ME00354B - Novi lekovi za tretiranje hronićnog opstruktivnog oboljenja pluća - Google Patents

Novi lekovi za tretiranje hronićnog opstruktivnog oboljenja pluća

Info

Publication number
ME00354B
ME00354B MEP-2008-536A MEP53608A ME00354B ME 00354 B ME00354 B ME 00354B ME P53608 A MEP53608 A ME P53608A ME 00354 B ME00354 B ME 00354B
Authority
ME
Montenegro
Prior art keywords
methyl
hydrogen
group
alkyl
general formula
Prior art date
Application number
MEP-2008-536A
Other languages
German (de)
English (en)
French (fr)
Unknown language (me)
Inventor
Klaus Rudolf
Philipp Lustenberger
Christoph Hoenke
Thierry Bouyssou
Frank Buettner
Ingo Konetzki
Sabine Pestel
Andreas Schnapp
Hermann Schollenberger
Kurt Schromm
Claudia Heine
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32185709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ME00354(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MEP53608A publication Critical patent/MEP53608A/xx
Publication of ME00354B publication Critical patent/ME00354B/me

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
MEP-2008-536A 2002-11-15 2003-11-11 Novi lekovi za tretiranje hronićnog opstruktivnog oboljenja pluća ME00354B (me)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (de) 2002-11-15 2002-11-15 Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
YU20050361A RS51607B (sr) 2002-11-15 2003-11-11 Novi lekovi za tretiranje hroničnog opstruktivnog oboljenja pluća
PCT/EP2003/012565 WO2004045618A2 (de) 2002-11-15 2003-11-11 Neue arzneimittel zur behandlung von chronisch obstruktiver lungenerkrankung

Publications (2)

Publication Number Publication Date
MEP53608A MEP53608A (en) 2011-05-10
ME00354B true ME00354B (me) 2011-10-10

Family

ID=32185709

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-2008-536A ME00354B (me) 2002-11-15 2003-11-11 Novi lekovi za tretiranje hronićnog opstruktivnog oboljenja pluća

Country Status (38)

Country Link
EP (2) EP1562603B3 (en:Method)
JP (1) JP4317138B2 (en:Method)
KR (1) KR101092247B1 (en:Method)
CN (3) CN101817800A (en:Method)
AR (2) AR041969A1 (en:Method)
AT (1) ATE430569T1 (en:Method)
AU (1) AU2003285326B2 (en:Method)
BE (1) BE2014C016I2 (en:Method)
BR (1) BRPI0316264B8 (en:Method)
CA (1) CA2506082C (en:Method)
CO (1) CO5570670A2 (en:Method)
CY (2) CY1110500T1 (en:Method)
DE (2) DE10253282A1 (en:Method)
DK (1) DK1562603T3 (en:Method)
EA (1) EA008665B1 (en:Method)
EC (1) ECSP055774A (en:Method)
ES (1) ES2326878T7 (en:Method)
FR (1) FR14C0049I2 (en:Method)
HR (1) HRP20050432B1 (en:Method)
HU (1) HUS1400011I1 (en:Method)
IL (1) IL167900A (en:Method)
LT (1) LTC1562603I2 (en:Method)
LU (1) LU92433I2 (en:Method)
ME (1) ME00354B (en:Method)
MX (1) MXPA05005081A (en:Method)
MY (1) MY136034A (en:Method)
NL (1) NL300650I2 (en:Method)
NO (2) NO334314B1 (en:Method)
NZ (1) NZ540661A (en:Method)
PE (1) PE20040694A1 (en:Method)
PL (1) PL212238B1 (en:Method)
PT (1) PT1562603E (en:Method)
RS (1) RS51607B (en:Method)
SI (1) SI1562603T1 (en:Method)
TW (1) TWI343812B (en:Method)
UA (1) UA81276C2 (en:Method)
WO (1) WO2004045618A2 (en:Method)
ZA (1) ZA200502246B (en:Method)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
ES2380370T3 (es) * 2004-04-22 2012-05-11 Boehringer Ingelheim International Gmbh Combinaciones farmacológicas que contienen benzoxazina para el tratamiento de enfermedades de las vías respiratorias
DE102004019539A1 (de) * 2004-04-22 2005-11-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittel zur Behandlung von Atemwegserkrankungen
JP2007537187A (ja) * 2004-05-13 2007-12-20 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 呼吸器疾患の治療においてβアゴニストとして使用するためのヒドロキシ置換ベンゾ縮合ヘテロ環化合物
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004024451A1 (de) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten
DE102004024452A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation von Betaagonisten
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
DE102004024453A1 (de) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Bronchodilatoren zur Behandlung von Atemwegserkrankungen
GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
DE102005007654A1 (de) * 2005-02-19 2006-08-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
BRPI0614290A2 (pt) 2005-08-08 2011-03-22 Argenta Discovery Ltd derivados de biciclo [ 2.2.1 ] hept-7-ilamina e seus usos
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
WO2007020227A1 (de) * 2005-08-15 2007-02-22 Boehringer Ingelheim International Gmbh Verfahren zur herstellung von betamimetika
US20070086957A1 (en) * 2005-10-10 2007-04-19 Thierry Bouyssou Combination of medicaments for the treatment of respiratory diseases
TWI389692B (zh) * 2005-10-10 2013-03-21 Boehringer Ingelheim Int 用以吸入β-共效劑的氣溶膠調配物
KR20080049113A (ko) 2005-10-21 2008-06-03 노파르티스 아게 Ｉｌ-13에 대항한 인간 항체 및 치료적 용도
CA2627726A1 (en) * 2005-11-09 2007-05-18 Boehringer Ingelheim International Gmbh Aerosolformulation for inhalation
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1986644A1 (de) * 2006-02-16 2008-11-05 Boehringer Ingelheim International GmbH Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
PE20080142A1 (es) 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion
CA2649215A1 (en) 2006-04-21 2007-11-01 Novartis Ag 2,6,9-trisubstituted purine compounds as adenosine aza receptor modulators
JP2010500319A (ja) * 2006-08-07 2010-01-07 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 鏡像体上純粋な新規ベータアゴニスト、それらの製造方法及び医薬としてのそれらの使用
UY30542A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de agonistas beta
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
KR20090073121A (ko) 2006-09-29 2009-07-02 노파르티스 아게 Ｐｉ3ｋ 지질 키나제 억제제로서의 피라졸로피리미딘
BRPI0718266A2 (pt) 2006-10-30 2014-01-07 Novartis Ag Compostos heterocíclicos como agentes anti-inflamatórios.
DK2104535T3 (da) 2007-01-10 2011-04-04 Irm Llc Forbindelser og sammensætninger som kanalaktiverende proteaseinhibitorer
ES2370952T3 (es) * 2007-01-25 2011-12-26 Boehringer Ingelheim International Gmbh Procedimiento para la preparación de betamiméticos.
DE602008005140D1 (de) 2007-05-07 2011-04-07 Novartis Ag Organische verbindungen
CA2707857C (en) 2007-12-10 2016-09-13 Novartis Ag Spirocyclic amiloride analogues
PT2231642E (pt) 2008-01-11 2014-03-12 Novartis Ag Pirimidinas como inibidores de quinase
ES2535736T3 (es) 2008-06-10 2015-05-14 Novartis Ag Derivados de pirazina como bloqueadores de los canales de sodio epitelial
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
DK2379507T3 (da) 2008-12-30 2014-01-27 Pulmagen Therapeutics Inflammation Ltd Sulfonamidforbindelser til behandling af åndedrætsforstyrrelser
US20110281917A1 (en) 2009-01-29 2011-11-17 Darrin Stuart Substituted Benzimidazoles for the Treatment of Astrocytomas
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
WO2011018454A1 (en) 2009-08-12 2011-02-17 Novartis Ag Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
IN2012DN01961A (en:Method) 2009-08-17 2015-08-21 Intellikine Llc
WO2011050325A1 (en) 2009-10-22 2011-04-28 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
GB0918924D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
UY33597A (es) 2010-09-09 2012-04-30 Irm Llc Compuestos y composiciones como inhibidores de la trk
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
JP6084926B2 (ja) * 2010-09-21 2017-02-22 インテクリン・セラピユーテイクス・インコーポレイテツド 抗糖尿病固体医薬組成物
WO2012107500A1 (en) 2011-02-10 2012-08-16 Novartis Ag [1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
WO2012116237A2 (en) 2011-02-23 2012-08-30 Intellikine, Llc Heterocyclic compounds and uses thereof
WO2012116217A1 (en) 2011-02-25 2012-08-30 Irm Llc Compounds and compositions as trk inhibitors
US8883819B2 (en) 2011-09-01 2014-11-11 Irm Llc Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension
US9062045B2 (en) 2011-09-15 2015-06-23 Novartis Ag Triazolopyridine compounds
JP6165733B2 (ja) 2011-09-16 2017-07-19 ノバルティス アーゲー Ｎ−置換ヘテロシクリルカルボキサミド類
CN103946221B (zh) 2011-09-16 2016-08-03 诺华股份有限公司 用于治疗囊性纤维化的杂环化合物
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013078440A2 (en) 2011-11-23 2013-05-30 Intellikine, Llc Enhanced treatment regimens using mtor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
MX371119B (es) 2012-04-03 2020-01-17 Novartis Ag Productos de combinacion con los inhibidores de cinasa de tirosina y su uso.
WO2014056840A1 (en) 2012-10-09 2014-04-17 Boehringer Ingelheim International Gmbh Beta-2-adrenoceptor agonist for the treatment of cough
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
WO2014151147A1 (en) 2013-03-15 2014-09-25 Intellikine, Llc Combination of kinase inhibitors and uses thereof
TW201605450A (zh) 2013-12-03 2016-02-16 諾華公司 Ｍｄｍ２抑制劑與ＢＲＡＦ抑制劑之組合及其用途
US10004732B2 (en) 2014-04-24 2018-06-26 Novartis Ag Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
BR112016023967A2 (pt) 2014-04-24 2017-08-15 Novartis Ag derivados de pirazina como inibidores de fosfatidilinositol 3-cinase
WO2015162456A1 (en) 2014-04-24 2015-10-29 Novartis Ag Amino pyridine derivatives as phosphatidylinositol 3-kinase inhibitors
WO2016011658A1 (en) 2014-07-25 2016-01-28 Novartis Ag Combination therapy
MX373272B (es) 2014-07-31 2020-04-16 Novartis Ag Terapia de combinacion.
WO2018108669A1 (en) 2016-12-12 2018-06-21 Boehringer Ingelheim International Gmbh Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with olodaterol
WO2018114887A1 (en) 2016-12-20 2018-06-28 Laboratorios Lesvi, S.L. Improved process for the manufacture of r-6-hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylaminoethyl]-2h-1,4-benzoxazin-3(4h)-one hydrochloride
CN109096218B (zh) * 2018-08-06 2020-10-27 上海方予健康医药科技有限公司 盐酸奥达特罗晶型a及其制备方法
CN108997248B (zh) * 2018-08-06 2023-08-01 上海方予健康医药科技有限公司 盐酸奥达特罗晶型b及其制备方法
WO2020250116A1 (en) 2019-06-10 2020-12-17 Novartis Ag Pyridine and pyrazine derivative for the treatment of cf, copd, and bronchiectasis
JP2022547427A (ja) 2019-08-28 2022-11-14 ノバルティス アーゲー 置換１，３－フェニルヘテロアリール誘導体及び疾患の治療におけるその使用
US11304897B2 (en) 2020-06-09 2022-04-19 Anovent Pharmaceutical (U.S.), Llc Pharmaceutical formulation containing umeclidinium bromide and vilanterol trifenatate
US11331322B1 (en) 2021-09-15 2022-05-17 Santen Pharmaceutical Co., Ltd. Medicament for preventing and/or treating dry eye

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134590A1 (de) * 1981-09-01 1983-03-10 Boehringer Ingelheim KG, 6507 Ingelheim Neue benzo-heterocyclen
US4460581A (en) * 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
DE3743265A1 (de) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg Neue ammoniumverbindungen, ihre herstellung und verwendung
KR20020093083A (ko) * 2000-04-27 2002-12-12 베링거 잉겔하임 파르마 카게 신규한 완효성 베타모사체, 이의 제조방법 및 약제로서의이의 용도

Also Published As

Publication number Publication date
CN1713914A (zh) 2005-12-28
FR14C0049I1 (en:Method) 2014-08-08
MY136034A (en) 2008-07-31
PL375270A1 (en) 2005-11-28
EP1562603B3 (de) 2014-01-08
CA2506082C (en) 2011-06-21
DE50311502D1 (de) 2009-06-18
MXPA05005081A (es) 2005-07-01
KR20050075013A (ko) 2005-07-19
NO20052883L (no) 2005-06-14
BRPI0316264B1 (pt) 2019-04-09
NO334314B1 (no) 2014-02-03
PL212238B1 (pl) 2012-08-31
NL300650I2 (nl) 2017-11-02
AR087241A2 (es) 2014-03-12
LTC1562603I2 (lt) 2016-12-12
WO2004045618A2 (de) 2004-06-03
ES2326878T3 (es) 2009-10-21
SI1562603T1 (sl) 2009-10-31
AU2003285326A1 (en) 2004-06-15
HRP20050432A2 (en) 2006-06-30
CY2014032I1 (el) 2015-12-09
CN101817800A (zh) 2010-09-01
UA81276C2 (en) 2007-12-25
BE2014C016I2 (en:Method) 2023-03-07
HUS1400011I1 (hu) 2022-02-28
CY2014032I2 (el) 2015-12-09
CY1110500T1 (el) 2015-04-29
TWI343812B (en) 2011-06-21
KR101092247B1 (ko) 2011-12-12
DE10253282A1 (de) 2004-05-27
BRPI0316264B8 (pt) 2021-05-25
BR0316264A (pt) 2005-10-11
JP2006508140A (ja) 2006-03-09
CO5570670A2 (es) 2005-10-31
PE20040694A1 (es) 2004-11-23
IL167900A (en) 2013-06-27
ATE430569T1 (de) 2009-05-15
JP4317138B2 (ja) 2009-08-19
HRP20050432B1 (en) 2012-01-31
DK1562603T3 (da) 2009-09-07
FR14C0049I2 (fr) 2015-07-24
CN101735166A (zh) 2010-06-16
EP1562603A2 (de) 2005-08-17
ES2326878T7 (es) 2014-03-11
EP1562603B1 (de) 2009-05-06
ECSP055774A (es) 2005-11-22
RS20050361A (sr) 2007-04-10
MEP53608A (en) 2011-05-10
TW200423943A (en) 2004-11-16
AR041969A1 (es) 2005-06-01
WO2004045618A3 (de) 2004-09-30
CA2506082A1 (en) 2004-06-03
NZ540661A (en) 2007-12-21
PT1562603E (pt) 2009-06-18
AU2003285326B2 (en) 2009-06-04
EA200500715A1 (ru) 2005-12-29
ZA200502246B (en) 2006-01-25
EP2025338A1 (de) 2009-02-18
LU92433I2 (fr) 2014-06-24
EA008665B1 (ru) 2007-06-29
NO2014005I1 (no) 2014-03-10
RS51607B (sr) 2011-08-31

Similar Documents

Publication Publication Date Title
ME00354B (me) Novi lekovi za tretiranje hronićnog opstruktivnog oboljenja pluća
WO2004037807A3 (en) Medicinal arylethanolamine compounds
RU2010108640A (ru) Новая комбинация терапевтических агентов
EA200300776A1 (ru) Производные фенэтаноламина для лечения респираторных заболеваний
DE60318193D1 (en) Phenethanolaminderivate
HUP0101999A2 (hu) 4-Hidroxi-kinolin-3-karboxamid- és -hidrazid-származékok, ezeket tartalmazó gyógyászati készítmények, valamint e vegyületek alkalmazása
MXPA03011638A (es) Nuevos derivados de 4-piperazinil indol con afinidad por el receptor 5-ht6.
MXPA04007414A (es) Indoles sustituidos como agonistas alfa-1.
CA2671470A1 (en) Powder formulation for valganciclovir
ATE216575T1 (de) Treibgasmischung für eine aerosolzubereitung
ATE330589T1 (de) Pharmazeutische zusammensetzung enthaltend resveratrol zur behandlung von entzündlichen erkrankungen der atemwege
NO20052130L (no) Sterk inhibitor for HCV-serin-protease
RU2472783C2 (ru) Аминные производные и их применение в бета-2-адренорецептор-опосредованных заболеваниях
RU2006132036A (ru) Комбинация и фармацевтический препарат для лечения аллергий и заболеваний дыхательных путей
MX2023010087A (es) Derivados heterociclicos como inhibidores de cinasas jano.
MX2007004740A (es) Derivados de 2-amido-4-feniltiazol, su preparacion y su aplicacion en terapeutica.
MY145166A (en) Novel tiotropium salts, process for the preparation and pharmaceutical compositions thereof
SE0101322D0 (sv) Novel compounds
MX2023010083A (es) Derivados heterociclicos como inhibidores de cinasas jano.
IL107654A0 (en) Use of dimethylbenzofurans and dimethylbenzopyrans as 5-ht3 antagonists certain such novel compounds their preparation and pharmaceutical compositions containing them
TW202539652A (zh) 化合物在製備預防和/或治療高原病的藥物中的應用
JPS58914A (ja) 抗ウイルス作用を有する医薬組成物
RU2662161C1 (ru) Ингибитор входа вируса гепатита и фармацевтическая композиция для лечения гепатита
CR20230331A (es) Derivados de pirazolamida
TH66454B (th) สารรักษาโรคชนิดใหม่เพื่อการรักษาโรคปอดที่เกิดภาวะอุดตันเรื้อรัง