DE69032600D1 - Rekombinanter abkömmling des menschlichen faktors iii - Google Patents

Rekombinanter abkömmling des menschlichen faktors iii

Info

Publication number
DE69032600D1
DE69032600D1 DE69032600T DE69032600T DE69032600D1 DE 69032600 D1 DE69032600 D1 DE 69032600D1 DE 69032600 T DE69032600 T DE 69032600T DE 69032600 T DE69032600 T DE 69032600T DE 69032600 D1 DE69032600 D1 DE 69032600D1
Authority
DE
Germany
Prior art keywords
human factor
factor viii
recombinant human
dna segment
segment coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69032600T
Other languages
English (en)
Other versions
DE69032600T3 (de
DE69032600T2 (de
Inventor
Anneli Almstedt
Eva Hellstroem
Kerstin Larsson
Peter Lind
Helena Sandberg
Jack Spira
Mona Sydow-Baeckman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Health AB
Original Assignee
Pharmacia and Upjohn AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20377785&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69032600(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia and Upjohn AB filed Critical Pharmacia and Upjohn AB
Publication of DE69032600D1 publication Critical patent/DE69032600D1/de
Application granted granted Critical
Publication of DE69032600T2 publication Critical patent/DE69032600T2/de
Publication of DE69032600T3 publication Critical patent/DE69032600T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Confectionery (AREA)
DE69032600T 1989-12-15 1990-12-06 Rekombinanter abkömmling des menschlichen faktors iii Expired - Lifetime DE69032600T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8904239 1989-12-15
SE8904239A SE465222C5 (sv) 1989-12-15 1989-12-15 Ett rekombinant, humant faktor VIII-derivat och förfarande för dess framställning
PCT/SE1990/000809 WO1991009122A1 (en) 1989-12-15 1990-12-06 A recombinant human factor viii derivative

Publications (3)

Publication Number Publication Date
DE69032600D1 true DE69032600D1 (de) 1998-10-01
DE69032600T2 DE69032600T2 (de) 1999-01-07
DE69032600T3 DE69032600T3 (de) 2006-07-20

Family

ID=20377785

Family Applications (3)

Application Number Title Priority Date Filing Date
DE1999175066 Active DE19975066I2 (de) 1989-12-15 1990-12-06 Rekombinanter Abk¦mmling des menschlichen Faktors III.
DE69034040T Expired - Lifetime DE69034040T2 (de) 1989-12-15 1990-12-06 Rekombinanter Abkömmling des menschlichen Faktors VIII
DE69032600T Expired - Lifetime DE69032600T3 (de) 1989-12-15 1990-12-06 Rekombinanter abkömmling des menschlichen faktors iii

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE1999175066 Active DE19975066I2 (de) 1989-12-15 1990-12-06 Rekombinanter Abk¦mmling des menschlichen Faktors III.
DE69034040T Expired - Lifetime DE69034040T2 (de) 1989-12-15 1990-12-06 Rekombinanter Abkömmling des menschlichen Faktors VIII

Country Status (21)

Country Link
EP (3) EP1293513A3 (de)
JP (1) JP2644084B2 (de)
AT (2) ATE232213T1 (de)
AU (1) AU645539B2 (de)
BR (1) BR9007921A (de)
CA (1) CA2071875C (de)
DE (3) DE19975066I2 (de)
DK (2) DK0786474T3 (de)
ES (2) ES2189897T3 (de)
FI (1) FI104260B1 (de)
HK (2) HK1009290A1 (de)
HU (1) HU211504A9 (de)
IE (1) IE904510A1 (de)
LU (1) LU90457I2 (de)
NL (1) NL990035I2 (de)
NO (1) NO309041B1 (de)
NZ (1) NZ236276A (de)
PT (1) PT96208B (de)
SE (1) SE465222C5 (de)
SG (1) SG66753A1 (de)
WO (1) WO1991009122A1 (de)

Families Citing this family (139)

* Cited by examiner, † Cited by third party
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US5744446A (en) * 1992-04-07 1998-04-28 Emory University Hybrid human/animal factor VIII
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SE9403915D0 (sv) * 1994-11-14 1994-11-14 Annelie Almstedt Process A
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SE9501189D0 (sv) * 1995-03-31 1995-03-31 Pharmacia Ab Protein formulation
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SE9503380D0 (sv) * 1995-09-29 1995-09-29 Pharmacia Ab Protein derivatives
US5851800A (en) * 1996-05-14 1998-12-22 Pharmacia & Upjohn Ab Process for producing a protein
EP1318198B1 (de) * 1996-05-14 2006-03-22 Biovitrum Ab Verfahren zur Herstellung eines rekombinanten Polypeptids unter Hinzufügung eines Chymotrypsinhemmstoffes zum Zellkulturmedium
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