KR101829290B1 - Gpr120 효능제로서의 바이아릴 유도체 - Google Patents

Gpr120 효능제로서의 바이아릴 유도체 Download PDF

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KR101829290B1
KR101829290B1 KR1020150185417A KR20150185417A KR101829290B1 KR 101829290 B1 KR101829290 B1 KR 101829290B1 KR 1020150185417 A KR1020150185417 A KR 1020150185417A KR 20150185417 A KR20150185417 A KR 20150185417A KR 101829290 B1 KR101829290 B1 KR 101829290B1
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phenyl
difluoro
acid
acetic acid
rti
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KR20160078286A (ko
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김영관
박상연
주현우
최은실
백승엽
강승완
김병규
이창석
김성욱
이상대
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주식회사 엘지화학
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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