MEP89008A - Novel cyclosporin analog microemulsion preconcentrates - Google Patents
Novel cyclosporin analog microemulsion preconcentratesInfo
- Publication number
- MEP89008A MEP89008A MEP-890/08A MEP89008A MEP89008A ME P89008 A MEP89008 A ME P89008A ME P89008 A MEP89008 A ME P89008A ME P89008 A MEP89008 A ME P89008A
- Authority
- ME
- Montenegro
- Prior art keywords
- microemulsion preconcentrates
- novel cyclosporin
- cyclosporin analog
- cyclosporin
- analog microemulsion
- Prior art date
Links
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical class CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title abstract 6
- 239000004530 micro-emulsion Substances 0.000 title 1
- 229930105110 Cyclosporin A Natural products 0.000 abstract 3
- 108010036949 Cyclosporine Proteins 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229960001265 ciclosporin Drugs 0.000 abstract 2
- 238000009472 formulation Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
- C07K7/645—Cyclosporins; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
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-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Dispersion Chemistry (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Ophthalmology & Optometry (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US34620101P | 2001-10-19 | 2001-10-19 | |
| US37059702P | 2002-04-05 | 2002-04-05 | |
| PCT/CA2002/001561 WO2003032949A1 (en) | 2001-10-19 | 2002-10-17 | Novel cyclosporin analog microemulsion preconcentrates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MEP89008A true MEP89008A (en) | 2011-12-20 |
Family
ID=26994747
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MEP-890/08A MEP89008A (en) | 2001-10-19 | 2002-10-17 | Novel cyclosporin analog microemulsion preconcentrates |
Country Status (28)
| Country | Link |
|---|---|
| US (5) | US7060672B2 (enExample) |
| EP (2) | EP1435910B9 (enExample) |
| JP (3) | JP2005506990A (enExample) |
| KR (1) | KR100978836B1 (enExample) |
| CN (1) | CN1274294C (enExample) |
| AR (1) | AR036852A1 (enExample) |
| AT (1) | ATE437629T1 (enExample) |
| AU (1) | AU2002333098B2 (enExample) |
| BR (1) | BR0213661A (enExample) |
| CA (1) | CA2461730C (enExample) |
| CO (1) | CO5580835A2 (enExample) |
| DE (1) | DE60233150D1 (enExample) |
| DK (1) | DK1435910T3 (enExample) |
| ES (1) | ES2330625T3 (enExample) |
| HR (1) | HRP20040354B1 (enExample) |
| IL (3) | IL160761A0 (enExample) |
| MA (1) | MA26221A1 (enExample) |
| ME (1) | MEP89008A (enExample) |
| MX (1) | MXPA04003623A (enExample) |
| MY (1) | MY145753A (enExample) |
| NO (1) | NO20042028L (enExample) |
| NZ (1) | NZ531946A (enExample) |
| PL (1) | PL206018B1 (enExample) |
| PT (1) | PT1435910E (enExample) |
| RU (1) | RU2317067C2 (enExample) |
| TN (1) | TNSN04070A1 (enExample) |
| WO (1) | WO2003032949A1 (enExample) |
| ZA (1) | ZA200402268B (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PL206018B1 (pl) * | 2001-10-19 | 2010-06-30 | Isotechnika Inc | Preparat farmaceutyczny, sposób jego wytwarzania, mikroemulsja i zastosowanie tego preparatu farmaceutycznego |
| JP2006524232A (ja) | 2003-03-17 | 2006-10-26 | アルバニー モレキュラー リサーチ インコーポレーティッド | 新規サイクロスポリン |
| GB0307440D0 (en) * | 2003-03-31 | 2003-05-07 | Novartis Ag | Organic compounds |
| US20050256097A1 (en) * | 2004-05-11 | 2005-11-17 | Kosan Biosciences, Inc. | Pharmaceutical solution formulations containing 17-AAG |
| WO2006039164A2 (en) | 2004-09-29 | 2006-04-13 | Amr Technology, Inc. | Novel cyclosporin analogues and their pharmaceutical uses |
| EP1809656A4 (en) * | 2004-09-29 | 2009-03-25 | Amr Technology Inc | CYCLOSPORINAL KINANALOGA AND ITS PHARMACEUTICAL APPLICATIONS |
| US7361636B2 (en) | 2004-10-06 | 2008-04-22 | Amr Technology, Inc. | Cyclosporin alkynes and their utility as pharmaceutical agents |
| WO2008121096A1 (en) * | 2005-05-19 | 2008-10-09 | The Board Of Governors For Higher Education | Monitoring cyclosporine in saliva |
| CA2645080A1 (en) * | 2006-03-07 | 2007-09-13 | Novavax,Inc. | Nanoemulsions of poorly soluble pharmaceutical active ingredients and methods of making the same |
| US10137083B2 (en) * | 2006-03-07 | 2018-11-27 | SGN Nanopharma Inc | Ophthalmic preparations |
| US11311477B2 (en) | 2006-03-07 | 2022-04-26 | Sgn Nanopharma Inc. | Ophthalmic preparations |
| US7696165B2 (en) * | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne analogues for preventing or treating viral-induced disorders |
| US7696166B2 (en) * | 2006-03-28 | 2010-04-13 | Albany Molecular Research, Inc. | Use of cyclosporin alkyne/alkene analogues for preventing or treating viral-induced disorders |
| EP2104498A2 (en) * | 2006-10-31 | 2009-09-30 | Wyeth | Liquid formulations of phospholipase enzyme inhibitors |
| BRPI0718030A2 (pt) * | 2006-10-31 | 2013-11-12 | Wyeth Corp | Formulações de inibidores de enzima de fosfolipase |
| JP5668476B2 (ja) * | 2007-10-08 | 2015-02-12 | オーリニア・ファーマシューティカルズ・インコーポレイテッドＡｕｒｉｎｉａ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ Ｉｎｃ． | カルシニューリン阻害剤またはｍＴＯＲ阻害剤を含む眼科用組成物 |
| MX2010010050A (es) | 2008-03-20 | 2011-03-15 | Virun Inc Star | Emulsiones que incluyen un derivado de polietilen glicol de tocoferol. |
| CA2715018C (en) * | 2008-03-20 | 2012-11-13 | Virun, Inc. | Vitamin e derivatives and their uses |
| US8252821B2 (en) * | 2009-04-14 | 2012-08-28 | Bristol-Myers Squibb Company | Bioavailable capsule compositions of amorphous alpha-(N-sulfonamido)acetamide compound |
| WO2010144194A1 (en) | 2009-06-09 | 2010-12-16 | Lux Biosciences, Inc. | Topical drug delivery systems for ophthalmic use |
| CN102652015B (zh) | 2009-12-10 | 2016-08-03 | 默克专利有限公司 | 包含寡肽、优选西仑吉肽的药物组合物 |
| CN103037708B (zh) * | 2010-03-23 | 2015-05-20 | 维尔恩公司 | 含有蔗糖脂肪酸酯的纳米乳液 |
| IT1404931B1 (it) * | 2010-06-11 | 2013-12-09 | Medivis S R L | Composizioni oftalmiche per la somministrazione di principi attivi liposolubili . |
| WO2011162802A1 (en) | 2010-06-21 | 2011-12-29 | Virun, Inc. | Compositions containing non-polar compounds |
| US20110319467A1 (en) * | 2010-06-23 | 2011-12-29 | Bhiku Patel | Absorption Enhancement of Statins and Omega Fatty Acids |
| RU2566984C2 (ru) * | 2010-06-25 | 2015-10-27 | Фирмениш Са | Система доставки пищевых компонентов |
| US9044394B2 (en) * | 2010-10-18 | 2015-06-02 | PruGen IP Holdings, Inc. | Bioavailability enhancement delivery composition |
| US20120095098A1 (en) * | 2010-10-18 | 2012-04-19 | Bhiku Patel | Bioavailability Enhancement Delivery System |
| HRP20190096T1 (hr) | 2010-12-15 | 2019-02-22 | Contravir Pharmaceuticals, Inc. | Molekule analoga ciklosporina modificirani na amino kiselini 1 i 3 |
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| SI2887923T1 (sl) | 2012-08-24 | 2023-09-29 | Sun Pharmaceutical Industries Limited | Oftalmična formulacija polioksilnega lipida ali polioksilne maščobne kisline in zdravljenje očesnih stanj |
| GB201222455D0 (en) * | 2012-12-13 | 2013-01-30 | Perioc Ltd | Novel pharmaceutical formulations and their use in the treatment of periodontaldisease |
| US9351517B2 (en) | 2013-03-15 | 2016-05-31 | Virun, Inc. | Formulations of water-soluble derivatives of vitamin E and compositions containing same |
| CA2942186C (en) | 2014-06-18 | 2023-06-27 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical composition comprising non-ionic surfactants |
| US9861611B2 (en) | 2014-09-18 | 2018-01-09 | Virun, Inc. | Formulations of water-soluble derivatives of vitamin E and soft gel compositions, concentrates and powders containing same |
| FI3373976T3 (fi) | 2015-11-10 | 2024-03-25 | Sun Pharmaceutical Ind Ltd | Topikaalisia formulaatioita ja niiden käyttöjä |
| WO2017151657A1 (en) | 2016-02-29 | 2017-09-08 | Ocular Technologies Sarl | Topical cyclosporine-containing formulations and uses thereof |
| US20200003785A1 (en) | 2016-12-01 | 2020-01-02 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Use of anti-uchl1 igg plasma concentration for diagnosing idiopathic steroid sensitive nephrotic syndrome |
| US20190224275A1 (en) | 2017-05-12 | 2019-07-25 | Aurinia Pharmaceuticals Inc. | Protocol for treatment of lupus nephritis |
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| WO2019077123A1 (en) | 2017-10-20 | 2019-04-25 | INSERM (Institut National de la Santé et de la Recherche Médicale) | METHODS AND KITS FOR IDENTIFYING WHETHER A SUBJECT IS REACHED OR RISK OF BEING WITH AUTOIMMUNE MYOPATHY |
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- 2004-04-16 TN TNP2004000070A patent/TNSN04070A1/en unknown
- 2004-04-19 CO CO04035664A patent/CO5580835A2/es not_active Application Discontinuation
- 2004-05-14 NO NO20042028A patent/NO20042028L/no not_active Application Discontinuation
-
2006
- 2006-03-13 US US11/375,532 patent/US7429562B2/en not_active Expired - Lifetime
-
2008
- 2008-08-22 US US12/197,199 patent/US7829533B2/en not_active Expired - Lifetime
- 2008-11-07 JP JP2008287205A patent/JP2009073850A/ja active Pending
- 2008-12-11 IL IL195892A patent/IL195892A/en active IP Right Grant
-
2010
- 2010-11-08 US US12/941,907 patent/US20110136744A1/en not_active Abandoned
-
2012
- 2012-05-24 JP JP2012118377A patent/JP2012158609A/ja active Pending
-
2014
- 2014-03-09 US US14/201,872 patent/US20140249092A1/en not_active Abandoned
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