KR101523698B1 - 사람 암 줄기세포 - Google Patents
사람 암 줄기세포 Download PDFInfo
- Publication number
- KR101523698B1 KR101523698B1 KR1020097017268A KR20097017268A KR101523698B1 KR 101523698 B1 KR101523698 B1 KR 101523698B1 KR 1020097017268 A KR1020097017268 A KR 1020097017268A KR 20097017268 A KR20097017268 A KR 20097017268A KR 101523698 B1 KR101523698 B1 KR 101523698B1
- Authority
- KR
- South Korea
- Prior art keywords
- stem cells
- cells
- cell
- cancer stem
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88149707P | 2007-01-22 | 2007-01-22 | |
| US60/881,497 | 2007-01-22 | ||
| US90718007P | 2007-03-23 | 2007-03-23 | |
| US60/907,180 | 2007-03-23 | ||
| US92424707P | 2007-05-04 | 2007-05-04 | |
| US60/924,247 | 2007-05-04 | ||
| US95071407P | 2007-07-19 | 2007-07-19 | |
| US60/950,714 | 2007-07-19 | ||
| US97261307P | 2007-09-14 | 2007-09-14 | |
| US60/972,613 | 2007-09-14 | ||
| PCT/US2008/051730 WO2008091908A2 (en) | 2007-01-22 | 2008-01-22 | Human cancer stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20100033471A KR20100033471A (ko) | 2010-03-30 |
| KR101523698B1 true KR101523698B1 (ko) | 2015-05-29 |
Family
ID=39641454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097017268A Expired - Fee Related KR101523698B1 (ko) | 2007-01-22 | 2008-01-22 | 사람 암 줄기세포 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8309354B2 (https=) |
| EP (1) | EP2109668A4 (https=) |
| JP (1) | JP2010516259A (https=) |
| KR (1) | KR101523698B1 (https=) |
| CN (1) | CN101855339A (https=) |
| AU (1) | AU2008207945A1 (https=) |
| CA (1) | CA2675521C (https=) |
| IL (1) | IL199836A (https=) |
| WO (1) | WO2008091908A2 (https=) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2675521C (en) | 2007-01-22 | 2016-04-26 | Raven Biotechnologies | Human cancer stem cells |
| EP3118326B1 (en) | 2008-10-27 | 2020-04-29 | Sapporo Medical University | Molecular marker for cancer stem cell |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| EP2517555A4 (en) | 2009-12-25 | 2014-09-24 | Chugai Pharmaceutical Co Ltd | SEARCHING AND SCREENING METHOD FOR A TARGET MOLECULE OF A CANCER WITH A NON-MENTAL ANIMAL MODEL WITH A NO-CANCER LINE OF TRANSPLANTED LINE |
| EP2542256B1 (en) | 2010-03-04 | 2019-05-22 | MacroGenics, Inc. | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| KR20130055591A (ko) * | 2010-04-13 | 2013-05-28 | 가부시키가이샤 르네상스 에너지 인베스트먼트 | 암 조직 유래 세포괴 또는 암 세포 응집괴로부터 얻어지는 암 치료용 조성물과 그것을 이용한 면역요법제의 제조 방법 및 면역요법 효과 평가 방법 |
| WO2012012803A2 (en) | 2010-07-23 | 2012-01-26 | Advanced Cell Technology, Inc. | Methods for detection of rare subpopulations of cells and highly purified compositions of cells |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| AU2011295715B9 (en) | 2010-09-03 | 2017-02-23 | Abbvie Stemcentrx Llc | Novel modulators and methods of use |
| EP2689787A1 (en) | 2010-09-03 | 2014-01-29 | Stem Centrx, Inc. | Identification and enrichment of cell subpopulations |
| US9778264B2 (en) * | 2010-09-03 | 2017-10-03 | Abbvie Stemcentrx Llc | Identification and enrichment of cell subpopulations |
| JP6230789B2 (ja) * | 2010-10-06 | 2017-11-15 | 中外製薬株式会社 | 癌幹細胞集団及びその作製方法 |
| NZ611428A (en) | 2010-12-08 | 2015-07-31 | Stemcentrx Inc | Novel modulators and methods of use |
| KR101182549B1 (ko) * | 2010-12-16 | 2012-09-12 | 엘지이노텍 주식회사 | 3차원 입체 카메라 모듈 |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| JP6002748B2 (ja) * | 2011-03-24 | 2016-10-05 | ザ・ロゴシン・インスティテュート・インコーポレイテッド | 癌幹細胞の数を選択的に減少させる化合物をスクリーニングするためのアッセイ |
| KR102060389B1 (ko) | 2011-05-21 | 2019-12-31 | 마크로제닉스, 인크. | 사람 및 비-사람 cd3에 결합할 수 있는 cd3-결합 분자 |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| EP2749641B1 (en) | 2011-09-07 | 2021-06-02 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell isolation |
| EP2772268B8 (en) | 2011-10-28 | 2020-01-08 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
| DK2817620T3 (en) | 2012-02-22 | 2016-09-05 | Verik Bio Inc | IMMUNTERY TREATMENT SYSTEM FOR TUMOR FORMATION AND PROGRESSION |
| BR112014020826A8 (pt) | 2012-02-24 | 2017-09-19 | Stem Centrx Inc | Anticorpo que se liga especificamente a um epítopo, ácido nucleico, vetor ou célula hospedeira, conjugado de fármaco anticorpo, composição farmacêutica compreendendo o referido anticorpo, uso do mesmo, kit e método de preparação do conjugado |
| EP3539985A1 (en) | 2012-02-24 | 2019-09-18 | AbbVie Stemcentrx LLC | Anti sez6 antibodies and methods of use |
| JP6090735B2 (ja) * | 2012-03-02 | 2017-03-08 | 国立大学法人山口大学 | 消化器系がん幹細胞を培養するための無血清培地、及びそれを用いた消化器系がん幹細胞の増殖方法 |
| EP2828664B1 (en) * | 2012-03-19 | 2018-09-26 | Stemline Therapeutics Inc. | Methods for treating and monitoring the status of cancer |
| CA3183703A1 (en) | 2012-05-16 | 2013-11-21 | Stemline Therapeutics, Inc. | Cancer stem cell targeted cancer vaccines |
| ES2731681T3 (es) | 2013-02-22 | 2019-11-18 | Abbvie Stemcentrx Llc | Conjugados de anticuerpo anti-DLL3 y PBD y usos de los mismos |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| AU2014248711A1 (en) * | 2013-03-13 | 2015-09-10 | Neostem Oncology, Llc | Individualized high purity colon carcinoma stem cells, methods and use of the same |
| AU2014306778B2 (en) * | 2013-08-12 | 2020-10-29 | Minerva Biotechnologies Corporation | Method for enhancing tumor growth |
| SG11201601424PA (en) | 2013-08-28 | 2016-03-30 | Stemcentrx Inc | Site-specific antibody conjugation methods and compositions |
| CN105792836A (zh) | 2013-08-28 | 2016-07-20 | 施特姆森特克斯股份有限公司 | 新型sez6调节剂以及应用方法 |
| JP6486368B2 (ja) | 2013-09-06 | 2019-03-20 | アカデミア シニカAcademia Sinica | 改変されたグリコシル基を含む糖脂質を用いたヒトiNKT細胞の活性化 |
| RU2016122041A (ru) | 2013-11-06 | 2017-12-11 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Новые анти-клаудин антитела и способы их применения |
| SG11201604664PA (en) | 2013-12-12 | 2016-07-28 | Stemcentrx Inc | Novel anti-dpep3 antibodies and methods of use |
| CA2939941A1 (en) | 2014-02-21 | 2015-08-27 | Abbvie Stemcentrx Llc | Anti-dll3 antibodies and drug conjugates for use in melanoma |
| CA2950415A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-cd20 glycoantibodies and uses thereof |
| JP7093612B2 (ja) | 2014-05-27 | 2022-06-30 | アカデミア シニカ | Bacteroides由来のフコシダーゼおよびそれを使用する方法 |
| CN106661099A (zh) | 2014-05-27 | 2017-05-10 | 中央研究院 | 抗her2醣抗体及其用途 |
| WO2015184001A1 (en) | 2014-05-28 | 2015-12-03 | Academia Sinica | Anti-tnf-alpha glycoantibodies and uses thereof |
| US10883994B2 (en) | 2014-06-25 | 2021-01-05 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Identification of cancer stem cells markers and use of same for diagnosis and treatment |
| EP3189133A4 (en) * | 2014-09-04 | 2018-04-11 | Agency for Science, Technology and Research | A method to up-regulate cancer stem cell markers for the generation of antigen specific cytotoxic effector t cells |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗mfi2抗體及使用方法 |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| AU2016209056B2 (en) * | 2015-01-24 | 2021-01-28 | Academia Sinica | Cancer markers and methods of use thereof |
| RU2017129236A (ru) | 2015-01-26 | 2019-03-07 | Макродженикс, Инк. | Мультивалентные молекулы, содержащие dr5-связывающие домены |
| KR20160109356A (ko) | 2015-03-11 | 2016-09-21 | 이화여자대학교 산학협력단 | 자가 면역 질환 예방 또는 치료용 조성물 |
| KR102036029B1 (ko) | 2015-03-11 | 2019-10-24 | 이화여자대학교 산학협력단 | 골수 부전 예방 또는 치료용 조성물 |
| KR20160109358A (ko) | 2015-03-11 | 2016-09-21 | 이화여자대학교 산학협력단 | 면역 질환 예방 또는 치료용 조성물 |
| WO2016170938A1 (ja) * | 2015-04-20 | 2016-10-27 | 国立大学法人岡山大学 | がんの非ヒトモデル動物及びその作製方法、がん幹細胞及びその製造方法 |
| EP3208331A1 (en) * | 2016-02-17 | 2017-08-23 | PromoCell bioscience alive GmbH Biomedizinische Produkte | Chemically defined medium for the culture of cancer stem cell (csc) containing cell populations |
| GEP20227398B (en) | 2016-04-15 | 2022-07-25 | Macrogenics Inc | Novel b7-h3 binding molecules, antibody drug conjugates thereof and usage thereof |
| JP2019522960A (ja) | 2016-04-21 | 2019-08-22 | アッヴィ・ステムセントルクス・エル・エル・シー | 新規の抗bmpr1b抗体及び使用方法 |
| CA3034057A1 (en) | 2016-08-22 | 2018-03-01 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
| GB201700952D0 (en) * | 2017-01-19 | 2017-03-08 | Univ Cape Town | In vitro propagation of primary cancer cells |
| CN107904206A (zh) * | 2017-11-17 | 2018-04-13 | 张家港澳洋医院有限公司 | 一种脂多糖诱导肿瘤细胞生成肿瘤干细胞的用途和方法 |
| AU2019284405B2 (en) * | 2018-06-13 | 2025-08-21 | Genex Health Co.,Ltd | Colorectal cancer solid tumour primary cell and colorectal cancer ascitic fluid primary tumour cell culturing method, and matching reagent |
| KR102130493B1 (ko) | 2018-07-11 | 2020-07-06 | 이화여자대학교 산학협력단 | 건선 예방 또는 치료용 조성물 |
| KR102089476B1 (ko) | 2018-07-11 | 2020-03-16 | 이화여자대학교 산학협력단 | 피부 염증 질환 예방 또는 치료용 조성물 |
| CN109652377B (zh) * | 2019-01-15 | 2023-03-28 | 广州医科大学 | 一种肺癌干细胞的制备方法及应用 |
| JP2022546578A (ja) * | 2019-09-04 | 2022-11-04 | ブイセル セラピューティックス,インコーポレイテッド | 癌を処置するためのワクチンおよびストレスリプログラミングによるその作製方法 |
| KR20190120141A (ko) | 2019-10-16 | 2019-10-23 | 이화여자대학교 산학협력단 | 골수 부전 예방 또는 치료용 조성물 |
| CN113069547B (zh) * | 2021-04-16 | 2023-01-24 | 同济大学附属第一妇婴保健院 | Bap1作为肿瘤治疗靶点在制备预防或治疗肿瘤药物中的应用 |
| CN113444690A (zh) * | 2021-07-29 | 2021-09-28 | 大连大学 | 一种基于三维培养体系的肿瘤细胞耐照射模型的建立方法 |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US20050136066A1 (en) | 1996-06-12 | 2005-06-23 | Yajun Guo | Cellular vaccines and immunotherapeutics and methods for their preparation |
| US7348015B2 (en) * | 1998-01-14 | 2008-03-25 | Morphogenesis, Inc. | Antigen modified cancer cell vaccines for cancer therapy |
| US6416999B1 (en) * | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
| US6436704B1 (en) * | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
| US6984522B2 (en) * | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| US7148038B2 (en) | 2001-10-16 | 2006-12-12 | Raven Biotechnologies, Inc. | Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof |
| US20050260208A1 (en) | 2002-04-11 | 2005-11-24 | Altarex Medical Corp. | Binding agents and their use in targeting tumor cells |
| ATE488530T1 (de) | 2002-06-19 | 2010-12-15 | Raven Biotechnologies Inc | Internalisierende antikörper spezifisch für das raag10 zelloberflächenziel |
| MXPA06003028A (es) | 2003-09-18 | 2006-06-23 | Raven Biotechnologies Inc | Medios de cultivo de celulas. |
| GB0406215D0 (en) | 2004-03-19 | 2004-04-21 | Procure Therapeutics Ltd | Prostate stem cell |
| JP4824025B2 (ja) | 2004-06-07 | 2011-11-24 | マクロジェニックス ウエスト,インコーポレイテッド | トランスフェリンレセプター抗体 |
| ITRM20040438A1 (it) | 2004-09-15 | 2004-12-15 | Univ Palermo | Metodo per la purificazione e l'amplificazione di cellule staminali tumorali. |
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| US7687242B2 (en) | 2005-01-12 | 2010-03-30 | Raven Biotechnologies, Inc. | KID31 and antibodies that bind thereto |
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| CN101155830B (zh) | 2005-02-04 | 2014-06-18 | 雷文生物技术公司 | 结合epha2的抗体及其使用方法 |
| JP2009502156A (ja) * | 2005-07-26 | 2009-01-29 | プロキュア・セラピューティクス・リミテッド | 幹細胞マーカー |
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| CA2700573C (en) | 2006-09-26 | 2016-11-22 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| CA2675521C (en) | 2007-01-22 | 2016-04-26 | Raven Biotechnologies | Human cancer stem cells |
-
2008
- 2008-01-22 CA CA2675521A patent/CA2675521C/en not_active Expired - Fee Related
- 2008-01-22 AU AU2008207945A patent/AU2008207945A1/en not_active Abandoned
- 2008-01-22 KR KR1020097017268A patent/KR101523698B1/ko not_active Expired - Fee Related
- 2008-01-22 EP EP08728101A patent/EP2109668A4/en not_active Withdrawn
- 2008-01-22 US US12/018,126 patent/US8309354B2/en not_active Expired - Fee Related
- 2008-01-22 CN CN200880009078A patent/CN101855339A/zh active Pending
- 2008-01-22 WO PCT/US2008/051730 patent/WO2008091908A2/en not_active Ceased
- 2008-01-22 JP JP2009546581A patent/JP2010516259A/ja active Pending
-
2009
- 2009-07-13 IL IL199836A patent/IL199836A/en not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| Dalerba, P. et al., Annu. Rev. Med., 2007, vol.58, pp.267-284 (2006.9.26. 온라인 공개) * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2675521C (en) | 2016-04-26 |
| KR20100033471A (ko) | 2010-03-30 |
| AU2008207945A1 (en) | 2008-07-31 |
| US8309354B2 (en) | 2012-11-13 |
| US20080175870A1 (en) | 2008-07-24 |
| CN101855339A (zh) | 2010-10-06 |
| CA2675521A1 (en) | 2008-07-31 |
| IL199836A0 (en) | 2010-04-15 |
| WO2008091908A2 (en) | 2008-07-31 |
| EP2109668A2 (en) | 2009-10-21 |
| EP2109668A4 (en) | 2011-10-05 |
| WO2008091908A3 (en) | 2009-12-30 |
| JP2010516259A (ja) | 2010-05-20 |
| IL199836A (en) | 2014-02-27 |
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