KR102233537B1 - 항균성 폴리아미드 조성물 및 유방염 치료 - Google Patents

항균성 폴리아미드 조성물 및 유방염 치료 Download PDF

Info

Publication number
KR102233537B1
KR102233537B1 KR1020157029866A KR20157029866A KR102233537B1 KR 102233537 B1 KR102233537 B1 KR 102233537B1 KR 1020157029866 A KR1020157029866 A KR 1020157029866A KR 20157029866 A KR20157029866 A KR 20157029866A KR 102233537 B1 KR102233537 B1 KR 102233537B1
Authority
KR
South Korea
Prior art keywords
veterinary composition
composition
dissolved
veterinary
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020157029866A
Other languages
English (en)
Korean (ko)
Other versions
KR20150131354A (ko
Inventor
수잔 만치니 케이디
이자벨라 갈레스카
프라딥 케이 달
Original Assignee
뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드
젠자임 코포레이션
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드, 젠자임 코포레이션 filed Critical 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드
Publication of KR20150131354A publication Critical patent/KR20150131354A/ko
Application granted granted Critical
Publication of KR102233537B1 publication Critical patent/KR102233537B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A61K31/787—Polymers containing nitrogen containing heterocyclic rings having nitrogen as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/26—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from polyamines and polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/16—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with acylated ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • C08G63/668—Polyesters containing oxygen in the form of ether groups derived from polycarboxylic acids and polyhydroxy compounds
    • C08G63/672—Dicarboxylic acids and dihydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/0273—Polyamines containing heterocyclic moieties in the main chain
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/02—Polyamines
    • C08G73/028—Polyamidoamines
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/0622—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms
    • C08G73/0627—Polycondensates containing six-membered rings, not condensed with other rings, with nitrogen atoms as the only ring hetero atoms with only one nitrogen atom in the ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Polyamides (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
KR1020157029866A 2013-03-15 2014-03-11 항균성 폴리아미드 조성물 및 유방염 치료 Active KR102233537B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361790231P 2013-03-15 2013-03-15
US61/790,231 2013-03-15
PCT/US2014/023299 WO2014150451A1 (en) 2013-03-15 2014-03-11 Antimicrobial polyamide compositions and mastitis treatment

Publications (2)

Publication Number Publication Date
KR20150131354A KR20150131354A (ko) 2015-11-24
KR102233537B1 true KR102233537B1 (ko) 2021-03-29

Family

ID=50390295

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1020157028805A Ceased KR20150132325A (ko) 2013-03-15 2014-03-11 아민 작용성 폴리아미드
KR1020157029866A Active KR102233537B1 (ko) 2013-03-15 2014-03-11 항균성 폴리아미드 조성물 및 유방염 치료

Family Applications Before (1)

Application Number Title Priority Date Filing Date
KR1020157028805A Ceased KR20150132325A (ko) 2013-03-15 2014-03-11 아민 작용성 폴리아미드

Country Status (22)

Country Link
US (3) US10131744B2 (enExample)
EP (2) EP2970586B1 (enExample)
JP (4) JP7000021B2 (enExample)
KR (2) KR20150132325A (enExample)
CN (2) CN105189607B (enExample)
AR (1) AR095366A1 (enExample)
AU (2) AU2014237169B2 (enExample)
BR (1) BR112015022224A2 (enExample)
CA (2) CA2907045C (enExample)
CL (1) CL2015002762A1 (enExample)
EA (1) EA030750B1 (enExample)
ES (1) ES2835382T3 (enExample)
HK (1) HK1220711A1 (enExample)
IL (1) IL241405A0 (enExample)
MX (2) MX373164B (enExample)
NZ (1) NZ712876A (enExample)
RU (1) RU2644554C2 (enExample)
SG (1) SG11201506359UA (enExample)
TW (2) TWI624263B (enExample)
UA (1) UA119642C2 (enExample)
WO (2) WO2014150338A1 (enExample)
ZA (1) ZA201506808B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG11201506359UA (en) 2013-03-15 2015-09-29 Genzyme Corp Amine functional polyamides
MX2017000447A (es) * 2014-07-11 2017-04-27 Genzyme Corp Poliaminas de cadena principal.
CN104292148A (zh) * 2014-09-22 2015-01-21 西南科技大学 一种橡胶或树脂光稳定剂的制备方法
WO2017007648A1 (en) * 2015-07-09 2017-01-12 Henkel IP & Holding GmbH Low viscosity transparent polyamide
CA3002214C (en) * 2015-11-03 2022-01-04 Zoetis Services Llc Sol-gel polymer composites and uses thereof
CA3020634C (en) 2016-04-14 2025-06-17 Genzyme Corporation MULTIDOSE COMPOSITIONS CONTAINING AN ANTIMICROBIAL PRESERVATIVE BASED ON POLYAMIDE OR OCTENIDINE
KR20190018317A (ko) * 2017-08-14 2019-02-22 한국생명공학연구원 모노아세틸디아실글리세롤 화합물을 함유하는 슈도모나스 속 미생물 감염증의 예방 또는 치료용 조성물
US10743537B2 (en) 2017-12-12 2020-08-18 International Business Machines Corporation Monomer compositions with antimicrobial functionality
US10653142B2 (en) 2017-12-12 2020-05-19 International Business Machines Corporation Polymers with antimicrobial functionalities
US10595527B2 (en) 2017-12-12 2020-03-24 International Business Machines Corporation Antimicrobial polymers capable of supramolecular assembly
US10836864B2 (en) 2017-12-12 2020-11-17 International Business Machines Corporation Chemical compositions with antimicrobial functionality
US10667514B2 (en) 2017-12-12 2020-06-02 International Business Machines Corporation Antimicrobial ionene compositions with a variety of functional groups
US10687528B2 (en) 2017-12-12 2020-06-23 International Business Machines Corporation Antimicrobial polymers with enhanced functionalities
US10687530B2 (en) 2017-12-12 2020-06-23 International Business Machines Corporation Hydrophilic polymers with antimicrobial functionalities
RU2732206C2 (ru) * 2018-12-29 2020-09-14 Вероника Андреевна Гусева Способ лечения маститов у крупного рогатого скота
KR102052086B1 (ko) * 2019-07-25 2019-12-04 복세원 젖소 유두 보호제 및 그 제조방법
CN111471630B (zh) * 2020-06-11 2021-11-02 鲁东大学 一株棒杆菌Ytld-phe09及其应用
CN114796583B (zh) * 2022-03-25 2023-02-10 浙江大学 一种基于聚硫辛酸的生物医用贴片材料及其制备方法
CN115531518B (zh) * 2022-09-22 2023-05-23 湖南科技学院 一种用于防治奶牛乳房炎的中药软膏及其制备方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110209228A1 (en) * 2008-03-13 2011-08-25 Benjamin Cocks Method of treatment using antimicrobial composition
CA2828998A1 (en) 2011-03-04 2012-09-13 Beijing Created Tribiotechnology Co., Ltd. Preparation method of new recombinant antibacterial polypeptide medicine

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583946A (en) * 1969-04-24 1971-06-08 Monsanto Co Polyureas derived from dipiperidines
IT981412B (it) * 1973-03-15 1974-10-10 Montedison Spa Poliammidi da acidi eterociclici aromatici ortocarbossilici e pro cedimento per prepararle
US4070400A (en) * 1975-10-16 1978-01-24 Merck & Co., Inc. Diphenyl polyamides having a cyclohexylene moiety
DE2942680C2 (de) * 1979-10-23 1986-02-27 Schering AG, 1000 Berlin und 4709 Bergkamen Schmelzkleber auf Basis von Polyesteramiden und deren Verwendung zum Verkleben von organischen und anorganischen Substraten
JPS591531A (ja) * 1982-06-25 1984-01-06 Daicel Chem Ind Ltd 感温性高分子材料
JPS596220A (ja) * 1982-07-01 1984-01-13 Daicel Chem Ind Ltd 新規ポリアミド共重合体
US4462942A (en) * 1982-07-30 1984-07-31 Eli Lilly And Company A47934 Antibiotic and process for production thereof
JPH01252633A (ja) * 1987-12-03 1989-10-09 Ricoh Co Ltd ポリアミドを用いた熱転写記録媒体及び新規なポリアミド
JPH0228208A (ja) * 1988-04-28 1990-01-30 Japan Synthetic Rubber Co Ltd 感放射線性共重合体およびその製造方法
JPH03258832A (ja) * 1990-03-08 1991-11-19 Mitsubishi Kasei Corp 不飽和ポリアミド
US6369049B1 (en) * 1998-04-30 2002-04-09 Eli Lilly And Company Treatment of mastitis
US6203812B1 (en) * 1998-06-29 2001-03-20 Hydromer, Inc. Hydrophilic polymer blends used to prevent cow skin infections
AUPP584298A0 (en) * 1998-09-14 1998-10-08 Starpharma Limited Antimicrobial and antiparasitic agents
US20020009491A1 (en) * 2000-02-14 2002-01-24 Rothbard Jonathan B. Compositions and methods for enhancing drug delivery across biological membranes and tissues
PT1395289E (pt) * 2000-06-08 2011-03-16 Sang Dr Christine Tratamento da dor neuropática com antagonistas do receptor de n-metil-d-aspartato (nmda)
DK1292327T3 (da) * 2000-06-12 2007-08-06 Univ Saskatchewan Immunisering af malkekvæg med Mig protein
US6998115B2 (en) * 2000-10-10 2006-02-14 Massachusetts Institute Of Technology Biodegradable poly(β-amino esters) and uses thereof
GB0029004D0 (en) * 2000-11-28 2001-01-10 Pharmacia & Upjohn Spa Process for preparing distamycin derivatives
US20040013698A1 (en) * 2001-07-09 2004-01-22 Aust Duncan T Method for preparing topical preparations containing skin protective agents with enhanced barrier properties
WO2004046109A2 (en) * 2002-11-19 2004-06-03 Genzyme Corporation Ionene oligomers and polymers
DE102004054873A1 (de) * 2004-11-12 2006-05-18 Bayer Healthcare Ag Behandlung von Mastitis
EP2138171A1 (en) * 2008-06-18 2009-12-30 Istituto Superiore Di Sanita' Veterinarian compositions containing terpinen-4-ol for the treatment and prevention of mastitis
JP5599808B2 (ja) * 2008-11-07 2014-10-01 ノバベイ・ファーマシューティカルズ・インコーポレイテッド 抗菌性ｎ−塩素化組成物
JP5808082B2 (ja) * 2010-04-30 2015-11-10 株式会社Adeka 細胞への水溶性高分子量物質の導入方法及び導入剤
US8758778B2 (en) 2010-09-16 2014-06-24 The Regents Of The University Of California Polymeric nano-carriers with a linear dual response mechanism and uses thereof
WO2012151555A1 (en) 2011-05-04 2012-11-08 President And Fellows Of Harvard College Methods and coatings for treating biofilms
AU2012255935B2 (en) 2011-05-16 2016-06-23 Innovation Pharmaceuticals Inc. Compounds for use in treatment of mucositis
KR20150030707A (ko) 2012-06-29 2015-03-20 바이엘 애니멀 헬스 게엠베하 약학 조성물 및 유방염 치료
SG11201506359UA (en) 2013-03-15 2015-09-29 Genzyme Corp Amine functional polyamides

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110209228A1 (en) * 2008-03-13 2011-08-25 Benjamin Cocks Method of treatment using antimicrobial composition
CA2828998A1 (en) 2011-03-04 2012-09-13 Beijing Created Tribiotechnology Co., Ltd. Preparation method of new recombinant antibacterial polypeptide medicine

Also Published As

Publication number Publication date
ES2835382T3 (es) 2021-06-22
JP2016516700A (ja) 2016-06-09
RU2015144224A (ru) 2017-04-21
EP2970586B1 (en) 2022-12-07
BR112015023445A2 (enExample) 2017-08-29
EP2968231B1 (en) 2020-07-01
US20140275469A1 (en) 2014-09-18
EP2968231A1 (en) 2016-01-20
BR112015022224A2 (pt) 2017-07-18
US9326994B2 (en) 2016-05-03
MX364611B (es) 2019-05-02
MX2015012119A (es) 2016-05-18
US20140271526A1 (en) 2014-09-18
US10131744B2 (en) 2018-11-20
HK1215537A1 (zh) 2016-09-02
TWI624263B (zh) 2018-05-21
KR20150131354A (ko) 2015-11-24
AR095366A1 (es) 2015-10-14
MX2015013262A (es) 2016-04-04
HK1220711A1 (zh) 2017-05-12
JP7000021B2 (ja) 2022-01-19
EA030750B1 (ru) 2018-09-28
AU2014237232B9 (en) 2018-02-01
CN105189607B (zh) 2018-06-15
EP2970586A1 (en) 2016-01-20
JP2020045493A (ja) 2020-03-26
CA2906334C (en) 2023-03-14
WO2014150338A1 (en) 2014-09-25
KR20150132325A (ko) 2015-11-25
CA2906334A1 (en) 2014-09-25
US20160208046A1 (en) 2016-07-21
TWI667028B (zh) 2019-08-01
CN105338976B (zh) 2018-12-04
JP2016514192A (ja) 2016-05-19
AU2014237232B2 (en) 2018-01-18
CN105189607A (zh) 2015-12-23
AU2014237169A1 (en) 2015-10-29
TW201513873A (zh) 2015-04-16
SG11201506359UA (en) 2015-09-29
EA201591812A1 (ru) 2016-02-29
WO2014150451A1 (en) 2014-09-25
UA119642C2 (uk) 2019-07-25
BR112015023445A8 (pt) 2022-06-28
TW201513872A (zh) 2015-04-16
CA2907045C (en) 2020-12-08
JP6359630B2 (ja) 2018-07-18
RU2644554C2 (ru) 2018-02-13
JP2018188662A (ja) 2018-11-29
CA2907045A1 (en) 2014-09-25
MX373164B (es) 2020-05-07
US10113032B2 (en) 2018-10-30
AU2014237232A1 (en) 2015-10-22
IL241405A0 (en) 2015-11-30
NZ712876A (en) 2016-09-30
CL2015002762A1 (es) 2016-04-08
AU2014237169B2 (en) 2017-02-16
CN105338976A (zh) 2016-02-17
ZA201506808B (en) 2017-11-29

Similar Documents

Publication Publication Date Title
KR102233537B1 (ko) 항균성 폴리아미드 조성물 및 유방염 치료
KR101478728B1 (ko) 안과 및 수의 안과에서 사용하기 위한 약학적 조성물
JP5745666B2 (ja) 面状両親媒性ポリマー及びオリゴマーの眼科用及び耳科用組成物とその使用
US7622138B2 (en) Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
EA023208B1 (ru) Фармацевтические композиции, которые содержат имидазохинолин(амины) и их производные, пригодные для местного введения
JP2005511642A5 (enExample)
CN105492005A (zh) 治疗包括乳房炎的微生物感染的方法
JP2022164840A (ja) 眼科組成物
CN103379904A (zh) 具有保存效能的溴芬酸水性液剂组合物
JP6255134B1 (ja) 耳炎の治療のための組成物および方法
BR112015023445B1 (pt) Composições de poliamida antimicrobiana e tratamento de mastite
US20170071979A1 (en) Composition and method for treating otitis
JP7644075B2 (ja) 眼科組成物
JP2012523450A (ja) 硫酸フラミセチンクリーム剤およびキトサンを使用して製造された薬用クリーム剤ならびにそれを製造する方法
EP4267146B1 (en) An orthosomycin antimicrobial compound for use in methods of treating mastitis
CN102497854A (zh) 含有作为防腐剂的丙酸衍生物的眼用液体药物组合物
CA3240070A1 (en) Method and composition for treating infectious conjunctivitis
BR112018067570B1 (pt) Composições antimicrobianas contendo poliquatérnio

Legal Events

Date Code Title Description
PA0105 International application

Patent event date: 20151015

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 20180509

Comment text: Request for Examination of Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20190704

Patent event code: PE09021S01D

PN2301 Change of applicant

Patent event date: 20190920

Comment text: Notification of Change of Applicant

Patent event code: PN23011R01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20200130

Patent event code: PE09021S01D

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 20200729

Patent event code: PE09021S01D

E701 Decision to grant or registration of patent right
PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 20201223

GRNT Written decision to grant
PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 20210324

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 20210324

End annual number: 3

Start annual number: 1

PG1601 Publication of registration
PR1001 Payment of annual fee

Payment date: 20240315

Start annual number: 4

End annual number: 4