LV11030B - Novel morpholinol compounds, their preparation and use - Google Patents

Novel morpholinol compounds, their preparation and use Download PDF

Info

Publication number
LV11030B
LV11030B LVP-95-27A LV950027A LV11030B LV 11030 B LV11030 B LV 11030B LV 950027 A LV950027 A LV 950027A LV 11030 B LV11030 B LV 11030B
Authority
LV
Latvia
Prior art keywords
formula
compound
salt
group
morpholinol
Prior art date
Application number
LVP-95-27A
Other languages
English (en)
Latvian (lv)
Other versions
LV11030A (lv
Inventor
James Leroy Kelley
David Lee Musso
Grady Evan Boswell
Barrett Randolph Cooper
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of LV11030A publication Critical patent/LV11030A/xx
Publication of LV11030B publication Critical patent/LV11030B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/321,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
LVP-95-27A 1989-10-31 1995-02-09 Novel morpholinol compounds, their preparation and use LV11030B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898924528A GB8924528D0 (en) 1989-10-31 1989-10-31 Heterocyclic pharmaceutical compounds,preparation and use

Publications (2)

Publication Number Publication Date
LV11030A LV11030A (lv) 1996-02-20
LV11030B true LV11030B (en) 1996-08-20

Family

ID=10665482

Family Applications (1)

Application Number Title Priority Date Filing Date
LVP-95-27A LV11030B (en) 1989-10-31 1995-02-09 Novel morpholinol compounds, their preparation and use

Country Status (19)

Country Link
US (1) US5104870A (fr)
EP (1) EP0426416B1 (fr)
JP (1) JP2873076B2 (fr)
AT (1) ATE101604T1 (fr)
AU (1) AU645763B2 (fr)
CA (1) CA2028893C (fr)
DE (1) DE69006682T2 (fr)
DK (1) DK0426416T3 (fr)
ES (1) ES2062406T3 (fr)
FI (1) FI94753C (fr)
GB (1) GB8924528D0 (fr)
HU (2) HU207304B (fr)
IE (1) IE66115B1 (fr)
LV (1) LV11030B (fr)
MX (1) MX9203219A (fr)
NZ (1) NZ235882A (fr)
PT (1) PT95735B (fr)
SG (1) SG28347G (fr)
ZA (1) ZA908696B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
AU1403899A (en) * 1997-11-14 1999-06-07 Glaxo Group Limited Method of treating addiction to nicotine products
MA26693A1 (fr) * 1998-09-28 2004-12-20 Glaxo Group Ltd Compositions pour administration par voie buccale
AU7750100A (en) * 1999-10-13 2001-04-23 Glaxo Group Limited Method for the treatment of obesity
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法
US7763612B2 (en) * 2006-01-03 2010-07-27 Algebra, Inc. Therapeutic amine-arylsulfonamide conjugate compounds
AU2010236404B2 (en) 2009-04-15 2016-11-03 Research Triangle Institute Monoamine reuptake inhibitors
AU2011255276B2 (en) 2010-05-21 2016-09-22 Research Triangle Institute Phenylmorpholines and analogues thereof
AU2011255456B2 (en) * 2010-05-21 2017-01-19 Dignity Health Doing Business As St. Joseph's Hospital And Medical Center And Barrow Neurological Institute 1 - phenylmorpholine derivatives as hydroxybupropion analogues for treating drug dependence
CN105949142B (zh) * 2016-05-21 2018-03-27 南华大学 具有抗抑郁活性的单一手性化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117967A (en) * 1962-04-02 1964-01-14 Smith Kline French Lab 2-biphenylyl-2-hydroxy-morpholinium halides
FR2553413B1 (fr) * 1983-10-17 1986-03-21 Lafon Labor Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique
GB8417170D0 (en) * 1984-07-05 1984-08-08 Wellcome Found Heterocyclic pharmaceutical compounds

Also Published As

Publication number Publication date
PT95735B (pt) 1998-01-30
EP0426416A1 (fr) 1991-05-08
DE69006682T2 (de) 1994-08-04
DE69006682D1 (de) 1994-03-24
HU906935D0 (en) 1991-05-28
ATE101604T1 (de) 1994-03-15
ES2062406T3 (es) 1994-12-16
MX9203219A (es) 1992-07-01
LV11030A (lv) 1996-02-20
FI905356A0 (fi) 1990-10-30
PT95735A (pt) 1991-09-13
JPH03206084A (ja) 1991-09-09
FI94753C (fi) 1995-10-25
CA2028893A1 (fr) 1991-05-01
CA2028893C (fr) 2000-10-10
AU6563990A (en) 1991-05-09
AU645763B2 (en) 1994-01-27
SG28347G (en) 1995-09-18
IE66115B1 (en) 1995-12-13
US5104870A (en) 1992-04-14
HU211304A9 (en) 1995-11-28
DK0426416T3 (da) 1994-03-14
JP2873076B2 (ja) 1999-03-24
IE903888A1 (en) 1991-05-08
HU207304B (en) 1993-03-29
NZ235882A (en) 1993-05-26
FI94753B (fi) 1995-07-14
ZA908696B (en) 1992-07-29
GB8924528D0 (en) 1989-12-20
HUT57748A (en) 1991-12-30
EP0426416B1 (fr) 1994-02-16

Similar Documents

Publication Publication Date Title
KR100523366B1 (ko) 티에닐아졸일알콕시에탄아민, 이의 제조방법 및 이의 용도
JPH0819065B2 (ja) ベンゾ融合シクロアルカンおよびオキサ‐およびチア‐シクロアルカントランス‐1,2‐ジアミン誘導体
US5648347A (en) Arylmorpholine, preparation and use
LV11030B (en) Novel morpholinol compounds, their preparation and use
KR0166661B1 (ko) 5-ht3 길항제로서 디메틸벤조푸란 및 디메틸벤조피란의 용도
US4010202A (en) 5,6-Dihydroxy aminotetralol compounds
JPH05262766A (ja) ピペリジルメチル−置換クロマン誘導体
US4490392A (en) Benzylalcohol derivative and process for preparing
EP0034647B1 (fr) Dérivés de 4-aryloxy-3-phényl-pipéridine, produits intermédiaires, procédé pour leur préparation et leur utilisation comme médicaments
JPS648621B2 (fr)
US4598088A (en) 2-pyrrolyl-cycloalkyl-amide analgesics
US4104402A (en) 5,6-Dihydroxy aminotetralol compounds
US4831049A (en) Pyrrolizidine compounds, and their use as antiarrhythmic agents
EP0116372B1 (fr) Dérivés de la 2H-(1)benzoxépino(5,4-b)-1,4-oxazine
RU2204560C2 (ru) Производные тетрагидроимидазо [2,1-а]изохинолина и фармацевтический препарат на их основе
FR2462426A1 (fr) Nouveau derive de la 2-(1-naphtyl)piperidine, sa preparation et son application comme medicament
BE893095Q (fr) Phenylpiperidines leur preparation et leur utilisation
WO2010112597A1 (fr) Dérivés d'aminocyclobutane ou d'aminocyclobutène, leur procédé de préparation et leur utilisation comme produits médicaux
JPH064566B2 (ja) 含窒素テルペンアルコ−ル類及びこれを有効成分とする抗アレルギ−剤
CH410951A (fr) Procédé de préparation de dérivés de la pyrrolidine
CH435281A (fr) Procédé de préparation de dérivés de la pyrrolidine
CH435286A (fr) Procédé de préparation de dérivés de la pyrrolidine