MA44820B1 - Amides hétérocycliques a utiliser en tant qu'inhibiteurs de kinase - Google Patents

Amides hétérocycliques a utiliser en tant qu'inhibiteurs de kinase

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Publication number
MA44820B1
MA44820B1 MA44820A MA44820A MA44820B1 MA 44820 B1 MA44820 B1 MA 44820B1 MA 44820 A MA44820 A MA 44820A MA 44820 A MA44820 A MA 44820A MA 44820 B1 MA44820 B1 MA 44820B1
Authority
MA
Morocco
Prior art keywords
kinase inhibitors
heterocyclic amides
amides
heterocyclic
compounds
Prior art date
Application number
MA44820A
Other languages
English (en)
Other versions
MA44820A1 (fr
Inventor
Deepak Bandyopadhyay
Jianxing Kang
Marquis, Jr
Joshi M Ramanjulu
Singhaus, Jr
Patrick M Eidam
Peter J Gough
Philip Anthony Harris
Jae U Jeong
Bryan Wayne King
Shah Ami Lakdawala
Lara Kathryn Leister
Attiq Rahman
Clark A Sehon
Daohua Zhang
Original Assignee
Glaxosmithkline Ip Dev Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Ip Dev Ltd filed Critical Glaxosmithkline Ip Dev Ltd
Publication of MA44820A1 publication Critical patent/MA44820A1/fr
Publication of MA44820B1 publication Critical patent/MA44820B1/fr

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
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    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems

Abstract

L'invention concerne des composés de formule (i) dans laquelle x, y, z1, z2, z3, z4, r5, ra, m, a. L, et b ont la signification indiquée dans la description, ainsi que des procédés de fabrication et d'utilisation de ceux-ci.
MA44820A 2013-02-15 2014-02-14 Amides hétérocycliques a utiliser en tant qu'inhibiteurs de kinase MA44820B1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361765664P 2013-02-15 2013-02-15
US201361790044P 2013-03-15 2013-03-15
PCT/IB2014/059004 WO2014125444A1 (fr) 2013-02-15 2014-02-14 Amides hétérocycliques à utiliser en tant qu'inhibiteurs de kinase

Publications (2)

Publication Number Publication Date
MA44820A1 MA44820A1 (fr) 2019-09-30
MA44820B1 true MA44820B1 (fr) 2020-06-30

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