SMT201600243B - Composizioni farmaceutiche comprendenti anakinra senza citrato - Google Patents
Composizioni farmaceutiche comprendenti anakinra senza citratoInfo
- Publication number
- SMT201600243B SMT201600243B SM201600243T SM201600243T SMT201600243B SM T201600243 B SMT201600243 B SM T201600243B SM 201600243 T SM201600243 T SM 201600243T SM 201600243 T SM201600243 T SM 201600243T SM T201600243 B SMT201600243 B SM T201600243B
- Authority
- SM
- San Marino
- Prior art keywords
- citrate
- pharmaceutical compositions
- compositions including
- including anakinra
- anakinra
- Prior art date
Links
- HMLGSIZOMSVISS-ONJSNURVSA-N (7r)-7-[[(2z)-2-(2-amino-1,3-thiazol-4-yl)-2-(2,2-dimethylpropanoyloxymethoxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound N([C@@H]1C(N2C(=C(C=C)CSC21)C(O)=O)=O)C(=O)\C(=N/OCOC(=O)C(C)(C)C)C1=CSC(N)=N1 HMLGSIZOMSVISS-ONJSNURVSA-N 0.000 title 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 title 1
- 102000051628 Interleukin-1 receptor antagonist Human genes 0.000 title 1
- 108700021006 Interleukin-1 receptor antagonist Proteins 0.000 title 1
- 229960004238 anakinra Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/1793—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/545—IL-1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Dispersion Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1150109 | 2011-02-11 | ||
| PCT/SE2012/050124 WO2012108828A1 (en) | 2011-02-11 | 2012-02-09 | Citrate free pharmaceutical compositions comprising anakinra |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT201600243B true SMT201600243B (it) | 2016-08-31 |
Family
ID=46638837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM201600243T SMT201600243B (it) | 2011-02-11 | 2016-07-25 | Composizioni farmaceutiche comprendenti anakinra senza citrato |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US9198954B2 (it) |
| EP (1) | EP2672985B1 (it) |
| JP (1) | JP5937622B2 (it) |
| CN (1) | CN103347533B (it) |
| AU (1) | AU2012214879B2 (it) |
| BR (1) | BR112013020195B1 (it) |
| CA (1) | CA2824578A1 (it) |
| CY (1) | CY1117795T1 (it) |
| DK (1) | DK2672985T3 (it) |
| ES (1) | ES2582928T3 (it) |
| HR (1) | HRP20160928T1 (it) |
| HU (1) | HUE029809T2 (it) |
| LT (1) | LT2672985T (it) |
| PL (1) | PL2672985T3 (it) |
| PT (1) | PT2672985T (it) |
| RS (1) | RS54968B1 (it) |
| RU (1) | RU2599848C2 (it) |
| SI (1) | SI2672985T1 (it) |
| SM (1) | SMT201600243B (it) |
| WO (1) | WO2012108828A1 (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20160129112A1 (en) * | 2013-05-28 | 2016-05-12 | Momenta Pharmaceuticals, Inc. | Pharmaceutical Compositions Comprising Pyrophosphate |
| JP6769994B2 (ja) * | 2015-04-28 | 2020-10-14 | スウェディッシュ オーファン バイオビトラム アクティエボラーグ （ペーウーベーエル） | アナキンラを含む組成物 |
| PL3397270T3 (pl) | 2015-12-30 | 2024-08-19 | Green Cross Corporation | Kompozycje do zastosowania w leczeniu zespołu huntera |
| EP4326231A1 (en) * | 2021-04-22 | 2024-02-28 | Onspira Therapeutics, Inc. | Compositions of interleukin-1 receptor antagonist |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5075222A (en) | 1988-05-27 | 1991-12-24 | Synergen, Inc. | Interleukin-1 inhibitors |
| US6858409B1 (en) | 1988-05-27 | 2005-02-22 | Amgen Inc. | Nucleic acids encoding interleukin-1 inhibitors and processes for preparing interleukin-1 inhibitors |
| NZ256328A (en) * | 1992-09-17 | 1997-06-24 | Amgen Boulder Inc | Pharmaceutical compositions of interleukin-1 inhibitor and non-ionic surfactant or viscosity enhancer |
| US5656730A (en) * | 1995-04-07 | 1997-08-12 | Enzon, Inc. | Stabilized monomeric protein compositions |
| DE69739656D1 (de) * | 1996-02-09 | 2009-12-31 | Amgen Inc | 1 inhibitor und hyaluronan als polymer mit verzögerter wirkstofffreigabe |
| PT1729810T (pt) * | 2004-04-02 | 2018-11-22 | Swedish Orphan Biovitrum Ab Publ | Métodos de redução da agregação de il-ira |
| EP1948220A2 (en) * | 2005-10-21 | 2008-07-30 | Amgen Inc. | Methods of decreasing vascular calcification using il-1 inhibitors |
| WO2009015345A1 (en) * | 2007-07-25 | 2009-01-29 | Amgen Inc. | Pharmaceutical compositions comprising fc fusion proteins |
| CN101584857A (zh) * | 2008-05-23 | 2009-11-25 | 西藏诺迪康药业股份有限公司 | 一种眼用制剂及其制备方法 |
-
2012
- 2012-02-09 HR HRP20160928TT patent/HRP20160928T1/hr unknown
- 2012-02-09 ES ES12744410.7T patent/ES2582928T3/es active Active
- 2012-02-09 CA CA2824578A patent/CA2824578A1/en not_active Abandoned
- 2012-02-09 US US13/984,844 patent/US9198954B2/en active Active
- 2012-02-09 AU AU2012214879A patent/AU2012214879B2/en active Active
- 2012-02-09 SI SI201230618A patent/SI2672985T1/sl unknown
- 2012-02-09 DK DK12744410.7T patent/DK2672985T3/en active
- 2012-02-09 HU HUE12744410A patent/HUE029809T2/en unknown
- 2012-02-09 RS RS20160564A patent/RS54968B1/sr unknown
- 2012-02-09 WO PCT/SE2012/050124 patent/WO2012108828A1/en not_active Ceased
- 2012-02-09 PL PL12744410.7T patent/PL2672985T3/pl unknown
- 2012-02-09 LT LTEP12744410.7T patent/LT2672985T/lt unknown
- 2012-02-09 PT PT127444107T patent/PT2672985T/pt unknown
- 2012-02-09 BR BR112013020195-9A patent/BR112013020195B1/pt active IP Right Grant
- 2012-02-09 EP EP12744410.7A patent/EP2672985B1/en active Active
- 2012-02-09 CN CN201280008392.5A patent/CN103347533B/zh active Active
- 2012-02-09 RU RU2013141548/15A patent/RU2599848C2/ru active
- 2012-02-09 JP JP2013553397A patent/JP5937622B2/ja active Active
-
2015
- 2015-10-29 US US14/926,438 patent/US10179162B2/en active Active
-
2016
- 2016-07-18 CY CY20161100697T patent/CY1117795T1/el unknown
- 2016-07-25 SM SM201600243T patent/SMT201600243B/it unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2824578A1 (en) | 2012-08-16 |
| PL2672985T3 (pl) | 2016-11-30 |
| JP5937622B2 (ja) | 2016-06-22 |
| NZ613111A (en) | 2014-06-27 |
| HK1189355A1 (zh) | 2014-06-06 |
| CY1117795T1 (el) | 2017-05-17 |
| LT2672985T (lt) | 2016-10-10 |
| RU2013141548A (ru) | 2015-03-20 |
| US10179162B2 (en) | 2019-01-15 |
| US20140018298A1 (en) | 2014-01-16 |
| US20160045568A1 (en) | 2016-02-18 |
| RS54968B1 (sr) | 2016-11-30 |
| BR112013020195B1 (pt) | 2020-01-07 |
| WO2012108828A1 (en) | 2012-08-16 |
| CN103347533A (zh) | 2013-10-09 |
| HUE029809T2 (en) | 2017-03-28 |
| US9198954B2 (en) | 2015-12-01 |
| HRP20160928T1 (hr) | 2016-10-07 |
| EP2672985A4 (en) | 2014-07-30 |
| EP2672985B1 (en) | 2016-04-27 |
| DK2672985T3 (en) | 2016-06-27 |
| PT2672985T (pt) | 2016-07-25 |
| AU2012214879A1 (en) | 2013-07-25 |
| SI2672985T1 (sl) | 2016-09-30 |
| BR112013020195A2 (pt) | 2016-08-30 |
| ES2582928T3 (es) | 2016-09-16 |
| RU2599848C2 (ru) | 2016-10-20 |
| JP2014505099A (ja) | 2014-02-27 |
| EP2672985A1 (en) | 2013-12-18 |
| AU2012214879B2 (en) | 2016-05-19 |
| CN103347533B (zh) | 2015-12-23 |
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