MEP53608A - Novel medicaments for the treatment of chronic obstructive pulmonary diseases - Google Patents
Novel medicaments for the treatment of chronic obstructive pulmonary diseasesInfo
- Publication number
- MEP53608A MEP53608A MEP-536/08A MEP53608A MEP53608A ME P53608 A MEP53608 A ME P53608A ME P53608 A MEP53608 A ME P53608A ME P53608 A MEP53608 A ME P53608A
- Authority
- ME
- Montenegro
- Prior art keywords
- treatment
- chronic obstructive
- obstructive pulmonary
- pulmonary diseases
- novel medicaments
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
- C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
http://www.wipo.int/patentscope/search/en/docservice_fpimage/WOEP2003012565 false Pronalazak se odnosi na upotrebu jedinjenja opšte formule (I), u kojoj ostaci R1, R2 i R3 mogu da imaju značenja navedena u patentnim zahtjevima i u opisu, za pripremanje lijeka za tretiranje (liječenje) COPD-a (chronic obstructive pulmonary disease= hronično opstruktivno oboljenje pluća), kao i na nova jedinjenja opšte formule (I) kao takva.http://www.wipo.int/patentscope/search/en/docservice_fpimage/WOEP2003012565 false The invention relates to the use of compounds of general formula (I), in which the radicals R1, R2 and R3 can have the meanings given in the claims and in the description , for the preparation of a medicament for the treatment of COPD (chronic obstructive pulmonary disease), as well as novel compounds of general formula (I) as such.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10253282A DE10253282A1 (en) | 2002-11-15 | 2002-11-15 | Treatment of chronic obstructive pulmonary disease, using new or known N-substituted 2-amino-1-(benz-(1,4)-oxazin-3-on-8-yl)-ethanol derivative beta-mimetic agents, suitable for once-daily administration |
YU20050361A RS51607B (en) | 2002-11-15 | 2003-11-11 | Novel medicament for the treatment of chronic obstructive pulmonary diseases |
PCT/EP2003/012565 WO2004045618A2 (en) | 2002-11-15 | 2003-11-11 | Novel medicaments for the treatment of chronic obstructive pulmonary diseases |
Publications (2)
Publication Number | Publication Date |
---|---|
MEP53608A true MEP53608A (en) | 2011-05-10 |
ME00354B ME00354B (en) | 2011-10-10 |
Family
ID=32185709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MEP-2008-536A ME00354B (en) | 2002-11-15 | 2003-11-11 | Novel medicaments for the treatment of chronic obstructive pulmonary diseases |
Country Status (38)
Country | Link |
---|---|
EP (2) | EP2025338A1 (en) |
JP (1) | JP4317138B2 (en) |
KR (1) | KR101092247B1 (en) |
CN (3) | CN1713914A (en) |
AR (2) | AR041969A1 (en) |
AT (1) | ATE430569T1 (en) |
AU (1) | AU2003285326B2 (en) |
BE (1) | BE2014C016I2 (en) |
BR (1) | BRPI0316264B8 (en) |
CA (1) | CA2506082C (en) |
CO (1) | CO5570670A2 (en) |
CY (2) | CY1110500T1 (en) |
DE (2) | DE10253282A1 (en) |
DK (1) | DK1562603T3 (en) |
EA (1) | EA008665B1 (en) |
EC (1) | ECSP055774A (en) |
ES (1) | ES2326878T7 (en) |
FR (1) | FR14C0049I2 (en) |
HR (1) | HRP20050432B1 (en) |
HU (1) | HUS1400011I1 (en) |
IL (1) | IL167900A (en) |
LT (1) | LTC1562603I2 (en) |
LU (1) | LU92433I2 (en) |
ME (1) | ME00354B (en) |
MX (1) | MXPA05005081A (en) |
MY (1) | MY136034A (en) |
NL (1) | NL300650I2 (en) |
NO (2) | NO334314B1 (en) |
NZ (1) | NZ540661A (en) |
PE (1) | PE20040694A1 (en) |
PL (1) | PL212238B1 (en) |
PT (1) | PT1562603E (en) |
RS (1) | RS51607B (en) |
SI (1) | SI1562603T1 (en) |
TW (1) | TWI343812B (en) |
UA (1) | UA81276C2 (en) |
WO (1) | WO2004045618A2 (en) |
ZA (1) | ZA200502246B (en) |
Families Citing this family (92)
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US7056916B2 (en) | 2002-11-15 | 2006-06-06 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Medicaments for the treatment of chronic obstructive pulmonary disease |
GB0401334D0 (en) | 2004-01-21 | 2004-02-25 | Novartis Ag | Organic compounds |
ES2380370T3 (en) * | 2004-04-22 | 2012-05-11 | Boehringer Ingelheim International Gmbh | Pharmacological combinations containing benzoxazine for the treatment of respiratory diseases |
DE102004019539A1 (en) * | 2004-04-22 | 2005-11-10 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New drugs for the treatment of respiratory diseases |
JP2007537187A (en) * | 2004-05-13 | 2007-12-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Hydroxy-substituted benzofused heterocyclic compounds for use as beta agonists in the treatment of respiratory diseases |
DE102004024453A1 (en) * | 2004-05-14 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New long-acting bronchodilators for the treatment of respiratory diseases |
DE102004024452A1 (en) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosol formulation for the inhalation of beta agonists |
US20050256115A1 (en) * | 2004-05-14 | 2005-11-17 | Boehringer Ingelheim International Gmbh | Aerosol formulation for the inhalation of beta-agonists |
DE102004024454A1 (en) * | 2004-05-14 | 2005-12-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel enantiomerically pure beta agonists, process for their preparation and their use as pharmaceuticals |
DE102004024451A1 (en) * | 2004-05-14 | 2005-12-22 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder formulations for inhalation containing enantiomerically pure beta agonists |
US7745621B2 (en) | 2004-05-14 | 2010-06-29 | Boehringer Ingelheim International Gmbh | Long acting bronchodilators for the treatment of respiratory diseases |
US7220742B2 (en) | 2004-05-14 | 2007-05-22 | Boehringer Ingelheim International Gmbh | Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments |
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
DE102004045648A1 (en) * | 2004-09-21 | 2006-03-23 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New betamimetics for the treatment of respiratory diseases |
GT200500281A (en) | 2004-10-22 | 2006-04-24 | Novartis Ag | ORGANIC COMPOUNDS. |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
DE102005007654A1 (en) | 2005-02-19 | 2006-08-24 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New long-acting betamimetics for the treatment of respiratory diseases |
GB0507577D0 (en) | 2005-04-14 | 2005-05-18 | Novartis Ag | Organic compounds |
GB0510390D0 (en) | 2005-05-20 | 2005-06-29 | Novartis Ag | Organic compounds |
DE102005030733A1 (en) * | 2005-07-01 | 2007-01-04 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | New drug combinations for the treatment of respiratory diseases containing long-acting beta-2 agonists and at least one other active ingredient |
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KR20080036632A (en) | 2005-08-08 | 2008-04-28 | 아젠터 디스커버리 리미티드 | Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses |
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US20070086957A1 (en) * | 2005-10-10 | 2007-04-19 | Thierry Bouyssou | Combination of medicaments for the treatment of respiratory diseases |
US20070088030A1 (en) * | 2005-10-10 | 2007-04-19 | Barbara Niklaus-Humke | Aerosol formulations for the inhalation of beta-agonists |
CA2625664C (en) | 2005-10-21 | 2016-01-05 | Novartis Ag | Human antibodies against il13 and therapeutic uses |
AU2006311060A1 (en) * | 2005-11-09 | 2007-05-18 | Boehringer Ingelheim International Gmbh | Aerosolformulation for inhalation |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
JP2009526817A (en) * | 2006-02-16 | 2009-07-23 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Pharmaceutical composition for the treatment of respiratory diseases |
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PT2322525E (en) | 2006-04-21 | 2013-12-26 | Novartis Ag | Purine derivatives for use as adenosin a2a receptor agonists |
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UY30542A1 (en) * | 2006-08-18 | 2008-03-31 | Boehringer Ingelheim Int | AEROSOL FORMULATION FOR INHALATION OF BETA AGONISTS |
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ES2370952T3 (en) * | 2007-01-25 | 2011-12-26 | Boehringer Ingelheim International Gmbh | PROCEDURE FOR THE PREPARATION OF BETAMIMETICS. |
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UY33597A (en) | 2010-09-09 | 2012-04-30 | Irm Llc | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF THE TRK |
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ES2691650T3 (en) | 2011-09-15 | 2018-11-28 | Novartis Ag | 3- (quinolin-6-yl-thio) - [1,2,4] -triazolo- [4,3-a] -pyridines 6-substituted as inhibitors of tyrosine kinase c-Met |
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US8809340B2 (en) | 2012-03-19 | 2014-08-19 | Novartis Ag | Crystalline form |
RU2660354C2 (en) | 2012-04-03 | 2018-07-05 | Новартис Аг | Combined products containing tyrosine kinase inhibitors and their use |
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WO2018114887A1 (en) | 2016-12-20 | 2018-06-28 | Laboratorios Lesvi, S.L. | Improved process for the manufacture of r-6-hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylaminoethyl]-2h-1,4-benzoxazin-3(4h)-one hydrochloride |
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CN109096218B (en) * | 2018-08-06 | 2020-10-27 | 上海方予健康医药科技有限公司 | Oxydterol hydrochloride crystal form A and preparation method thereof |
CN113891744A (en) | 2019-06-10 | 2022-01-04 | 诺华股份有限公司 | Pyridine and pyrazine derivatives for the treatment of CF, COPD and bronchiectasis |
KR20220052934A (en) | 2019-08-28 | 2022-04-28 | 노파르티스 아게 | Substituted 1,3-phenyl heteroaryl derivatives and their use in the treatment of diseases |
WO2021252577A1 (en) * | 2020-06-09 | 2021-12-16 | Anovent Pharmaceutical (U.S.), Llc | Pharmaceutical formulation containing umeclidinium bromide and vilanterol trifenatate |
US11331322B1 (en) | 2021-09-15 | 2022-05-17 | Santen Pharmaceutical Co., Ltd. | Medicament for preventing and/or treating dry eye |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3134590A1 (en) * | 1981-09-01 | 1983-03-10 | Boehringer Ingelheim KG, 6507 Ingelheim | NEW BENZO HETEROCYCLES |
US4460581A (en) | 1982-10-12 | 1984-07-17 | Boehringer Ingelheim Kg | (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones |
DE3743265A1 (en) * | 1987-12-19 | 1989-06-29 | Boehringer Ingelheim Kg | NEW AMMONIUM COMPOUNDS, THEIR MANUFACTURE AND USE |
HUP0300832A2 (en) * | 2000-04-27 | 2003-08-28 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Novel, slow-acting betamimetics, a method for their production and their use as medicaments and pharmaceutical compositions containing them |
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2002
- 2002-11-15 DE DE10253282A patent/DE10253282A1/en not_active Withdrawn
-
2003
- 2003-11-11 WO PCT/EP2003/012565 patent/WO2004045618A2/en active Application Filing
- 2003-11-11 ES ES03778312.3T patent/ES2326878T7/en active Active
- 2003-11-11 CA CA2506082A patent/CA2506082C/en not_active Expired - Lifetime
- 2003-11-11 CN CNA2003801030945A patent/CN1713914A/en active Pending
- 2003-11-11 AT AT03778312T patent/ATE430569T1/en active
- 2003-11-11 PL PL375270A patent/PL212238B1/en unknown
- 2003-11-11 BR BRPI0316264A patent/BRPI0316264B8/en active IP Right Grant
- 2003-11-11 ME MEP-2008-536A patent/ME00354B/en unknown
- 2003-11-11 SI SI200331634T patent/SI1562603T1/en unknown
- 2003-11-11 MX MXPA05005081A patent/MXPA05005081A/en active IP Right Grant
- 2003-11-11 NZ NZ540661A patent/NZ540661A/en not_active IP Right Cessation
- 2003-11-11 UA UAA200505926A patent/UA81276C2/en unknown
- 2003-11-11 AU AU2003285326A patent/AU2003285326B2/en active Active
- 2003-11-11 JP JP2004552561A patent/JP4317138B2/en not_active Expired - Lifetime
- 2003-11-11 DE DE50311502T patent/DE50311502D1/en not_active Expired - Lifetime
- 2003-11-11 RS YU20050361A patent/RS51607B/en unknown
- 2003-11-11 PT PT03778312T patent/PT1562603E/en unknown
- 2003-11-11 EP EP08169872A patent/EP2025338A1/en not_active Withdrawn
- 2003-11-11 DK DK03778312T patent/DK1562603T3/en active
- 2003-11-11 KR KR1020057008679A patent/KR101092247B1/en active IP Right Grant
- 2003-11-11 CN CN201010004697A patent/CN101817800A/en active Pending
- 2003-11-11 CN CN200910266327A patent/CN101735166A/en active Pending
- 2003-11-11 EA EA200500715A patent/EA008665B1/en active Protection Beyond IP Right Term
- 2003-11-11 EP EP03778312.3A patent/EP1562603B3/en not_active Expired - Lifetime
- 2003-11-13 MY MYPI20034360A patent/MY136034A/en unknown
- 2003-11-13 PE PE2003001147A patent/PE20040694A1/en active IP Right Grant
- 2003-11-14 AR ARP030104201A patent/AR041969A1/en active Pending
- 2003-11-14 TW TW092132031A patent/TWI343812B/en active
-
2005
- 2005-03-17 ZA ZA2005/02246A patent/ZA200502246B/en unknown
- 2005-04-07 IL IL167900A patent/IL167900A/en active Protection Beyond IP Right Term
- 2005-05-02 EC EC2005005774A patent/ECSP055774A/en unknown
- 2005-05-13 HR HR20050432A patent/HRP20050432B1/en not_active IP Right Cessation
- 2005-06-14 NO NO20052883A patent/NO334314B1/en not_active IP Right Cessation
- 2005-06-14 CO CO05057641A patent/CO5570670A2/en not_active Application Discontinuation
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2009
- 2009-08-04 CY CY20091100826T patent/CY1110500T1/en unknown
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2012
- 2012-07-19 AR ARP120102613A patent/AR087241A2/en active Pending
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2014
- 2014-02-27 BE BE2014C016C patent/BE2014C016I2/fr unknown
- 2014-03-06 LT LTPA2014012C patent/LTC1562603I2/en unknown
- 2014-03-07 NL NL300650C patent/NL300650I2/en unknown
- 2014-03-07 HU HUS1400011C patent/HUS1400011I1/en unknown
- 2014-03-10 NO NO2014005C patent/NO2014005I1/en unknown
- 2014-04-22 LU LU92433C patent/LU92433I2/en unknown
- 2014-06-23 FR FR14C0049C patent/FR14C0049I2/en active Active
- 2014-08-13 CY CY2014032C patent/CY2014032I2/en unknown
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