ATE216575T1 - Treibgasmischung für eine aerosolzubereitung - Google Patents

Treibgasmischung für eine aerosolzubereitung

Info

Publication number
ATE216575T1
ATE216575T1 AT95941077T AT95941077T ATE216575T1 AT E216575 T1 ATE216575 T1 AT E216575T1 AT 95941077 T AT95941077 T AT 95941077T AT 95941077 T AT95941077 T AT 95941077T AT E216575 T1 ATE216575 T1 AT E216575T1
Authority
AT
Austria
Prior art keywords
gas mixture
propellant gas
aerosol preparation
propellant
inhalation
Prior art date
Application number
AT95941077T
Other languages
English (en)
Inventor
Andrew Sapsford
Andrew Patrick Savage
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of ATE216575T1 publication Critical patent/ATE216575T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K3/00—Materials not provided for elsewhere
    • C09K3/30—Materials not provided for elsewhere for aerosols

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Materials Engineering (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
AT95941077T 1994-12-10 1995-12-08 Treibgasmischung für eine aerosolzubereitung ATE216575T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9425160.0A GB9425160D0 (en) 1994-12-10 1994-12-10 Medicaments
PCT/EP1995/004824 WO1996018384A1 (en) 1994-12-10 1995-12-08 Propellant mixture for aerosol formulation

Publications (1)

Publication Number Publication Date
ATE216575T1 true ATE216575T1 (de) 2002-05-15

Family

ID=10765889

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95941077T ATE216575T1 (de) 1994-12-10 1995-12-08 Treibgasmischung für eine aerosolzubereitung

Country Status (9)

Country Link
US (2) US6153173A (de)
EP (1) EP0789557B1 (de)
JP (1) JPH10510521A (de)
AT (1) ATE216575T1 (de)
AU (1) AU4260496A (de)
DE (1) DE69526517T2 (de)
ES (1) ES2174970T3 (de)
GB (1) GB9425160D0 (de)
WO (1) WO1996018384A1 (de)

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DE4003270A1 (de) * 1990-02-03 1991-08-08 Boehringer Ingelheim Kg Neue treibgase und ihre verwendung in arzneimittelzubereitungen
CA2125143A1 (en) * 1991-12-03 1993-06-10 Cynthia L. Gage Refrigerant compositions and processes for using same
US20030103907A1 (en) * 1991-12-18 2003-06-05 Schultz Robert K. Suspension aerosol formulations
US7105152B1 (en) 1991-12-18 2006-09-12 3M Innovative Properties Company Suspension aerosol formulations
US7101534B1 (en) 1991-12-18 2006-09-05 3M Innovative Properties Company Suspension aerosol formulations
AU675633B2 (en) * 1991-12-18 1997-02-13 Minnesota Mining And Manufacturing Company Suspension aerosol formulations
CN1088580C (zh) * 1994-12-22 2002-08-07 阿斯特拉公司 气溶胶药物制剂
US6054488A (en) * 1996-06-11 2000-04-25 3M Innovative Properties Company Medicinal aerosol formulations of formoterol
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GB9616237D0 (en) 1996-08-01 1996-09-11 Norton Healthcare Ltd Aerosol formulations
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide
GB9620187D0 (en) † 1996-09-27 1996-11-13 Minnesota Mining & Mfg Medicinal aerosol formulations
AU6181098A (en) * 1997-02-24 1998-09-09 Allied-Signal Inc. Azeotrope-like compositions of pentafluoropropane and tetrafluoroethane
US20010031244A1 (en) 1997-06-13 2001-10-18 Chiesi Farmaceutici S.P.A. Pharmaceutical aerosol composition
GB2332372B (en) * 1997-12-08 2002-08-14 Minnesota Mining & Mfg Pharmaceutical aerosol compositions
US6598603B1 (en) * 1997-12-31 2003-07-29 Astra Aktiebolag Method for treating respiratory diseases
US6086376A (en) * 1998-01-30 2000-07-11 Rtp Pharma Inc. Dry aerosol suspension of phospholipid-stabilized drug microparticles in a hydrofluoroalkane propellant
US6423298B2 (en) 1998-06-18 2002-07-23 Boehringer Ingelheim Pharmaceuticals, Inc. Pharmaceutical formulations for aerosols with two or more active substances
US6458338B1 (en) * 1998-09-22 2002-10-01 Aeropharm Technology Incorporated Amino acid stabilized medicinal aerosol formulations
US6235265B1 (en) 1998-10-28 2001-05-22 Alliedsignal Inc. Evaporative coolant for topical anesthesia comprising hydrofluorocarbons and/or hydrochlorofluorocarbons
DZ2947A1 (fr) 1998-11-25 2004-03-15 Chiesi Farma Spa Inhalateur à compteur de dose sous pression.
ES2193069T3 (es) * 1999-04-14 2003-11-01 Glaxo Group Ltd Formulacion farmaceutica en aerosol.
IT1313553B1 (it) 1999-07-23 2002-09-09 Chiesi Farma Spa Formulazioni ottimizzate costituite da soluzioni di steroidi dasomministrare per inalazione.
GB9918626D0 (en) * 1999-08-07 1999-10-13 Glaxo Group Ltd Valve
IT1317846B1 (it) 2000-02-22 2003-07-15 Chiesi Farma Spa Formulazioni contenenti un farmaco anticolinergico per il trattamentodella broncopneumopatia cronica ostruttiva.
DE60035904T2 (de) * 2000-05-11 2008-05-08 Alliedsignal Inc. Fluorkohlenwasserstoffe enthaltender verdampfungskühler
AU5070100A (en) 2000-05-22 2001-12-03 Chiesi Farma Spa Stable pharmaceutical solution formulations for pressurised metered dose inhalers
PT1372608E (pt) * 2001-03-30 2008-01-04 Jagotec Ag Formulações de aerossol médicas
US6667344B2 (en) 2001-04-17 2003-12-23 Dey, L.P. Bronchodilating compositions and methods
US20030055026A1 (en) 2001-04-17 2003-03-20 Dey L.P. Formoterol/steroid bronchodilating compositions and methods of use thereof
US6455028B1 (en) 2001-04-23 2002-09-24 Pharmascience Ipratropium formulation for pulmonary inhalation
EP1273292B1 (de) 2001-07-02 2004-05-26 CHIESI FARMACEUTICI S.p.A. Optimierte Tobramycin-Formulierung zur Aerosolbildung
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
US20030060422A1 (en) 2001-08-31 2003-03-27 Balaji Venkataraman Tannate compositions and methods of treatment
US20030191151A1 (en) * 2001-10-26 2003-10-09 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US6702997B2 (en) 2001-10-26 2004-03-09 Dey, L.P. Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
US20030140920A1 (en) * 2001-10-26 2003-07-31 Dey L.P. Albuterol inhalation soultion, system, kit and method for relieving symptoms of pediatric asthma
JP2003221335A (ja) 2001-10-26 2003-08-05 Dey Lp 慢性閉塞性肺疾患の症状を緩和するためのアルブテロールおよびイプラトロピウム吸入溶液、システム、キットおよび方法
US20030203930A1 (en) * 2001-10-26 2003-10-30 Imtiaz Chaudry Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
US7582284B2 (en) 2002-04-17 2009-09-01 Nektar Therapeutics Particulate materials
JP4933046B2 (ja) * 2002-09-06 2012-05-16 フィリップ モーリス ユーエスエー インコーポレイテッド 液体エアロゾル製剤、エアロゾル発生装置およびエアロゾル発生方法
WO2004022243A1 (en) 2002-09-06 2004-03-18 Chrysalis Technologies Incorporated Aerosol generating devices and methods for generating aerosols having controlled particle sizes
WO2004060260A2 (en) * 2002-12-18 2004-07-22 Glaxo Group Limited Drug delivery system with vented mouthpiece
US20040223918A1 (en) * 2003-05-07 2004-11-11 Chrysalis Technologies Incorporated Aerosolization of cromolyn sodium using a capillary aerosol generator
TWI359675B (en) 2003-07-10 2012-03-11 Dey L P Bronchodilating β-agonist compositions
EP1595531A1 (de) 2004-05-13 2005-11-16 CHIESI FARMACEUTICI S.p.A. Stabile Arzneimittellösung für Druckdosierinhalatoren
US20050238632A1 (en) * 2004-04-23 2005-10-27 Alburty David S Propellant formulations
US20060078506A1 (en) * 2004-05-20 2006-04-13 Ralph Niven Methods, systems and devices for noninvasive pulmonary delivery
US8028697B2 (en) 2005-04-28 2011-10-04 Trudell Medical International Ventilator circuit and method for the use thereof
US20070039635A1 (en) * 2005-08-19 2007-02-22 Honeywell International Inc. Gas jet apparatus and method
CA2677838C (en) 2007-02-11 2017-08-01 Map Pharmaceuticals, Inc. Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
HRP20160258T1 (hr) 2008-03-17 2016-04-22 Discovery Laboratories, Inc. Adapter za cijevni sustav ventilacije i proksimalni sustav za dovođenje aerosola
ES2402241T3 (es) 2008-10-22 2013-04-30 Trudell Medical International Sistema de suministro de aerosol modular
CN111297802A (zh) * 2018-12-12 2020-06-19 成都一平医药科技发展有限公司 一种用于抗炎及抗菌的组合物

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118494A (en) * 1990-03-23 1992-06-02 Minnesota Mining And Manufacturing Company Use of soluble fluorosurfactants for the preparation of metered-dose aerosol formulations
ES2071306T3 (es) * 1990-03-23 1995-06-16 Minnesota Mining & Mfg El uso de tensioactivos fluorados solubles para la preparacion de formulaciones aerosoles dosificadas.
US5474759A (en) * 1991-06-10 1995-12-12 Schering Corporation Non-chlorofluorocarbon aerosol formulations
ES2078056T3 (es) * 1991-07-22 1995-12-01 Du Pont Utilizacion de 1,2,2,3,3-pentafluoropropano.
US5674471A (en) * 1991-12-12 1997-10-07 Glaxo Group Limited Aerosol formulations containing P134a and salbutamol
IL104068A (en) * 1991-12-12 1998-10-30 Glaxo Group Ltd Surfactant-free pharmaceutical aerosol formulation comprising 1,1,1,2-tetrafluoroethane or 1,1,1,2,3,3,3-heptafluoro-n- propane as propellant
DE69205177T2 (de) * 1991-12-12 1996-03-21 Glaxo Group Ltd., Greenford, Middlesex Pharmazeutische Aerosolformulierung.
DE4230876A1 (de) * 1992-03-17 1993-09-23 Asta Medica Ag Druckgaspackungen unter verwendung von polyoxyethylen-glyceryl-oleaten
US5376359A (en) * 1992-07-07 1994-12-27 Glaxo, Inc. Method of stabilizing aerosol formulations
MX9304585A (es) * 1992-07-31 1994-03-31 Glaxo Group Ltd Formulacion farmaceutica en aerosol, lata adecuada para liberar la formulacion e inhalador de dosis dosificada que comprende la lata.
US5278196A (en) * 1993-03-25 1994-01-11 Great Lakes Chemical Corp. Hydrofluorocarbon compositions as blowing agents for cellular plastics
DE69424181T2 (de) * 1993-12-20 2000-10-19 Minnesota Mining And Mfg. Co., Saint Paul Flunisolide aerosolformulierungen
US6039932A (en) * 1996-09-27 2000-03-21 3M Innovative Properties Company Medicinal inhalation aerosol formulations containing budesonide

Also Published As

Publication number Publication date
DE69526517D1 (de) 2002-05-29
ES2174970T3 (es) 2002-11-16
WO1996018384A1 (en) 1996-06-20
JPH10510521A (ja) 1998-10-13
EP0789557B1 (de) 2002-04-24
US6309624B1 (en) 2001-10-30
US6153173A (en) 2000-11-28
EP0789557A1 (de) 1997-08-20
DE69526517T2 (de) 2002-10-31
AU4260496A (en) 1996-07-03
GB9425160D0 (en) 1995-02-08

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Legal Events

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