LU93169I2 - Lésinurad , ou un sel pharmaceutiquement acceptable de celui-ci - Google Patents

Lésinurad , ou un sel pharmaceutiquement acceptable de celui-ci Download PDF

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Publication number
LU93169I2
LU93169I2 LU93169C LU93169C LU93169I2 LU 93169 I2 LU93169 I2 LU 93169I2 LU 93169 C LU93169 C LU 93169C LU 93169 C LU93169 C LU 93169C LU 93169 I2 LU93169 I2 LU 93169I2
Authority
LU
Luxembourg
Prior art keywords
lésinurad
pharmaceutically acceptable
acceptable salt
hiv
mercaptoacetanilides
Prior art date
Application number
LU93169C
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English (en)
French (fr)
Original Assignee
Ardea Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36000576&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU93169(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ardea Biosciences Inc filed Critical Ardea Biosciences Inc
Publication of LU93169I2 publication Critical patent/LU93169I2/fr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Road Signs Or Road Markings (AREA)
  • Pens And Brushes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
LU93169C 2004-08-25 2016-08-10 Lésinurad , ou un sel pharmaceutiquement acceptable de celui-ci LU93169I2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US60421904P 2004-08-25 2004-08-25
US60422004P 2004-08-25 2004-08-25
US68635105P 2005-05-31 2005-05-31
EP05790722A EP1789039B1 (en) 2004-08-25 2005-08-25 S-triazolyl alpha -mercaptoacetanildes as inhibitors of hiv reverse transcriptase

Publications (1)

Publication Number Publication Date
LU93169I2 true LU93169I2 (fr) 2016-10-10

Family

ID=36000576

Family Applications (1)

Application Number Title Priority Date Filing Date
LU93169C LU93169I2 (fr) 2004-08-25 2016-08-10 Lésinurad , ou un sel pharmaceutiquement acceptable de celui-ci

Country Status (31)

Country Link
US (8) US7947721B2 (OSRAM)
EP (5) EP2433633A1 (OSRAM)
JP (2) JP4952943B2 (OSRAM)
KR (1) KR101241716B1 (OSRAM)
CN (2) CN101083987B (OSRAM)
AT (2) ATE528001T1 (OSRAM)
AU (2) AU2005280130C9 (OSRAM)
BR (2) BRPI0520870B8 (OSRAM)
CA (1) CA2578068C (OSRAM)
CY (2) CY1112221T1 (OSRAM)
DK (1) DK2135608T3 (OSRAM)
EA (2) EA015846B1 (OSRAM)
EC (1) ECSP077322A (OSRAM)
ES (2) ES2380604T3 (OSRAM)
FR (1) FR16C0031I2 (OSRAM)
HR (1) HRP20130075T1 (OSRAM)
HU (1) HUS1600034I1 (OSRAM)
IL (3) IL181523A (OSRAM)
IN (1) IN2014CN03762A (OSRAM)
LT (1) LTC2135608I2 (OSRAM)
LU (1) LU93169I2 (OSRAM)
ME (1) ME01512B (OSRAM)
MX (1) MX2007002236A (OSRAM)
NL (1) NL300825I2 (OSRAM)
NZ (2) NZ581376A (OSRAM)
PL (1) PL2135608T3 (OSRAM)
PT (1) PT2135608E (OSRAM)
RS (1) RS52632B (OSRAM)
SG (2) SG155246A1 (OSRAM)
SI (1) SI2135608T1 (OSRAM)
WO (1) WO2006026356A2 (OSRAM)

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US8173690B2 (en) * 2008-09-04 2012-05-08 Ardea Biosciences, Inc. Compounds, compositions and methods of using same for modulating uric acid levels
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CN105153056A (zh) * 2015-07-01 2015-12-16 安徽万邦医药科技有限公司 一种[5-溴-4-(4-环丙基萘-1-基)-4h-[1,2,4]三唑-3-基硫烷基]-乙酸甲酯的新制备方法
CN105017168A (zh) * 2015-07-01 2015-11-04 安徽万邦医药科技有限公司 一种[5-溴-4-(4-环丙基萘-1-基)-4h-[1,2,4]三唑-3-基硫烷基]-乙酸甲酯的新制备方法
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CN109476611B (zh) * 2016-06-17 2022-08-23 南京明德新药研发有限公司 一种卤代化合物及其轴手性异构体
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Publication number Publication date
JP2008510828A (ja) 2008-04-10
US20180002296A1 (en) 2018-01-04
AU2005280130A1 (en) 2006-03-09
IL219131A0 (en) 2012-06-28
US7947721B2 (en) 2011-05-24
ME01512B (me) 2014-04-20
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JP4952943B2 (ja) 2012-06-13
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EP2135608B8 (en) 2012-03-21
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EA200901186A1 (ru) 2010-04-30
FR16C0031I1 (OSRAM) 2016-09-23
AU2005280130B2 (en) 2009-09-10
LTC2135608I2 (lt) 2017-07-25
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IN2014CN03762A (OSRAM) 2015-09-25
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PL2135608T3 (pl) 2012-07-31
US20150094284A1 (en) 2015-04-02
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EA200700488A1 (ru) 2007-08-31
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ES2374773T3 (es) 2012-02-21
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KR20070054694A (ko) 2007-05-29
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US8481581B2 (en) 2013-07-09
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AU2009217458B2 (en) 2009-11-19
US20120283301A1 (en) 2012-11-08
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BRPI0514630B1 (pt) 2020-09-15
US20100069645A1 (en) 2010-03-18
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EP2402011B1 (en) 2012-11-14
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RS52632B (sr) 2013-06-28
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