ATE101604T1 - Neue morpholinol-verbindungen, deren herstellung und anwendung. - Google Patents

Neue morpholinol-verbindungen, deren herstellung und anwendung.

Info

Publication number
ATE101604T1
ATE101604T1 AT90311851T AT90311851T ATE101604T1 AT E101604 T1 ATE101604 T1 AT E101604T1 AT 90311851 T AT90311851 T AT 90311851T AT 90311851 T AT90311851 T AT 90311851T AT E101604 T1 ATE101604 T1 AT E101604T1
Authority
AT
Austria
Prior art keywords
compounds
morpholinol
preparation
new
application
Prior art date
Application number
AT90311851T
Other languages
English (en)
Inventor
James Leroy Kelley
David Lee Musso
Grady Evan Boswell
Barrett Randolph Cooper
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Application granted granted Critical
Publication of ATE101604T1 publication Critical patent/ATE101604T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90311851T 1989-10-31 1990-10-30 Neue morpholinol-verbindungen, deren herstellung und anwendung. ATE101604T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898924528A GB8924528D0 (en) 1989-10-31 1989-10-31 Heterocyclic pharmaceutical compounds,preparation and use

Publications (1)

Publication Number Publication Date
ATE101604T1 true ATE101604T1 (de) 1994-03-15

Family

ID=10665482

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90311851T ATE101604T1 (de) 1989-10-31 1990-10-30 Neue morpholinol-verbindungen, deren herstellung und anwendung.

Country Status (19)

Country Link
US (1) US5104870A (de)
EP (1) EP0426416B1 (de)
JP (1) JP2873076B2 (de)
AT (1) ATE101604T1 (de)
AU (1) AU645763B2 (de)
CA (1) CA2028893C (de)
DE (1) DE69006682T2 (de)
DK (1) DK0426416T3 (de)
ES (1) ES2062406T3 (de)
FI (1) FI94753C (de)
GB (1) GB8924528D0 (de)
HU (2) HU207304B (de)
IE (1) IE66115B1 (de)
LV (1) LV11030B (de)
MX (1) MX9203219A (de)
NZ (1) NZ235882A (de)
PT (1) PT95735B (de)
SG (1) SG28347G (de)
ZA (1) ZA908696B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9108629D0 (en) * 1991-04-23 1991-06-12 Wellcome Found Heterocyclic pharmaceutical compounds,preparation and use
AU1403899A (en) * 1997-11-14 1999-06-07 Glaxo Group Limited Method of treating addiction to nicotine products
MA26693A1 (fr) * 1998-09-28 2004-12-20 Glaxo Group Ltd Compositions pour administration par voie buccale
AU7750100A (en) * 1999-10-13 2001-04-23 Glaxo Group Limited Method for the treatment of obesity
JP4625637B2 (ja) 2002-02-22 2011-02-02 シャイア エルエルシー 活性物質送達系及び活性物質を保護し投与する方法
CA2635261A1 (en) * 2006-01-03 2007-07-12 Algebra, Inc. Therapeutic amine-arylsulfonamide conjugate compounds
EP2419400A1 (de) 2009-04-15 2012-02-22 Research Triangle Institute Monoaminwiederaufnahmehemmer
JP2013526583A (ja) 2010-05-21 2013-06-24 リサーチ・トライアングル・インスティチュート フェニルモルホリンおよびその類似体
JP5952267B2 (ja) * 2010-05-21 2016-07-13 リサーチ・トライアングル・インスティチュート 薬物依存を処置するためのヒドロキシブプロピオン類似体（政府支援研究または開発）
CN105949142B (zh) * 2016-05-21 2018-03-27 南华大学 具有抗抑郁活性的单一手性化合物及其制备方法和应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3117967A (en) * 1962-04-02 1964-01-14 Smith Kline French Lab 2-biphenylyl-2-hydroxy-morpholinium halides
FR2553413B1 (fr) * 1983-10-17 1986-03-21 Lafon Labor Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique
GB8417170D0 (en) * 1984-07-05 1984-08-08 Wellcome Found Heterocyclic pharmaceutical compounds

Also Published As

Publication number Publication date
SG28347G (en) 1995-09-18
PT95735A (pt) 1991-09-13
PT95735B (pt) 1998-01-30
MX9203219A (es) 1992-07-01
EP0426416A1 (de) 1991-05-08
AU6563990A (en) 1991-05-09
HU207304B (en) 1993-03-29
GB8924528D0 (en) 1989-12-20
LV11030B (en) 1996-08-20
JP2873076B2 (ja) 1999-03-24
DK0426416T3 (da) 1994-03-14
FI94753B (fi) 1995-07-14
AU645763B2 (en) 1994-01-27
IE903888A1 (en) 1991-05-08
FI94753C (fi) 1995-10-25
JPH03206084A (ja) 1991-09-09
IE66115B1 (en) 1995-12-13
CA2028893A1 (en) 1991-05-01
HUT57748A (en) 1991-12-30
ZA908696B (en) 1992-07-29
HU906935D0 (en) 1991-05-28
US5104870A (en) 1992-04-14
DE69006682D1 (de) 1994-03-24
ES2062406T3 (es) 1994-12-16
HU211304A9 (en) 1995-11-28
EP0426416B1 (de) 1994-02-16
NZ235882A (en) 1993-05-26
LV11030A (lv) 1996-02-20
DE69006682T2 (de) 1994-08-04
CA2028893C (en) 2000-10-10
FI905356A0 (fi) 1990-10-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee