KR20190093816A - 지질 나노입자 mRNA 백신 - Google Patents
지질 나노입자 mRNA 백신Info
- Publication number
- KR20190093816A KR20190093816A KR1020197014650A KR20197014650A KR20190093816A KR 20190093816 A KR20190093816 A KR 20190093816A KR 1020197014650 A KR1020197014650 A KR 1020197014650A KR 20197014650 A KR20197014650 A KR 20197014650A KR 20190093816 A KR20190093816 A KR 20190093816A
- Authority
- KR
- South Korea
- Prior art keywords
- protein
- sequence
- mrna
- seq
- uniprotkb
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A61K31/16—Amides, e.g. hydroxamic acids
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- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/20—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
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- C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C219/04—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C219/06—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having the hydroxy groups esterified by carboxylic acids having the esterifying carboxyl groups bound to hydrogen atoms or to acyclic carbon atoms of an acyclic saturated carbon skeleton
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- C07C219/02—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
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- Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
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- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Medical Informatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020247032449A KR20240150810A (ko) | 2016-10-26 | 2017-10-26 | 지질 나노입자 mRNA 백신 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2016/075843 | 2016-10-26 | ||
| EP2016075843 | 2016-10-26 | ||
| EP2016075929 | 2016-10-27 | ||
| EPPCT/EP2016/075929 | 2016-10-27 | ||
| EP2017064066 | 2017-06-09 | ||
| EPPCT/EP2017/064066 | 2017-06-09 | ||
| PCT/EP2017/077517 WO2018078053A1 (en) | 2016-10-26 | 2017-10-26 | Lipid nanoparticle mrna vaccines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247032449A Division KR20240150810A (ko) | 2016-10-26 | 2017-10-26 | 지질 나노입자 mRNA 백신 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20190093816A true KR20190093816A (ko) | 2019-08-26 |
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197014650A Ceased KR20190093816A (ko) | 2016-10-26 | 2017-10-26 | 지질 나노입자 mRNA 백신 |
| KR1020247032449A Pending KR20240150810A (ko) | 2016-10-26 | 2017-10-26 | 지질 나노입자 mRNA 백신 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020247032449A Pending KR20240150810A (ko) | 2016-10-26 | 2017-10-26 | 지질 나노입자 mRNA 백신 |
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| EP (1) | EP3532094A1 (https=) |
| JP (3) | JP7289265B2 (https=) |
| KR (2) | KR20190093816A (https=) |
| CN (1) | CN110352071A (https=) |
| AU (3) | AU2017350488B2 (https=) |
| BR (1) | BR112019008481A2 (https=) |
| CA (1) | CA3040337A1 (https=) |
| IL (3) | IL301800B2 (https=) |
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| US12427204B2 (en) | 2022-01-28 | 2025-09-30 | Research & Business Foundation Sungkyunkwan University | Antibody-bound lipid nanoparticle comprising antibody bound to membrane scaffold protein |
| WO2024091037A1 (ko) * | 2022-10-27 | 2024-05-02 | 에스티팜 주식회사 | 폐를 표적장기로 하는 생분해성 지질나노입자 약물 전달 제형 및 이의 활용 |
| WO2024101618A1 (ko) * | 2022-11-08 | 2024-05-16 | 주식회사 삼양홀딩스 | 양이온성 지질 및 이의 제조방법 |
| WO2024106715A1 (ko) * | 2022-11-16 | 2024-05-23 | 주식회사 삼양홀딩스 | 양이온성 지질 및 이의 제조방법 |
| KR20250001443A (ko) | 2023-06-26 | 2025-01-06 | 주식회사 무진메디 | 이온화 가능한 펩타이드를 이용한 지질 나노입자 기반 약물 전달체 및 이의 제조방법 |
| WO2025084582A1 (ko) * | 2023-10-19 | 2025-04-24 | 주식회사 삼양홀딩스 | 양이온성 지질 및 이의 제조방법 |
| WO2025143853A1 (ko) * | 2023-12-29 | 2025-07-03 | 주식회사 삼양홀딩스 | 약물전달용 나노입자의 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20240150810A (ko) | 2024-10-16 |
| MX2019004913A (es) | 2019-09-16 |
| CN110352071A (zh) | 2019-10-18 |
| US20200163878A1 (en) | 2020-05-28 |
| JP2026004487A (ja) | 2026-01-14 |
| JP7754880B2 (ja) | 2025-10-15 |
| MX2024009845A (es) | 2024-08-22 |
| CA3040337A1 (en) | 2018-05-03 |
| IL266194B1 (en) | 2023-05-01 |
| US20260090989A1 (en) | 2026-04-02 |
| IL301800B1 (en) | 2025-01-01 |
| IL301800A (en) | 2023-05-01 |
| JP7289265B2 (ja) | 2023-06-09 |
| AU2022235588A1 (en) | 2023-03-02 |
| IL266194A (en) | 2019-06-30 |
| BR112019008481A2 (pt) | 2020-03-03 |
| AU2017350488B2 (en) | 2022-06-23 |
| AU2025201944A1 (en) | 2025-04-03 |
| IL301800B2 (en) | 2025-05-01 |
| IL317855A (en) | 2025-02-01 |
| JP2023109965A (ja) | 2023-08-08 |
| JP2020504764A (ja) | 2020-02-13 |
| SG11201903460QA (en) | 2019-05-30 |
| AU2017350488A1 (en) | 2019-05-02 |
| AU2022235588B2 (en) | 2024-12-19 |
| WO2018078053A1 (en) | 2018-05-03 |
| US20250288522A1 (en) | 2025-09-18 |
| EP3532094A1 (en) | 2019-09-04 |
| US20210251898A1 (en) | 2021-08-19 |
| IL266194B2 (en) | 2023-09-01 |
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