SG10201901379TA - Method for applying stable coating on silicone hydrogel contact lenses - Google Patents

Method for applying stable coating on silicone hydrogel contact lenses

Info

Publication number
SG10201901379TA
SG10201901379TA SG10201901379TA SG10201901379TA SG10201901379TA SG 10201901379T A SG10201901379T A SG 10201901379TA SG 10201901379T A SG10201901379T A SG 10201901379TA SG 10201901379T A SG10201901379T A SG 10201901379TA SG 10201901379T A SG10201901379T A SG 10201901379TA
Authority
SG
Singapore
Prior art keywords
silicone hydrogel
hydrogel contact
contact lenses
stable coating
coating
Prior art date
Application number
SG10201901379TA
Inventor
Steve Yun Zhang
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of SG10201901379TA publication Critical patent/SG10201901379TA/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04—Coating
    • C08J7/043—Improving the adhesiveness of the coatings per se, e.g. forming primers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D3/00—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
    • B05D3/04—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to gases
    • B05D3/0466—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to gases the gas being a non-reacting gas
    • B05D3/0473—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by exposure to gases the gas being a non-reacting gas for heating, e.g. vapour heating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D5/00—Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
    • B05D7/02—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to macromolecular substances, e.g. rubber
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
    • B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
    • B05D7/50—Multilayers
    • B05D7/56—Three layers or more
    • B05D7/57—Three layers or more the last layer being a clear coat
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/00009—Production of simple or compound lenses
    • B29D11/00038—Production of contact lenses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/00009—Production of simple or compound lenses
    • B29D11/00038—Production of contact lenses
    • B29D11/00048—Production of contact lenses composed of parts with dissimilar composition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/00865—Applying coatings; tinting; colouring
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04—Coating
    • C08J7/0427—Coating with only one layer of a composition containing a polymer binder
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/04—Coating
    • C08J7/056—Forming hydrophilic coatings
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/08—Heat treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
    • C08J7/12—Chemical modification
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/041—Lenses
    • G02B1/043—Contact lenses
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/10—Optical coatings produced by application to, or surface treatment of, optical elements
    • G02B1/18—Coatings for keeping optical surfaces clean, e.g. hydrophobic or photo-catalytic films
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2333/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2333/24—Homopolymers or copolymers of amides or imides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2339/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a single or double bond to nitrogen or by a heterocyclic ring containing nitrogen; Derivatives of such polymers
    • C08J2339/04—Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
    • C08J2339/06—Homopolymers or copolymers of N-vinyl-pyrrolidones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2433/00—Characterised by the use of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides, or nitriles thereof; Derivatives of such polymers
    • C08J2433/02—Homopolymers or copolymers of acids; Metal or ammonium salts thereof

Abstract

Method for Applying Stable Coating on Silicone Hydrogel Contact Lenses The invention is related to a method for producing silicone hydrogel contact lenses with having a stable coating thereon. A method of the invention comprises a water-based coating process (step) for forming a relatively-stable base coating of a homo- or copolymer of acrylic acid or C 1-C3 alkylacrylic acid onto a silicone hydrogel contact lens made from a lens formulation comprising from about 35% to about 60% by weight of N-vinylpyrrolidone.
SG10201901379TA 2014-08-26 2015-08-24 Method for applying stable coating on silicone hydrogel contact lenses SG10201901379TA (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462041771P 2014-08-26 2014-08-26

Publications (1)

Publication Number Publication Date
SG10201901379TA true SG10201901379TA (en) 2019-03-28

Family

ID=54072987

Family Applications (2)

Application Number Title Priority Date Filing Date
SG10201901379TA SG10201901379TA (en) 2014-08-26 2015-08-24 Method for applying stable coating on silicone hydrogel contact lenses
SG11201700232SA SG11201700232SA (en) 2014-08-26 2015-08-24 Method for applying stable coating on silicone hydrogel contact lenses

Family Applications After (1)

Application Number Title Priority Date Filing Date
SG11201700232SA SG11201700232SA (en) 2014-08-26 2015-08-24 Method for applying stable coating on silicone hydrogel contact lenses

Country Status (8)

Country Link
US (1) US11002884B2 (en)
EP (1) EP3186070B1 (en)
KR (1) KR102366047B1 (en)
CN (1) CN106715101B (en)
HU (1) HUE046948T2 (en)
MY (1) MY183678A (en)
SG (2) SG10201901379TA (en)
WO (1) WO2016032926A1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110167507A (en) * 2016-12-02 2019-08-23 佛罗里达大学研究基金会股份有限公司 Preservative is removed from eye drops
RU2766412C2 (en) * 2017-06-07 2022-03-15 Алькон Инк. Silicone hydrogel contact lenses
TWI640557B (en) * 2017-07-05 2018-11-11 晶碩光學股份有限公司 Contact lens with surface modification and the method for its preparation
WO2019150260A1 (en) * 2018-01-30 2019-08-08 Novartis Ag Contact lenses with a lubricious coating thereon
CN114158254B (en) * 2019-08-27 2022-11-18 东丽株式会社 Method for manufacturing medical device
US11754753B2 (en) * 2020-04-27 2023-09-12 Coopervision International Limited Antioxidant contact lens
JPWO2022224790A1 (en) * 2021-04-21 2022-10-27
KR102528506B1 (en) 2021-05-25 2023-05-09 한국과학기술연구원 Rehabilitation status monitoring system using analysis of exercise condition and electroencephalogram
KR102545476B1 (en) * 2021-12-09 2023-06-21 문샷옵티컬주식회사 Production method of silicone hydrogel lens improved functionally using MPC

Family Cites Families (486)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2296891A (en) 1940-11-09 1942-09-29 Celanese Corp Cement
US2926154A (en) 1957-09-05 1960-02-23 Hercules Powder Co Ltd Cationic thermosetting polyamide-epichlorohydrin resins and process of making same
US3224986A (en) 1962-04-18 1965-12-21 Hercules Powder Co Ltd Cationic epichlorohydrin modified polyamide reacted with water-soluble polymers
US3171752A (en) * 1962-07-11 1965-03-02 Burton Parsons Chemicals Inc Contact lens treating solution
NL128305C (en) 1963-09-11
SE306597B (en) 1964-12-17 1968-12-02 Incentive Ab
US3434984A (en) 1966-04-25 1969-03-25 Owens Illinois Inc Thermosetting cationic resin and method of making same
US3488327A (en) 1967-06-30 1970-01-06 Roehm & Haas Gmbh Preparation of coating materials
DE1745348A1 (en) 1967-12-01 1971-09-09 Roehm Gmbh Copolymers containing azlactone groups
US3598790A (en) 1966-07-01 1971-08-10 Roehm & Haas Gmbh Azlactone copolymers
US3617344A (en) 1966-08-05 1971-11-02 Us Health Education & Welfare Nonthrombogenic plastic surfaces and preparation thereof
GB1218394A (en) 1967-03-08 1971-01-06 Toho Kagaku Kogyo Kabushiki Ka Process for producing water-soluble thermosetting polymer
US3566874A (en) 1968-08-13 1971-03-02 Nat Patent Dev Corp Catheter
US3639141A (en) 1968-09-16 1972-02-01 Cordis Corp Heparinization of plastic
JPS4813341B1 (en) 1969-06-13 1973-04-26
US3663288A (en) 1969-09-04 1972-05-16 American Cyanamid Co Physiologically acceptible elastomeric article
US3772076A (en) 1970-01-26 1973-11-13 Hercules Inc Reaction products of epihalohydrin and polymers of diallylamine and their use in paper
US3616935A (en) 1970-02-05 1971-11-02 Dow Chemical Co Preparation of antithrombogenic surfaces
US3925178A (en) 1970-04-17 1975-12-09 Hymie D Gesser Contact lenses
US3700623A (en) 1970-04-22 1972-10-24 Hercules Inc Reaction products of epihalohydrin and polymers of diallylamine and their use in paper
US3695921A (en) 1970-09-09 1972-10-03 Nat Patent Dev Corp Method of coating a catheter
US3844989A (en) 1971-12-23 1974-10-29 Toray Industries Shampooer with rotary foam generating means anti-thrombogenic polymer compositions with internally bound heparin
US3892696A (en) 1972-05-12 1975-07-01 Grace W R & Co Polyureas and preparation thereof
US3975350A (en) 1972-08-02 1976-08-17 Princeton Polymer Laboratories, Incorporated Hydrophilic or hydrogel carrier systems such as coatings, body implants and other articles
US3813695A (en) 1973-02-21 1974-06-04 D Podell Surgical glove
US3900672A (en) 1973-04-04 1975-08-19 Hoya Lens Co Ltd Process for coating an optical material and the resulting product
US3861396A (en) 1973-08-08 1975-01-21 Hydro Med Sciences Inc Drainage tube
SE400173B (en) 1975-03-20 1978-03-20 Aminkemi Ab PROCEDURE FOR STABILIZING A HEPARINIZED SURFACE CONTAINING FOR BLOOD CONTACT RELEASE HEPARIN
FR2306243A1 (en) 1975-04-03 1976-10-29 Asahi Dow Ltd HYDROPHYL COATING COMPOSITION
DE2614662A1 (en) 1975-04-07 1977-01-27 Dow Chemical Co COMPOSITION FOR THE PRODUCTION OF ARTICLES SWELLABLE IN WATER
US4154898A (en) 1976-09-27 1979-05-15 The Dow Chemical Company Absorbent articles and methods for their preparation
US4143949A (en) 1976-10-28 1979-03-13 Bausch & Lomb Incorporated Process for putting a hydrophilic coating on a hydrophobic contact lens
US4182822A (en) 1976-11-08 1980-01-08 Chang Sing Hsiung Hydrophilic, soft and oxygen permeable copolymer composition
US4343927A (en) 1976-11-08 1982-08-10 Chang Sing Hsiung Hydrophilic, soft and oxygen permeable copolymer compositions
JPS5413694A (en) 1977-07-01 1979-02-01 Sumitomo Electric Industries Composite blood vessel prosthesis and method of producing same
US4136250A (en) 1977-07-20 1979-01-23 Ciba-Geigy Corporation Polysiloxane hydrogels
US4189546A (en) 1977-07-25 1980-02-19 Bausch & Lomb Incorporated Polysiloxane shaped article for use in biomedical applications
US4153641A (en) 1977-07-25 1979-05-08 Bausch & Lomb Incorporated Polysiloxane composition and contact lens
FR2402525A1 (en) 1977-09-12 1979-04-06 Toray Industries PROCESS FOR MANUFACTURING COMPOSITIONS OF SOFT CONTACT LENSES AND NEW PRODUCTS THUS OBTAINED
US4168112A (en) 1978-01-05 1979-09-18 Polymer Technology Corporation Contact lens with a hydrophilic, polyelectrolyte complex coating and method for forming same
US4298715A (en) 1978-03-01 1981-11-03 Monsanto Company Polyamine/epihalohydrin reaction products
US4217038A (en) 1978-06-05 1980-08-12 Bausch & Lomb Incorporated Glass coated polysiloxane contact lens
US4191596A (en) 1978-09-06 1980-03-04 Union Carbide Corporation Method and compositions for coating aluminum
US4280970A (en) 1979-01-19 1981-07-28 Puropore Inc. Polyoxyethylene grafted membrane materials with grafting links derived from a diisocyanate
US4261875A (en) 1979-01-31 1981-04-14 American Optical Corporation Contact lenses containing hydrophilic silicone polymers
US4298639A (en) 1979-03-19 1981-11-03 Monsanto Company Wet strength polymers
US4263188A (en) 1979-05-23 1981-04-21 Verbatim Corporation Aqueous coating composition and method
US4254248A (en) 1979-09-13 1981-03-03 Bausch & Lomb Incorporated Contact lens made from polymers of polysiloxane and polycyclic esters of acrylic acid or methacrylic acid
US4276402A (en) 1979-09-13 1981-06-30 Bausch & Lomb Incorporated Polysiloxane/acrylic acid/polcyclic esters of methacrylic acid polymer contact lens
US4312575A (en) 1979-09-18 1982-01-26 Peyman Gholam A Soft corneal contact lens with tightly cross-linked polymer coating and method of making same
US4260725A (en) 1979-12-10 1981-04-07 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes which are thermally bonded to polymerizable groups and which contain hydrophilic sidechains
US4259467A (en) 1979-12-10 1981-03-31 Bausch & Lomb Incorporated Hydrophilic contact lens made from polysiloxanes containing hydrophilic sidechains
US4293642A (en) 1980-05-13 1981-10-06 Gaf Corporation In photographic emulsion adhesion to a polyester film base
JPS5774369A (en) 1980-10-28 1982-05-10 Mitsui Petrochem Ind Ltd Coating composition
US4462665A (en) 1981-01-29 1984-07-31 The Kendall Company Composite hydrogel-forming lens and method of making same
US4355147A (en) 1981-02-26 1982-10-19 Bausch & Lomb Incorporated Polysiloxane with polycyclic modifier composition and biomedical devices
US4341889A (en) 1981-02-26 1982-07-27 Bausch & Lomb Incorporated Polysiloxane composition and biomedical devices
US4327203A (en) 1981-02-26 1982-04-27 Bausch & Lomb Incorporated Polysiloxane with cycloalkyl modifier composition and biomedical devices
US4495313A (en) 1981-04-30 1985-01-22 Mia Lens Production A/S Preparation of hydrogel for soft contact lens with water displaceable boric acid ester
US4373009A (en) 1981-05-18 1983-02-08 International Silicone Corporation Method of forming a hydrophilic coating on a substrate
US4379893A (en) 1981-08-26 1983-04-12 Diamond Shamrock Corporation Surface-treated soft contact lenses
DE3135830A1 (en) 1981-09-10 1983-03-24 Basf Ag, 6700 Ludwigshafen METHOD FOR THE PRODUCTION OF WATER-SOLUBLE, NITROGEN-CONDENSING PRODUCTS AND THE USE THEREOF IN PAPER PRODUCTION
US4444711A (en) 1981-12-21 1984-04-24 Husky Injection Molding Systems Ltd. Method of operating a two-shot injection-molding machine
US4661575A (en) 1982-01-25 1987-04-28 Hercules Incorporated Dicyclopentadiene polymer product
SE456347B (en) 1982-02-09 1988-09-26 Ird Biomaterial Ab SURFACE MODIFIED SOLID SUBSTRATE AND PROCEDURES FOR PRODUCING THEREOF
SE8200751L (en) 1982-02-09 1983-08-10 Olle Larm PROCEDURE FOR COVALENT COUPLING FOR MANUFACTURE OF CONJUGATE AND REQUIRED PRODUCTS
US4487808A (en) 1982-04-22 1984-12-11 Astra Meditec Aktiebolag Medical article having a hydrophilic coating
US4499154A (en) 1982-09-03 1985-02-12 Howard L. Podell Dipped rubber article
US4460534A (en) 1982-09-07 1984-07-17 International Business Machines Corporation Two-shot injection molding
US5002582A (en) 1982-09-29 1991-03-26 Bio-Metric Systems, Inc. Preparation of polymeric surfaces via covalently attaching polymers
US4973493A (en) 1982-09-29 1990-11-27 Bio-Metric Systems, Inc. Method of improving the biocompatibility of solid surfaces
US5217492A (en) 1982-09-29 1993-06-08 Bio-Metric Systems, Inc. Biomolecule attachment to hydrophobic surfaces
US4486577A (en) 1982-10-12 1984-12-04 Ciba-Geigy Corporation Strong, silicone containing polymers with high oxygen permeability
US4543398A (en) 1983-04-28 1985-09-24 Minnesota Mining And Manufacturing Company Ophthalmic devices fabricated from urethane acrylates of polysiloxane alcohols
US4527293A (en) 1983-05-18 1985-07-09 University Of Miami Hydrogel surface of urological prosthesis
US4521564A (en) 1984-02-10 1985-06-04 Warner-Lambert Company Covalent bonded antithrombogenic polyurethane material
US4695608A (en) 1984-03-29 1987-09-22 Minnesota Mining And Manufacturing Company Continuous process for making polymers having pendant azlactone or macromolecular moieties
AU566085B2 (en) 1984-06-04 1987-10-08 Terumo Kabushiki Kaisha Medical instrument with surface treatment
US4959074A (en) 1984-08-23 1990-09-25 Gergory Halpern Method of hydrophilic coating of plastics
US4605712A (en) 1984-09-24 1986-08-12 Ciba-Geigy Corporation Unsaturated polysiloxanes and polymers thereof
AT380897B (en) 1984-12-10 1986-07-25 Koller Anton MIXTURE FOR THE CARE AND CLEANING OF CONTACT LENSES
US4833218A (en) 1984-12-18 1989-05-23 Dow Corning Corporation Hydrophilic silicone-organic copolymer elastomers containing bioactine agent
US4546123A (en) 1984-12-28 1985-10-08 Alcon Laboratories, Inc. Polymer hydrogels adapted for use as soft contact lenses, and method of preparing same
JPH0674369B2 (en) 1985-03-14 1994-09-21 大日本インキ化学工業株式会社 Method for producing aqueous dispersion of vinyl copolymer resin
DE3517615A1 (en) 1985-05-15 1986-11-20 Titmus Eurocon Kontaktlinsen GmbH, 8750 Aschaffenburg HYDROPHILIC SILICONE RUBBER BODY AND METHOD FOR THE PRODUCTION THEREOF
US4684538A (en) 1986-02-21 1987-08-04 Loctite Corporation Polysiloxane urethane compounds and adhesive compositions, and method of making and using the same
US4720512A (en) 1986-03-24 1988-01-19 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity
US4786556A (en) 1986-03-24 1988-11-22 Becton, Dickinson And Company Polymeric articles having enhanced antithrombogenic activity
DE3708308A1 (en) 1986-04-10 1987-10-22 Bayer Ag CONTACT OPTICAL ITEMS
US4791175A (en) 1986-08-04 1988-12-13 Ciba-Geigy Corporation Particulate hydroperoxidized poly-n-vinyl lactam, its preparation and use thereof
DE3778446D1 (en) 1986-08-18 1992-05-27 Mueller Lierheim Wolfgang G K CONTACT LENS.
US5263992A (en) 1986-10-17 1993-11-23 Bio-Metric Systems, Inc. Biocompatible device with covalently bonded biocompatible agent
US4979959A (en) 1986-10-17 1990-12-25 Bio-Metric Systems, Inc. Biocompatible coating for solid surfaces
US4734475A (en) 1986-12-15 1988-03-29 Ciba-Geigy Corporation Wettable surface modified contact lens fabricated from an oxirane containing hydrophobic polymer
US5712327A (en) 1987-01-07 1998-01-27 Chang; Sing-Hsiung Soft gas permeable contact lens having improved clinical performance
US5108776A (en) 1987-04-10 1992-04-28 University Of Florida Ocular implants and methods for their manufacture
US5290548A (en) 1987-04-10 1994-03-01 University Of Florida Surface modified ocular implants, surgical instruments, devices, prostheses, contact lenses and the like
US4837289A (en) 1987-04-30 1989-06-06 Ciba-Geigy Corporation UV- and heat curable terminal polyvinyl functional macromers and polymers thereof
JP2551580B2 (en) 1987-04-30 1996-11-06 ホ−ヤ株式会社 How to make contact lenses hydrophilic
US5059659A (en) 1987-05-29 1991-10-22 Harry P. Gregor Surface treatments to impart hydrophilicity
US4978713A (en) 1987-12-16 1990-12-18 Ciba-Geigy Corporation Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom
US4943460A (en) 1988-02-19 1990-07-24 Snyder Laboratories, Inc. Process for coating polymer surfaces and coated products produced using such process
US5070170A (en) 1988-02-26 1991-12-03 Ciba-Geigy Corporation Wettable, rigid gas permeable, substantially non-swellable contact lens containing block copolymer polysiloxane-polyoxyalkylene backbone units, and use thereof
AU629203B2 (en) 1988-03-23 1992-10-01 E.I. Du Pont De Nemours And Company Low coefficient of friction surface
JP2561309B2 (en) 1988-03-28 1996-12-04 テルモ株式会社 Medical material and manufacturing method thereof
US5061738A (en) 1988-04-18 1991-10-29 Becton, Dickinson And Company Blood compatible, lubricious article and composition and method therefor
US4954587A (en) 1988-07-05 1990-09-04 Ciba-Geigy Corporation Dimethylacrylamide-copolymer hydrogels with high oxygen permeability
US5019393A (en) 1988-08-03 1991-05-28 New England Deaconess Hospital Corporation Biocompatible substance with thromboresistance
KR900701332A (en) 1988-08-09 1990-12-01 마에다 카쓰노스케 Active Medical Materials and Manufacturing Method Thereof
JPH0651795B2 (en) 1988-09-16 1994-07-06 信越化学工業株式会社 Methacryl functional dimethyl polysiloxane
US5053048A (en) 1988-09-22 1991-10-01 Cordis Corporation Thromboresistant coating
US5270046A (en) 1988-09-27 1993-12-14 Ube Industries, Ltd. Heparin bound anti-thrombotic material
US4983702A (en) 1988-09-28 1991-01-08 Ciba-Geigy Corporation Crosslinked siloxane-urethane polymer contact lens
EP0362137A3 (en) 1988-09-28 1991-09-04 Ciba-Geigy Ag Molded polymers with hydrophilic surfaces, and process for making them
US5510418A (en) 1988-11-21 1996-04-23 Collagen Corporation Glycosaminoglycan-synthetic polymer conjugates
US5039459A (en) 1988-11-25 1991-08-13 Johnson & Johnson Vision Products, Inc. Method of forming shaped hydrogel articles including contact lenses
US5214452A (en) 1988-12-19 1993-05-25 Ciba-Geigy Corporation Hydrogels based on fluorine-containing and saccharide monomers
EP0374752B1 (en) 1988-12-19 1995-01-25 Ciba-Geigy Ag Hydrogels based on monomers containing fluor and saccharide
US4973359A (en) 1989-01-04 1990-11-27 Nippon Paint Co., Ltd. Surface treatment chemical and bath for forming hydrophilic coatings and method of surface-treating aluminum members
US4968532A (en) 1989-01-13 1990-11-06 Ciba-Geigy Corporation Process for graft copolymerization on surfaces of preformed substrates to modify surface properties
US4978481A (en) 1989-01-13 1990-12-18 Ciba-Geigy Corporation Process for the encapsulation of preformed substrates by graft copolymerization
US4954586A (en) 1989-01-17 1990-09-04 Menicon Co., Ltd Soft ocular lens material
US5091205A (en) 1989-01-17 1992-02-25 Union Carbide Chemicals & Plastics Technology Corporation Hydrophilic lubricious coatings
US5262484A (en) 1989-04-10 1993-11-16 Minnesota Mining And Manufacturing Company Azlactone graft copolymers
SG43306A1 (en) 1989-04-14 1997-10-17 Jessen Wesley Corp Color-binding mechanism for contact lenses
US5080924A (en) 1989-04-24 1992-01-14 Drexel University Method of making biocompatible, surface modified materials
US4990357A (en) 1989-05-04 1991-02-05 Becton, Dickinson And Company Elastomeric segmented hydrophilic polyetherurethane based lubricious coatings
US5034461A (en) 1989-06-07 1991-07-23 Bausch & Lomb Incorporated Novel prepolymers useful in biomedical devices
US5272012A (en) 1989-06-23 1993-12-21 C. R. Bard, Inc. Medical apparatus having protective, lubricious coating
JPH04501882A (en) 1989-09-14 1992-04-02 チヤン，シン―シウン Flexible gas permeable contact lenses with improved clinical performance
US5049403A (en) 1989-10-12 1991-09-17 Horsk Hydro A.S. Process for the preparation of surface modified solid substrates
US5079319A (en) 1989-10-25 1992-01-07 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5010141A (en) 1989-10-25 1991-04-23 Ciba-Geigy Corporation Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof
US5135516A (en) 1989-12-15 1992-08-04 Boston Scientific Corporation Lubricious antithrombogenic catheters, guidewires and coatings
GB9009097D0 (en) 1990-04-23 1990-06-20 Lrc Products Method of making dipped rubber articles
DE4026978A1 (en) 1990-08-25 1992-02-27 Bayer Ag Coated substrates for electro=optical applications, etc.
JPH0783761B2 (en) 1990-10-04 1995-09-13 テルモ株式会社 Medical equipment
US5160790A (en) 1990-11-01 1992-11-03 C. R. Bard, Inc. Lubricious hydrogel coatings
US5132108A (en) 1990-11-08 1992-07-21 Cordis Corporation Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents
DE69121581T2 (en) 1990-11-27 1997-03-20 Bausch & Lomb SURFACE-ACTIVE MACROMONOMERS
US5135297A (en) 1990-11-27 1992-08-04 Bausch & Lomb Incorporated Surface coating of polymer objects
US5407715A (en) 1990-11-28 1995-04-18 Tactyl Technologies, Inc. Elastomeric triblock copolymer compositions and articles made therewith
US5112900A (en) 1990-11-28 1992-05-12 Tactyl Technologies, Inc. Elastomeric triblock copolymer compositions and articles made therewith
AU649287B2 (en) 1990-12-19 1994-05-19 Novartis Ag Process for rendering contact lenses hydrophilic
US5270415A (en) 1990-12-21 1993-12-14 Allergan Inc. Balanced charge polymer and hydrophilic contact lens manufactured therefrom
US5739236A (en) 1991-04-24 1998-04-14 Biocompatibles Limited Biocompatible zwitterion polymers
US5397848A (en) 1991-04-25 1995-03-14 Allergan, Inc. Enhancing the hydrophilicity of silicone polymers
US5443907A (en) 1991-06-18 1995-08-22 Scimed Life Systems, Inc. Coating for medical insertion guides
GB9113875D0 (en) 1991-06-27 1991-08-14 Biointeractions Ltd Polymer coatings
US6743878B2 (en) 1991-07-05 2004-06-01 Biocompatibles Uk Limited Polymeric surface coatings
US5705583A (en) 1991-07-05 1998-01-06 Biocompatibles Limited Polymeric surface coatings
US6225431B1 (en) 1991-07-05 2001-05-01 Biocompatibles Limited Biocompatibilizing process
DE69230823T2 (en) 1991-07-05 2000-07-27 Biocompatibles Ltd POLYMER SURFACE COATING COMPOSITIONS
US6090901A (en) 1991-07-05 2000-07-18 Biocompatibles Limited Polymeric surface coatings
US6284854B1 (en) 1991-07-05 2001-09-04 Biccompatibles Limited Polymeric surface coatings
US5210111A (en) 1991-08-22 1993-05-11 Ciba-Geigy Corporation Crosslinked hydrogels derived from hydrophilic polymer backbones
DE69216100T2 (en) 1991-09-12 1997-06-12 Bausch & Lomb WETABLE SILICONE-HYDROGEL COMPOSITIONS AND METHOD FOR THE PRODUCTION THEREOF
WO1993005825A1 (en) 1991-09-20 1993-04-01 Baxter International Inc. Processes for reducing the thrombogenicity of biomaterials
SG54134A1 (en) 1991-10-14 1998-11-16 Nof Corp Treating solution for contact lenses
JP3093375B2 (en) 1991-11-01 2000-10-03 株式会社東海メディカルプロダクツ Immobilization method of antithrombotic substance
US5352714A (en) 1991-11-05 1994-10-04 Bausch & Lomb Incorporated Wettable silicone hydrogel compositions and methods for their manufacture
CA2122251C (en) 1991-11-05 1998-02-03 Yu-Chin Lai Wettable silicone hydrogel compositions and methods for their manufacture
GB9124353D0 (en) 1991-11-15 1992-01-08 Albright & Wilson Immobilisation of metal contaminants from a liquid to a solid metal
JPH06506019A (en) 1991-12-18 1994-07-07 シメッド　ライフ　システムズ　インコーポレイテッド Lubricious polymer network
US6314199B1 (en) 1991-12-18 2001-11-06 Novartis Ag Process and apparatus for examining optical components, especially optical components for the eye and device for illuminating clear-transparent
IL100443A (en) 1991-12-20 1995-03-30 Dotan Gideon Inspection system for detecting surface flaws
EP0585436B1 (en) 1992-02-13 2000-05-03 SurModics, Inc. Immobilization of chemical species in crosslinked matrices
US5470944A (en) 1992-02-13 1995-11-28 Arch Development Corporation Production of high molecular weight polylactic acid
JPH05285164A (en) 1992-04-03 1993-11-02 Unitika Ltd Antithrombotic intraocular lens
US5358995A (en) 1992-05-15 1994-10-25 Bausch & Lomb Incorporated Surface wettable silicone hydrogels
JPH0649251A (en) 1992-06-09 1994-02-22 Ciba Geigy Ag Method of grafting onto surface of premolded substrate to modify surface property
US5805264A (en) 1992-06-09 1998-09-08 Ciba Vision Corporation Process for graft polymerization on surfaces of preformed substates to modify surface properties
DK172393B1 (en) 1992-06-10 1998-05-18 Maersk Medical As Process for producing an article having friction-reducing surface coating, coating material for use in the manufacture of such article, and using an osmolality-increasing compound in slurry or emulsified form in the coating material
US5292514A (en) 1992-06-24 1994-03-08 Minnesota Mining And Manufacturing Company Azlactone-functional substrates, corneal prostheses, and manufacture and use thereof
JP3195662B2 (en) 1992-08-24 2001-08-06 株式会社メニコン Ophthalmic lens materials
JP2774233B2 (en) 1992-08-26 1998-07-09 株式会社メニコン Ophthalmic lens materials
US5310571A (en) 1992-09-01 1994-05-10 Allergan, Inc. Chemical treatment to improve oxygen permeability through and protein deposition on hydrophilic (soft) and rigid gas permeable (RGP) contact lenses
IL106922A (en) 1992-09-14 1998-08-16 Novartis Ag Composite materials with one or more wettable surfaces and process for their preparation
KR0122741B1 (en) 1992-09-23 1997-11-17 배순훈 Memory having parallel architecture
US5409731A (en) 1992-10-08 1995-04-25 Tomei Sangyo Kabushiki Kaisha Method for imparting a hydrophilic nature to a contact lens
WO1994012570A1 (en) 1992-11-30 1994-06-09 Bulk Chemicals, Inc. A method and composition for treating metal surfaces
IL107602A0 (en) 1992-12-21 1994-02-27 Johnson & Johnson Vision Prod Method of inspecting ophthalmic lenses
IL107601A (en) 1992-12-21 1997-09-30 Johnson & Johnson Vision Prod Illumination and imaging subsystems for a lens inspection system
NZ250042A (en) 1992-12-21 1997-01-29 Johnson & Johnson Vision Prod Robotic inspection of ophthalmic lenses
IL107603A (en) 1992-12-21 1997-01-10 Johnson & Johnson Vision Prod Ophthalmic lens inspection method and apparatus
IL107605A (en) 1992-12-21 1998-01-04 Johnson & Johnson Vision Prod Lens inspection system
GB9226791D0 (en) 1992-12-23 1993-02-17 Biocompatibles Ltd New materials
US5308641A (en) 1993-01-19 1994-05-03 Medtronic, Inc. Biocompatibility of solid surfaces
US5350800A (en) 1993-01-19 1994-09-27 Medtronic, Inc. Method for improving the biocompatibility of solid surfaces
WO1994016803A1 (en) 1993-01-29 1994-08-04 Minnesota Mining And Manufacturing Company Thermally induced phase separated azlactone membrane
CA2114697C (en) 1993-02-08 2006-06-13 Kenichi Shimura Medical tool having lubricious surface in a wetted state and method for production thereof
JPH08507715A (en) 1993-03-18 1996-08-20 シーダーズ サイナイ メディカル センター Drug-inducing and releasable polymeric coatings for bioartificial components
US5531715A (en) 1993-05-12 1996-07-02 Target Therapeutics, Inc. Lubricious catheters
TW328535B (en) 1993-07-02 1998-03-21 Novartis Ag Functional photoinitiators and their manufacture
US6800225B1 (en) 1994-07-14 2004-10-05 Novartis Ag Process and device for the manufacture of mouldings and mouldings manufactured in accordance with that process
US5578675A (en) 1993-07-21 1996-11-26 Basf Corporation Non-isocyanate basecoat/clearcoat coating compositions which may be ambient cured
TW325744U (en) 1993-07-21 1998-01-21 Ciba Geigy Ag Two-sided contact lens mold
EP0882970B1 (en) 1993-07-29 2001-09-19 Wesley Jessen Corporation Inspection system for optical components
TW272976B (en) 1993-08-06 1996-03-21 Ciba Geigy Ag
TW253849B (en) 1993-08-09 1995-08-11 Ciba Geigy
US5408002A (en) 1993-09-09 1995-04-18 Minnesota Mining And Manufacturing Company Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both
US5514478A (en) 1993-09-29 1996-05-07 Alcan International Limited Nonabrasive, corrosion resistant, hydrophilic coatings for aluminum surfaces, methods of application, and articles coated therewith
US5723145A (en) 1993-09-30 1998-03-03 Takiron Co., Ltd. Transdermal absorption preparation
US5936703A (en) 1993-10-13 1999-08-10 Nof Corporation Alkoxysilane compound, surface processing solution and contact lens
GB9321714D0 (en) 1993-10-21 1993-12-15 Sandoz Ltd Improvements in or relating to organic compounds
EP0655470B1 (en) 1993-11-26 1999-05-12 Novartis AG Cross-linkable copolymers and hydrogels
US5712356A (en) 1993-11-26 1998-01-27 Ciba Vision Corporation Cross-linkable copolymers and hydrogels
US5894002A (en) 1993-12-13 1999-04-13 Ciba Vision Corporation Process and apparatus for the manufacture of a contact lens
JP3734512B2 (en) 1993-12-27 2006-01-11 株式会社メニコン Contact lens appearance inspection method and appearance inspection apparatus
JPH10500712A (en) 1994-04-11 1998-01-20 ヘキスト セラニーズ コーポレーション Superabsorbent polymer and products obtained therefrom
US5476665A (en) 1994-04-13 1995-12-19 Minnesota Mining And Manufacturing Company Azlactone functional particles incorporated in a membrane formed by solvent phase inversion
US5626000A (en) 1994-06-10 1997-05-06 Johnson & Johnson Vision Products, Inc. Packaging arrangement
US5500732A (en) 1994-06-10 1996-03-19 Johnson & Johnson Vision Products, Inc. Lens inspection system and method
US5843346A (en) 1994-06-30 1998-12-01 Polymer Technology Corporation Method of cast molding contact lenses
US5670558A (en) 1994-07-07 1997-09-23 Terumo Kabushiki Kaisha Medical instruments that exhibit surface lubricity when wetted
US7468398B2 (en) 1994-09-06 2008-12-23 Ciba Vision Corporation Extended wear ophthalmic lens
US5760100B1 (en) 1994-09-06 2000-11-14 Ciba Vision Corp Extended wear ophthalmic lens
US5509899A (en) 1994-09-22 1996-04-23 Boston Scientific Corp. Medical device with lubricious coating
IT1270125B (en) 1994-10-05 1997-04-28 Spherilene Srl PROCESS FOR THE (CO) POLYMERIZATION OF OLEFINE
US5681510A (en) 1994-10-13 1997-10-28 Bausch & Lomb Incorporated Method for treating plastic mold pieces
US6342570B1 (en) 1994-11-14 2002-01-29 Novartis Ag Cross-linkable copolymers and hydrogels
JP3647093B2 (en) 1994-11-17 2005-05-11 株式会社メニコン Hydrophilized oxygen permeable contact lens and method for producing the same
EP0712867B1 (en) 1994-11-18 1999-07-14 Novartis AG Polymer networks of water-soluble prepolymers
US5665840A (en) 1994-11-18 1997-09-09 Novartis Corporation Polymeric networks from water-soluble prepolymers
US5510004A (en) 1994-12-01 1996-04-23 Hercules Incorporated Azetidinium polymers for improving wet strength of paper
SE503711C2 (en) 1994-12-14 1996-08-12 Medicarb Ab Multistage procedure for coating an intraocular lens
US5700559A (en) 1994-12-16 1997-12-23 Advanced Surface Technology Durable hydrophilic surface coatings
TW353086B (en) 1994-12-30 1999-02-21 Novartis Ag Method for multistep coating of a surface
US5995213A (en) 1995-01-17 1999-11-30 Johnson & Johnson Vision Products, Inc. Lens inspection system
US5532311A (en) 1995-02-01 1996-07-02 Minnesota Mining And Manufacturing Company Process for modifying surfaces
TW349967B (en) 1995-02-03 1999-01-11 Novartis Ag Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor
ATE178414T1 (en) 1995-02-03 1999-04-15 Novartis Ag CROSS-LINKED POLYMERS CONTAINING ESTER OR AMIDE GROUPS
US5599576A (en) 1995-02-06 1997-02-04 Surface Solutions Laboratories, Inc. Medical apparatus with scratch-resistant coating and method of making same
HU219815B (en) 1995-02-07 2001-08-28 Fidia Advanced Biopolymers S.R.L. Process for the coating of objects with hyaluronic acid, derivatives thereof, and semisynthetic polymers
US5869127A (en) 1995-02-22 1999-02-09 Boston Scientific Corporation Method of providing a substrate with a bio-active/biocompatible coating
US6179817B1 (en) 1995-02-22 2001-01-30 Boston Scientific Corporation Hybrid coating for medical devices
US5702754A (en) 1995-02-22 1997-12-30 Meadox Medicals, Inc. Method of providing a substrate with a hydrophilic coating and substrates, particularly medical devices, provided with such coatings
JPH08239639A (en) 1995-03-02 1996-09-17 Sekisui Chem Co Ltd Pressure-sensitive adhesive composition and article coated therewith
US5633504A (en) 1995-03-30 1997-05-27 Wesley-Jessen Corporation Inspection of optical components
US5674942A (en) 1995-03-31 1997-10-07 Johnson & Johnson Vision Products, Inc. Interpenetrating polymer networks for contact lens production
TW393498B (en) 1995-04-04 2000-06-11 Novartis Ag The preparation and use of Polysiloxane-comprising perfluoroalkyl ethers
TW585882B (en) 1995-04-04 2004-05-01 Novartis Ag A method of using a contact lens as an extended wear lens and a method of screening an ophthalmic lens for utility as an extended-wear lens
SI0819258T1 (en) 1995-04-04 2002-04-30 Novartis Ag Extended wear ophthalmic lens
US5688855A (en) 1995-05-01 1997-11-18 S.K.Y. Polymers, Inc. Thin film hydrophilic coatings
AU5630796A (en) 1995-05-25 1996-12-11 Minnesota Mining And Manufacturing Company Process for producing biocompatible surfaces
US5583463A (en) 1995-05-30 1996-12-10 Micron Technology, Inc. Redundant row fuse bank circuit
US5731087A (en) 1995-06-07 1998-03-24 Union Carbide Chemicals & Plastics Technology Corporation Lubricious coatings containing polymers with vinyl and carboxylic acid moieties
US6087462A (en) 1995-06-07 2000-07-11 Biocompatibles Limited Polymeric surface coatings
US5620738A (en) 1995-06-07 1997-04-15 Union Carbide Chemicals & Plastics Technology Corporation Non-reactive lubicious coating process
AUPN354595A0 (en) 1995-06-14 1995-07-06 Ciba-Geigy Ag Novel materials
TW428018B (en) 1995-06-29 2001-04-01 Ciba Sc Holding Ag Aminosilane salts and silanamides of carboxylic acids as corrosion inhibitors
US5922161A (en) 1995-06-30 1999-07-13 Commonwealth Scientific And Industrial Research Organisation Surface treatment of polymers
US5874127A (en) 1995-08-16 1999-02-23 Ciba Vision Corporation Method and apparatus for gaseous treatment
US5672638A (en) 1995-08-22 1997-09-30 Medtronic, Inc. Biocompatability for solid surfaces
DE69617637T2 (en) 1995-09-06 2002-07-18 Menicon Co Ltd METHOD FOR THE PRODUCTION OF CONTACT LENSES AND THE CONTACT LENSES PRODUCED IN THIS PROCESS
EP0763754B1 (en) 1995-09-13 2003-01-08 Seikagaku Kogyo Kabushiki Kaisha (Seikagaku Corporation) Photocured crosslinked-hyaluronic acid contact lens
AU698522B2 (en) 1995-09-29 1998-10-29 Johnson & Johnson Vision Products, Inc. Lens parameter measurement using optical sectioning
US6007526A (en) 1995-10-12 1999-12-28 Hollister Incorporated Male external catheter with short annular sealing flap
US5804318A (en) 1995-10-26 1998-09-08 Corvita Corporation Lubricious hydrogel surface modification
US6509098B1 (en) 1995-11-17 2003-01-21 Massachusetts Institute Of Technology Poly(ethylene oxide) coated surfaces
JP2001518061A (en) 1995-12-07 2001-10-09 ボシュ アンド ロム インコーポレイテッド Monomer units useful for reducing the modulus of silicone hydrogels
US5922249A (en) 1995-12-08 1999-07-13 Novartis Ag Ophthalmic lens production process
ATE336307T1 (en) 1995-12-08 2006-09-15 Novartis Pharma Gmbh PLASMA-INDUCED POLYMER COATINGS
EP0876165B1 (en) 1995-12-18 2006-06-21 Angiotech BioMaterials Corp. Crosslinked polymer compositions and methods for their use
EP0780419A1 (en) 1995-12-22 1997-06-25 Holland Biomaterials Group B.V. Multi-functional site containing polymers, and applications thereof
US6271332B1 (en) 1995-12-22 2001-08-07 Novartis Ag Polyurethanes made from polysiloxane/polyol macromers
CN1210554A (en) 1996-02-09 1999-03-10 表面溶解实验室公司 Water-based hydrophilic coating compositions and articles prepared therefrom
US5792531A (en) 1996-02-20 1998-08-11 Tactyl Technologies, Inc. Readily donned, powder free elastomeric article
US5779943A (en) 1996-03-19 1998-07-14 Johnson & Johnson Vision Products, Inc. Molded polymeric object with wettable surface made from latent-hydrophilic monomers
US6096138A (en) 1997-04-30 2000-08-01 Bausch & Lomb Incorporated Method for inhibiting the deposition of protein on contact lens
US5811151A (en) 1996-05-31 1998-09-22 Medtronic, Inc. Method of modifying the surface of a medical device
EP0814116A1 (en) 1996-06-19 1997-12-29 Hüls Aktiengesellschaft Hydrophilic coating of polymeric substrate surfaces
US5807944A (en) 1996-06-27 1998-09-15 Ciba Vision Corporation Amphiphilic, segmented copolymer of controlled morphology and ophthalmic devices including contact lenses made therefrom
US6174326B1 (en) 1996-09-25 2001-01-16 Terumo Kabushiki Kaisha Radiopaque, antithrombogenic stent and method for its production
US6169127B1 (en) 1996-08-30 2001-01-02 Novartis Ag Plasma-induced polymer coatings
US5800412A (en) 1996-10-10 1998-09-01 Sts Biopolymers, Inc. Hydrophilic coatings with hydrating agents
JP2001502734A (en) 1996-10-21 2001-02-27 ノバルティス アクチエンゲゼルシャフト Crosslinkable polymer
US6639007B2 (en) 1996-11-15 2003-10-28 Tactyl Technologies, Inc. Elastomeric copolymer compositions and articles made therewith
AR009439A1 (en) 1996-12-23 2000-04-12 Novartis Ag AN ARTICLE THAT INCLUDES A SUBSTRATE WITH A PRIMARY POLYMERIC COATING THAT CARRIES REACTIVE GROUPS PREDOMINANTLY ON ITS SURFACE, A METHOD FOR PREPARING SUCH AN ARTICLE, AN ARTICLE THAT HAS A HYBRID-TYPE COATING AND A CONTACT LENS
US6306514B1 (en) 1996-12-31 2001-10-23 Ansell Healthcare Products Inc. Slip-coated elastomeric flexible articles and their method of manufacture
US5882687A (en) 1997-01-10 1999-03-16 Allergan Compositions and methods for storing contact lenses
US6018001A (en) 1997-01-23 2000-01-25 Menicon Co., Ltd. Process for producing contact lens with hydrophilic surface and contact lens obtained thereby
US5997517A (en) 1997-01-27 1999-12-07 Sts Biopolymers, Inc. Bonding layers for medical device surface coatings
TW425403B (en) 1997-02-04 2001-03-11 Novartis Ag Branched polyurethane (meth)acrylate prepolymers, opthal-mic mouldings derived therefrom and processes for their manufacture
EP0867456A1 (en) 1997-02-04 1998-09-30 Novartis AG Ophthalmic moulded part
US5801822A (en) 1997-02-06 1998-09-01 Pbh, Inc. Ophthalmic lens inspection system
US5818573A (en) 1997-02-06 1998-10-06 Pbh, Inc. Opthalmic lens inspection system
DE69804946T2 (en) 1997-02-21 2002-10-02 Novartis Ag OPTHALMIC SHAPE
US5879697A (en) 1997-04-30 1999-03-09 Schneider Usa Inc Drug-releasing coatings for medical devices
US6221467B1 (en) 1997-06-03 2001-04-24 Scimed Life Systems, Inc. Coating gradient for lubricious coatings on balloon catheters
GB9711818D0 (en) 1997-06-06 1997-08-06 Bausch & Lomb Contact lens packing solutions and methods for improving the comfort of disposable contact lenses
US6866938B2 (en) 1997-07-22 2005-03-15 Nissha Printing Co., Ltd. Foil-detecting sheet and method of producing a foil-decorated resin article using the same
US6165322A (en) 1997-07-29 2000-12-26 Hercules Incorporated Polyamidoamine/epichlorohydrin resins bearing polyol sidechains as dry strength agents
EP1017734B1 (en) 1997-09-16 2002-08-28 Novartis AG Crosslinkable polyurea polymers
EP1023617A1 (en) 1997-09-23 2000-08-02 Novartis AG Method for hydrogel surface treatment and article formed therefrom
US5858653A (en) 1997-09-30 1999-01-12 Surmodics, Inc. Reagent and method for attaching target molecules to a surface
TW429327B (en) 1997-10-21 2001-04-11 Novartis Ag Single mould alignment
US6054504A (en) 1997-12-31 2000-04-25 Hydromer, Inc. Biostatic coatings for the reduction and prevention of bacterial adhesion
US6451871B1 (en) 1998-11-25 2002-09-17 Novartis Ag Methods of modifying surface characteristics
ES2200496T3 (en) 1998-01-09 2004-03-01 Novartis Ag POLYMER COATING.
JPH11223901A (en) 1998-02-06 1999-08-17 Fuji Photo Film Co Ltd Heat-developable recording material
US5962548A (en) 1998-03-02 1999-10-05 Johnson & Johnson Vision Products, Inc. Silicone hydrogel polymers
US6367929B1 (en) 1998-03-02 2002-04-09 Johnson & Johnson Vision Care, Inc. Hydrogel with internal wetting agent
US6822016B2 (en) 2001-09-10 2004-11-23 Johnson & Johnson Vision Care, Inc. Biomedical devices containing internal wetting agents
US5998498A (en) 1998-03-02 1999-12-07 Johnson & Johnson Vision Products, Inc. Soft contact lenses
US7052131B2 (en) 2001-09-10 2006-05-30 J&J Vision Care, Inc. Biomedical devices containing internal wetting agents
US6096726A (en) 1998-03-11 2000-08-01 Surface Solutions Laboratories Incorporated Multicomponent complex for use with substrate
EP0949290B1 (en) 1998-04-09 2006-12-27 Nippon Shokubai Co., Ltd. Crosslinked polymer particle and its production process and use
US6686054B2 (en) 1998-04-22 2004-02-03 Sri International Method and composition for the sizing of paper using azetidinium and/or guanidine polymers
TW473488B (en) 1998-04-30 2002-01-21 Novartis Ag Composite materials, biomedical articles formed thereof and process for their manufacture
US6348507B1 (en) 1998-05-05 2002-02-19 Bausch & Lomb Incorporated Surface treatment of silicone hydrogel contact lenses
WO1999057177A1 (en) 1998-05-05 1999-11-11 Bausch & Lomb Incorporated Plasma surface treatment of silicone hydrogel contact lenses
US6087415A (en) 1998-06-11 2000-07-11 Johnson & Johnson Vision Care, Inc. Biomedical devices with hydrophilic coatings
US6106889A (en) 1998-06-11 2000-08-22 Biocoat Incorporated Method of selective coating of articles
US6500481B1 (en) 1998-06-11 2002-12-31 Johnson & Johnson Vision Care, Inc. Biomedical devices with amid-containing coatings
US6039913A (en) 1998-08-27 2000-03-21 Novartis Ag Process for the manufacture of an ophthalmic molding
US6099852A (en) 1998-09-23 2000-08-08 Johnson & Johnson Vision Products, Inc. Wettable silicone-based lenses
US6149842A (en) 1998-11-12 2000-11-21 Novartis Ag Methods and compositions for manufacturing tinted ophthalmic lenses
US6207796B1 (en) 1998-11-18 2001-03-27 Nippon Shokubai Co., Ltd. Production process for hydrophilic polymer
EP1002807A1 (en) 1998-11-20 2000-05-24 Novartis AG Functionalized resin derived from polyallylamine
US5981675A (en) 1998-12-07 1999-11-09 Bausch & Lomb Incorporated Silicone-containing macromonomers and low water materials
TW480246B (en) 1998-12-18 2002-03-21 Kimberly Clark Co Cationically charged coating on glass fibers and method for making the same
US6537614B1 (en) 1998-12-18 2003-03-25 Kimberly-Clark Worldwide, Inc. Cationically charged coating on hydrophobic polymer fibers with poly (vinyl alcohol) assist
US6550915B1 (en) 1998-12-21 2003-04-22 Bausch & Lomb Incorporated Surface treatment of fluorinated contact lens materials
US6517678B1 (en) 2000-01-20 2003-02-11 Kimberly-Clark Worldwide, Inc. Modified polysaccharides containing amphiphillic hydrocarbon moieties
US6896769B2 (en) 1999-01-25 2005-05-24 Kimberly-Clark Worldwide, Inc. Modified condensation polymers containing azetidinium groups in conjunction with amphiphilic hydrocarbon moieties
US6340465B1 (en) 1999-04-12 2002-01-22 Edwards Lifesciences Corp. Lubricious coatings for medical devices
US6440571B1 (en) * 1999-05-20 2002-08-27 Bausch & Lomb Incorporated Surface treatment of silicone medical devices with reactive hydrophilic polymers
US6630243B2 (en) 1999-05-20 2003-10-07 Bausch & Lomb Incorporated Surface treatment of silicone hydrogel contact lenses comprising hydrophilic polymer chains attached to an intermediate carbon coating
ATE313607T1 (en) 1999-07-08 2006-01-15 Hercules Inc COMPOSITION FOR GIVING DESIRED PROPERTIES TO MATERIALS
US7344607B2 (en) 1999-07-08 2008-03-18 Ge Betz, Inc. Non-chromate conversion coating treatment for metals
BR0013052A (en) 1999-07-27 2002-04-09 Bausch & Lomb Method for preparing a silicone prepolymer hydrogel; hydrogel containing silicone; contact lens and intraocular lens
EP1214883B1 (en) 1999-09-20 2003-11-26 Menicon Co., Ltd. Liquid preparation for contact lenses
US6478423B1 (en) 1999-10-12 2002-11-12 Johnson & Johnson Vison Care, Inc. Contact lens coating selection and manufacturing process
JP2001163933A (en) 1999-10-27 2001-06-19 Novartis Ag Method for moldifying surface of material
JP2001163932A (en) 1999-10-27 2001-06-19 Novartis Ag Method for modifying surface of material
WO2001030512A2 (en) 1999-10-27 2001-05-03 Novartis Ag Coating process
JP2001158813A (en) 1999-10-27 2001-06-12 Novartis Ag Method for covering surface of material
ES2328009T5 (en) 1999-12-16 2013-12-12 Coopervision International Holding Company, Lp Soft contact lens with long-term capacity
US6465602B2 (en) 2000-01-20 2002-10-15 Kimberly-Clark Worldwide, Inc. Modified condensation polymers having azetidinium groups and containing polysiloxane moieties
US6793973B2 (en) 2000-02-04 2004-09-21 Novartis Ag Single-dip process for achieving a layer-by-layer-like coating
US6719929B2 (en) 2000-02-04 2004-04-13 Novartis Ag Method for modifying a surface
JP3929014B2 (en) 2000-02-24 2007-06-13 Ｈｏｙａヘルスケア株式会社 Contact lens material comprising a macromer having a polysiloxane structure in the side chain
US7521519B1 (en) 2000-03-14 2009-04-21 Novartis Ag Organic compounds
GB0006891D0 (en) 2000-03-23 2000-05-10 Arjobex Ltd Coating composition
CA2401865C (en) 2000-03-24 2010-01-12 Novartis Ag Crosslinkable or polymerizable prepolymers
US6923538B2 (en) 2000-07-06 2005-08-02 Coopervision, Inc. Method for cast moulding contact lenses with a rounded edge form
US6467903B1 (en) 2000-03-31 2002-10-22 Ocular Sciences, Inc. Contact lens having a uniform horizontal thickness profile
US6599559B1 (en) 2000-04-03 2003-07-29 Bausch & Lomb Incorporated Renewable surface treatment of silicone medical devices with reactive hydrophilic polymers
US6689480B2 (en) 2000-05-10 2004-02-10 Toray Industries, Inc. Surface-treated plastic article and method of surface treatment
US6589665B2 (en) 2000-05-30 2003-07-08 Novartis Ag Coated articles
US6428839B1 (en) 2000-06-02 2002-08-06 Bausch & Lomb Incorporated Surface treatment of medical device
US6364934B1 (en) 2000-07-31 2002-04-02 Bausch & Lomb Incorporated Method of making ocular devices
US6482221B1 (en) 2000-08-21 2002-11-19 Counter Clockwise, Inc. Manipulatable delivery catheter for occlusive devices (II)
WO2002015911A1 (en) 2000-08-22 2002-02-28 Nof Corporation Lubricating agent and insertion aid solution for contact lens
US6852353B2 (en) 2000-08-24 2005-02-08 Novartis Ag Process for surface modifying substrates and modified substrates resulting therefrom
SK2152003A3 (en) * 2000-08-24 2003-08-05 Novartis Ag Process for surface modifying substrates and modified substrates resulting therefrom
BR0114212A (en) 2000-09-19 2003-12-23 Bausch & Lomb Incoporated Method for treating the surface of a medical device
US6551267B1 (en) 2000-10-18 2003-04-22 Becton, Dickinson And Company Medical article having blood-contacting surface
US20020182315A1 (en) 2000-11-01 2002-12-05 Heiler David J. Surface treatment of non-plasma treated silicone hydrogel contact lenses
DE10055762A1 (en) 2000-11-10 2002-06-06 Woehlk Contact Linsen Gmbh Hydrogel contact lenses with high biocompatibility
US6531432B2 (en) 2000-12-07 2003-03-11 Johnson & Johnson Vision Care, Inc. Contact lens packaging solutions
JP4043789B2 (en) 2001-01-24 2008-02-06 ノバルティス アクチエンゲゼルシャフト Method for modifying a surface
US6835410B2 (en) 2001-05-21 2004-12-28 Novartis Ag Bottle-brush type coatings with entangled hydrophilic polymer
JP2003066381A (en) 2001-05-23 2003-03-05 Novartis Ag System and method for processing object with liquid
US6811805B2 (en) 2001-05-30 2004-11-02 Novatis Ag Method for applying a coating
US7879267B2 (en) 2001-08-02 2011-02-01 J&J Vision Care, Inc. Method for coating articles by mold transfer
US6891010B2 (en) 2001-10-29 2005-05-10 Bausch & Lomb Incorporated Silicone hydrogels based on vinyl carbonate endcapped fluorinated side chain polysiloxanes
TW200407367A (en) 2001-11-13 2004-05-16 Novartis Ag Method for modifying the surface of biomedical articles
TWI255224B (en) 2002-01-09 2006-05-21 Novartis Ag Polymeric articles having a lubricious coating and method for making the same
GB0201165D0 (en) 2002-01-18 2002-03-06 Unilever Plc Azetidinium modidfied poymers and fabric treatment composition
US6936641B2 (en) 2002-06-25 2005-08-30 Johnson & Johnson Vision Care, Inc. Macromer forming catalysts
US7270678B2 (en) 2002-06-28 2007-09-18 Bausch & Lomb Incorporated Surface modification of functional group-containing medical devices with catalyst-containing reactive polymer system
US7428029B2 (en) 2002-07-30 2008-09-23 Nitto Denko Corporation Optical film and its manufacturing method
AU2002950469A0 (en) 2002-07-30 2002-09-12 Commonwealth Scientific And Industrial Research Organisation Improved biomedical compositions
DE60317797T2 (en) 2002-08-14 2008-10-30 Novartis Ag RADIATION-HARDENABLE PREPOLYMERS
US20080299179A1 (en) 2002-09-06 2008-12-04 Osman Rathore Solutions for ophthalmic lenses containing at least one silicone containing component
US6926965B2 (en) 2002-09-11 2005-08-09 Novartis Ag LbL-coated medical device and method for making the same
US6896926B2 (en) 2002-09-11 2005-05-24 Novartis Ag Method for applying an LbL coating onto a medical device
US6740336B2 (en) 2002-10-04 2004-05-25 Mirus Corporation Process for generating multilayered particles
US20040116564A1 (en) 2002-11-27 2004-06-17 Devlin Brian Gerrard Stabilization of poly(oxyalkylene) containing polymeric materials
US8172395B2 (en) 2002-12-03 2012-05-08 Novartis Ag Medical devices having antimicrobial coatings thereon
US7032251B2 (en) 2002-12-10 2006-04-25 Kimberly-Clark Worldwide, Inc. Crosslinking agent for coated elastomeric articles
US7384590B2 (en) 2002-12-17 2008-06-10 Novartis Ag System and method for curing polymeric moldings
US7387759B2 (en) 2002-12-17 2008-06-17 Novartis Ag System and method for curing polymeric moldings having a masking collar
CN100529842C (en) 2003-01-10 2009-08-19 株式会社美你康 Highly safe silicone-containing material for ocular lens and process for producing the same
WO2004075943A1 (en) 2003-02-28 2004-09-10 Biointeractions Ltd. Polymeric network system for medical devices and methods of use
EP1623269B2 (en) 2003-04-24 2022-08-31 CooperVision International Limited Hydrogel contact lenses and package systems and production methods for same
GB0322640D0 (en) 2003-09-26 2003-10-29 1800 Contacts Process
US7977430B2 (en) 2003-11-25 2011-07-12 Novartis Ag Crosslinkable polyurea prepolymers
US7084188B2 (en) 2003-12-05 2006-08-01 Bausch & Lomb Incorporated Surface modification of contact lenses
US7214809B2 (en) 2004-02-11 2007-05-08 Johnson & Johnson Vision Care, Inc. (Meth)acrylamide monomers containing hydroxy and silicone functionalities
DE602004029615D1 (en) 2004-05-28 2010-11-25 Menicon Co Ltd CONTACT LENS
SG155241A1 (en) 2004-08-27 2009-09-30 Asahikasei Aime Co Ltd Silicone hydrogel contact lenses
JP4782508B2 (en) 2004-09-30 2011-09-28 株式会社シード High oxygen permeation hydrous ophthalmic lens
US7249848B2 (en) 2004-09-30 2007-07-31 Johnson & Johnson Vision Care, Inc. Wettable hydrogels comprising reactive, hydrophilic, polymeric internal wetting agents
US7247692B2 (en) 2004-09-30 2007-07-24 Johnson & Johnson Vision Care, Inc. Biomedical devices containing amphiphilic block copolymers
US7556858B2 (en) 2004-09-30 2009-07-07 3M Innovative Properties Company Substrate with attached dendrimers
US20060065138A1 (en) 2004-09-30 2006-03-30 Tucker Robert C Pad printing method for making colored contact lenses
ATE452659T1 (en) 2004-10-01 2010-01-15 Menicon Co Ltd METHOD FOR STERILIZING PACKAGED CONTACT LENSES WITH PACKAGING SOLUTION
US7857447B2 (en) 2004-10-05 2010-12-28 The Board Of Trustees Of The Leland Stanford Junior University Interpenetrating polymer network hydrogel contact lenses
US20060100113A1 (en) 2004-11-05 2006-05-11 Pegram Stephen C Methods of inhabiting the adherence of lenses to surfaces during their manufacture
JP5324100B2 (en) 2004-11-29 2013-10-23 ディーエスエム アイピー アセッツ ビー．ブイ． Method for reducing the amount of migratory substances contained in a polymer coating
SE0403092D0 (en) 2004-12-20 2004-12-20 Amo Groningen Bv Amphiphilic block copolymers and their use
CA2593070A1 (en) 2004-12-29 2006-07-06 Bausch & Lomb Incorporated Polysiloxane prepolymers for biomedical devices
JP4933448B2 (en) 2004-12-29 2012-05-16 ボーシュ アンド ローム インコーポレイティド Polysiloxane prepolymer for biomedical devices
EP1861069B2 (en) 2005-02-09 2013-07-03 Safilens S.R.L. Contact lens, method for producing same, and pack for storage and maintenance of a contact lens
CN103933614B (en) 2005-02-14 2016-03-02 庄臣及庄臣视力保护公司 Comfortable ophthalmic device and manufacture method thereof
US7426993B2 (en) 2005-08-09 2008-09-23 Coopervision International Holding Company, Lp Contact lens package
CA2618035A1 (en) 2005-08-10 2007-02-15 Novartis Ag Silicone hydrogels
BRPI0614244A2 (en) 2005-08-11 2011-03-15 Coopervision Int Holding Co Lp Contact Lenses and Methods to Reduce Conjunctival Pressure in Contact Lens Users
EP1754731A1 (en) 2005-08-16 2007-02-21 Nederlandse Organisatie voor Toegepast-Natuuurwetenschappelijk Onderzoek TNO Method of modifying materials surfaces
BRPI0618567A2 (en) 2005-11-14 2011-09-06 Ciba Holding Inc preparation of functionalized cationic polymers and their preparation and application in personal care
WO2007064594A2 (en) 2005-11-29 2007-06-07 Bausch & Lomb Incorporated New coatings on ophthalmic lenses
US20070149428A1 (en) 2005-12-14 2007-06-28 Bausch & Lomb Incorporated Method of Packaging a Lens
US7825273B2 (en) 2006-01-06 2010-11-02 Bausch & Lomb Incorporated Process for making cationic hydrophilic siloxanyl monomers
US8044112B2 (en) * 2006-03-30 2011-10-25 Novartis Ag Method for applying a coating onto a silicone hydrogel lens
WO2007121513A1 (en) 2006-04-20 2007-11-01 Aortech Biomaterials Pty Ltd Gels
US7789509B2 (en) 2006-06-01 2010-09-07 Advanced Vision Science, Inc. Non- or reduced glistenings intraocular lens and method of manufacturing same
US7858000B2 (en) 2006-06-08 2010-12-28 Novartis Ag Method of making silicone hydrogel contact lenses
US7540609B2 (en) 2006-06-15 2009-06-02 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
US8231218B2 (en) 2006-06-15 2012-07-31 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
US7572841B2 (en) 2006-06-15 2009-08-11 Coopervision International Holding Company, Lp Wettable silicone hydrogel contact lenses and related compositions and methods
US7960465B2 (en) 2006-06-30 2011-06-14 Johnson & Johnson Vision Care, Inc. Antimicrobial lenses, processes to prepare them and methods of their use
US20080003259A1 (en) 2006-06-30 2008-01-03 Salamone Joseph C Modification of surfaces of polymeric articles by Michael addition reaction
TWI441835B (en) 2006-07-12 2014-06-21 Novartis Ag Novel polymers
US8459445B2 (en) 2006-07-21 2013-06-11 Menicon, Co., Ltd. Colored contact lens primary packaging
EP1905415B1 (en) 2006-09-27 2009-07-01 Ivoclar Vivadent AG Polymerisable compositions comprising acyl-germanium as initiators
EP2089069B1 (en) 2006-10-30 2016-01-27 Novartis AG Method for applying a coating onto a silicone hydrogel lens
RU2450802C2 (en) 2006-11-06 2012-05-20 Новартис Аг Ophthalmic devices and methods for making and using them
US20080110770A1 (en) 2006-11-10 2008-05-15 Bausch & Lomb Incorporated Packaging solutions
GB0623299D0 (en) 2006-11-22 2007-01-03 Sauflon Cl Ltd Contact lens
TWI434926B (en) 2006-12-11 2014-04-21 Alcon Res Ltd Use of peo-pbo block copolymers in ophthalmic compositions
EP2091979A2 (en) 2006-12-13 2009-08-26 Novartis AG Actinically curable silicone hydrogel copolymers and uses thereof
AR064286A1 (en) 2006-12-13 2009-03-25 Quiceno Gomez Alexandra Lorena PRODUCTION OF OPHTHALMIC DEVICES BASED ON POLYMERIZATION BY PHOTOINDUCIDED SCALE GROWTH
DE602007011317D1 (en) 2006-12-15 2011-01-27 Bausch & Lomb SURFACE TREATMENT OF BIOMEDICAL DEVICES
US20080141628A1 (en) 2006-12-15 2008-06-19 Bausch & Lomb Incorporated Packaging Solutions
US20080142038A1 (en) 2006-12-15 2008-06-19 Bausch & Lomb Incorporated Surface treatment of medical devices
US20080148689A1 (en) 2006-12-20 2008-06-26 Bausch & Lomb Incorporated Packaging solutions
US7832856B2 (en) 2006-12-20 2010-11-16 Bausch & Lomb Incorporated Coatings and solutions for contact lenses
JP5473605B2 (en) 2006-12-21 2014-04-16 ノバルティス アーゲー Method for coating biomedical articles
US20080152540A1 (en) 2006-12-22 2008-06-26 Bausch & Lomb Incorporated Packaging solutions
ATE481435T1 (en) 2007-01-12 2010-10-15 Dow Corning COMPOSITION CONTAINING SILICONE
US8147897B2 (en) * 2007-02-09 2012-04-03 Novartis Ag Cross-linkable polyionic coatings for medical devices
MX2009010116A (en) 2007-03-22 2009-10-12 Novartis Ag Prepolymers with dangling polysiloxane-containing polymer chains.
JP5653624B2 (en) 2007-03-22 2015-01-14 ノバルティス アーゲー Silicone-containing prepolymer having hydrophilic polymer chains
US7691917B2 (en) 2007-06-14 2010-04-06 Bausch & Lomb Incorporated Silcone-containing prepolymers
US20080314767A1 (en) 2007-06-22 2008-12-25 Bausch & Lomb Incorporated Ophthalmic Solutions
US7868071B2 (en) 2007-07-30 2011-01-11 Georgia-Pacific Chemicals Llc Method of stabilizing aqueous cationic polymers
JP5643092B2 (en) 2007-08-31 2014-12-17 ノバルティス アーゲー Contact lens packaging solution
US8490782B2 (en) 2007-10-23 2013-07-23 Bausch & Lomb Incorporated Packaging solutions
US20090111942A1 (en) 2007-10-25 2009-04-30 Bausch & Lomb Incorporated Method for Making Surface Modified Biomedical Devices
WO2009070429A1 (en) 2007-11-29 2009-06-04 Bausch & Lomb Incorporated Process for making biomedical devices
WO2009070443A1 (en) 2007-11-29 2009-06-04 Bausch & Lomb Incorporated Process for making biomedical devices
US7934830B2 (en) 2007-12-03 2011-05-03 Bausch & Lomb Incorporated High water content silicone hydrogels
US20090145091A1 (en) 2007-12-11 2009-06-11 Richard Connolly Method for treating ophthalmic lenses
US20090145086A1 (en) 2007-12-11 2009-06-11 Reynolds Ger M Method for treating ophthalmic lenses
RU2488863C2 (en) 2007-12-20 2013-07-27 Новартис Аг Method of making contact lenses
US20090171049A1 (en) 2007-12-27 2009-07-02 Linhardt Jeffrey G Segmented reactive block copolymers
US20090173643A1 (en) 2008-01-09 2009-07-09 Yu-Chin Lai Packaging Solutions
US7837934B2 (en) 2008-01-09 2010-11-23 Bausch & Lomb Incorporated Packaging solutions
US20090173045A1 (en) 2008-01-09 2009-07-09 Yu-Chin Lai Packaging Solutions
WO2009091728A2 (en) 2008-01-14 2009-07-23 Coopervision International Holding Company, Lp Polymerizable contact lens formulations and contact lenses obtained therefrom
US8142835B2 (en) 2008-01-23 2012-03-27 Novartis Ag Method for coating silicone hydrogels
US7781554B2 (en) 2008-03-05 2010-08-24 Bausch & Lomb Incorporated Polysiloxanes and polysiloxane prepolymers with vinyl or epoxy functionality
MY152305A (en) 2008-03-18 2014-09-15 Novartis Ag Coating process for ophthalmic lenses
US8470906B2 (en) 2008-09-30 2013-06-25 Johnson & Johnson Vision Care, Inc. Ionic silicone hydrogels having improved hydrolytic stability
US8246168B2 (en) 2008-11-10 2012-08-21 Bausch & Lomb Incorporated Methacrylate-based bulky side-chain siloxane cross linkers for optical medical devices
US20100149482A1 (en) 2008-12-12 2010-06-17 Ammon Jr Daniel M Contact lens
CN103969706B (en) 2008-12-18 2017-08-25 诺华股份有限公司 Lens forming composition suitable for manufacturing silicone hydrogel contact lens
WO2010077708A1 (en) 2008-12-30 2010-07-08 Bausch & Lomb Incorporated Packaging solutions
US8534031B2 (en) 2008-12-30 2013-09-17 Bausch & Lomb Incorporated Packaging solutions
US8642712B2 (en) 2009-05-22 2014-02-04 Novartis Ag Actinically-crosslinkable siloxane-containing copolymers
US8383744B2 (en) 2009-05-22 2013-02-26 Novartis Ag Actinically-crosslinkable siloxane-containing copolymers
JP5800369B2 (en) 2009-07-09 2015-10-28 ボシュ・アンド・ロム・インコーポレイテッドＢａｕｓｃｈ ＆ Ｌｏｍｂ Ｉｎｃｏｒｐｏｒａｔｅｄ Monoethylenically unsaturated polymerizable group-containing polycarbosiloxane monomer
US7915323B2 (en) 2009-07-09 2011-03-29 Bausch & Lamb Incorporated Mono ethylenically unsaturated polycarbosiloxane monomers
MY156206A (en) 2009-11-04 2016-01-29 Novartis Ag A silicone hydrogel lens with a grafted hydrophilic coating
TWI483996B (en) 2009-12-08 2015-05-11 Novartis Ag A silicone hydrogel lens with a covalently attached coating
ES2593615T3 (en) 2010-07-30 2016-12-12 Novartis Ag Polysiloxane amphiphilic prepolymers and uses thereof
KR102411923B1 (en) 2010-07-30 2022-06-22 알콘 인코포레이티드 Silicone hydrogel lenses with water-rich surfaces
SG190218A1 (en) 2010-11-10 2013-06-28 Novartis Ag Method for making contact lenses
US8772367B2 (en) 2011-03-21 2014-07-08 Momentive Performance Materials Inc. Siloxane monomers containing hydrolysis resistance carbosiloxane linkage, process for their preparation and thin films containing the same for contact lens application
US10391179B2 (en) 2011-03-21 2019-08-27 Momentive Performance Materials Inc. Organomodified carbosiloxane monomers containing compositions and uses thereof
EP2780748B1 (en) 2011-11-15 2016-01-13 Novartis AG A silicone hydrogel lens with a crosslinked hydrophilic coating
EP3134461B1 (en) 2014-04-25 2018-02-14 Novartis AG Hydrophilized carbosiloxane vinylic monomers
EP3134420B1 (en) 2014-04-25 2019-01-30 Novartis AG Carbosiloxane vinylic monomers

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