CA2028893A1 - Morpholinoles, leur prepation et utilisation - Google Patents
Morpholinoles, leur prepation et utilisationInfo
- Publication number
- CA2028893A1 CA2028893A1 CA2028893A CA2028893A CA2028893A1 CA 2028893 A1 CA2028893 A1 CA 2028893A1 CA 2028893 A CA2028893 A CA 2028893A CA 2028893 A CA2028893 A CA 2028893A CA 2028893 A1 CA2028893 A1 CA 2028893A1
- Authority
- CA
- Canada
- Prior art keywords
- morpholinols
- carbon atoms
- prepation
- cycloalkyl
- racemates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
- C07D265/32—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings with oxygen atoms directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898924528A GB8924528D0 (en) | 1989-10-31 | 1989-10-31 | Heterocyclic pharmaceutical compounds,preparation and use |
| GB8924528.6 | 1989-10-31 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2028893A1 true CA2028893A1 (fr) | 1991-05-01 |
| CA2028893C CA2028893C (fr) | 2000-10-10 |
Family
ID=10665482
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002028893A Expired - Fee Related CA2028893C (fr) | 1989-10-31 | 1990-10-30 | Morpholinoles, leur prepation et utilisation |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5104870A (fr) |
| EP (1) | EP0426416B1 (fr) |
| JP (1) | JP2873076B2 (fr) |
| AT (1) | ATE101604T1 (fr) |
| AU (1) | AU645763B2 (fr) |
| CA (1) | CA2028893C (fr) |
| DE (1) | DE69006682T2 (fr) |
| DK (1) | DK0426416T3 (fr) |
| ES (1) | ES2062406T3 (fr) |
| FI (1) | FI94753C (fr) |
| GB (1) | GB8924528D0 (fr) |
| HU (2) | HU207304B (fr) |
| IE (1) | IE66115B1 (fr) |
| LV (1) | LV11030B (fr) |
| MX (1) | MX9203219A (fr) |
| NZ (1) | NZ235882A (fr) |
| PT (1) | PT95735B (fr) |
| SG (1) | SG28347G (fr) |
| ZA (1) | ZA908696B (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9108629D0 (en) * | 1991-04-23 | 1991-06-12 | Wellcome Found | Heterocyclic pharmaceutical compounds,preparation and use |
| WO1999025355A1 (fr) * | 1997-11-14 | 1999-05-27 | Glaxo Group Ltd. | Procede de traitement de l'accoutumance a des produits contenant de la nicotine |
| MA26693A1 (fr) * | 1998-09-28 | 2004-12-20 | Glaxo Group Ltd | Compositions pour administration par voie buccale |
| AU7750100A (en) * | 1999-10-13 | 2001-04-23 | Glaxo Group Limited | Method for the treatment of obesity |
| IL163666A0 (en) | 2002-02-22 | 2005-12-18 | New River Pharmaceuticals Inc | Active agent delivery systems and methods for protecting and administering active agents |
| EP1968603A4 (fr) * | 2006-01-03 | 2013-01-16 | Algebra Inc | Composes therapeutiques amine-arylsulfonamide conjugues |
| AU2010236404B2 (en) | 2009-04-15 | 2016-11-03 | Research Triangle Institute | Monoamine reuptake inhibitors |
| WO2011146821A2 (fr) | 2010-05-21 | 2011-11-24 | Research Triangle Institute | Analogues d'hydroxybupropion pour le traitement de la pharmacodépendance |
| AU2011255276B2 (en) | 2010-05-21 | 2016-09-22 | Research Triangle Institute | Phenylmorpholines and analogues thereof |
| CN105949142B (zh) * | 2016-05-21 | 2018-03-27 | 南华大学 | 具有抗抑郁活性的单一手性化合物及其制备方法和应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3117967A (en) * | 1962-04-02 | 1964-01-14 | Smith Kline French Lab | 2-biphenylyl-2-hydroxy-morpholinium halides |
| FR2553413B1 (fr) * | 1983-10-17 | 1986-03-21 | Lafon Labor | Derives de 4-alkyl-2-hydroxy-3-methyl-2-phenyl-morpholine, procede de preparation et utilisation en therapeutique |
| GB8417170D0 (en) * | 1984-07-05 | 1984-08-08 | Wellcome Found | Heterocyclic pharmaceutical compounds |
-
1989
- 1989-10-31 GB GB898924528A patent/GB8924528D0/en active Pending
-
1990
- 1990-10-30 AU AU65639/90A patent/AU645763B2/en not_active Ceased
- 1990-10-30 SG SG1995904223A patent/SG28347G/en unknown
- 1990-10-30 EP EP90311851A patent/EP0426416B1/fr not_active Expired - Lifetime
- 1990-10-30 ZA ZA908696A patent/ZA908696B/xx unknown
- 1990-10-30 ES ES90311851T patent/ES2062406T3/es not_active Expired - Lifetime
- 1990-10-30 AT AT90311851T patent/ATE101604T1/de not_active IP Right Cessation
- 1990-10-30 HU HU906935A patent/HU207304B/hu not_active IP Right Cessation
- 1990-10-30 NZ NZ235882A patent/NZ235882A/xx unknown
- 1990-10-30 CA CA002028893A patent/CA2028893C/fr not_active Expired - Fee Related
- 1990-10-30 JP JP2293476A patent/JP2873076B2/ja not_active Expired - Fee Related
- 1990-10-30 DK DK90311851.1T patent/DK0426416T3/da active
- 1990-10-30 IE IE388890A patent/IE66115B1/en not_active IP Right Cessation
- 1990-10-30 DE DE69006682T patent/DE69006682T2/de not_active Expired - Fee Related
- 1990-10-30 FI FI905356A patent/FI94753C/fi not_active IP Right Cessation
- 1990-10-30 PT PT95735A patent/PT95735B/pt not_active IP Right Cessation
-
1991
- 1991-04-02 US US07/680,637 patent/US5104870A/en not_active Expired - Lifetime
-
1992
- 1992-06-24 MX MX9203219A patent/MX9203219A/es unknown
-
1995
- 1995-02-09 LV LVP-95-27A patent/LV11030B/en unknown
- 1995-05-09 HU HU95P/P00125P patent/HU211304A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU207304B (en) | 1993-03-29 |
| SG28347G (en) | 1995-09-18 |
| FI94753B (fi) | 1995-07-14 |
| DE69006682T2 (de) | 1994-08-04 |
| NZ235882A (en) | 1993-05-26 |
| JPH03206084A (ja) | 1991-09-09 |
| MX9203219A (es) | 1992-07-01 |
| DK0426416T3 (da) | 1994-03-14 |
| HU906935D0 (en) | 1991-05-28 |
| PT95735A (pt) | 1991-09-13 |
| ZA908696B (en) | 1992-07-29 |
| ATE101604T1 (de) | 1994-03-15 |
| IE903888A1 (en) | 1991-05-08 |
| GB8924528D0 (en) | 1989-12-20 |
| FI905356A0 (fi) | 1990-10-30 |
| ES2062406T3 (es) | 1994-12-16 |
| EP0426416B1 (fr) | 1994-02-16 |
| AU6563990A (en) | 1991-05-09 |
| PT95735B (pt) | 1998-01-30 |
| CA2028893C (fr) | 2000-10-10 |
| US5104870A (en) | 1992-04-14 |
| HUT57748A (en) | 1991-12-30 |
| LV11030B (en) | 1996-08-20 |
| FI94753C (fi) | 1995-10-25 |
| AU645763B2 (en) | 1994-01-27 |
| LV11030A (lv) | 1996-02-20 |
| JP2873076B2 (ja) | 1999-03-24 |
| DE69006682D1 (de) | 1994-03-24 |
| EP0426416A1 (fr) | 1991-05-08 |
| HU211304A9 (en) | 1995-11-28 |
| IE66115B1 (en) | 1995-12-13 |
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| CA2028893A1 (fr) | Morpholinoles, leur prepation et utilisation | |
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| KR880007070A (ko) | 백내장 치료용 약학 조성물 | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |