KR101523698B1 - 사람 암 줄기세포 - Google Patents
사람 암 줄기세포 Download PDFInfo
- Publication number
- KR101523698B1 KR101523698B1 KR1020097017268A KR20097017268A KR101523698B1 KR 101523698 B1 KR101523698 B1 KR 101523698B1 KR 1020097017268 A KR1020097017268 A KR 1020097017268A KR 20097017268 A KR20097017268 A KR 20097017268A KR 101523698 B1 KR101523698 B1 KR 101523698B1
- Authority
- KR
- South Korea
- Prior art keywords
- stem cells
- cells
- cell
- cancer stem
- human
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88149707P | 2007-01-22 | 2007-01-22 | |
| US60/881,497 | 2007-01-22 | ||
| US90718007P | 2007-03-23 | 2007-03-23 | |
| US60/907,180 | 2007-03-23 | ||
| US92424707P | 2007-05-04 | 2007-05-04 | |
| US60/924,247 | 2007-05-04 | ||
| US95071407P | 2007-07-19 | 2007-07-19 | |
| US60/950,714 | 2007-07-19 | ||
| US97261307P | 2007-09-14 | 2007-09-14 | |
| US60/972,613 | 2007-09-14 | ||
| PCT/US2008/051730 WO2008091908A2 (en) | 2007-01-22 | 2008-01-22 | Human cancer stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20100033471A KR20100033471A (ko) | 2010-03-30 |
| KR101523698B1 true KR101523698B1 (ko) | 2015-05-29 |
Family
ID=39641454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097017268A Expired - Fee Related KR101523698B1 (ko) | 2007-01-22 | 2008-01-22 | 사람 암 줄기세포 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8309354B2 (enExample) |
| EP (1) | EP2109668A4 (enExample) |
| JP (1) | JP2010516259A (enExample) |
| KR (1) | KR101523698B1 (enExample) |
| CN (1) | CN101855339A (enExample) |
| AU (1) | AU2008207945A1 (enExample) |
| CA (1) | CA2675521C (enExample) |
| IL (1) | IL199836A (enExample) |
| WO (1) | WO2008091908A2 (enExample) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101855339A (zh) | 2007-01-22 | 2010-10-06 | 雷文生物技术公司 | 人类癌症干细胞 |
| EP2361988B1 (en) | 2008-10-27 | 2016-04-13 | Sapporo Medical University | Molecular marker for cancer stem cell |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| EP4190149A1 (en) | 2009-12-25 | 2023-06-07 | Chugai Seiyaku Kabushiki Kaisha | Method for searching and screening for target of anti-cancer agent using non-human animal model having nog established cancer cell line transplanted therein |
| US9150656B2 (en) | 2010-03-04 | 2015-10-06 | Macrogenics, Inc. | Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| WO2011129348A1 (ja) * | 2010-04-13 | 2011-10-20 | 株式会社Reiメディカル | 癌組織由来細胞塊または癌細胞凝集塊から得られる癌治療用組成物およびそれを用いた免疫療法剤の製造方法ならびに免疫療法効果評価方法 |
| ES2874953T3 (es) | 2010-07-23 | 2021-11-05 | Astellas Inst For Regenerative Medicine | Métodos para la detección de subpoblaciones raras de células y composiciones muy purificadas de células |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| US9778264B2 (en) | 2010-09-03 | 2017-10-03 | Abbvie Stemcentrx Llc | Identification and enrichment of cell subpopulations |
| CN103476429B (zh) * | 2010-09-03 | 2016-08-24 | 施特姆森特克斯股份有限公司 | 新型调节剂及使用方法 |
| WO2012031280A2 (en) | 2010-09-03 | 2012-03-08 | Stem Centrx, Inc. | Identification and enrichment of cell subpopulations |
| US11124773B2 (en) | 2010-10-06 | 2021-09-21 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell population and method for production thereof |
| US20140302034A1 (en) | 2010-12-08 | 2014-10-09 | Stem Centrx, Inc. | Novel modulators and methods of use |
| KR101182549B1 (ko) * | 2010-12-16 | 2012-09-12 | 엘지이노텍 주식회사 | 3차원 입체 카메라 모듈 |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| CA2830613A1 (en) * | 2011-03-24 | 2012-09-27 | The Rogosin Institute | Assay for screening compounds that selectively decrease the number of cancer stem cells |
| ME03440B (me) | 2011-05-21 | 2020-01-20 | Macrogenics Inc | Cd3-vezujući molekuli sposobni za vezivanje za humani i nehumani cd3 |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| EP2749641B1 (en) | 2011-09-07 | 2021-06-02 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell isolation |
| EP2772268B8 (en) | 2011-10-28 | 2020-01-08 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
| US10247731B2 (en) | 2012-02-22 | 2019-04-02 | Verik Bio, Inc. | System for immunotherapy targeting tumor propagation and progression |
| ES2741936T3 (es) | 2012-02-24 | 2020-02-12 | Abbvie Stemcentrx Llc | Anticuerpos anti-SEZ6 y procedimientos de uso |
| ES2812849T3 (es) | 2012-02-24 | 2021-03-18 | Abbvie Stemcentrx Llc | Anticuerpos anti-DLL3 y procedimientos de utilización de los mismos |
| JP6090735B2 (ja) * | 2012-03-02 | 2017-03-08 | 国立大学法人山口大学 | 消化器系がん幹細胞を培養するための無血清培地、及びそれを用いた消化器系がん幹細胞の増殖方法 |
| EP4361634A3 (en) | 2012-03-19 | 2024-06-05 | Stemline Therapeutics, Inc. | Methods for treating and monitoring the status of cancer |
| HUE056350T2 (hu) | 2012-05-16 | 2022-02-28 | Stemline Therapeutics Inc | Rákos õssejt célzott rák elleni vakcinák |
| WO2014130879A2 (en) | 2013-02-22 | 2014-08-28 | Stem Centrx, Inc. | Novel antibody conjugates and uses thereof |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| EP2968407A4 (en) * | 2013-03-13 | 2017-01-04 | Neostem Oncology, LLC | Individualized high purity colon carcinoma stem cells, methods and use of the same |
| EP3038462B1 (en) * | 2013-08-12 | 2023-03-15 | Minerva Biotechnologies Corporation | Method for enhancing tumor growth |
| PE20160674A1 (es) | 2013-08-28 | 2016-07-21 | Stemcentrx Inc | Metodos de conjugacion de anticuerpos especificos de sitio y composiciones |
| EP3338793A1 (en) | 2013-08-28 | 2018-06-27 | AbbVie Stemcentrx LLC | Novel sez6 modulators and methods of use |
| KR102298172B1 (ko) | 2013-09-06 | 2021-09-06 | 아카데미아 시니카 | 변화된 글리코실 그룹을 갖는 당지질을 사용한 인간 iNKT 세포 활성화 |
| RU2016122041A (ru) | 2013-11-06 | 2017-12-11 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Новые анти-клаудин антитела и способы их применения |
| JP2017500028A (ja) | 2013-12-12 | 2017-01-05 | アッヴィ・ステムセントルクス・エル・エル・シー | 新規の抗dpep3抗体および使用方法 |
| EA201691683A1 (ru) | 2014-02-21 | 2017-04-28 | ЭББВИ СТЕМСЕНТРКС ЭлЭлСи | Антитела против dll3 и конъюгаты антитело-лекарственное средство для применения при меланоме |
| US10005847B2 (en) | 2014-05-27 | 2018-06-26 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
| AU2015267052A1 (en) | 2014-05-27 | 2016-12-15 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| KR20240096599A (ko) | 2014-05-27 | 2024-06-26 | 아카데미아 시니카 | 항-cd20 글리코항체 및 이의 용도 |
| JP7063538B2 (ja) | 2014-05-28 | 2022-05-09 | アカデミア シニカ | 抗TNFα糖操作抗体群およびその使用 |
| ES2791199T3 (es) * | 2014-06-25 | 2020-11-03 | Tel Hashomer Medical Res Infrastructure & Services Ltd | Identificación de marcadores de células madre cancerosas y uso de los mismos para diagnóstico y tratamiento |
| WO2016036319A1 (en) * | 2014-09-04 | 2016-03-10 | Agency For Science, Technology And Research | A method to up-regulate cancer stem cell markers for the generation of antigen specific cytotoxic effector t cells |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗mfi2抗體及使用方法 |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| CN107430127B (zh) * | 2015-01-24 | 2020-08-28 | 中央研究院 | 癌症标记及其使用方法 |
| AU2015380455A1 (en) | 2015-01-26 | 2017-08-03 | Macrogenics, Inc. | Multivalent molecules comprising DR5-binding domains |
| KR20160109358A (ko) | 2015-03-11 | 2016-09-21 | 이화여자대학교 산학협력단 | 면역 질환 예방 또는 치료용 조성물 |
| KR20160109356A (ko) | 2015-03-11 | 2016-09-21 | 이화여자대학교 산학협력단 | 자가 면역 질환 예방 또는 치료용 조성물 |
| KR102036029B1 (ko) | 2015-03-11 | 2019-10-24 | 이화여자대학교 산학협력단 | 골수 부전 예방 또는 치료용 조성물 |
| JP6161828B2 (ja) * | 2015-04-20 | 2017-07-12 | 国立大学法人 岡山大学 | がんの非ヒトモデル動物及びその作製方法、がん幹細胞及びその製造方法 |
| EP3208331A1 (en) * | 2016-02-17 | 2017-08-23 | PromoCell bioscience alive GmbH Biomedizinische Produkte | Chemically defined medium for the culture of cancer stem cell (csc) containing cell populations |
| MY198114A (en) | 2016-04-15 | 2023-08-04 | Macrogenics Inc | Novel b7-h3-binding molecules, antibody drug conjugates thereof and methods of use thereof |
| JP2019522960A (ja) | 2016-04-21 | 2019-08-22 | アッヴィ・ステムセントルクス・エル・エル・シー | 新規の抗bmpr1b抗体及び使用方法 |
| AU2017316663B2 (en) | 2016-08-22 | 2024-02-22 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
| GB201700952D0 (en) * | 2017-01-19 | 2017-03-08 | Univ Cape Town | In vitro propagation of primary cancer cells |
| CN107904206A (zh) * | 2017-11-17 | 2018-04-13 | 张家港澳洋医院有限公司 | 一种脂多糖诱导肿瘤细胞生成肿瘤干细胞的用途和方法 |
| EP3896154A4 (en) * | 2018-06-13 | 2022-03-09 | Genex Health Co.,Ltd | PRIMARY CELL OF SOLID TUMOR IN COLORECTAL CANCER AND METHODS FOR CULTIVATION OF PRIMARY TUMOR CELL FROM ASCITES IN COLORECTAL CANCER AND RELEVANT REAGENT |
| KR102089476B1 (ko) | 2018-07-11 | 2020-03-16 | 이화여자대학교 산학협력단 | 피부 염증 질환 예방 또는 치료용 조성물 |
| KR102130493B1 (ko) | 2018-07-11 | 2020-07-06 | 이화여자대학교 산학협력단 | 건선 예방 또는 치료용 조성물 |
| CN109652377B (zh) * | 2019-01-15 | 2023-03-28 | 广州医科大学 | 一种肺癌干细胞的制备方法及应用 |
| JP2022546578A (ja) * | 2019-09-04 | 2022-11-04 | ブイセル セラピューティックス,インコーポレイテッド | 癌を処置するためのワクチンおよびストレスリプログラミングによるその作製方法 |
| KR20190120141A (ko) | 2019-10-16 | 2019-10-23 | 이화여자대학교 산학협력단 | 골수 부전 예방 또는 치료용 조성물 |
| CN113069547B (zh) * | 2021-04-16 | 2023-01-24 | 同济大学附属第一妇婴保健院 | Bap1作为肿瘤治疗靶点在制备预防或治疗肿瘤药物中的应用 |
| CN113444690A (zh) * | 2021-07-29 | 2021-09-28 | 大连大学 | 一种基于三维培养体系的肿瘤细胞耐照射模型的建立方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US20050136066A1 (en) | 1996-06-12 | 2005-06-23 | Yajun Guo | Cellular vaccines and immunotherapeutics and methods for their preparation |
| US7348015B2 (en) | 1998-01-14 | 2008-03-25 | Morphogenesis, Inc. | Antigen modified cancer cell vaccines for cancer therapy |
| US6416999B1 (en) | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
| US6436704B1 (en) | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
| US6984522B2 (en) * | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| ATE524196T1 (de) | 2001-10-16 | 2011-09-15 | Macrogenics West Inc | An das krebsassoziierte antigen cd46 bindende antikörper und verwendungsverfahren dafür |
| JP2005522483A (ja) | 2002-04-11 | 2005-07-28 | アルタレックス メディカル コーポレーション | 結合剤及び腫瘍細胞をターゲティングする際のそれらの使用 |
| EP1565489B1 (en) | 2002-06-19 | 2010-11-17 | Raven Biotechnologies, Inc. | Internalizing antibodies specific for the RAAG10 cell surface target |
| KR20060076781A (ko) | 2003-09-18 | 2006-07-04 | 레이븐 바이오테크놀로지스, 인코퍼레이티드 | 세포 배양 배지 |
| GB0406215D0 (en) | 2004-03-19 | 2004-04-21 | Procure Therapeutics Ltd | Prostate stem cell |
| US7572895B2 (en) | 2004-06-07 | 2009-08-11 | Raven Biotechnologies, Inc. | Transferrin receptor antibodies |
| ITRM20040438A1 (it) | 2004-09-15 | 2004-12-15 | Univ Palermo | Metodo per la purificazione e l'amplificazione di cellule staminali tumorali. |
| CA2629330C (en) | 2004-11-12 | 2018-05-22 | Cambridge University Technical Services Ltd. | Methods and means related to cancer stem cells |
| CA2593786A1 (en) | 2005-01-12 | 2006-07-20 | Raven Biotechnologies, Inc. | Kid31 and antibodies that bind thereto |
| JP5328155B2 (ja) | 2005-02-02 | 2013-10-30 | マクロジェニックス ウエスト, インコーポレイテッド | Adam−9モジュレータ |
| US20060171952A1 (en) | 2005-02-02 | 2006-08-03 | Mather Jennie P | JAM-3 and antibodies that bind thereto |
| JP5328156B2 (ja) | 2005-02-03 | 2013-10-30 | マクロジェニックス ウエスト, インコーポレイテッド | オンコスタチンmレセプターに対する抗体 |
| KR101363252B1 (ko) | 2005-02-04 | 2014-02-13 | 레이븐 바이오테크놀로지스, 인코퍼레이티드 | Epha2에 결합하는 항체 및 그것의 사용방법 |
| CA2657886A1 (en) * | 2005-07-26 | 2007-02-01 | Procure Therapeutics Limited | Stem cell markers |
| US20070123448A1 (en) | 2005-11-23 | 2007-05-31 | The Hospital For Sick Children | Novel chemical entities affecting neuroblastoma tumor-initiating cells |
| CA2700573C (en) * | 2006-09-26 | 2016-11-22 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| CN101855339A (zh) | 2007-01-22 | 2010-10-06 | 雷文生物技术公司 | 人类癌症干细胞 |
-
2008
- 2008-01-22 CN CN200880009078A patent/CN101855339A/zh active Pending
- 2008-01-22 KR KR1020097017268A patent/KR101523698B1/ko not_active Expired - Fee Related
- 2008-01-22 JP JP2009546581A patent/JP2010516259A/ja active Pending
- 2008-01-22 CA CA2675521A patent/CA2675521C/en not_active Expired - Fee Related
- 2008-01-22 AU AU2008207945A patent/AU2008207945A1/en not_active Abandoned
- 2008-01-22 EP EP08728101A patent/EP2109668A4/en not_active Withdrawn
- 2008-01-22 US US12/018,126 patent/US8309354B2/en not_active Expired - Fee Related
- 2008-01-22 WO PCT/US2008/051730 patent/WO2008091908A2/en not_active Ceased
-
2009
- 2009-07-13 IL IL199836A patent/IL199836A/en not_active IP Right Cessation
Non-Patent Citations (1)
| Title |
|---|
| Dalerba, P. et al., Annu. Rev. Med., 2007, vol.58, pp.267-284 (2006.9.26. 온라인 공개) * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN101855339A (zh) | 2010-10-06 |
| WO2008091908A3 (en) | 2009-12-30 |
| EP2109668A2 (en) | 2009-10-21 |
| KR20100033471A (ko) | 2010-03-30 |
| IL199836A (en) | 2014-02-27 |
| EP2109668A4 (en) | 2011-10-05 |
| JP2010516259A (ja) | 2010-05-20 |
| US20080175870A1 (en) | 2008-07-24 |
| WO2008091908A2 (en) | 2008-07-31 |
| AU2008207945A1 (en) | 2008-07-31 |
| CA2675521A1 (en) | 2008-07-31 |
| US8309354B2 (en) | 2012-11-13 |
| CA2675521C (en) | 2016-04-26 |
| IL199836A0 (en) | 2010-04-15 |
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