MY136034A - New medicaments for the treatment of chronic obstructive pulmonary disease - Google Patents

New medicaments for the treatment of chronic obstructive pulmonary disease

Info

Publication number
MY136034A
MY136034A MYPI20034360A MYPI20034360A MY136034A MY 136034 A MY136034 A MY 136034A MY PI20034360 A MYPI20034360 A MY PI20034360A MY PI20034360 A MYPI20034360 A MY PI20034360A MY 136034 A MY136034 A MY 136034A
Authority
MY
Malaysia
Prior art keywords
treatment
pulmonary disease
chronic obstructive
obstructive pulmonary
new medicaments
Prior art date
Application number
MYPI20034360A
Inventor
Thierry Dr Bouyssou
Philipp Dr Lustenberger
Hoenke Dr Christoph
Frank Dr Buettner
Ingo Dr Konetzki
Sabine Dr Pestel
Andreas Dr Schnapp
Hermann Schollenberger
Kurt Dr Schromm
Claudia Dr Heine
Klaus Dr Rudolf
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
Priority to DE10253282A priority Critical patent/DE10253282A1/en
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of MY136034A publication Critical patent/MY136034A/en
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32185709&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MY136034(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/5381,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/341,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/361,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring

Abstract

THE PRESENT INVENTION RELATES TO THE USE OF THE COMPOUNDS OF GENERAL FORMULA WHEREIN THE GROUPS R1, R2 AND R3 MAY HAVE THE MEANINGS GIVEN IN THE CLAIMS AND IN THE SPECIFICATION, FOR PREPARING A PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF COPD (CHRONIC OBSTRUCTIVE PULMONARY DISEASE), AS WELL AS NEW COMPOUNDS OF GENERAL FORMULA 1 AS SUCH.
MYPI20034360A 2002-11-15 2003-11-13 New medicaments for the treatment of chronic obstructive pulmonary disease MY136034A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (en) 2002-11-15 2002-11-15 Treatment of chronic obstructive pulmonary disease, using new or known N-substituted 2-amino-1-(benz-(1,4)-oxazin-3-on-8-yl)-ethanol derivative beta-mimetic agents, suitable for once-daily administration

Publications (1)

Publication Number Publication Date
MY136034A true MY136034A (en) 2008-07-31

Family

ID=32185709

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20034360A MY136034A (en) 2002-11-15 2003-11-13 New medicaments for the treatment of chronic obstructive pulmonary disease

Country Status (34)

Country Link
EP (2) EP2025338A1 (en)
JP (1) JP4317138B2 (en)
KR (1) KR101092247B1 (en)
CN (3) CN101817800A (en)
AR (2) AR041969A1 (en)
AT (1) AT430569T (en)
AU (1) AU2003285326B2 (en)
BR (1) BR0316264A (en)
CA (1) CA2506082C (en)
CO (1) CO5570670A2 (en)
CY (1) CY1110500T1 (en)
DE (2) DE10253282A1 (en)
DK (1) DK1562603T3 (en)
EA (1) EA008665B1 (en)
EC (1) ECSP055774A (en)
ES (1) ES2326878T7 (en)
HR (1) HRP20050432B1 (en)
IL (1) IL167900A (en)
LT (1) LTC1562603I2 (en)
LU (1) LU92433I2 (en)
ME (1) ME00354B (en)
MX (1) MXPA05005081A (en)
MY (1) MY136034A (en)
NL (1) NL300650I2 (en)
NO (1) NO334314B1 (en)
NZ (1) NZ540661A (en)
PE (1) PE06942004A1 (en)
PL (1) PL212238B1 (en)
PT (1) PT1562603E (en)
RS (1) RS51607B (en)
TW (1) TWI343812B (en)
UA (1) UA81276C2 (en)
WO (1) WO2004045618A2 (en)
ZA (1) ZA200502246B (en)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7056916B2 (en) 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
GB0401334D0 (en) 2004-01-21 2004-02-25 Novartis Ag Organic compounds
DE102004019539A1 (en) * 2004-04-22 2005-11-10 Boehringer Ingelheim Pharma Gmbh & Co. Kg New drugs for the treatment of respiratory diseases
SG152237A1 (en) * 2004-04-22 2009-05-29 Boehringer Ingelheim Int Pharmaceutical combinations containing benzoxazine for treating respiratory diseases
EP1789394A1 (en) * 2004-05-13 2007-05-30 Boehringer Ingelheim International Gmbh Hydroxy-substituted benzo-condensed heterocycles for use as beta agonists in the treatment of respiratory diseases
US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
DE102004024453A1 (en) * 2004-05-14 2006-01-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg New long-acting bronchodilators for the treatment of respiratory diseases
DE102004024451A1 (en) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder formulations for inhalation which contain Enantiomerically pure beta agonists
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
DE102004024452A1 (en) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosol formulation for inhalation of beta agonists
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
DE102004024454A1 (en) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg New Enantiomerically pure beta-agonists, to processes for their preparation and their use as medicaments
DE102004045648A1 (en) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg New betamimetics for the treatment of respiratory diseases
GT200500281A (en) 2004-10-22 2006-04-24 Novartis Ag organic compounds.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
DE102005007654A1 (en) 2005-02-19 2006-08-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg New long-acting beta-mimetics for the treatment of respiratory diseases
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
DE102005030733A1 (en) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg New drug combinations for the treatment of respiratory diseases including long-acting beta-2 agonist and at least one other active substance
GB0516313D0 (en) 2005-08-08 2005-09-14 Argenta Discovery Ltd Azole derivatives and their uses
EP1924553A1 (en) 2005-08-08 2008-05-28 Argenta Discovery Limited Bicyclo[2.2.]hept-7-ylamine derivatives and their uses
KR101360803B1 (en) 2005-08-15 2014-02-11 베링거 인겔하임 인터내셔날 게엠베하 Method for producing betamimetics
US20070088030A1 (en) * 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
TWI396541B (en) 2005-10-10 2013-05-21 Boehringer Ingelheim Int Novel combinations of medicaments for the treatment of respiratory diseases
PL2532679T3 (en) 2005-10-21 2017-09-29 Novartis Ag Human antibodies against il13 and therapeutic uses
AU2006311060A1 (en) * 2005-11-09 2007-05-18 Boehringer Ingelheim International Gmbh Aerosolformulation for inhalation
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
CA2642239A1 (en) * 2006-02-16 2007-08-23 Boehringer Ingelheim International Gmbh Drug combinations for the treatment of respiratory tract diseases
PE01422008A1 (en) * 2006-03-15 2008-04-14 Boehringer Ingelheim Int Enantiomerically pure beta-agonists and their methods of preparation
RU2457209C2 (en) 2006-04-21 2012-07-27 Новартис Аг Purine derivatives applicable as adenosine receptor a2a agonists
WO2008017638A1 (en) * 2006-08-07 2008-02-14 Boehringer Ingelheim International Gmbh Single enantiomer beta-agonists, methods for the production thereof and the use thereof as medication
UY30542A1 (en) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Aerosol formulation for inhalation of beta agonists
UY30543A1 (en) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Aerosol formulation for inhalation of beta agonists
AU2007302263A1 (en) 2006-09-29 2008-04-03 Novartis Ag Pyrazolopyrimidines as P13K lipid kinase inhibitors
AU2007315234A1 (en) 2006-10-30 2008-05-08 Novartis Ag Heterocyclic compounds as antiinflammatory agents
DK2104535T3 (en) 2007-01-10 2011-04-04 Irm Llc Compounds and compositions as channel activating protease inhibitors
AU2008208813B2 (en) * 2007-01-25 2013-05-09 Boehringer Ingelheim International Gmbh Method for producing betamimetics
CN101687851B (en) 2007-05-07 2013-02-27 诺瓦提斯公司 Organic compounds
MX2010006421A (en) 2007-12-10 2010-06-25 Novartis Ag Organic compounds.
WO2009087224A1 (en) 2008-01-11 2009-07-16 Novartis Ag Pyrimidines as kinase inhibitors
ES2535736T3 (en) 2008-06-10 2015-05-14 Novartis Ag Pyrazine derivatives as blockers of epithelial sodium channels
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
DK2379507T3 (en) 2008-12-30 2014-01-27 Pulmagen Therapeutics Inflammation Ltd Sulfonamide compounds for the treatment of respiratory disorders
JP2012516345A (en) 2009-01-29 2012-07-19 ノバルティス アーゲー Astrocytoma Therapeutic substituted benzimidazole
WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
KR20120089643A (en) 2009-08-12 2012-08-13 노파르티스 아게 Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
GEP201706639B (en) 2009-08-17 2017-03-27 Intellikine Llc Heterocyclic compounds and uses thereof
WO2011050325A1 (en) 2009-10-22 2011-04-28 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
GB0918924D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Azaindole derivatives
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
CA2811634C (en) * 2010-09-21 2019-01-15 Intekrin Therapeutics, Inc. Antidiabetic solid pharmaceutical compositions
US20130324526A1 (en) 2011-02-10 2013-12-05 Novartis Ag [1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
US9127000B2 (en) 2011-02-23 2015-09-08 Intellikine, LLC. Heterocyclic compounds and uses thereof
BR112013021638A2 (en) 2011-02-25 2016-08-02 Irm Llc "Trk inhibitor compounds, their use and compositions comprising"
UY34305A (en) 2011-09-01 2013-04-30 Novartis Ag Derivatives bicyclic heterocycles for treating pulmonary arterial hypertension
BR112014006223A8 (en) 2011-09-15 2018-01-09 Novartis Ag 3- (quinolin-6-ylthio) - [1,2,4-triazolo [4,3-a] piradinas 6-substituted, their uses, pharmaceutical compositions, and combination
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038390A1 (en) 2011-09-16 2013-03-21 Novartis Ag N-substituted heterocyclyl carboxamides
US9034879B2 (en) 2011-09-16 2015-05-19 Novartis Ag Heterocyclic compounds for the treatment of CF
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
CA2856803A1 (en) 2011-11-23 2013-05-30 Intellikine, Llc Enhanced treatment regimens using mtor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
KR20150001782A (en) 2012-04-03 2015-01-06 노파르티스 아게 Combination products with tyrosine kinase inhibitors and their use
WO2014056840A1 (en) 2012-10-09 2014-04-17 Boehringer Ingelheim International Gmbh Beta-2-adrenoceptor agonist for the treatment of cough
US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
WO2015084804A1 (en) 2013-12-03 2015-06-11 Novartis Ag Combination of mdm2 inhibitor and braf inhibitor and their use
KR20160141855A (en) 2014-04-24 2016-12-09 노파르티스 아게 Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
JP6404944B2 (en) 2014-04-24 2018-10-17 ノバルティス アーゲー Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitor
JP6454727B2 (en) 2014-04-24 2019-01-16 ノバルティス アーゲー Aminopyridine derivatives as phosphatidylinositol 3-kinase inhibitor
RU2017105827A3 (en) 2014-07-31 2019-03-04
WO2018108669A1 (en) 2016-12-12 2018-06-21 Boehringer Ingelheim International Gmbh Nintedanib for use in methods for the treatment of interstitial lung diseases by coadministration with olodaterol
WO2018114887A1 (en) 2016-12-20 2018-06-28 Laboratorios Lesvi, S.L. Improved process for the manufacture of r-6-hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylaminoethyl]-2h-1,4-benzoxazin-3(4h)-one hydrochloride

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3134590A1 (en) * 1981-09-01 1983-03-10 Boehringer Ingelheim Kg New benzo-heterocycles
US4460581A (en) 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
DE3743265A1 (en) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg New ammonium compounds, their production and use
NZ522677A (en) * 2000-04-27 2004-10-29 Boehringer Ingelheim Pharma Novel, slow-acting betamimetics, a method for their production and their use as medicaments

Also Published As

Publication number Publication date
EP1562603B1 (en) 2009-05-06
MEP53608A (en) 2011-05-10
EP1562603B3 (en) 2014-01-08
TW200423943A (en) 2004-11-16
CN1713914A (en) 2005-12-28
CA2506082A1 (en) 2004-06-03
AU2003285326A1 (en) 2004-06-15
IL167900A (en) 2013-06-27
RS51607B (en) 2011-08-31
NZ540661A (en) 2007-12-21
CO5570670A2 (en) 2005-10-31
JP4317138B2 (en) 2009-08-19
HRP20050432A2 (en) 2006-06-30
NL300650I2 (en) 2017-11-02
NO334314B1 (en) 2014-02-03
CY1110500T1 (en) 2015-04-29
PL212238B1 (en) 2012-08-31
WO2004045618A3 (en) 2004-09-30
TWI343812B (en) 2011-06-21
LTC1562603I2 (en) 2016-12-12
PL375270A1 (en) 2005-11-28
SI1562603T1 (en) 2009-10-31
DE50311502D1 (en) 2009-06-18
BR0316264A (en) 2005-10-11
AT430569T (en) 2009-05-15
MXPA05005081A (en) 2005-07-01
RS20050361A (en) 2007-04-10
AR041969A1 (en) 2005-06-01
AU2003285326B2 (en) 2009-06-04
KR101092247B1 (en) 2011-12-12
ECSP055774A (en) 2005-11-22
ES2326878T3 (en) 2009-10-21
KR20050075013A (en) 2005-07-19
ZA200502246B (en) 2006-01-25
DE10253282A1 (en) 2004-05-27
ME00354B (en) 2011-10-10
CN101735166A (en) 2010-06-16
EA200500715A1 (en) 2005-12-29
CN101817800A (en) 2010-09-01
EA008665B1 (en) 2007-06-29
LU92433I2 (en) 2014-06-24
HRP20050432B1 (en) 2012-01-31
DK1562603T3 (en) 2009-09-07
CA2506082C (en) 2011-06-21
PT1562603E (en) 2009-06-18
EP2025338A1 (en) 2009-02-18
PE06942004A1 (en) 2004-11-23
JP2006508140A (en) 2006-03-09
ES2326878T7 (en) 2014-03-11
AR087241A2 (en) 2014-03-12
UA81276C2 (en) 2007-12-25
NO20052883A (en) 2005-06-14
EP1562603A2 (en) 2005-08-17
WO2004045618A2 (en) 2004-06-03

Similar Documents

Publication Publication Date Title
TWI274754B (en) Purine derivatives, pharmaceutical composition for the treatment of a condition mediated by SYK kinase comprising the same and process for the preparation thereof
JO2371B1 (en) 4-phenyl -pyridine derivatives
TWI283665B (en) Novel urea compound, pharmaceutical composition containing the same and its use
WO2004037773A8 (en) Phenethanolamine derivative for the treatment of respiratory diseases
TW200619218A (en) Pyrimidines as PLK inhibitors
NZ570973A (en) Pyrazole-amide-adamantane derivatives as 11-beta-HSD-1 inhibitors
MX2007014619A (en) Pyrrolopyridines useful as inhibitors of protein kinase.
TW200400933A (en) Medicinal compounds
WO2004078747A8 (en) Novel cyanopyridine derivatives useful in the treatment of cancer and other disorders
WO2004037807A3 (en) Medicinal arylethanolamine compounds
WO2004037768A3 (en) Phenethanolamine derivatives
MXPA03011484A (en) Quinuclidines-substituted-multi-cyclic-heteroaryls for the treatment of disease.
MY142029A (en) Phenoxyacetic acid derivatives
TW200303750A (en) Organic compounds
WO2004014322A3 (en) Immunomodulatory compositions, methods of making, and methods of use thereof
MY137039A (en) Thiophene glycoside derivatives, processes for the preparation, medicaments comprising these compounds, and the use thereof
MXPA02011311A (en) Novel composition.
JO2353B1 (en) Novel heterocyclic fluoroglycoside derivatives, medicaments containing these compounds, and the use thereof
TW200413332A (en) New carboxamide compounds having MCH-antagonistic activity, pharmaceutical preparations comprising these compounds and process for their manufacture
CA2555331A1 (en) Therapeutic agents
WO2003053330A3 (en) Use of oxindole derivatives in the treatment of dementia related diseases, alzheimer’s disease and conditions associated with glycogen synthase kinase-3
MX2009006742A (en) Novel compounds.
BG108650A (en) Azabicyclic-substituted fused-heteroaryl compounds for the treatment of disease
MXPA02011400A (en) Arylmethylamine derivatives for use as tryptase inhibitors.
CA2636826A1 (en) Thiazoles as 11 beta-hsd1 inhibitors