KR19990021832A - 폴리실록산-폴리올 마크로머, 이의 제조방법 및 이의 용도 - Google Patents
폴리실록산-폴리올 마크로머, 이의 제조방법 및 이의 용도 Download PDFInfo
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- KR19990021832A KR19990021832A KR1019970708306A KR19970708306A KR19990021832A KR 19990021832 A KR19990021832 A KR 19990021832A KR 1019970708306 A KR1019970708306 A KR 1019970708306A KR 19970708306 A KR19970708306 A KR 19970708306A KR 19990021832 A KR19990021832 A KR 19990021832A
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- 239000007943 implant Substances 0.000 claims abstract description 41
- 238000006116 polymerization reaction Methods 0.000 claims abstract description 24
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- 230000008569 process Effects 0.000 claims abstract description 15
- 238000000576 coating method Methods 0.000 claims abstract description 13
- 239000011248 coating agent Substances 0.000 claims abstract description 11
- 125000002348 vinylic group Chemical group 0.000 claims abstract description 8
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- 150000001735 carboxylic acids Chemical class 0.000 claims description 5
- 235000012209 glucono delta-lactone Nutrition 0.000 claims description 5
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- DVKJHBMWWAPEIU-UHFFFAOYSA-N toluene 2,4-diisocyanate Chemical compound CC1=CC=C(N=C=O)C=C1N=C=O DVKJHBMWWAPEIU-UHFFFAOYSA-N 0.000 claims description 5
- 229960000834 vinyl ether Drugs 0.000 claims description 5
- QRFNDAVXJCGLFB-GJPGBQJBSA-N (3r,3ar,6s,6ar)-3,6-dihydroxy-3,3a,6,6a-tetrahydrofuro[3,2-b]furan-2,5-dione Chemical compound O1C(=O)[C@H](O)[C@H]2OC(=O)[C@@H](O)[C@H]21 QRFNDAVXJCGLFB-GJPGBQJBSA-N 0.000 claims description 4
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 4
- 150000001336 alkenes Chemical class 0.000 claims description 4
- 125000005024 alkenyl aryl group Chemical group 0.000 claims description 4
- 125000005250 alkyl acrylate group Chemical group 0.000 claims description 4
- 230000001588 bifunctional effect Effects 0.000 claims description 4
- IISBACLAFKSPIT-UHFFFAOYSA-N bisphenol A Chemical compound C=1C=C(O)C=CC=1C(C)(C)C1=CC=C(O)C=C1 IISBACLAFKSPIT-UHFFFAOYSA-N 0.000 claims description 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 4
- 230000010261 cell growth Effects 0.000 claims description 4
- 125000005442 diisocyanate group Chemical group 0.000 claims description 4
- LYCAIKOWRPUZTN-UHFFFAOYSA-N ethylene glycol Natural products OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims description 4
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 claims description 4
- NIMLQBUJDJZYEJ-UHFFFAOYSA-N isophorone diisocyanate Chemical compound CC1(C)CC(N=C=O)CC(C)(CN=C=O)C1 NIMLQBUJDJZYEJ-UHFFFAOYSA-N 0.000 claims description 4
- FQPSGWSUVKBHSU-UHFFFAOYSA-N methacrylamide Chemical compound CC(=C)C(N)=O FQPSGWSUVKBHSU-UHFFFAOYSA-N 0.000 claims description 4
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- SNOOUWRIMMFWNE-UHFFFAOYSA-M sodium;6-[(3,4,5-trimethoxybenzoyl)amino]hexanoate Chemical compound [Na+].COC1=CC(C(=O)NCCCCCC([O-])=O)=CC(OC)=C1OC SNOOUWRIMMFWNE-UHFFFAOYSA-M 0.000 claims description 4
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 4
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- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 claims description 3
- KGIGUEBEKRSTEW-UHFFFAOYSA-N 2-vinylpyridine Chemical compound C=CC1=CC=CC=N1 KGIGUEBEKRSTEW-UHFFFAOYSA-N 0.000 claims description 3
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 claims description 3
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 3
- 125000005587 carbonate group Chemical group 0.000 claims description 3
- 150000004676 glycans Chemical class 0.000 claims description 3
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- 239000003446 ligand Substances 0.000 claims description 3
- 150000004044 tetrasaccharides Chemical class 0.000 claims description 3
- WVAFEFUPWRPQSY-UHFFFAOYSA-N 1,2,3-tris(ethenyl)benzene Chemical compound C=CC1=CC=CC(C=C)=C1C=C WVAFEFUPWRPQSY-UHFFFAOYSA-N 0.000 claims description 2
- OVBFMUAFNIIQAL-UHFFFAOYSA-N 1,4-diisocyanatobutane Chemical compound O=C=NCCCCN=C=O OVBFMUAFNIIQAL-UHFFFAOYSA-N 0.000 claims description 2
- CDMDQYCEEKCBGR-UHFFFAOYSA-N 1,4-diisocyanatocyclohexane Chemical compound O=C=NC1CCC(N=C=O)CC1 CDMDQYCEEKCBGR-UHFFFAOYSA-N 0.000 claims description 2
- ATOUXIOKEJWULN-UHFFFAOYSA-N 1,6-diisocyanato-2,2,4-trimethylhexane Chemical compound O=C=NCCC(C)CC(C)(C)CN=C=O ATOUXIOKEJWULN-UHFFFAOYSA-N 0.000 claims description 2
- CTXUTPWZJZHRJC-UHFFFAOYSA-N 1-ethenylpyrrole Chemical compound C=CN1C=CC=C1 CTXUTPWZJZHRJC-UHFFFAOYSA-N 0.000 claims description 2
- GNEPBTGCKNEPNE-UHFFFAOYSA-N 1-isocyanatoprop-2-enylbenzene Chemical compound O=C=NC(C=C)C1=CC=CC=C1 GNEPBTGCKNEPNE-UHFFFAOYSA-N 0.000 claims description 2
- KGRVJHAUYBGFFP-UHFFFAOYSA-N 2,2'-Methylenebis(4-methyl-6-tert-butylphenol) Chemical compound CC(C)(C)C1=CC(C)=CC(CC=2C(=C(C=C(C)C=2)C(C)(C)C)O)=C1O KGRVJHAUYBGFFP-UHFFFAOYSA-N 0.000 claims description 2
- 229920000536 2-Acrylamido-2-methylpropane sulfonic acid Polymers 0.000 claims description 2
- XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 claims description 2
- BQBSIHIZDSHADD-UHFFFAOYSA-N 2-ethenyl-4,5-dihydro-1,3-oxazole Chemical compound C=CC1=NCCO1 BQBSIHIZDSHADD-UHFFFAOYSA-N 0.000 claims description 2
- KFDVPJUYSDEJTH-UHFFFAOYSA-N 4-ethenylpyridine Chemical compound C=CC1=CC=NC=C1 KFDVPJUYSDEJTH-UHFFFAOYSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
- FBPFZTCFMRRESA-ZXXMMSQZSA-N D-iditol Chemical compound OC[C@@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-ZXXMMSQZSA-N 0.000 claims description 2
- KXTCDGRHGVMZOH-SLVMBWJPSA-N D-maltoheptaono-1,5-lactone Chemical compound OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O[C@H]5[C@H](O)[C@@H](O)[C@@H](O[C@H]6[C@H](O)[C@@H](O)[C@@H](O[C@H]7[C@H](O)[C@@H](O)C(=O)O[C@@H]7CO)O[C@@H]6CO)O[C@@H]5CO)O[C@@H]4CO)O[C@@H]3CO)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O KXTCDGRHGVMZOH-SLVMBWJPSA-N 0.000 claims description 2
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- 125000005907 alkyl ester group Chemical group 0.000 claims description 2
- 150000004808 allyl alcohols Chemical class 0.000 claims description 2
- HXBPYFMVGFDZFT-UHFFFAOYSA-N allyl isocyanate Chemical compound C=CCN=C=O HXBPYFMVGFDZFT-UHFFFAOYSA-N 0.000 claims description 2
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- QUDWYFHPNIMBFC-UHFFFAOYSA-N bis(prop-2-enyl) benzene-1,2-dicarboxylate Chemical compound C=CCOC(=O)C1=CC=CC=C1C(=O)OCC=C QUDWYFHPNIMBFC-UHFFFAOYSA-N 0.000 claims description 2
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- AFOSIXZFDONLBT-UHFFFAOYSA-N divinyl sulfone Chemical compound C=CS(=O)(=O)C=C AFOSIXZFDONLBT-UHFFFAOYSA-N 0.000 claims description 2
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- RRAMGCGOFNQTLD-UHFFFAOYSA-N hexamethylene diisocyanate Chemical compound O=C=NCCCCCCN=C=O RRAMGCGOFNQTLD-UHFFFAOYSA-N 0.000 claims description 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 2
- WARQUFORVQESFF-UHFFFAOYSA-N isocyanatoethene Chemical compound C=CN=C=O WARQUFORVQESFF-UHFFFAOYSA-N 0.000 claims description 2
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- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Landscapes
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1496/95 | 1995-05-19 | ||
| CH149695 | 1995-05-19 | ||
| US8/569816 | 1995-12-08 | ||
| US08569816 US5760100B1 (en) | 1994-09-06 | 1995-12-08 | Extended wear ophthalmic lens |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR19990021832A true KR19990021832A (ko) | 1999-03-25 |
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| Application Number | Title | Priority Date | Filing Date |
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| KR1019970708306A Withdrawn KR19990021832A (ko) | 1995-05-19 | 1996-05-07 | 폴리실록산-폴리올 마크로머, 이의 제조방법 및 이의 용도 |
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| EP (1) | EP0826158B1 (enExample) |
| JP (2) | JP5048173B2 (enExample) |
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| SI (1) | SI0819258T1 (enExample) |
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Families Citing this family (127)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6357854A (ja) * | 1986-08-29 | 1988-03-12 | Aisin Seiki Co Ltd | スタ−リング機関の作動ガス圧力制御装置 |
| US5760100B1 (en) | 1994-09-06 | 2000-11-14 | Ciba Vision Corp | Extended wear ophthalmic lens |
| US7468398B2 (en) | 1994-09-06 | 2008-12-23 | Ciba Vision Corporation | Extended wear ophthalmic lens |
| US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
| US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
| US6200626B1 (en) * | 1999-05-20 | 2001-03-13 | Bausch & Lomb Incorporated | Surface-treatment of silicone medical devices comprising an intermediate carbon coating and graft polymerization |
| KR100703583B1 (ko) * | 1999-10-07 | 2007-04-05 | 존슨 앤드 존슨 비젼 케어, 인코포레이티드 | 실리콘 하이드로겔, 이의 제조방법 및 이를 포함하는 콘택트 렌즈 |
| JP2001163933A (ja) * | 1999-10-27 | 2001-06-19 | Novartis Ag | 材料表面を改質する方法 |
| US7521519B1 (en) * | 2000-03-14 | 2009-04-21 | Novartis Ag | Organic compounds |
| US6770721B1 (en) | 2000-11-02 | 2004-08-03 | Surface Logix, Inc. | Polymer gel contact masks and methods and molds for making same |
| WO2002052045A1 (en) * | 2000-12-26 | 2002-07-04 | Aviva Biosciences | Active and biocompatible platforms prepared by polymerization of surface coating films |
| US20050276858A1 (en) * | 2001-04-23 | 2005-12-15 | Kao Weiyuan J | Bifunctional-modified hydrogels |
| EP1423093A4 (en) | 2001-04-23 | 2005-11-30 | Wisconsin Alumni Res Found | BIFUNCTIONAL MODIFIED HYDROGEL |
| US20030032874A1 (en) * | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
| US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
| US7226978B2 (en) * | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
| US7163292B2 (en) * | 2002-09-06 | 2007-01-16 | Synergeyes, Inc. | Hybrid contact lens system and method |
| EP1546984A1 (en) * | 2002-09-06 | 2005-06-29 | Quarter Lambda Technologies Inc. | Hybrid contact lens system and method |
| US7322694B2 (en) * | 2002-09-06 | 2008-01-29 | Synergeyes, Inc. | Hybrid contact lens system and method |
| US7104648B2 (en) * | 2002-09-06 | 2006-09-12 | Synergeyes, Inc. | Hybrid contact lens system and method |
| JP4708342B2 (ja) | 2003-07-25 | 2011-06-22 | デックスコム・インコーポレーテッド | 埋設可能な装置に用いる酸素増大膜システム |
| US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
| US9135402B2 (en) | 2007-12-17 | 2015-09-15 | Dexcom, Inc. | Systems and methods for processing sensor data |
| US7591801B2 (en) | 2004-02-26 | 2009-09-22 | Dexcom, Inc. | Integrated delivery device for continuous glucose sensor |
| US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
| US20050090607A1 (en) * | 2003-10-28 | 2005-04-28 | Dexcom, Inc. | Silicone composition for biocompatible membrane |
| US7109280B2 (en) * | 2003-10-29 | 2006-09-19 | Council Of Scientific And Industrial Research | Block copolymers and preparation thereof |
| US20050096446A1 (en) * | 2003-10-29 | 2005-05-05 | Council Of Scientific And Industrial | Tri-block copolymers and a process for the preparation of the same |
| US7018039B2 (en) | 2003-11-14 | 2006-03-28 | Synergeyes,Inc. | Contact lens |
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- 1996-03-22 SI SI9630391T patent/SI0819258T1/xx unknown
- 1996-03-22 DE DE29624309U patent/DE29624309U1/de not_active Expired - Lifetime
- 1996-04-02 AR AR33601496A patent/AR001497A1/es unknown
- 1996-05-07 KR KR1019970708306A patent/KR19990021832A/ko not_active Withdrawn
- 1996-05-07 AT AT96919684T patent/ATE184708T1/de not_active IP Right Cessation
- 1996-05-07 CZ CZ973639A patent/CZ363997A3/cs unknown
- 1996-05-07 JP JP53451396A patent/JP5048173B2/ja not_active Expired - Fee Related
- 1996-05-07 US US08/952,416 patent/US6043328A/en not_active Expired - Lifetime
- 1996-05-07 BR BR9608824A patent/BR9608824A/pt not_active Application Discontinuation
- 1996-05-07 HU HU9801139A patent/HUP9801139A3/hu unknown
- 1996-05-07 AU AU58144/96A patent/AU5814496A/en not_active Abandoned
- 1996-05-07 WO PCT/EP1996/001888 patent/WO1996036890A1/en not_active Ceased
- 1996-05-07 CN CN96194388A patent/CN1186550A/zh active Pending
- 1996-05-07 EP EP96919684A patent/EP0826158B1/en not_active Expired - Lifetime
- 1996-05-07 PL PL96323350A patent/PL323350A1/xx unknown
- 1996-05-07 DE DE69604285T patent/DE69604285T2/de not_active Expired - Lifetime
- 1996-05-07 CA CA002220217A patent/CA2220217A1/en not_active Abandoned
- 1996-05-13 IL IL11823796A patent/IL118237A0/xx unknown
- 1996-05-17 ZA ZA963937A patent/ZA963937B/xx unknown
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1997
- 1997-11-18 NO NO975289A patent/NO975289L/no unknown
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2011
- 2011-05-18 JP JP2011111611A patent/JP2011225884A/ja active Pending
Also Published As
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| JPH11505564A (ja) | 1999-05-21 |
| DE69604285D1 (de) | 1999-10-21 |
| CA2220217A1 (en) | 1996-11-21 |
| BR9608824A (pt) | 1999-06-15 |
| WO1996036890A1 (en) | 1996-11-21 |
| MX9708910A (es) | 1998-03-31 |
| HUP9801139A3 (en) | 1998-10-28 |
| CN1186550A (zh) | 1998-07-01 |
| NO975289L (no) | 1998-01-16 |
| ZA963937B (en) | 1997-01-06 |
| DE29624309U1 (de) | 2002-01-03 |
| EP0826158B1 (en) | 1999-09-15 |
| JP2011225884A (ja) | 2011-11-10 |
| JP5048173B2 (ja) | 2012-10-17 |
| ATE184708T1 (de) | 1999-10-15 |
| NO975289D0 (no) | 1997-11-18 |
| EP0826158A1 (en) | 1998-03-04 |
| AU5814496A (en) | 1996-11-29 |
| PL323350A1 (en) | 1998-03-30 |
| DE69604285T2 (de) | 2000-03-23 |
| AR001497A1 (es) | 1997-10-22 |
| CZ363997A3 (cs) | 1998-03-18 |
| US6043328A (en) | 2000-03-28 |
| IL118237A0 (en) | 1996-09-12 |
| SI0819258T1 (en) | 2002-04-30 |
| HUP9801139A2 (hu) | 1998-09-28 |
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