LU90457I2 - Refacto - Google Patents

Refacto

Info

Publication number
LU90457I2
LU90457I2 LU90457C LU90457C LU90457I2 LU 90457 I2 LU90457 I2 LU 90457I2 LU 90457 C LU90457 C LU 90457C LU 90457 C LU90457 C LU 90457C LU 90457 I2 LU90457 I2 LU 90457I2
Authority
LU
Luxembourg
Prior art keywords
factor viii
human factor
dna segment
segment coding
coding
Prior art date
Application number
LU90457C
Other languages
English (en)
Original Assignee
Pharmacia & Upjohn Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20377785&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LU90457(I2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia & Upjohn Ab filed Critical Pharmacia & Upjohn Ab
Publication of LU90457I2 publication Critical patent/LU90457I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Confectionery (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Saccharide Compounds (AREA)
LU90457C 1989-12-15 1999-10-12 Refacto LU90457I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8904239A SE465222C5 (sv) 1989-12-15 1989-12-15 Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
PCT/SE1990/000809 WO1991009122A1 (fr) 1989-12-15 1990-12-06 Derive du facteur humain viii de recombinaison

Publications (1)

Publication Number Publication Date
LU90457I2 true LU90457I2 (fr) 2001-04-13

Family

ID=20377785

Family Applications (1)

Application Number Title Priority Date Filing Date
LU90457C LU90457I2 (fr) 1989-12-15 1999-10-12 Refacto

Country Status (21)

Country Link
EP (3) EP0786474B1 (fr)
JP (1) JP2644084B2 (fr)
AT (2) ATE232213T1 (fr)
AU (1) AU645539B2 (fr)
BR (1) BR9007921A (fr)
CA (1) CA2071875C (fr)
DE (3) DE19975066I2 (fr)
DK (2) DK0786474T3 (fr)
ES (2) ES2189897T3 (fr)
FI (1) FI104260B1 (fr)
HK (2) HK1019449A1 (fr)
HU (1) HU211504A9 (fr)
IE (1) IE904510A1 (fr)
LU (1) LU90457I2 (fr)
NL (1) NL990035I2 (fr)
NO (1) NO309041B1 (fr)
NZ (1) NZ236276A (fr)
PT (1) PT96208B (fr)
SE (1) SE465222C5 (fr)
SG (1) SG66753A1 (fr)
WO (1) WO1991009122A1 (fr)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
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US6346513B1 (en) 1987-06-12 2002-02-12 Baxter Trading Gmbh Proteins with factor VIII activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
US5171844A (en) 1987-06-12 1992-12-15 Gist-Brocades N.W. Proteins with factor viii activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
SE468050C (sv) * 1991-03-15 1998-02-11 Pharmacia & Upjohn Ab Rekombinant derivat av human faktor VIII
US5744446A (en) * 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
US5888974A (en) * 1992-04-07 1999-03-30 Emory University Hybrid human/animal factor VIII
US5364771A (en) * 1992-04-07 1994-11-15 Emory University Hybrid human/porcine factor VIII
US5663060A (en) * 1992-04-07 1997-09-02 Emory University Hybrid human/animal factor VIII
DK53792D0 (da) * 1992-04-24 1992-04-24 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
CA2124690C (fr) * 1992-10-02 2007-09-11 Thomas Osterberg Composition contenant une preparation du facteur de coagulation viii, methode de preparation et utilisation d'un surfactant comme stabilisateur
SE9300509D0 (sv) * 1993-02-16 1993-02-16 Kabi Pharmacia Ab Peg treatment
SE9301581D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Protein formulation
SE504074C2 (sv) * 1993-07-05 1996-11-04 Pharmacia Ab Proteinberedning för subkutan, intramuskulär eller intradermal administrering
SE9303601D0 (sv) * 1993-11-01 1993-11-01 Kabi Pharmacia Ab Improved cell cultivation method and medium
US6288030B1 (en) 1993-12-22 2001-09-11 Amgen Inc. Stem cell factor formulations and methods
IL113010A (en) * 1994-03-31 1999-10-28 Pharmacia & Upjohn Ab Pharmaceutical formulation comprising factor viii with an activity of at least 500iu/ml and an enhancer for improved subcutaneous intramuscular or intradermal administration
SE503424C2 (sv) * 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
SE9403915D0 (sv) * 1994-11-14 1994-11-14 Annelie Almstedt Process A
US6818439B1 (en) 1994-12-30 2004-11-16 Chiron Corporation Methods for administration of recombinant gene delivery vehicles for treatment of hemophilia and other disorders
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DK0506757T4 (da) 2006-02-20
NO922325L (no) 1992-08-11
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DE69034040T2 (de) 2003-11-20
PT96208A (pt) 1991-09-30
NO922325D0 (no) 1992-06-12
ATE170219T1 (de) 1998-09-15
DE69034040D1 (de) 2003-03-13
HU211504A9 (en) 1995-11-28
FI104260B (fi) 1999-12-15
CA2071875A1 (fr) 1991-06-16
CA2071875C (fr) 2006-08-08
ES2119769T5 (es) 2006-04-16
JPH05502161A (ja) 1993-04-22
EP1293513A2 (fr) 2003-03-19
PT96208B (pt) 1998-05-29
ATE232213T1 (de) 2003-02-15
SE8904239L (sv) 1991-06-16
HK1009290A1 (en) 1999-05-28
IE904510A1 (en) 1991-07-17
DE69032600T3 (de) 2006-07-20
EP0786474A1 (fr) 1997-07-30
NZ236276A (en) 1993-03-26
SE465222B (sv) 1991-08-12
AU7039391A (en) 1991-07-18
DK0506757T3 (da) 1999-05-25
SE465222C5 (sv) 1998-02-10
SG66753A1 (en) 2001-12-19
FI922745A0 (fi) 1992-06-12
FI104260B1 (fi) 1999-12-15
NL990035I1 (nl) 1999-12-01
ES2119769T3 (es) 1998-10-16
EP1293513A3 (fr) 2003-04-02
DE19975066I2 (de) 2005-07-07
BR9007921A (pt) 1992-11-10
NO309041B1 (no) 2000-12-04
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DE69032600T2 (de) 1999-01-07
JP2644084B2 (ja) 1997-08-25
EP0506757B1 (fr) 1998-08-26
HK1019449A1 (en) 2000-02-11
AU645539B2 (en) 1994-01-20
WO1991009122A1 (fr) 1991-06-27
SE8904239D0 (sv) 1989-12-15
EP0506757B2 (fr) 2005-10-26
DE69032600D1 (de) 1998-10-01
DK0786474T3 (da) 2003-03-03
EP0506757A1 (fr) 1992-10-07
EP0786474B1 (fr) 2003-02-05

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