LT3685B - Oxadiazolylalkylpurin derivatives, process for preparing them and pharmacological preparations - Google Patents

Oxadiazolylalkylpurin derivatives, process for preparing them and pharmacological preparations Download PDF

Info

Publication number
LT3685B
LT3685B LTIP1455A LTIP1455A LT3685B LT 3685 B LT3685 B LT 3685B LT IP1455 A LTIP1455 A LT IP1455A LT IP1455 A LTIP1455 A LT IP1455A LT 3685 B LT3685 B LT 3685B
Authority
LT
Lithuania
Prior art keywords
methyl
dihydro
dione
purine
oxadiazol
Prior art date
Application number
LTIP1455A
Other languages
English (en)
Lithuanian (lt)
Inventor
Dezso Korbonits
Emil Minker
Zoltan Vargai
Gergely Heja
Gabor Kovacs
Agnes Gottsegen
Sandor Antus
Sandor Virag
Andrea Bolehovszky
Jeno Marton
Katalin Marmarosi
Lorand Debreczeni
Laszlo Tardos
Peter Kormoczy
Vera Gergely
Gabor Horvath
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of LTIP1455A publication Critical patent/LTIP1455A/xx
Publication of LT3685B publication Critical patent/LT3685B/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • C07D473/06Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/04Drugs for disorders of the respiratory system for throat disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/14Antitussive agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
LTIP1455A 1986-10-09 1993-11-10 Oxadiazolylalkylpurin derivatives, process for preparing them and pharmacological preparations LT3685B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU864230A HU197574B (en) 1986-10-09 1986-10-09 Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances

Publications (2)

Publication Number Publication Date
LTIP1455A LTIP1455A (en) 1995-05-25
LT3685B true LT3685B (en) 1996-01-25

Family

ID=10967389

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1455A LT3685B (en) 1986-10-09 1993-11-10 Oxadiazolylalkylpurin derivatives, process for preparing them and pharmacological preparations

Country Status (28)

Country Link
US (1) US4840949A (ko)
EP (1) EP0264081B1 (ko)
JP (1) JPS63107980A (ko)
KR (1) KR960003612B1 (ko)
CN (1) CN1018644B (ko)
AT (1) ATE99685T1 (ko)
AU (1) AU595384B2 (ko)
BG (1) BG60403B2 (ko)
CS (1) CS276993B6 (ko)
CY (1) CY1843A (ko)
DD (1) DD262658A5 (ko)
DE (1) DE3788701D1 (ko)
DK (1) DK167806B1 (ko)
ES (1) ES2061465T3 (ko)
FI (1) FI87215C (ko)
GE (3) GEP19960657B (ko)
HK (1) HK78995A (ko)
HU (1) HU197574B (ko)
IL (1) IL84030A (ko)
LT (1) LT3685B (ko)
LV (1) LV10868B (ko)
NO (1) NO166323C (ko)
PL (2) PL268147A1 (ko)
RU (1) RU2007404C1 (ko)
SU (2) SU1602862A1 (ko)
UA (2) UA26368A (ko)
YU (1) YU47545B (ko)
ZA (1) ZA877333B (ko)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances
IT1199320B (it) * 1986-12-16 1988-12-30 Malesci Sas 8-azaxantine alchilaminoalchil o eterociclilalchil sostituite sul nucleo triazolico,loro sali fisiologicamente accettabili,loro composizioni farmaceutiche ad attivita'antibroncospastica e relativo procedimento di preparazione
HU198933B (en) * 1987-11-02 1989-12-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new xanthine derivatives and pharmaceutical compositions comprising same as active ingredient
HU206884B (en) * 1990-11-22 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing purin derivatives and pharmaceutical compositions containing them
HUP9700654A2 (hu) 1997-03-26 1999-09-28 Dezső Korbonits Teobromin tartalmú köhögéscsillapító készítmények
US7914828B2 (en) * 2008-10-17 2011-03-29 Levine Brian M Combination herbal product to benefit respiratory tract
US8106234B2 (en) * 2009-05-07 2012-01-31 OptMed, Inc Methylidene malonate process
US10414839B2 (en) 2010-10-20 2019-09-17 Sirrus, Inc. Polymers including a methylene beta-ketoester and products formed therefrom
US8361519B2 (en) 2010-11-18 2013-01-29 Aadvantics Pharmaceuticals, Inc. Combination herbal product to benefit respiratory tract in people exposed to smoke
EP3517523A1 (en) 2011-10-19 2019-07-31 Sirrus, Inc. Multifunctional monomers and methods for making them
EP2831124B1 (en) 2012-03-30 2016-10-05 Sirrus, Inc. Composite and laminate articles and polymerizable systems for producing the same
EP3626784A1 (en) 2012-03-30 2020-03-25 Sirrus, Inc. Ink and coating formulations and polymerizable systems for producing the same
WO2013181600A2 (en) 2012-06-01 2013-12-05 Bioformix Inc. Optical material and articles formed therefrom
WO2014078689A1 (en) 2012-11-16 2014-05-22 Bioformix Inc. Plastics bonding systems and methods
JP6549038B2 (ja) 2012-11-30 2019-07-24 シラス・インコーポレイテッド エレクトロニクス適用のための複合組成物
US9334430B1 (en) 2015-05-29 2016-05-10 Sirrus, Inc. Encapsulated polymerization initiators, polymerization systems and methods using the same
US9217098B1 (en) 2015-06-01 2015-12-22 Sirrus, Inc. Electroinitiated polymerization of compositions having a 1,1-disubstituted alkene compound
RU2754735C1 (ru) * 2020-12-14 2021-09-06 Федеральное государственное бюджетное образовательное учреждение высшего образования "Ярославский государственный технический университет" ФГБОУВО "ЯГТУ" Способ получения 3,5-дизамещенных 1,2,4-оксадиазолов, содержащих алкенильный фрагмент

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU190377B (en) * 1982-03-12 1986-08-28 Chinoin Gyogyszer Es Vegyeszet Process for preparing theophyllinyl-alkyl-oxadiazoles
HU197574B (en) * 1986-10-09 1989-04-28 Chinoin Gyogyszer Es Vegyeszet Process for production of derivatives of 3,7-dihydro-3-methil-7-//1,2,4-oxadiasole/-3-il/alkylenil/-1h-purin-2,6-dion and medical compositions containing these substances

Also Published As

Publication number Publication date
DD262658A5 (de) 1988-12-07
IL84030A0 (en) 1988-02-29
HK78995A (en) 1995-05-26
CS276993B6 (en) 1992-11-18
KR960003612B1 (ko) 1996-03-20
AU7946287A (en) 1988-04-14
DK527087D0 (da) 1987-10-08
DK527087A (da) 1988-04-10
BG60403B2 (bg) 1995-02-28
ES2061465T3 (es) 1994-12-16
FI874456A (fi) 1988-04-10
EP0264081A2 (de) 1988-04-20
NO874216D0 (no) 1987-10-08
EP0264081A3 (en) 1989-11-15
ATE99685T1 (de) 1994-01-15
CN1018644B (zh) 1992-10-14
FI87215B (fi) 1992-08-31
IL84030A (en) 1991-01-31
SU1635901A3 (ru) 1991-03-15
US4840949A (en) 1989-06-20
NO166323C (no) 1991-07-03
GEP19970842B (en) 1997-02-06
RU2007404C1 (ru) 1994-02-15
JPS63107980A (ja) 1988-05-12
ZA877333B (en) 1988-04-08
EP0264081B1 (de) 1994-01-05
FI87215C (fi) 1992-12-10
UA26368A (uk) 1999-08-30
FI874456A0 (fi) 1987-10-09
LV10868B (en) 1996-06-20
AU595384B2 (en) 1990-03-29
HU197574B (en) 1989-04-28
CN87107785A (zh) 1988-07-20
NO874216L (no) 1988-04-11
PL151206B1 (en) 1990-08-31
HUT46003A (en) 1988-09-28
YU47545B (sh) 1995-10-03
NO166323B (no) 1991-03-25
JPH0546348B2 (ko) 1993-07-13
SU1602862A1 (ru) 1990-10-30
PL268147A1 (en) 1988-09-01
CS732787A3 (en) 1992-04-15
DE3788701D1 (de) 1994-02-17
CY1843A (en) 1996-03-08
KR890006647A (ko) 1989-06-15
LTIP1455A (en) 1995-05-25
GEP19960657B (en) 1996-12-24
PL151110B1 (ko) 1990-08-31
DK167806B1 (da) 1993-12-20
LV10868A (lv) 1995-10-20
YU185787A (sh) 1993-05-28
UA5572A1 (uk) 1994-12-28
GEP19970817B (en) 1997-01-30

Similar Documents

Publication Publication Date Title
LT3685B (en) Oxadiazolylalkylpurin derivatives, process for preparing them and pharmacological preparations
JP2988739B2 (ja) 1,8−ナフチリジン−2−オン誘導体
JP2613352B2 (ja) パーキンソン病治療剤
PT92935B (pt) Processo para a preparacao de um composto de pirazolo-piridina e de composicoes farmaceuticas que o contem
JP2010077131A (ja) アゾリル基を有するキノリン誘導体およびキナゾリン誘導体
JP2023527997A (ja) Glp-1rアゴニストの塩及び結晶形態、並びにそれらの使用
KR20080038396A (ko) 선택적 hm74a 작동제로서의 크산틴 유도체
HU190377B (en) Process for preparing theophyllinyl-alkyl-oxadiazoles
US4960773A (en) Xanthine derivatives
WO2001083487A1 (fr) Derive de froindazole
KR20080015594A (ko) 포스포디에스테라제 저해제로서 유용한 퀴나졸린 유도체 및그 제조방법
US5010084A (en) Imidazoquinolone derivatives
EP0177965A2 (en) Novel oxa- and thiadiazolyl derivatives and their use
EP0588500A2 (en) 3-Oxadiazolyl-1,6-naphthyridine derivatives with affinity for benzodiazepine receptors
SI8711857A (sl) Derivati oksadiazol-alkil-purina
CA1288432C (en) Oxadiazole-alkyl-purine derivatives
CZ282155B6 (cs) Nové theofylinové deriváty, substituované v poloze -7 a způsob jejich výroby i použití
KR960004829B1 (ko) 1, 2-벤조티아진-1, 1-디옥사이드 유도체
JP2843671B2 (ja) キサンチン誘導体
JP2001302648A (ja) ピペラジン誘導体の製造法
JPH05262770A (ja) 化学的製法
CA2353897A1 (en) 1,4-benzodiazepinone derivatives and their use as integrin antagonists

Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 19981110