ATE238345T1 - Protegrine - Google Patents
ProtegrineInfo
- Publication number
- ATE238345T1 ATE238345T1 AT96920452T AT96920452T ATE238345T1 AT E238345 T1 ATE238345 T1 AT E238345T1 AT 96920452 T AT96920452 T AT 96920452T AT 96920452 T AT96920452 T AT 96920452T AT E238345 T1 ATE238345 T1 AT E238345T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- basic
- independently
- present
- small amino
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Virology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Agronomy & Crop Science (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US45183295A | 1995-05-26 | 1995-05-26 | |
US08/499,523 US5804558A (en) | 1993-07-20 | 1995-07-07 | Protegrins |
PCT/US1996/007594 WO1996037508A1 (en) | 1995-05-26 | 1996-05-24 | Protegrins |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE238345T1 true ATE238345T1 (de) | 2003-05-15 |
Family
ID=27036536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96920452T ATE238345T1 (de) | 1995-05-26 | 1996-05-24 | Protegrine |
Country Status (9)
Country | Link |
---|---|
US (1) | US5804558A (de) |
EP (1) | EP0871654B1 (de) |
JP (1) | JPH11505721A (de) |
AT (1) | ATE238345T1 (de) |
AU (1) | AU716277B2 (de) |
CA (1) | CA2222475A1 (de) |
DE (1) | DE69627704T2 (de) |
ES (1) | ES2198488T3 (de) |
WO (1) | WO1996037508A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6159936A (en) * | 1993-07-20 | 2000-12-12 | The Regents Of The University Of California | Compositions and methods for treating and preventing microbial and viral infections |
US6653442B1 (en) | 1993-07-20 | 2003-11-25 | Intrabiotics Pharmaceuticals, Inc. | Protegrins |
USRE38828E1 (en) * | 1995-07-06 | 2005-10-11 | Intrabiotics Pharmaceuticals, Inc. | Parevins and tachytegrins |
US6307016B1 (en) | 1995-07-06 | 2001-10-23 | Intrabiotics Pharmaceuticals, Inc. | Parevins and tachytegrins |
US5994306A (en) * | 1995-11-22 | 1999-11-30 | Intrabiotics Pharmaceuticals, Inc. | Fine-tuned protegrins |
US5916872A (en) * | 1996-07-24 | 1999-06-29 | Intrabiotics Pharmaceuticals, Inc. | Cyclic peptides having broad spectrum antimicrobial activity |
CA2263164A1 (en) * | 1996-08-15 | 1998-02-19 | Southern Illinois University | Enhancement of antimicrobial peptide activity by metal ions |
AU6567098A (en) * | 1997-03-20 | 1998-10-12 | Regents Of The University Of California, The | Use of protegrins for periodontal indications |
FR2767323B1 (fr) * | 1997-08-12 | 2001-01-05 | Synt Em | Peptides lineaires derives de peptides antibiotiques, leur preparation et leur utilisation pour vectoriser des substances actives |
US6015941A (en) * | 1997-10-31 | 2000-01-18 | Pioneer Hi-Bred International, Inc. | Peptide derivatives of tachyplesin having antimicrobial activity |
US6043220A (en) * | 1997-12-03 | 2000-03-28 | Intrabiotics Pharmaceuticals, Inc. | Threonine-containing protegrins |
US6545140B1 (en) * | 1998-07-13 | 2003-04-08 | University Of Georgia Research Foundation, Inc. | DNA encoding an avian beta-defensin and uses thereof |
US6239113B1 (en) * | 1999-03-31 | 2001-05-29 | Insite Vision, Incorporated | Topical treatment or prevention of ocular infections |
US7056893B2 (en) * | 1999-03-31 | 2006-06-06 | Insite Vision, Inc. | Topical treatment for prevention of ocular infections |
US6335318B1 (en) | 1999-05-10 | 2002-01-01 | The Regents Of The University Of California | Antimicrobial theta defensins and methods of using same |
RU2172322C1 (ru) | 1999-12-27 | 2001-08-20 | Энтофарм Ко., Лтд. | Аллофероны-иммуномодулирующие пептиды |
FR2810985B1 (fr) * | 2000-07-03 | 2004-12-24 | Synt Em | Peptides lineaires amphipathiques et les compositions les contenant |
US6541222B1 (en) * | 2000-07-28 | 2003-04-01 | University Of Victoria Innovation And Development Corporation | Plant promoter isolated from Douglas-fir 2S seed storage protein gene |
US7314858B2 (en) * | 2001-04-18 | 2008-01-01 | The Regents Of The University Of California | Retrocyclins: antiviral and antimicrobial peptides |
US6713078B2 (en) | 2001-04-18 | 2004-03-30 | The Regents Of The University Of California | Retrocyclins: antiviral and antimicrobial peptides |
WO2003062266A2 (en) * | 2002-01-22 | 2003-07-31 | Intrabiotics Pharmaceuticals, Inc. | Hybrid synthetic method for antimicrobial peptides |
US7119070B2 (en) * | 2002-04-30 | 2006-10-10 | The Regents Of The University Of California | Antimicrobial theta defensins, analogs thereof, and methods of use |
US20060046970A1 (en) * | 2004-08-31 | 2006-03-02 | Insite Vision Incorporated | Topical otic compositions and methods of topical treatment of prevention of otic infections |
US20080255052A1 (en) * | 2004-12-23 | 2008-10-16 | The Regents Of The University Of California | Immunologic regulation by theta defensins |
JP5775260B2 (ja) | 2006-09-06 | 2015-09-09 | シー3 ジアン インコーポレイテッド | 選択的に標的化された抗菌性ペプチドおよびその使用 |
EP2300032A4 (de) | 2008-05-13 | 2012-12-05 | Univ Kansas | Metall-abstraktionspeptid (map)-tag und relevante verfahren |
WO2010033221A1 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of protegrin peptides |
WO2010033207A1 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of therapeutic peptides |
US20100202983A1 (en) * | 2009-02-09 | 2010-08-12 | Jernberg Gary R | Selectively targeted antimicrobials for the treatment of periodontal disease |
AU2013245805A1 (en) * | 2012-04-12 | 2014-10-30 | Stealth Peptides International, Inc. | Aromatic-cationic peptides and uses of same |
WO2013181461A2 (en) | 2012-06-01 | 2013-12-05 | University Of Kansas | Metal abstraction peptide with superoxide dismutase activity |
CN110114075B (zh) | 2016-11-09 | 2024-01-12 | 俄亥俄州国家创新基金会 | 含有二硫化物的细胞穿透肽及其制备和使用方法 |
WO2018098282A2 (en) * | 2016-11-22 | 2018-05-31 | Ohio State Innovation Foundation | Cyclic cell penetrating peptides comprising beta-hairpin motifs and methods of making and using thereof |
US10913773B2 (en) | 2016-11-22 | 2021-02-09 | Ohio State Innovation Foundation | Bicyclic peptidyl inhibitor of tumor necrosis factor-alpha |
WO2019217682A1 (en) | 2018-05-09 | 2019-11-14 | Ohio State Innovation Foundation | Cyclic cell-penetrating peptides with one or more hydrophobic residues |
CN111298101B (zh) * | 2020-02-21 | 2023-05-30 | 佛山科学技术学院 | 一种抗菌肽pg-1在抑制禽流感病毒中的应用 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4543252A (en) * | 1982-01-21 | 1985-09-24 | The Regents Of The University Of California | Cationic oligopeptides having microbicidal activity |
US4652639A (en) * | 1982-05-06 | 1987-03-24 | Amgen | Manufacture and expression of structural genes |
US4659692A (en) * | 1982-11-19 | 1987-04-21 | The Regents Of The University Of California | Cationic oligopeptides having microbicidal activity |
US4705777A (en) * | 1985-02-25 | 1987-11-10 | The Regents Of The University Of California | Cationic oligopeptides having microbicidal activity |
US5338724A (en) * | 1986-11-26 | 1994-08-16 | Cornell Research Foundation, Inc. | Antimicrobial proteins, compositions containing same and uses thereof |
US5126257A (en) * | 1986-11-26 | 1992-06-30 | Cornell Research Foundation | Antimicrobial proteins, compositions containing same and uses thereof |
US5087569A (en) * | 1986-11-26 | 1992-02-11 | Cornell Research Foundation, Inc. And The Rockefeller University | Antimicrobial proteins, compositions containing same and uses thereof |
US5032574A (en) * | 1988-05-26 | 1991-07-16 | Invitron Corporation | Novel antimicrobial peptide |
US5171739A (en) * | 1989-02-14 | 1992-12-15 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and preventation thereof using a BPI protein |
US5234912A (en) * | 1989-02-14 | 1993-08-10 | Incyte Pharmaceuticals, Inc. | Pharmaceutical compositions comprising recombinant BPI proteins and a lipid carrier and uses thereof |
US5334584A (en) * | 1989-02-14 | 1994-08-02 | Incyte Pharamaceuticals, Inc. | Recombinant, non-glycosylated bpi protein and uses thereof |
US5308834A (en) * | 1989-02-14 | 1994-05-03 | Incyte Pharmaceuticals, Inc. | Treatment of endotoxin-associated shock and prevention thereof using a BPI protein |
US5484885A (en) * | 1989-07-05 | 1996-01-16 | Emory University | Chemotactic, antibiotic and lipopolysaccharide-binding peptide fragments of CAP37 |
US5447914A (en) * | 1990-06-21 | 1995-09-05 | Emory University | Antimicrobial peptides |
US5432270A (en) * | 1990-10-25 | 1995-07-11 | Zasloff; Michael A. | DNA encoding tracheal antimicrobial peptides |
US5488035A (en) * | 1991-12-06 | 1996-01-30 | Pioneer Hi-Bred International, Inc. | Peptide with inhibitory activity towards plant pathogenic fungi |
US5422424A (en) * | 1992-05-26 | 1995-06-06 | The Regents Of The University Of California | Antibiotic cryptdin peptides and methods of their use |
ATE195954T1 (de) * | 1992-05-26 | 2000-09-15 | Univ California | Antibiotisches cryptdinpeptid und anwendungsmethoden |
US5459235A (en) * | 1993-03-19 | 1995-10-17 | The Regents Of The University Of California | Antimicrobial peptides antibodies and nucleic acid molecules from bovine neutrophils |
US5708145A (en) * | 1993-07-20 | 1998-01-13 | University Of California | Immunglobulins reactive with protegrins |
US5464823A (en) * | 1993-07-20 | 1995-11-07 | The Regents Of The University Of California | Mammalian antibiotic peptides |
AU682405B2 (en) * | 1993-10-14 | 1997-10-02 | Seikagaku Corporation | Polypeptide and anti-HIV agent prepared therefrom |
-
1995
- 1995-07-07 US US08/499,523 patent/US5804558A/en not_active Expired - Lifetime
-
1996
- 1996-05-24 EP EP96920452A patent/EP0871654B1/de not_active Expired - Lifetime
- 1996-05-24 JP JP8535883A patent/JPH11505721A/ja active Pending
- 1996-05-24 AT AT96920452T patent/ATE238345T1/de not_active IP Right Cessation
- 1996-05-24 CA CA002222475A patent/CA2222475A1/en not_active Abandoned
- 1996-05-24 DE DE69627704T patent/DE69627704T2/de not_active Expired - Fee Related
- 1996-05-24 WO PCT/US1996/007594 patent/WO1996037508A1/en active IP Right Grant
- 1996-05-24 ES ES96920452T patent/ES2198488T3/es not_active Expired - Lifetime
- 1996-05-24 AU AU58749/96A patent/AU716277B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
DE69627704T2 (de) | 2004-01-29 |
DE69627704D1 (en) | 2003-05-28 |
CA2222475A1 (en) | 1996-11-28 |
JPH11505721A (ja) | 1999-05-25 |
EP0871654A1 (de) | 1998-10-21 |
AU5874996A (en) | 1996-12-11 |
ES2198488T3 (es) | 2004-02-01 |
AU716277B2 (en) | 2000-02-24 |
WO1996037508A1 (en) | 1996-11-28 |
EP0871654A4 (de) | 2000-06-07 |
US5804558A (en) | 1998-09-08 |
EP0871654B1 (de) | 2003-04-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |