) | 2011-06-23 |
| JP5144532B2 (ja) | 2013-02-13 |
| NO20082880L (no) | 2008-09-01 |
| KR20080080584A (ko) | 2008-09-04 |
| NZ568666A (en) | 2011-09-30 |
| EP1963329A2 (en) | 2008-09-03 |
| US20100190774A1 (en) | 2010-07-29 |
| WO2007064797A3 (en) | 2007-12-13 |
| WO2007064797A2 (en) | 2007-06-07 |
| US20070191369A1 (en) | 2007-08-16 |
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