MC1969A1 - Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation - Google Patents
Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparationInfo
- Publication number
- MC1969A1 MC1969A1 MC882000A MC2000A MC1969A1 MC 1969 A1 MC1969 A1 MC 1969A1 MC 882000 A MC882000 A MC 882000A MC 2000 A MC2000 A MC 2000A MC 1969 A1 MC1969 A1 MC 1969A1
- Authority
- MC
- Monaco
- Prior art keywords
- compounds
- pharmacy
- medicine
- preparation
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB878719368A GB8719368D0 (en) | 1987-08-15 | 1987-08-15 | Heterocyclic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
MC1969A1 true MC1969A1 (fr) | 1989-09-29 |
Family
ID=10622364
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MC882000A MC1969A1 (fr) | 1987-08-15 | 1988-08-11 | Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation |
Country Status (28)
Country | Link |
---|---|
US (5) | US5091531A (ru) |
EP (1) | EP0305093B1 (ru) |
JP (1) | JPS6468375A (ru) |
KR (1) | KR890003764A (ru) |
CN (2) | CN1031532A (ru) |
AP (1) | AP89A (ru) |
AT (1) | ATE103919T1 (ru) |
AU (1) | AU613392B2 (ru) |
CA (1) | CA1336432C (ru) |
DD (1) | DD289529A5 (ru) |
DE (1) | DE3888897T2 (ru) |
DK (1) | DK168954B1 (ru) |
ES (1) | ES2063039T3 (ru) |
FI (1) | FI89600C (ru) |
GB (1) | GB8719368D0 (ru) |
HU (1) | HU204052B (ru) |
IL (1) | IL87435A (ru) |
MC (1) | MC1969A1 (ru) |
MX (1) | MX12655A (ru) |
MY (1) | MY103602A (ru) |
NO (1) | NO168305C (ru) |
NZ (1) | NZ225808A (ru) |
PH (1) | PH25741A (ru) |
PL (3) | PL159008B1 (ru) |
PT (1) | PT88260B (ru) |
RU (3) | RU1769759C (ru) |
YU (3) | YU47200B (ru) |
ZA (1) | ZA885996B (ru) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8719368D0 (en) * | 1987-08-15 | 1987-09-23 | Wellcome Found | Heterocyclic compounds |
PH27291A (en) * | 1989-01-31 | 1993-05-04 | Takeda Chemical Industries Ltd | Imidazolpyrimidazines their production and use |
EP0440119A1 (en) * | 1990-01-31 | 1991-08-07 | Takeda Chemical Industries, Ltd. | Imidazopyridazine compounds, their production and use |
ATE117690T1 (de) * | 1990-03-01 | 1995-02-15 | Takeda Chemical Industries Ltd | Imidazopyridazine, ihre herstellung und verwendung. |
KR20010087738A (ko) * | 1998-10-21 | 2001-09-21 | 다케다 야쿠힌 고교 가부시키가이샤 | 축합 피리다진 유도체, 이의 제조 방법 및 용도 |
SK18412002A3 (sk) | 2000-06-30 | 2003-06-03 | Wyeth | Použitie substituovaných triazolopyrimidínových derivátov a farmaceutický prostriedok s ich obsahom |
JP3767352B2 (ja) | 2000-09-18 | 2006-04-19 | トヨタ自動車株式会社 | 内燃機関の制御装置 |
US6960584B2 (en) * | 2001-04-10 | 2005-11-01 | Merck & Co., Inc. | Inhibitors of Akt activity |
CA2659971A1 (en) * | 2006-08-04 | 2008-02-07 | Takeda Pharmaceutical Company Limited | Fused heterocyclic derivative and use thereof |
CA2667487C (en) * | 2006-11-06 | 2017-04-04 | Supergen, Inc. | Imidazo[1,2-b]pyridazine and pyrazolo[1,5-a]pyrimidine derivatives and their use as protein kinase inhibitors |
US8431608B2 (en) | 2007-08-17 | 2013-04-30 | Icagen Inc. | Heterocycles as potassium channel modulators |
US8058274B2 (en) * | 2007-08-17 | 2011-11-15 | Icagen, Inc. | Heterocycles as potassium channel modulators |
WO2009106577A1 (en) * | 2008-02-28 | 2009-09-03 | Novartis Ag | Imidazo [1,2-b] pyridazine derivatives for the treatment of c-met tyrosine kinase mediated disease |
WO2009128520A1 (ja) * | 2008-04-18 | 2009-10-22 | 塩野義製薬株式会社 | P13k阻害活性を有する複素環化合物 |
UY32049A (es) * | 2008-08-14 | 2010-03-26 | Takeda Pharmaceutical | Inhibidores de cmet |
TW201437211A (zh) * | 2013-03-01 | 2014-10-01 | Bayer Pharma AG | 經取代咪唑并嗒□ |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB305093A (en) * | 1928-01-30 | 1929-07-25 | British Continental Motors Ltd | Improvements relating to induction passages of sleeve-valve internal combustion engines |
US3809691A (en) * | 1967-10-23 | 1974-05-07 | Eastman Kodak Co | Novel cyanine dyes with fused imidazolo nuclei |
US3615639A (en) * | 1967-10-23 | 1971-10-26 | Eastman Kodak Co | Direct positive silver halide emulsions containing dyes as electron acceptors and spectral sensitizers |
DE2043811A1 (en) * | 1970-09-03 | 1972-03-09 | E.I. du Pont de Nemours and Co., Wilmington, Del. (V.StA.) | Fungicidal and acaricidal alkyl 2-benzimi- - dazole carbomate derivs |
US3725407A (en) * | 1971-04-08 | 1973-04-03 | American Cyanamid Co | 6-substituted amino-3-nitroimidazo(1,2-b)pyridazines and methods of preparing the same |
FR2315507A1 (fr) * | 1975-06-26 | 1977-01-21 | Roussel Uclaf | Imidazo /1,2-b/ pyridazines substituees, procede de preparation et compositions pesticides les renfermant |
US4105767A (en) * | 1977-03-28 | 1978-08-08 | Merck & Co., Inc. | Imidazo [1,2-a] pyridines substituted with a thienyl, thiazolyl, or thiadiazolyl group |
US4166851A (en) * | 1977-05-16 | 1979-09-04 | Merck & Co., Inc. | Certain imidazo(1,2a)pyridine derivatives |
US4154835A (en) * | 1977-10-12 | 1979-05-15 | Merck & Co., Inc. | Anthelmintic imidazo [1,2-a] pyridines |
US4330543A (en) * | 1978-12-14 | 1982-05-18 | Merck & Co., Inc. | Imidazoazines and imidazodiazines |
US4221796A (en) * | 1979-09-19 | 1980-09-09 | E. R. Squibb & Sons, Inc. | Substituted imidazolo-pyridines and method |
DE3131365A1 (de) * | 1981-08-07 | 1983-02-24 | Henkel KGaA, 4000 Düsseldorf | Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit |
JPS58126887A (ja) * | 1981-09-26 | 1983-07-28 | Takeda Chem Ind Ltd | 新規7−デアザプリン誘導体 |
US4460773A (en) * | 1982-02-05 | 1984-07-17 | Lion Corporation | 1-Phenyl-1H-pyrazolo [3,4-b]pyrazine derivatives and process for preparing same |
US4464372A (en) * | 1982-08-16 | 1984-08-07 | Schering Corporation | Imidazo[1,2-b]pyridazines |
IL69417A (en) * | 1982-08-27 | 1987-12-20 | Roussel Uclaf | 2-acyl imidazo(1,2-a)pyrimidines,their preparation and pharmaceutical compositions containing them |
US4654347A (en) * | 1983-06-23 | 1987-03-31 | American Cyanamid Company | Aryl and heteroaryl[[7-(3-disubstituted amino)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]methanones |
DE3401911A1 (de) * | 1984-01-20 | 1985-08-01 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 4,5-dihydro-6-vinyl-3(2h)-pyridazinone und 6-vinyl-3(2h)-pyridazinone sowie verfahren zu ihrer herstellung |
DE3423092A1 (de) * | 1984-06-22 | 1986-01-02 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel |
US4569934A (en) * | 1984-10-09 | 1986-02-11 | American Cyanamid Company | Imidazo[1,2-b]pyridazines |
DE3446778A1 (de) * | 1984-12-21 | 1986-07-03 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
DE3446812A1 (de) * | 1984-12-21 | 1986-06-26 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue imidazoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
DE3527036A1 (de) * | 1985-07-27 | 1987-02-05 | Merck Patent Gmbh | 6-arylalkenylpyridazinone |
DE3542661A1 (de) * | 1985-12-03 | 1987-06-04 | Bayer Ag | Imidazopyridazinalkensaeureamide, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung |
WO1989001478A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | ARYLOXY- AND ARALKYLTHIO-IMIDAZO[1,2-b]PYRIDAZINES |
WO1989001333A1 (en) * | 1987-08-07 | 1989-02-23 | The Australian National University | IMIDAZO[1,2-b]PYRIDAZINES |
GB8719368D0 (en) * | 1987-08-15 | 1987-09-23 | Wellcome Found | Heterocyclic compounds |
-
1987
- 1987-08-15 GB GB878719368A patent/GB8719368D0/en active Pending
-
1988
- 1988-08-10 AP APAP/P/1988/000098A patent/AP89A/en active
- 1988-08-11 MC MC882000A patent/MC1969A1/xx unknown
- 1988-08-12 PL PL1988274216A patent/PL159008B1/pl unknown
- 1988-08-12 YU YU156988A patent/YU47200B/sh unknown
- 1988-08-12 PH PH37401A patent/PH25741A/en unknown
- 1988-08-12 RU SU884356488A patent/RU1769759C/ru active
- 1988-08-12 EP EP88307513A patent/EP0305093B1/en not_active Expired - Lifetime
- 1988-08-12 HU HU884333A patent/HU204052B/hu not_active IP Right Cessation
- 1988-08-12 AT AT88307513T patent/ATE103919T1/de not_active IP Right Cessation
- 1988-08-12 US US07/231,894 patent/US5091531A/en not_active Expired - Fee Related
- 1988-08-12 ES ES88307513T patent/ES2063039T3/es not_active Expired - Lifetime
- 1988-08-12 CN CN88106693A patent/CN1031532A/zh active Pending
- 1988-08-12 AU AU20979/88A patent/AU613392B2/en not_active Ceased
- 1988-08-12 DK DK451588A patent/DK168954B1/da not_active IP Right Cessation
- 1988-08-12 FI FI883758A patent/FI89600C/fi not_active IP Right Cessation
- 1988-08-12 MX MX1265588A patent/MX12655A/es unknown
- 1988-08-12 PL PL1988290245A patent/PL160044B1/pl unknown
- 1988-08-12 NZ NZ225808A patent/NZ225808A/en unknown
- 1988-08-12 CA CA000574614A patent/CA1336432C/en not_active Expired - Fee Related
- 1988-08-12 PL PL1988290246A patent/PL160045B1/pl unknown
- 1988-08-12 NO NO883613A patent/NO168305C/no unknown
- 1988-08-12 IL IL87435A patent/IL87435A/xx not_active IP Right Cessation
- 1988-08-12 KR KR1019880010374A patent/KR890003764A/ko not_active Application Discontinuation
- 1988-08-12 DE DE3888897T patent/DE3888897T2/de not_active Expired - Fee Related
- 1988-08-12 MY MYPI88000935A patent/MY103602A/en unknown
- 1988-08-12 PT PT88260A patent/PT88260B/pt not_active IP Right Cessation
- 1988-08-12 JP JP63200321A patent/JPS6468375A/ja active Pending
- 1988-08-12 DD DD88318868A patent/DD289529A5/de not_active IP Right Cessation
- 1988-08-12 ZA ZA885996A patent/ZA885996B/xx unknown
-
1989
- 1989-06-19 RU SU894614566A patent/RU2017741C1/ru active
- 1989-07-25 RU SU894614684A patent/RU1836372C/ru active
- 1989-10-18 YU YU202889A patent/YU47212B/sh unknown
- 1989-10-18 YU YU202789A patent/YU47130B/sh unknown
-
1993
- 1993-03-31 CN CN93103896A patent/CN1085901A/zh active Pending
- 1993-09-17 US US08/122,699 patent/US5371219A/en not_active Expired - Fee Related
- 1993-09-17 US US08/123,529 patent/US5380759A/en not_active Expired - Fee Related
-
1994
- 1994-07-08 US US08/272,009 patent/US5447956A/en not_active Expired - Fee Related
-
1995
- 1995-06-02 US US08/458,225 patent/US5538970A/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MC1969A1 (fr) | Procedes pour preparer des composes antitumoraux,formulation pharmaceutique contenant ces composes,leurs utilisations en medecine et pharmacie,et composes intermediaires pour leur preparation | |
IT1178193B (it) | Perfezionamento nelle capsule divisibili per la somministrazione dosata di prodotti farmaceutici | |
PT77503A (en) | Process for preparing pharmaceutical compositions for oral and/or enteral administration | |
IT8721668A0 (it) | Insufflatore per la somministrazione di farmaci sottoforma di polvere predosata in opercoli. | |
AU627845B2 (en) | Improvements in or relating to devices for administration of drugs or the like | |
ES8104720A1 (es) | Un procedimiento para la preparacion de composiciones lipo- somicas de substancias activas grasosolubles | |
IL86877A (en) | Carbazole derivatives,their preparation and pharmaceutical compositions containing them | |
MA18829A1 (fr) | Derives de la pyrimidine,procedes pour leur preparation,compositions pharmaceutiques contenant ces composes et leur utilisation therapeutique | |
LTIP915A (en) | Catehol derivatives,methods for their preparation and pharmaceutical compositions containing them | |
FR2633624B1 (fr) | Carboxamide, procedes pour le preparer et composition pharmaceutique le contenant | |
IL85247A (en) | Polyamine derivatives,process for their preparation and pharmaceutical compositions containing them | |
ATE84032T1 (de) | Benzimidazolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate. | |
FR2628324B1 (fr) | Compositions pharmaceutiques antivirales et immunostimulantes et procede pour les preparer | |
DE2966142D1 (en) | Quinolein-3-carboxylic acid derivatives, process for their preparation, their use in medicines and pharmaceutical compositions containing them | |
FR2628425B1 (fr) | Derives d'isoindolinone, leurs procedes de preparation et les medicaments les contenant | |
DE3787178D1 (de) | Behälter zur Verabreichung eines Heilmittels in einem Zufuhrsystem. | |
FR2599034B1 (fr) | Derives de 1-(hydroxystyryl)-5h-2,3,-benzodiazepine, procede pour les preparer et compositions pharmaceutiques les contenant | |
BE874252A (fr) | Nouvelles 2-phenylimino-imidazolidines substituees, leurs sels d'addition avec des acides, medicaments les renfermant et procedes pour leur preparation | |
BE878028A (fr) | Nouvelles imidazoquinoxalines et leurs sels, leur procede de preparation, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant | |
BE874253A (fr) | Nouvelles 2-phenylimino-imidazolidines substituees, leurs sels d'addition avec des acides, medicaments les renfermant et procedes pour leur preparation | |
FR2668148B1 (fr) | Nouveau derive de 5h-benzodiazepine, compositions pharmaceutiques le contenant et procede pour les preparer. | |
IL61240A0 (en) | Quinazoline derivatives, their preparation and pharmaceutical compositions containing them | |
IL88617A0 (en) | Quinoline derivatives,the preparation thereof and pharmaceutical compositions containing them | |
FR2621918B1 (fr) | 2',3'-didesoxy-4-thio-uridines, procede de preparation de ces substances et medicaments qui en contiennent | |
FR2675144B1 (fr) | Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
YP | Annual fee paid |