IT1404931B1 - Composizioni oftalmiche per la somministrazione di principi attivi liposolubili . - Google Patents

Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .

Info

Publication number
IT1404931B1
IT1404931B1 ITRM2010A000322A ITRM20100322A IT1404931B1 IT 1404931 B1 IT1404931 B1 IT 1404931B1 IT RM2010A000322 A ITRM2010A000322 A IT RM2010A000322A IT RM20100322 A ITRM20100322 A IT RM20100322A IT 1404931 B1 IT1404931 B1 IT 1404931B1
Authority
IT
Italy
Prior art keywords
lipo
administration
active principles
soluble active
ophthalmic compositions
Prior art date
Application number
ITRM2010A000322A
Other languages
English (en)
Inventor
Melina Cro
Danilo Aleo
Sergio Mangiafico
Maria Grazia Saita
Original Assignee
Medivis S R L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medivis S R L filed Critical Medivis S R L
Priority to ITRM2010A000322A priority Critical patent/IT1404931B1/it
Priority to PCT/IT2011/000196 priority patent/WO2011154985A1/en
Priority to CA2802162A priority patent/CA2802162A1/en
Priority to CN2011800359894A priority patent/CN103079543A/zh
Priority to EP11739184.7A priority patent/EP2579845B1/en
Priority to MX2012014443A priority patent/MX2012014443A/es
Priority to RU2013100984/15A priority patent/RU2013100984A/ru
Publication of ITRM20100322A1 publication Critical patent/ITRM20100322A1/it
Priority to US13/711,449 priority patent/US20130108674A1/en
Application granted granted Critical
Publication of IT1404931B1 publication Critical patent/IT1404931B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
ITRM2010A000322A 2010-06-11 2010-06-11 Composizioni oftalmiche per la somministrazione di principi attivi liposolubili . IT1404931B1 (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
ITRM2010A000322A IT1404931B1 (it) 2010-06-11 2010-06-11 Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .
PCT/IT2011/000196 WO2011154985A1 (en) 2010-06-11 2011-06-13 Ophthalmic compositions for the administration of liposoluble acitve ingredients
CA2802162A CA2802162A1 (en) 2010-06-11 2011-06-13 Ophthalmic compositions for the administration of liposoluble acitve ingredients
CN2011800359894A CN103079543A (zh) 2010-06-11 2011-06-13 用于脂溶性活性成分给药的眼用组合物
EP11739184.7A EP2579845B1 (en) 2010-06-11 2011-06-13 Ophthalmic compositions for the administration of liposoluble acitve ingredients
MX2012014443A MX2012014443A (es) 2010-06-11 2011-06-13 Composiciones oftalmicas para la administracion de ingredientes activos liposolubles.
RU2013100984/15A RU2013100984A (ru) 2010-06-11 2011-06-13 Офтальмологические композиции для введения активных жирорастворимых ингредиентов
US13/711,449 US20130108674A1 (en) 2010-06-11 2012-12-11 Ophthalmic compositions for the administration of liposoluble active ingredients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM2010A000322A IT1404931B1 (it) 2010-06-11 2010-06-11 Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .

Publications (2)

Publication Number Publication Date
ITRM20100322A1 ITRM20100322A1 (it) 2011-12-12
IT1404931B1 true IT1404931B1 (it) 2013-12-09

Family

ID=43740390

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM2010A000322A IT1404931B1 (it) 2010-06-11 2010-06-11 Composizioni oftalmiche per la somministrazione di principi attivi liposolubili .

Country Status (8)

Country Link
US (1) US20130108674A1 (it)
EP (1) EP2579845B1 (it)
CN (1) CN103079543A (it)
CA (1) CA2802162A1 (it)
IT (1) IT1404931B1 (it)
MX (1) MX2012014443A (it)
RU (1) RU2013100984A (it)
WO (1) WO2011154985A1 (it)

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WO2013179253A1 (en) * 2012-06-02 2013-12-05 Micro Labs Limited Dose combination comprising nsaid and steroidal anti-inflammatory agent for treating post operative ocular inflammation
GB201222455D0 (en) * 2012-12-13 2013-01-30 Perioc Ltd Novel pharmaceutical formulations and their use in the treatment of periodontaldisease
AU2016226224B2 (en) * 2015-03-05 2021-07-08 Allergan, Inc. Self-emulsifying drug delivery system (SEDDS) for ophthalmic drug delivery
KR101635915B1 (ko) * 2016-02-15 2016-07-04 삼천당제약주식회사 사이클로스포린과 히알루론산 또는 이의 염을 포함하는 수용액 형태의 안과용 조성물
ITUA20162425A1 (it) * 2016-04-08 2017-10-08 Medivis S R L Composizione oftalmica che comprende PVP-I
GB2550346B (en) * 2016-05-13 2021-02-24 Phytoceutical Ltd Micelles
PT3266446T (pt) * 2016-07-07 2019-01-30 Salvat Lab Sa Composição oftálmica compreendendo óleo de rícino e triglicérido de cadeia média
US20200352987A1 (en) * 2017-08-30 2020-11-12 Tathagata DUTTA Emulsions for ophthalmic delivery of antioxidants
DK3673896T3 (da) * 2018-12-28 2022-02-07 Dr Rolf Lambert Pharma Consulting Gmbh Liposomal øjendråbeopløsning og anvendelser deraf til behandling af tørre øjne.
CN114245737A (zh) 2019-06-11 2022-03-25 司斐股份有限公司 微乳剂组合物
CN110237233B (zh) * 2019-07-30 2021-01-15 沈阳兴齐眼药股份有限公司 一种含有环孢素的眼用药物组合物、其制备方法及用途
WO2021119822A1 (en) * 2019-12-18 2021-06-24 National Research Council Of Canada Emulsions of bioactive lipophilic compounds including oils
IT202000015583A1 (it) * 2020-06-30 2021-12-30 Iromed Group S R L Composizione oftalmica
IT202100006839A1 (it) * 2021-03-22 2022-09-22 Omisan Farm S R L Preparato topico oftalmico idrosolubile contenente luteina e relativo metodo di produzione
CN113750043A (zh) * 2021-09-18 2021-12-07 山东省药学科学院 一种塞来昔布自乳化口服液及其制备方法
DE102021212692A1 (de) * 2021-11-11 2023-05-11 Ursapharm Arzneimittel Gmbh Selbstemulgierende öl-in wasser-mikro- oder nanoemulsion so-wie emulgierende zusammensetzung
CN114601798B (zh) * 2022-03-23 2023-08-25 北京电子科技职业学院 含天然产物的眼用纳米脂肪乳及其制备方法和应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU614465B2 (en) 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
EP0708646A1 (en) 1994-05-06 1996-05-01 Alcon Laboratories, Inc. Use of vitamin e tocopheryl derivatives in ophthalmic compositions
JPH11505257A (ja) * 1995-05-19 1999-05-18 アボツト・ラボラトリーズ 親油性薬物の自己乳化性製剤
AU7719100A (en) * 1999-09-27 2001-04-30 Panayiotis Constantinides Compositions of tocol-soluble therapeutics
MEP89008A (en) * 2001-10-19 2011-12-20 Novel cyclosporin analog microemulsion preconcentrates
US20040185068A1 (en) * 2003-03-18 2004-09-23 Zhi-Jian Yu Self-emulsifying compositions, methods of use and preparation
ATE442146T1 (de) * 2003-11-07 2009-09-15 Senju Pharma Co Pharmazeutische zusammensetzung mit prostaglandin
WO2006050837A2 (en) 2004-11-09 2006-05-18 Novagali Pharma Sa Ophthalmic emulsions containing an immunosuppressive agent
CA2672973C (en) * 2006-12-21 2016-03-08 Novagali Pharma Sa Process for manufacturing ophthalmic oil-in-water emulsions
CN101918019B (zh) 2007-10-08 2014-11-26 奥里尼亚制药有限公司 包含钙调神经磷酸酶抑制剂或mTOR抑制剂的眼科组合物
WO2010045292A2 (en) * 2008-10-15 2010-04-22 The University Of North Carolina At Chapel Hill Nanoparticle compositions comprising liquid oil cores
JP2013511554A (ja) * 2009-11-23 2013-04-04 パラティン テクノロジーズ，インコーポレイテッド メラノコルチン−１受容体特異的線状ペプチド

Also Published As

Publication number Publication date
EP2579845A1 (en) 2013-04-17
ITRM20100322A1 (it) 2011-12-12
CA2802162A1 (en) 2011-12-15
WO2011154985A1 (en) 2011-12-15
RU2013100984A (ru) 2014-08-20
MX2012014443A (es) 2013-05-01
US20130108674A1 (en) 2013-05-02
EP2579845B1 (en) 2020-04-29
CN103079543A (zh) 2013-05-01

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