KR870001815B1 - 발효법에 의한 히알우론산의 제조방법 - Google Patents

발효법에 의한 히알우론산의 제조방법 Download PDF

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KR870001815B1
KR870001815B1 KR1019850003599A KR850003599A KR870001815B1 KR 870001815 B1 KR870001815 B1 KR 870001815B1 KR 1019850003599 A KR1019850003599 A KR 1019850003599A KR 850003599 A KR850003599 A KR 850003599A KR 870001815 B1 KR870001815 B1 KR 870001815B1
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South Korea
Prior art keywords
hyaluronic acid
culture
streptococcus
fermentation
strain
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Expired
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KR1019850003599A
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English (en)
Korean (ko)
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KR850007983A (ko
Inventor
히데미찌 아까사까
히사이우끼 코마사끼
타까이우끼 아라이
Original Assignee
가부시기가이샤 시세이도
오오노 요시오
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Publication of KR850007983A publication Critical patent/KR850007983A/ko
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Publication of KR870001815B1 publication Critical patent/KR870001815B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46—Streptococcus ; Enterococcus; Lactococcus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/885—Streptococcus

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
KR1019850003599A 1984-05-25 1985-05-24 발효법에 의한 히알우론산의 제조방법 Expired KR870001815B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59-105942 1984-05-25
JP59105942A JPS60251898A (ja) 1984-05-25 1984-05-25 醗酵法によるヒアルロン酸の製造方法

Publications (2)

Publication Number Publication Date
KR850007983A KR850007983A (ko) 1985-12-11
KR870001815B1 true KR870001815B1 (ko) 1987-10-13

Family

ID=14420898

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019850003599A Expired KR870001815B1 (ko) 1984-05-25 1985-05-24 발효법에 의한 히알우론산의 제조방법

Country Status (6)

Country Link
US (1) US4801539A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS60251898A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR870001815B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3517629A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2564859B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1183674B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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* Cited by examiner, † Cited by third party
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DE3531612A1 (de) * 1984-09-04 1986-03-27 Chisso Corp., Osaka Verfahren zur herstellung von hyaluronsaeure
AR241545A1 (es) * 1985-07-12 1992-08-31 Cornell Res Foundation Inc Un metodo para preparar una cepa de s. equi avirulenta a.t.c.c. 53186 para equinos.
JPS62215397A (ja) * 1986-03-17 1987-09-22 Nippon Kayaku Co Ltd ヒアルロン酸の製造方法
JPS62257382A (ja) * 1986-05-01 1987-11-09 Yakult Honsha Co Ltd 新規なストレプトコツカス・ズ−エピデミカス
JPS62257393A (ja) * 1986-05-01 1987-11-09 Yakult Honsha Co Ltd ヒアルロン酸の製造方法
US5023175A (en) * 1986-05-01 1991-06-11 Kabushiki Kaisha Yakult Honsha Novel production process of hyaluronic acid and bacterium strain therefor
JPS63156707A (ja) * 1986-12-19 1988-06-29 Yakult Honsha Co Ltd ヒアルロン酸含有化粧料
JPH0630604B2 (ja) * 1986-07-22 1994-04-27 電気化学工業株式会社 ヒアルロン酸の製造法
US4977082A (en) * 1987-12-10 1990-12-11 University Of Florida Research Foundation, Inc. Type VI bacterial FC receptors
JPH01265970A (ja) * 1988-04-19 1989-10-24 Shiseido Co Ltd ヒアルロン酸を含有させたコラーゲン水溶液又は水分散液
US4946780A (en) * 1988-10-12 1990-08-07 Denkl Kagaku Kogyo Kabushiki Kaisha Method for producing sodium hyaluronate by fermentation method
US4897349A (en) * 1989-04-28 1990-01-30 Medchem Products, Inc. Biosynthesis of hyaluronic acid
US5015577A (en) * 1989-08-29 1991-05-14 Board Of Regents, The University Of Texas System DNA encoding hyaluronate synthase
GB9024223D0 (en) * 1990-11-07 1990-12-19 Fermentech Ltd Production of hyaluronic acid
SE501217C2 (sv) * 1990-12-06 1994-12-12 Skandigen Ab Cellproliferationsmatris och användning därav
JPH0753117B2 (ja) * 1992-10-26 1995-06-07 チッソ株式会社 ヒアルロン酸の製造法
US6951743B2 (en) 1997-10-31 2005-10-04 University Of Oklahoma Board Of Regents Hyaluronan synthase genes and expression thereof in bacillus hosts
US6455304B1 (en) * 1994-07-01 2002-09-24 The Board Of Regents Of The University Of Oklahoma Hyaluronate synthase gene and uses thereof
US7091008B1 (en) * 1994-07-01 2006-08-15 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthase genes and expression thereof in Bacillus hosts
JP3799626B2 (ja) * 1995-04-25 2006-07-19 有限会社ナイセム 心臓血管修復材及びその製造方法
AU762036B2 (en) * 1997-10-31 2003-06-19 Board Of Regents Of The University Of Oklahoma, The Hyaluronan synthase gene and uses thereof
CN101113436B (zh) * 1997-10-31 2013-02-06 俄克拉何马大学董事会 透明质酸合酶基因及其应用
US7223571B2 (en) * 1998-04-02 2007-05-29 The Board Of Regents Of The Universtiy Of Oklahoma Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US6987023B2 (en) * 1998-04-02 2006-01-17 The Board Of Regents Of The University Of Oklahoma DNA encoding hyaluronan synthase from Pasteurella multocida and methods of use
US20060188966A1 (en) * 1998-04-02 2006-08-24 Deangelis Paul L Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same
US20080108110A1 (en) * 1998-04-02 2008-05-08 Deangelis Paul L Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same
US6630457B1 (en) 1998-09-18 2003-10-07 Orthogene Llc Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
US7094581B2 (en) * 1998-10-26 2006-08-22 The Board Of Regents Of The University Of Oklahoma Hyaluronan synthases and methods of making and using same
US20050287638A1 (en) * 2000-04-25 2005-12-29 Weigel Paul H Hyaluronan receptor for endocytosis, variants thereof, and methods of making and using same
US20070020737A1 (en) * 2001-12-03 2007-01-25 Pummill Philip E Hyaluronan synthases and methods of making and using same
IL162302A0 (en) 2001-12-21 2005-11-20 Novozymes Biopolymer As Methods for producing hyaluronan ina recombinant host cell
JP4816082B2 (ja) * 2003-07-31 2011-11-16 東洋紡績株式会社 ヒアルロン酸生産植物
US20050147715A1 (en) * 2003-12-17 2005-07-07 Novozymes Biopolymer A/S Dairy product comprising texturizers
US20050147732A1 (en) * 2003-12-17 2005-07-07 Novozymes Biopolymer A/S Method for preparing a food product comprising texturizers
EP1772052A1 (de) 2005-10-05 2007-04-11 Bayer CropScience GmbH Verbesserte Verfahren und Mittel zur Herstellung von Hyaluronan
CN101501075B (zh) 2006-08-04 2013-07-10 诺维信生物制药丹麦公司 支化透明质酸和制造方法
EP2036983A1 (de) * 2007-09-12 2009-03-18 Bayer CropScience AG Pflanzen, die erhöhte Mengen an Glucosaminglycanen synthetisieren
WO2009077399A1 (en) * 2007-12-19 2009-06-25 Evonik Goldschmidt Gmbh Crosslinked hyaluronic acid in emulsion
EP2213315A1 (en) 2009-01-30 2010-08-04 Mero S.r.L. Antibacterial hydrogel and use thereof in orthopedics
US9913810B2 (en) 2009-07-23 2018-03-13 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain using phospholipids and astaxanthin
US8481072B2 (en) * 2009-07-23 2013-07-09 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain
US8557275B2 (en) 2009-07-23 2013-10-15 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA
US9216164B2 (en) 2009-07-23 2015-12-22 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain using a mixture of fish oil and fish oil derived, choline based, phospholipid bound fatty acid mixture including polyunsaturated EPA and DHA
US9238043B2 (en) 2009-07-23 2016-01-19 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain using algae based oils
US9399047B2 (en) 2009-07-23 2016-07-26 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain using phospholipids and roe extract
US9402857B2 (en) 2009-07-23 2016-08-02 U.S. Nutraceuticals, LLC Composition and method to alleviate joint pain using low molecular weight hyaluronic acid and astaxanthin
US20110117207A1 (en) * 2009-11-17 2011-05-19 U.S. Nutraceuticals, LLC d/b/a Valensa International State of Incorporation: Use of eggshell membrane formulations to alleviate joint pain
IT1401498B1 (it) 2010-07-30 2013-07-26 Mero Srl Idrogelo a base di acido ialuronico e suo uso in ortopedia
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WO2014100837A1 (en) 2012-12-17 2014-06-26 Bui The Duy Computer aided implantation of body implants
KR102301455B1 (ko) * 2014-01-14 2021-09-10 큐피가부시키가이샤 히알루론산 및/또는 그 염 및 그 제조 방법, 그리고, 그 히알루론산 및/또는 그 염을 포함하는 식품, 화장료, 및 의약품
US9561095B1 (en) 2015-10-12 2017-02-07 Phi Nguyen Body augmentation device
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CN108410926B (zh) * 2017-12-03 2021-12-14 新疆阜丰生物科技有限公司 一种制备提取高分子量透明质酸的方法
WO2019158541A1 (en) 2018-02-14 2019-08-22 Frieslandcampina Nederland B.V. Nutritional compositions for musculoskeletal support for athletes
RU2719140C1 (ru) 2019-07-26 2020-04-17 Общество с ограниченной ответственностью "ЦЕНТР ТРАНСФЕРА БИОТЕХНОЛОГИЙ ОКА-Биотех" Бактерия рода bacillus, продуцирующая гиалуроновую кислоту, и способ получения гиалуроновой кислоты с использованием указанной бактерии
JP7727009B2 (ja) 2021-04-01 2025-08-20 ジボダン エス エー ヒアルロン酸を産生する組換え細胞
EP4174175A1 (en) 2021-10-26 2023-05-03 Givaudan SA Hyaluronic acid-producing recombinant cells
EP4067499A1 (en) 2021-04-01 2022-10-05 Givaudan SA Hyaluronic acid-producing recombinant cells
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EP4487863A1 (en) 2023-07-07 2025-01-08 NuPep AS Consensus peptides in hya for use in treating degenerated joints
EP4487834A1 (en) 2023-07-07 2025-01-08 NuPep AS Consensus peptides in hya
CN120230689B (zh) * 2025-06-03 2025-09-02 山东三元生物科技股份有限公司 马链球菌兽疫亚种及其应用和生产透明质酸的方法

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Also Published As

Publication number Publication date
DE3517629C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1987-09-03
IT1183674B (it) 1987-10-22
JPS60251898A (ja) 1985-12-12
DE3517629A1 (de) 1985-11-28
FR2564859B1 (fr) 1987-09-25
FR2564859A1 (fr) 1985-11-29
US4801539A (en) 1989-01-31
KR850007983A (ko) 1985-12-11
JPH0378116B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-12-12
IT8520869A0 (it) 1985-05-24

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