LT4550B - Dokozaheksaeno rūgšties ir dokozapentaeno rūgšties gavimo būdas - Google Patents
Dokozaheksaeno rūgšties ir dokozapentaeno rūgšties gavimo būdas Download PDFInfo
- Publication number
- LT4550B LT4550B LT99-005A LT99005A LT4550B LT 4550 B LT4550 B LT 4550B LT 99005 A LT99005 A LT 99005A LT 4550 B LT4550 B LT 4550B
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- Prior art keywords
- lipids
- acid
- dpr
- culture
- ulkenia
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
- C12P7/6434—Docosahexenoic acids [DHA]
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
- A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
- A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
- A23L33/12—Fatty acids or derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
- C11C1/00—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids
- C11C1/02—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils
- C11C1/04—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis
- C11C1/045—Preparation of fatty acids from fats, fatty oils, or waxes; Refining the fatty acids from fats or fatty oils by hydrolysis using enzymes or microorganisms, living or dead
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/12—Unicellular algae; Culture media therefor
- C12N1/125—Unicellular algae isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/145—Fungal isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6409—Fatty acids
- C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/6445—Glycerides
- C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/645—Fungi ; Processes using fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/89—Algae ; Processes using algae
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Botany (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Mycology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Nutrition Science (AREA)
- Animal Husbandry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP19351696 | 1996-07-23 |
Publications (2)
| Publication Number | Publication Date |
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| LT99005A LT99005A (en) | 1999-06-25 |
| LT4550B true LT4550B (lt) | 1999-10-25 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| LT99-005A LT4550B (lt) | 1996-07-23 | 1999-01-18 | Dokozaheksaeno rūgšties ir dokozapentaeno rūgšties gavimo būdas |
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| US (2) | US6509178B1 (et) |
| EP (3) | EP0935667B1 (et) |
| JP (2) | JP3343358B2 (et) |
| AT (2) | ATE347607T1 (et) |
| AU (1) | AU723553C (et) |
| BR (1) | BR9710394A (et) |
| CA (1) | CA2261231C (et) |
| CZ (2) | CZ300277B6 (et) |
| DE (2) | DE69739894D1 (et) |
| DK (2) | DK0935667T3 (et) |
| EE (1) | EE04063B1 (et) |
| ES (2) | ES2362476T3 (et) |
| HU (1) | HU229062B1 (et) |
| ID (1) | ID17466A (et) |
| IL (2) | IL128166A (et) |
| LT (1) | LT4550B (et) |
| LV (1) | LV12329B (et) |
| NO (2) | NO323173B1 (et) |
| PL (1) | PL193818B1 (et) |
| PT (2) | PT1785492E (et) |
| RU (1) | RU2226216C2 (et) |
| SI (1) | SI0935667T1 (et) |
| TR (1) | TR199900130T2 (et) |
| WO (1) | WO1998003671A1 (et) |
Families Citing this family (100)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340742A (en) * | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| US20060094089A1 (en) * | 1988-09-07 | 2006-05-04 | Martek Biosciences Corporation | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| EP0935667B1 (en) * | 1996-07-23 | 2006-12-06 | Nagase Chemtex Corporation | Process for preparing docosahexaenoic acid and docosapentaenoic acid |
| JP2001512029A (ja) * | 1997-08-01 | 2001-08-21 | マーテック・バイオサイエンスィズ・コーポレーション | Ｄｈａ含有栄養組成物およびそれらの製造方法 |
| JP4283351B2 (ja) * | 1998-08-27 | 2009-06-24 | サントリー酒類株式会社 | 新規な油脂組成物の製造方法および用途 |
| KR100504324B1 (ko) * | 1999-03-04 | 2005-07-28 | 산토리 가부시키가이샤 | 도코사펜타엔산 함유물질의 이용 |
| MX350779B (es) | 2000-01-19 | 2017-09-18 | Dsm Ip Assets B V * | Procedimiento de extraccion sin solvente. |
| AU2008229885B2 (en) * | 2000-01-19 | 2011-11-17 | Dsm Ip Assets B.V. | Solventless extraction process |
| EP1251744B2 (en) * | 2000-01-28 | 2015-08-26 | DSM IP Assets B.V. | Enhanced production of lipids containing polyenoic fatty acids by high density cultures of eukaryotic microbes in fermentors |
| DE60020271T2 (de) * | 2000-03-29 | 2006-03-23 | Council Of Scientific And Industrial Research | Verfahren zur erhöhung von mehrfachungesättigten fettsäuren in thraustochytriden |
| US6410282B1 (en) * | 2000-03-30 | 2002-06-25 | Council Of Scientific And Industrial Research | Method for enhancing levels of polyunsaturated fatty acids in thraustochytrid fungi |
| EP1178118A1 (en) | 2000-08-02 | 2002-02-06 | Dsm N.V. | Isolation of microbial oils |
| EP1322752B2 (en) | 2000-09-28 | 2015-02-11 | Bioriginal Food & Science Corp. | Fad4, fad5, fad5-2, and fad6, fatty acid desaturase family members and uses thereof |
| CA2469647C (en) | 2001-12-12 | 2011-02-15 | Daniel G. Dueppen | Extraction and winterization of lipids from oilseed and microbial sources |
| JP3840459B2 (ja) * | 2003-03-20 | 2006-11-01 | 裕司 島田 | グリセリドおよびその製造方法 |
| US8921422B2 (en) * | 2003-10-01 | 2014-12-30 | The Iams Company | Methods and kits for enhancing ability to learn in a puppy or kitten |
| KR101180594B1 (ko) * | 2003-10-02 | 2012-09-06 | 마텍 바이오싸이언스스 코포레이션 | 변형량의 염소 및 칼륨을 사용하는 미세조류 중에 고농도디에치에이의 생산 |
| DE10352838A1 (de) * | 2003-11-10 | 2005-07-07 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Verfahren zur Kultivierung von Mikroorganismen der Gattung Thraustochytriales unter Verwendung eines optimierten Niedrigsalzmediums |
| DE10352837A1 (de) * | 2003-11-10 | 2005-07-07 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Prozess zur Kultivierung von Mikroorganismen der Gattung Thraustochytriales |
| EP1537871A1 (en) * | 2003-12-04 | 2005-06-08 | Aventis Pharma S.A. | Enoxaparin for the treatment of cancer |
| DE102004017369A1 (de) | 2004-04-08 | 2005-11-03 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Screeningverfahren zur Identifizierung von PUFA-PKS in Proben |
| DE102004022015A1 (de) * | 2004-05-03 | 2005-12-01 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Fischfutter für Aquafarmen auf Basis fermentativ gewonnener mehrfach ungesättigter Fettsäuren |
| US7588931B2 (en) * | 2004-11-04 | 2009-09-15 | E. I. Du Pont De Nemours And Company | High arachidonic acid producing strains of Yarrowia lipolytica |
| DE102004062141A1 (de) * | 2004-12-23 | 2006-07-06 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Verfahren zur Herstellung eines Rohöls aus Gemischen von Mikroorganismen und Pflanzen, das so hergestellte Öl sowie die spezifischen Verwendungen des so hergestellten und gegebenenfalls zusätzlich raffinierten Öls |
| DE102005003624A1 (de) * | 2005-01-26 | 2006-07-27 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp. |
| DE102005003625A1 (de) * | 2005-01-26 | 2006-07-27 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Verfahren zur Herstellung einer DHA-haltigen Fettsäure-Zusammensetzung |
| PL1888081T3 (pl) * | 2005-05-23 | 2017-07-31 | Massachusetts Institute Of Technology | Kompozycje zawierające PUFA i sposoby ich zastosowania |
| PL2447356T3 (pl) | 2005-06-07 | 2016-10-31 | Mikroorganizmy eukariotyczne do wytwarzania lipidów i przeciwutleniaczy | |
| CN103211807A (zh) * | 2005-07-08 | 2013-07-24 | Dsmip资产公司 | 用于治疗痴呆和前痴呆相关病症的多不饱和脂肪酸 |
| WO2007035870A2 (en) * | 2005-09-20 | 2007-03-29 | Prolacta Bioscience, Inc. | A method for testing milk |
| DE102005054577A1 (de) | 2005-11-16 | 2007-05-24 | Cognis Ip Management Gmbh | Verwendung von Estern ungesättigter, physiologisch aktiver Fettsäuren als Nährmedien für Zellkulturen |
| ES2277557B1 (es) * | 2005-12-21 | 2008-07-01 | Proyecto Empresarial Brudy, S.L. | Utilizacion de acido docosahexaenoico para el tratamiento del daño celular oxidativo. |
| US9265745B2 (en) | 2005-12-21 | 2016-02-23 | Brudy Technology S.L. | Use of DHA, EPA or DHA-derived EPA for treating a pathology associated with cellular oxidative damage |
| EP1973406B1 (en) | 2005-12-28 | 2014-03-12 | Advanced Bionutrition Corporation | A delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form |
| US8968721B2 (en) | 2005-12-28 | 2015-03-03 | Advanced Bionutrition Corporation | Delivery vehicle for probiotic bacteria comprising a dry matrix of polysaccharides, saccharides and polyols in a glass form and methods of making same |
| BRPI0710665A2 (pt) * | 2006-04-03 | 2011-08-16 | Advanced Bionutrition Corp | formulações de ração contendo ácido docosa-hexaenóico |
| GB2437909A (en) * | 2006-05-12 | 2007-11-14 | Advanced Bionutrition Inc | Animal feed comprising docosahexaenois acid from a microbial source |
| EP1886680A1 (en) * | 2006-05-23 | 2008-02-13 | Nestec S.A. | Maternal supplement |
| CN101981201A (zh) * | 2006-08-01 | 2011-02-23 | 加拿大海洋营养食品有限公司 | 产油微生物及改良这些微生物的方法 |
| JP2010502189A (ja) * | 2006-08-29 | 2010-01-28 | マーテック バイオサイエンシーズ コーポレーション | 乳幼児用調合乳におけるＤＰＡ（ｎ−６）油の使用 |
| KR100684642B1 (ko) * | 2006-09-14 | 2007-02-22 | 주식회사 일신웰스 | 어유 유래 글리세라이드 유지 조성물 및 이의 제조방법 |
| WO2008049512A1 (en) * | 2006-10-27 | 2008-05-02 | Lonza Ag | Production of omega-3 fatty acids in microflora of thraustochytriales using modified media |
| CA2673120C (en) | 2006-12-18 | 2012-08-07 | Advanced Bionutrition Corporation | A dry food product containing live probiotic |
| US20080234377A1 (en) * | 2007-03-23 | 2008-09-25 | Martek Biosciences Corporation | Polyunsaturated fatty acids for treatment of dementia and pre-dementia-related conditions |
| AU2008269989B2 (en) * | 2007-06-29 | 2014-02-27 | Dsm Ip Assets B.V. | Production and purification of esters of polyunsaturated fatty acids |
| EP2071019A1 (en) | 2007-12-15 | 2009-06-17 | Lonza AG | Method for the cultivation of microoranisms of the order thraustochytriales |
| EP2105506A1 (de) | 2008-03-26 | 2009-09-30 | Lonza Ag | Verfahren zur Herstellung PUFAs enthaltender Öle unter Verwendung von Mikroorganismen der Ordnung Labyrinthulomycota |
| EP2145942A1 (de) * | 2008-07-15 | 2010-01-20 | Lonza Ltd. | Verfahren zur Isolierung von Ölen aus Zellen und Biomasse |
| US20100077654A1 (en) * | 2008-09-23 | 2010-04-01 | LiveFuels, Inc. | Systems and methods for producing biofuels from algae |
| CA2754952C (en) * | 2009-03-19 | 2018-11-06 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| US8207363B2 (en) | 2009-03-19 | 2012-06-26 | Martek Biosciences Corporation | Thraustochytrids, fatty acid compositions, and methods of making and uses thereof |
| ES2908047T3 (es) | 2009-03-27 | 2022-04-27 | Intervet Int Bv | Vacunas en micropartículas para la vacunación oral o nasal y el refuerzo de animales incluidos los peces |
| US8753851B2 (en) | 2009-04-17 | 2014-06-17 | LiveFuels, Inc. | Systems and methods for culturing algae with bivalves |
| NZ597053A (en) | 2009-05-26 | 2014-02-28 | Advanced Bionutrition Corp | Stable dry powder composition comprising biologically active microorganisms and/or bioactive materials and methods of making |
| WO2010147955A1 (en) * | 2009-06-16 | 2010-12-23 | LiveFuels, Inc. | Systems and methods for harvesting algae |
| CA2787344C (en) | 2010-01-19 | 2018-03-20 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| EP2529004B1 (en) | 2010-01-28 | 2017-06-07 | Advanced Bionutrition Corporation | Dry glassy composition comprising a bioactive material |
| US9504750B2 (en) | 2010-01-28 | 2016-11-29 | Advanced Bionutrition Corporation | Stabilizing composition for biological materials |
| WO2011133610A1 (en) | 2010-04-22 | 2011-10-27 | E. I. Du Pont De Nemours And Company | Method for obtaining polyunsaturated fatty acid-containing compositions from microbial biomass |
| EP2576801B1 (en) | 2010-06-01 | 2019-10-02 | DSM IP Assets B.V. | Extraction of lipid from cells and products therefrom |
| US20120204802A1 (en) | 2010-08-11 | 2012-08-16 | E. I. Du Pont De Nemours And Company | Sustainable aquaculture feeding strategy |
| US20120040076A1 (en) | 2010-08-11 | 2012-02-16 | E. I. Du Pont De Nemours And Company | Aquaculture feed compositions |
| US20120207912A1 (en) | 2010-08-11 | 2012-08-16 | E.I. Du Pont De Nemours And Company | Aquaculture meat products |
| RU2573324C2 (ru) | 2010-08-13 | 2016-01-20 | Эдванст Байоньютришн Корпорейшн | Стабилизирующая композиция для сухого хранения биологических материалов (варианты) |
| KR101115357B1 (ko) | 2010-09-03 | 2012-03-06 | 대상 주식회사 | 습식 상태의 미세조류로부터 조오일을 추출하는 방법 |
| US8973531B2 (en) * | 2010-12-09 | 2015-03-10 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Automated continuous zooplankton culture system |
| US9487716B2 (en) | 2011-05-06 | 2016-11-08 | LiveFuels, Inc. | Sourcing phosphorus and other nutrients from the ocean via ocean thermal energy conversion systems |
| US9222112B2 (en) | 2011-07-21 | 2015-12-29 | Dsm Ip Assets B.V. | Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof |
| WO2014074770A2 (en) | 2012-11-09 | 2014-05-15 | Heliae Development, Llc | Balanced mixotrophy methods |
| WO2014074772A1 (en) | 2012-11-09 | 2014-05-15 | Heliae Development, Llc | Mixotrophic, phototrophic, and heterotrophic combination methods and systems |
| WO2014096024A1 (de) * | 2012-12-19 | 2014-06-26 | Lonza Ltd | Verfahren zur herstellung einer lipid-reichen zusammensetzung aus mikroorganismen |
| CN105189740B (zh) | 2013-03-13 | 2019-01-15 | 帝斯曼营养品股份公司 | 工程化微生物 |
| FR3005860B1 (fr) * | 2013-05-21 | 2016-01-22 | Oreal | Compositions comprenant de l'huile d'ulkenia et leurs utilisations pour ameliorer et/ou renforcer la fonction barriere |
| FR3007652B1 (fr) * | 2013-06-28 | 2015-07-17 | Oreal | Composition comprenant de l'acide docosahexaenoique et du pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate |
| RU2537252C1 (ru) * | 2013-06-29 | 2014-12-27 | Федеральное государственное бюджетное учреждение науки Институт биологии моря им. А.В. Жирмунского Дальневосточного отделения Российской академии наук | Способ получения докозагексаеновой кислоты |
| EP2826384A1 (de) | 2013-07-16 | 2015-01-21 | Evonik Industries AG | Verfahren zur Trocknung von Biomasse |
| AR098890A1 (es) | 2013-12-20 | 2016-06-22 | Dsm Ip Assets Bv | Proceso para obtener aceite microbiano a partir de células microbianas |
| NZ721409A (en) | 2013-12-20 | 2022-10-28 | Dsm Ip Assets Bv | Processes for obtaining microbial oil from microbial cells |
| US11124736B2 (en) | 2013-12-20 | 2021-09-21 | Dsm Ip Assets B.V. | Processes for obtaining microbial oil from microbial cells |
| AR098896A1 (es) | 2013-12-20 | 2016-06-22 | Dsm Ip Assets Bv | Proceso para obtener aceite microbiano a partir de células microbianas |
| EP3083974A1 (en) | 2013-12-20 | 2016-10-26 | DSM Nutritional Products AG | Methods of recovering oil from microorganisms |
| KR102435269B1 (ko) | 2013-12-20 | 2022-08-22 | 디에스엠 아이피 어셋츠 비.브이. | 미생물 세포로부터의 미생물 오일의 수득 방법 |
| BR112016014262B1 (pt) | 2013-12-20 | 2022-04-05 | MARA Renewables Corporation | Método para recuperar lipídeos de uma população de micro-organismos |
| CZ307271B6 (cs) * | 2014-08-26 | 2018-05-09 | Vysoká škola chemicko - technologická v Praze | Způsob kultivace mořských protistů, zejména mikroorganismů rodu Thraustochytriales, na médiu obsahujícím odpadní solný roztok z demineralizace sladké mléčné syrovátky |
| WO2016050552A1 (de) | 2014-10-02 | 2016-04-07 | Evonik Degussa Gmbh | Verfahren zur herstellung einer pufas enthaltenden biomasse mit hoher zellstabilität |
| CA2958439C (en) | 2014-10-02 | 2022-09-20 | Evonik Industries Ag | Feedstuff of high abrasion resistance and good stability in water, containing pufas |
| CN106793803B (zh) | 2014-10-02 | 2021-03-09 | 赢创运营有限公司 | 通过挤压含pufa的生物质来制备含pufa的饲料的方法 |
| ES2900848T3 (es) | 2014-10-02 | 2022-03-18 | Evonik Operations Gmbh | Procedimiento para la producción de un pienso |
| AR104042A1 (es) | 2015-03-26 | 2017-06-21 | Mara Renewables Corp | Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto |
| KR102676949B1 (ko) | 2015-07-13 | 2024-06-19 | 마라 리뉴어블즈 코퍼레이션 | 크실로오스의 미세조류 대사를 강화시키는 방법 |
| WO2017019273A1 (en) | 2015-07-29 | 2017-02-02 | Advanced Bionutrition Corporation | Stable dry probiotic compositions for special dietary uses |
| WO2017094804A1 (ja) * | 2015-12-01 | 2017-06-08 | 日本水産株式会社 | ドコサヘキサエン酸含有油及びその製造方法 |
| US10851395B2 (en) | 2016-06-10 | 2020-12-01 | MARA Renewables Corporation | Method of making lipids with improved cold flow properties |
| JP6938163B2 (ja) * | 2017-02-06 | 2021-09-22 | 長瀬産業株式会社 | 脂質組成物、その用途及びその製造方法 |
| NL2019436B1 (en) | 2017-08-23 | 2019-03-07 | Newtricious Bv | Composition comprising a xantophyll and an omega-3 fatty acid and method of use thereof |
| JP7013416B2 (ja) * | 2018-06-21 | 2022-01-31 | マルハニチロ株式会社 | 腎機能維持及び保護剤、並びに、その効果評価方法 |
| GB2590868A (en) * | 2018-06-21 | 2021-07-07 | Maruha Nichiro Corp | Kidney function maintenance and protection agent, and method for evaluating effect thereof |
| FR3085962B1 (fr) | 2018-09-14 | 2021-06-18 | Fermentalg | Procede d'extracton d'une huile riche en pufa |
| US20220096416A1 (en) * | 2019-02-01 | 2022-03-31 | Mars, Incorporated | Feline food composition |
| WO2023140321A1 (ja) * | 2022-01-20 | 2023-07-27 | ホロバイオ株式会社 | 新規生物育種技術 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61204136A (ja) | 1985-03-06 | 1986-09-10 | Teijin Ltd | 血液脳関門通過性医薬品組成物 |
| JPH01199588A (ja) | 1987-10-27 | 1989-08-10 | Nitto Chem Ind Co Ltd | 糸状菌による高度不飽和脂肪酸の製造法 |
| JPH05503425A (ja) | 1990-02-13 | 1993-06-10 | マーテック・バイオサイエンスィズ・コーポレイション | ドコサヘキサエン酸含有油の製造法 |
| JPH05308978A (ja) | 1992-05-11 | 1993-11-22 | Onoda Cement Co Ltd | 藻類によるドコサヘキサエン酸の製造方法 |
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US161864A (en) * | 1875-04-13 | Improvement in methods of killing vermin | ||
| US539759A (en) * | 1895-05-21 | Laroy s | ||
| AU2122688A (en) | 1987-07-20 | 1989-02-13 | Maricultura, Incorporated | Microorganism production of omega-3 (n-3) lipids |
| US5130242A (en) | 1988-09-07 | 1992-07-14 | Phycotech, Inc. | Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids |
| WO1996033263A1 (fr) * | 1995-04-17 | 1996-10-24 | JAPAN, represented by DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY | Nouveaux micro-organismes capables de produire des acides gras hautement insatures et procede de production d'acides gras hautement insatures utilisant ces micro-organismes |
| JPH0930962A (ja) * | 1995-07-21 | 1997-02-04 | Nisshin Oil Mills Ltd:The | 医療用油脂含有組成物 |
| EP0935667B1 (en) | 1996-07-23 | 2006-12-06 | Nagase Chemtex Corporation | Process for preparing docosahexaenoic acid and docosapentaenoic acid |
-
1997
- 1997-06-06 EP EP97924346A patent/EP0935667B1/en not_active Expired - Lifetime
- 1997-06-06 CZ CZ0019999A patent/CZ300277B6/cs not_active IP Right Cessation
- 1997-06-06 CZ CZ20023236A patent/CZ299658B6/cs not_active IP Right Cessation
- 1997-06-06 HU HU9903703A patent/HU229062B1/hu not_active IP Right Cessation
- 1997-06-06 DK DK97924346T patent/DK0935667T3/da active
- 1997-06-06 SI SI9730759T patent/SI0935667T1/sl unknown
- 1997-06-06 IL IL128166A patent/IL128166A/en not_active IP Right Cessation
- 1997-06-06 JP JP50677698A patent/JP3343358B2/ja not_active Expired - Fee Related
- 1997-06-06 DE DE69739894T patent/DE69739894D1/de not_active Expired - Lifetime
- 1997-06-06 US US09/230,212 patent/US6509178B1/en not_active Expired - Lifetime
- 1997-06-06 AT AT97924346T patent/ATE347607T1/de active
- 1997-06-06 AU AU29798/97A patent/AU723553C/en not_active Ceased
- 1997-06-06 PT PT06022844T patent/PT1785492E/pt unknown
- 1997-06-06 EP EP06022844A patent/EP1785492B1/en not_active Expired - Lifetime
- 1997-06-06 PL PL97331326A patent/PL193818B1/pl unknown
- 1997-06-06 DE DE69737063T patent/DE69737063T2/de not_active Expired - Lifetime
- 1997-06-06 TR TR1999/00130T patent/TR199900130T2/xx unknown
- 1997-06-06 ES ES06022844T patent/ES2362476T3/es not_active Expired - Lifetime
- 1997-06-06 ES ES97924346T patent/ES2281913T3/es not_active Expired - Lifetime
- 1997-06-06 EE EEP199900026A patent/EE04063B1/et not_active IP Right Cessation
- 1997-06-06 DK DK06022844.2T patent/DK1785492T3/da active
- 1997-06-06 EP EP10160357A patent/EP2213750A1/en not_active Withdrawn
- 1997-06-06 WO PCT/JP1997/001946 patent/WO1998003671A1/en active IP Right Grant
- 1997-06-06 PT PT97924346T patent/PT935667E/pt unknown
- 1997-06-06 RU RU99103073/13A patent/RU2226216C2/ru not_active IP Right Cessation
- 1997-06-06 BR BR9710394-2A patent/BR9710394A/pt not_active Application Discontinuation
- 1997-06-06 CA CA2261231A patent/CA2261231C/en not_active Expired - Fee Related
- 1997-06-06 AT AT06022844T patent/ATE469244T1/de active
- 1997-07-23 ID IDP972549A patent/ID17466A/id unknown
-
1999
- 1999-01-18 LT LT99-005A patent/LT4550B/lt not_active IP Right Cessation
- 1999-01-21 NO NO19990270A patent/NO323173B1/no not_active IP Right Cessation
- 1999-02-23 LV LVP-99-12A patent/LV12329B/lv unknown
-
2002
- 2002-03-27 JP JP2002090053A patent/JP3538418B2/ja not_active Expired - Fee Related
-
2003
- 2003-01-13 US US10/341,300 patent/US7514244B2/en not_active Expired - Fee Related
-
2006
- 2006-09-05 NO NO20063977A patent/NO326902B1/no not_active IP Right Cessation
-
2007
- 2007-11-05 IL IL187179A patent/IL187179A0/en unknown
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61204136A (ja) | 1985-03-06 | 1986-09-10 | Teijin Ltd | 血液脳関門通過性医薬品組成物 |
| JPH01199588A (ja) | 1987-10-27 | 1989-08-10 | Nitto Chem Ind Co Ltd | 糸状菌による高度不飽和脂肪酸の製造法 |
| US5340742A (en) | 1988-09-07 | 1994-08-23 | Omegatech Inc. | Process for growing thraustochytrium and schizochytrium using non-chloride salts to produce a microfloral biomass having omega-3-highly unsaturated fatty acids |
| JPH05503425A (ja) | 1990-02-13 | 1993-06-10 | マーテック・バイオサイエンスィズ・コーポレイション | ドコサヘキサエン酸含有油の製造法 |
| JPH05308978A (ja) | 1992-05-11 | 1993-11-22 | Onoda Cement Co Ltd | 藻類によるドコサヘキサエン酸の製造方法 |
Non-Patent Citations (6)
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