IL199836A - Human stem cells are isolated and used - Google Patents
Human stem cells are isolated and usedInfo
- Publication number
- IL199836A IL199836A IL199836A IL19983609A IL199836A IL 199836 A IL199836 A IL 199836A IL 199836 A IL199836 A IL 199836A IL 19983609 A IL19983609 A IL 19983609A IL 199836 A IL199836 A IL 199836A
- Authority
- IL
- Israel
- Prior art keywords
- stem cells
- cancer stem
- human cancer
- isolated human
- isolated
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 210000000130 stem cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0693—Tumour cells; Cancer cells
- C12N5/0695—Stem cells; Progenitor cells; Precursor cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Developmental Biology & Embryology (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88149707P | 2007-01-22 | 2007-01-22 | |
| US90718007P | 2007-03-23 | 2007-03-23 | |
| US92424707P | 2007-05-04 | 2007-05-04 | |
| US95071407P | 2007-07-19 | 2007-07-19 | |
| US97261307P | 2007-09-14 | 2007-09-14 | |
| PCT/US2008/051730 WO2008091908A2 (en) | 2007-01-22 | 2008-01-22 | Human cancer stem cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL199836A0 IL199836A0 (en) | 2010-04-15 |
| IL199836A true IL199836A (en) | 2014-02-27 |
Family
ID=39641454
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL199836A IL199836A (en) | 2007-01-22 | 2009-07-13 | Human stem cells are isolated and used |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US8309354B2 (enExample) |
| EP (1) | EP2109668A4 (enExample) |
| JP (1) | JP2010516259A (enExample) |
| KR (1) | KR101523698B1 (enExample) |
| CN (1) | CN101855339A (enExample) |
| AU (1) | AU2008207945A1 (enExample) |
| CA (1) | CA2675521C (enExample) |
| IL (1) | IL199836A (enExample) |
| WO (1) | WO2008091908A2 (enExample) |
Families Citing this family (66)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2008207945A1 (en) | 2007-01-22 | 2008-07-31 | Macrogenics West, Inc. | Human cancer stem cells |
| EP2361988B1 (en) | 2008-10-27 | 2016-04-13 | Sapporo Medical University | Molecular marker for cancer stem cell |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| EP2517555A4 (en) | 2009-12-25 | 2014-09-24 | Chugai Pharmaceutical Co Ltd | SEARCHING AND SCREENING METHOD FOR A TARGET MOLECULE OF A CANCER WITH A NON-MENTAL ANIMAL MODEL WITH A NO-CANCER LINE OF TRANSPLANTED LINE |
| KR101828570B1 (ko) | 2010-03-04 | 2018-02-13 | 마크로제닉스, 인크. | B7―h3에 반응성인 항체, 면역학적으로 활성인 이들의 단편 및 이들의 사용법 |
| PH12012501751A1 (en) | 2010-03-04 | 2012-11-12 | Macrogenics Inc | Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof |
| WO2011129348A1 (ja) * | 2010-04-13 | 2011-10-20 | 株式会社Reiメディカル | 癌組織由来細胞塊または癌細胞凝集塊から得られる癌治療用組成物およびそれを用いた免疫療法剤の製造方法ならびに免疫療法効果評価方法 |
| JP6184865B2 (ja) | 2010-07-23 | 2017-08-23 | アステラス インスティテュート フォー リジェネレイティブ メディシン | 細胞の稀少なサブ集団を検出するための方法及び細胞の高度に精製された組成物 |
| WO2012019061A2 (en) | 2010-08-05 | 2012-02-09 | Stem Centrx, Inc. | Novel effectors and methods of use |
| US9778264B2 (en) | 2010-09-03 | 2017-10-03 | Abbvie Stemcentrx Llc | Identification and enrichment of cell subpopulations |
| NZ608814A (en) | 2010-09-03 | 2015-06-26 | Stem Centrx Inc | Novel modulators and methods of use |
| EP2611463A2 (en) | 2010-09-03 | 2013-07-10 | Stem Centrx, Inc. | Identification and enrichment of cell subpopulations |
| CN103328626B (zh) * | 2010-10-06 | 2017-02-08 | 中外制药株式会社 | 癌干细胞群及其制备方法 |
| PE20171143A1 (es) | 2010-12-08 | 2017-08-10 | Stem Centrx Inc | Nuevos moduladores y metodos para su uso |
| KR101182549B1 (ko) * | 2010-12-16 | 2012-09-12 | 엘지이노텍 주식회사 | 3차원 입체 카메라 모듈 |
| SA112330278B1 (ar) | 2011-02-18 | 2015-10-09 | ستيم سينتركس، انك. | مواد ضابطة جديدة وطرق للاستخدام |
| US20140364402A1 (en) * | 2011-03-24 | 2014-12-11 | The Rogosin Institute | Assay for screening compounds that selectively decrease the number of cancer stem cells |
| SI2714733T1 (sl) | 2011-05-21 | 2019-06-28 | Macrogenics, Inc. | CD3-vezavne molekule sposobne vezave na humani ali ne-humani CD3 |
| US20130058947A1 (en) | 2011-09-02 | 2013-03-07 | Stem Centrx, Inc | Novel Modulators and Methods of Use |
| JP6077997B2 (ja) * | 2011-09-07 | 2017-02-08 | 中外製薬株式会社 | 癌幹細胞の分離 |
| EP3603671A3 (en) | 2011-10-28 | 2020-07-29 | Chugai Seiyaku Kabushiki Kaisha | Cancer stem cell-specific molecule |
| US10247731B2 (en) | 2012-02-22 | 2019-04-02 | Verik Bio, Inc. | System for immunotherapy targeting tumor propagation and progression |
| WO2013126810A1 (en) | 2012-02-24 | 2013-08-29 | Stem Centrx, Inc. | Anti sez6 antibodies and methods of use |
| RS56443B1 (sr) | 2012-02-24 | 2018-01-31 | Abbvie Stemcentrx Llc | Ddl3 modulatori i postupci primene |
| JP6090735B2 (ja) * | 2012-03-02 | 2017-03-08 | 国立大学法人山口大学 | 消化器系がん幹細胞を培養するための無血清培地、及びそれを用いた消化器系がん幹細胞の増殖方法 |
| ES2887580T3 (es) * | 2012-03-19 | 2021-12-23 | Stemline Therapeutics Inc | Métodos para el tratamiento y seguimiento del estado del cáncer |
| EP2849772A4 (en) | 2012-05-16 | 2016-03-02 | Stemline Therapeutics Inc | TUMOR VACCINES TREATED AGAINST CANCER STEM CELLS |
| ME03394B (me) | 2013-02-22 | 2020-01-20 | Medimmune Ltd | Antidllз-antitelo-pbd konjugati i nihovа upotreba |
| US9487587B2 (en) | 2013-03-05 | 2016-11-08 | Macrogenics, Inc. | Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof |
| AU2014248711A1 (en) * | 2013-03-13 | 2015-09-10 | Neostem Oncology, Llc | Individualized high purity colon carcinoma stem cells, methods and use of the same |
| CN105764334B (zh) * | 2013-08-12 | 2020-07-28 | 密内瓦生物技术公司 | 加强肿瘤生长的方法 |
| CN105848671B (zh) | 2013-08-28 | 2019-12-13 | 艾伯维施特姆森特克斯有限责任公司 | 位点特异性抗体缀合方法和组合物 |
| US9993566B2 (en) | 2013-08-28 | 2018-06-12 | Abbvie Stemcentrx Llc | SEZ6 modulators and methods of use |
| WO2015035337A1 (en) | 2013-09-06 | 2015-03-12 | Academia Sinica | HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS WITH ALTERED GLYCOSYL GROUPS |
| MX2016005763A (es) | 2013-11-06 | 2016-08-19 | Stemcentrx Inc | Anticuerpos anti-claudina novedosos y metodos de uso. |
| WO2015089449A2 (en) | 2013-12-12 | 2015-06-18 | Stem Centrx, Inc. | Novel anti-dpep3 antibodies and methods of use |
| MX2016010677A (es) | 2014-02-21 | 2017-04-10 | Abbvie Stemcentrx Llc | Conjugados de anticuerpos anti-drosophila similar a delta 3 (anti-dll3) y medicamentos para usarse en el tratamiento contra melanoma. |
| KR20220151036A (ko) | 2014-05-27 | 2022-11-11 | 아카데미아 시니카 | 항-cd20 글리코항체 및 이의 용도 |
| CA2950440A1 (en) | 2014-05-27 | 2015-12-03 | Academia Sinica | Anti-her2 glycoantibodies and uses thereof |
| TWI654202B (zh) | 2014-05-27 | 2019-03-21 | 中央研究院 | 增進抗體功效之通用糖型之組合物及方法 |
| TWI732738B (zh) | 2014-05-28 | 2021-07-11 | 中央研究院 | 抗TNF-α醣抗體及其用途 |
| CN106537148B (zh) * | 2014-06-25 | 2019-10-11 | 泰尔哈绍梅尔医学研究基础设施和服务有限公司 | 癌症干细胞的鉴定及其用于诊断和治疗的用途 |
| EP3189133A4 (en) * | 2014-09-04 | 2018-04-11 | Agency for Science, Technology and Research | A method to up-regulate cancer stem cell markers for the generation of antigen specific cytotoxic effector t cells |
| TW201617368A (zh) | 2014-09-05 | 2016-05-16 | 史坦森特瑞斯公司 | 新穎抗mfi2抗體及使用方法 |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| CN112430268A (zh) * | 2015-01-24 | 2021-03-02 | 中央研究院 | 癌症标记及其使用方法 |
| HK1247215A1 (zh) | 2015-01-26 | 2018-09-21 | Macrogenics, Inc. | 包含dr5-结合结构域的多价分子 |
| KR20160109358A (ko) | 2015-03-11 | 2016-09-21 | 이화여자대학교 산학협력단 | 면역 질환 예방 또는 치료용 조성물 |
| KR102036029B1 (ko) | 2015-03-11 | 2019-10-24 | 이화여자대학교 산학협력단 | 골수 부전 예방 또는 치료용 조성물 |
| KR20160109356A (ko) | 2015-03-11 | 2016-09-21 | 이화여자대학교 산학협력단 | 자가 면역 질환 예방 또는 치료용 조성물 |
| JP6161828B2 (ja) * | 2015-04-20 | 2017-07-12 | 国立大学法人 岡山大学 | がんの非ヒトモデル動物及びその作製方法、がん幹細胞及びその製造方法 |
| EP3208331A1 (en) * | 2016-02-17 | 2017-08-23 | PromoCell bioscience alive GmbH Biomedizinische Produkte | Chemically defined medium for the culture of cancer stem cell (csc) containing cell populations |
| CR20180484A (es) | 2016-04-15 | 2019-03-05 | Macrogenics Inc | Moléculas de unón b7-h3 novedosas, conjugados anticuerpos-fármaco de los mismos y métodos de uso de los mismos |
| AU2017254674A1 (en) | 2016-04-21 | 2018-11-01 | Abbvie Stemcentrx Llc | Novel anti-BMPR1B antibodies and methods of use |
| WO2018039274A1 (en) | 2016-08-22 | 2018-03-01 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
| GB201700952D0 (en) * | 2017-01-19 | 2017-03-08 | Univ Cape Town | In vitro propagation of primary cancer cells |
| CN107904206A (zh) * | 2017-11-17 | 2018-04-13 | 张家港澳洋医院有限公司 | 一种脂多糖诱导肿瘤细胞生成肿瘤干细胞的用途和方法 |
| US12378529B2 (en) * | 2018-06-13 | 2025-08-05 | Genex Health Co., Ltd | Method for culturing colorectal cancer solid tumor primary cells and colorectal cancer ascites primary tumor cells and supporting reagents |
| KR102130493B1 (ko) | 2018-07-11 | 2020-07-06 | 이화여자대학교 산학협력단 | 건선 예방 또는 치료용 조성물 |
| KR102089476B1 (ko) | 2018-07-11 | 2020-03-16 | 이화여자대학교 산학협력단 | 피부 염증 질환 예방 또는 치료용 조성물 |
| CN109652377B (zh) * | 2019-01-15 | 2023-03-28 | 广州医科大学 | 一种肺癌干细胞的制备方法及应用 |
| CA3150099A1 (en) * | 2019-09-04 | 2021-03-11 | Charles A. Vacanti | VACCINE FOR THE TREATMENT OF CANCER AND METHOD OF MANUFACTURE BY REPROGRAMMING BY STRESS |
| KR20190120141A (ko) | 2019-10-16 | 2019-10-23 | 이화여자대학교 산학협력단 | 골수 부전 예방 또는 치료용 조성물 |
| CN113069547B (zh) * | 2021-04-16 | 2023-01-24 | 同济大学附属第一妇婴保健院 | Bap1作为肿瘤治疗靶点在制备预防或治疗肿瘤药物中的应用 |
| CN113444690A (zh) * | 2021-07-29 | 2021-09-28 | 大连大学 | 一种基于三维培养体系的肿瘤细胞耐照射模型的建立方法 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US20050136066A1 (en) | 1996-06-12 | 2005-06-23 | Yajun Guo | Cellular vaccines and immunotherapeutics and methods for their preparation |
| US7348015B2 (en) | 1998-01-14 | 2008-03-25 | Morphogenesis, Inc. | Antigen modified cancer cell vaccines for cancer therapy |
| US6416999B1 (en) | 2000-04-07 | 2002-07-09 | Raven Biotechnologies, Inc. | Human Müllerian duct-derived epithelial cells and methods of isolation and uses thereof |
| US6436704B1 (en) | 2000-04-10 | 2002-08-20 | Raven Biotechnologies, Inc. | Human pancreatic epithelial progenitor cells and methods of isolation and use thereof |
| US6984522B2 (en) * | 2000-08-03 | 2006-01-10 | Regents Of The University Of Michigan | Isolation and use of solid tumor stem cells |
| US7148038B2 (en) | 2001-10-16 | 2006-12-12 | Raven Biotechnologies, Inc. | Antibodies that bind to cancer-associated antigen CD46 and methods of use thereof |
| CA2481796A1 (en) | 2002-04-11 | 2003-10-23 | Altarex Medical Corporation | Binding agents and their use in targeting tumor cells |
| ATE488530T1 (de) | 2002-06-19 | 2010-12-15 | Raven Biotechnologies Inc | Internalisierende antikörper spezifisch für das raag10 zelloberflächenziel |
| CA2537462A1 (en) | 2003-09-18 | 2005-03-31 | Raven Biotechnologies, Inc. | Cell culture media comprising fructose as the primary energy source |
| GB0406215D0 (en) | 2004-03-19 | 2004-04-21 | Procure Therapeutics Ltd | Prostate stem cell |
| US7572895B2 (en) | 2004-06-07 | 2009-08-11 | Raven Biotechnologies, Inc. | Transferrin receptor antibodies |
| ITRM20040438A1 (it) | 2004-09-15 | 2004-12-15 | Univ Palermo | Metodo per la purificazione e l'amplificazione di cellule staminali tumorali. |
| CA2998412C (en) | 2004-11-12 | 2024-01-02 | Cambridge University Technical Services Ltd. | Methods and means related to cancer stem cells |
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| JP5328155B2 (ja) | 2005-02-02 | 2013-10-30 | マクロジェニックス ウエスト, インコーポレイテッド | Adam−9モジュレータ |
| US20060171952A1 (en) | 2005-02-02 | 2006-08-03 | Mather Jennie P | JAM-3 and antibodies that bind thereto |
| US7572896B2 (en) | 2005-02-03 | 2009-08-11 | Raven Biotechnologies, Inc. | Antibodies to oncostatin M receptor |
| BRPI0607450A2 (pt) | 2005-02-04 | 2009-09-01 | Raven Biotechnologies Inc | anticorpos que se ligam a epha2 e métodos para sua utilização |
| US20090012024A1 (en) | 2005-07-26 | 2009-01-08 | Procure Therapeutics Limited | Stem Cell Markers |
| US20070123448A1 (en) | 2005-11-23 | 2007-05-31 | The Hospital For Sick Children | Novel chemical entities affecting neuroblastoma tumor-initiating cells |
| CA2700573C (en) | 2006-09-26 | 2016-11-22 | Cedars-Sinai Medical Center | Cancer stem cell antigen vaccines and methods |
| AU2008207945A1 (en) | 2007-01-22 | 2008-07-31 | Macrogenics West, Inc. | Human cancer stem cells |
-
2008
- 2008-01-22 AU AU2008207945A patent/AU2008207945A1/en not_active Abandoned
- 2008-01-22 CA CA2675521A patent/CA2675521C/en not_active Expired - Fee Related
- 2008-01-22 WO PCT/US2008/051730 patent/WO2008091908A2/en not_active Ceased
- 2008-01-22 EP EP08728101A patent/EP2109668A4/en not_active Withdrawn
- 2008-01-22 KR KR1020097017268A patent/KR101523698B1/ko not_active Expired - Fee Related
- 2008-01-22 CN CN200880009078A patent/CN101855339A/zh active Pending
- 2008-01-22 JP JP2009546581A patent/JP2010516259A/ja active Pending
- 2008-01-22 US US12/018,126 patent/US8309354B2/en not_active Expired - Fee Related
-
2009
- 2009-07-13 IL IL199836A patent/IL199836A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR20100033471A (ko) | 2010-03-30 |
| JP2010516259A (ja) | 2010-05-20 |
| EP2109668A2 (en) | 2009-10-21 |
| CA2675521C (en) | 2016-04-26 |
| WO2008091908A3 (en) | 2009-12-30 |
| WO2008091908A2 (en) | 2008-07-31 |
| US8309354B2 (en) | 2012-11-13 |
| CA2675521A1 (en) | 2008-07-31 |
| US20080175870A1 (en) | 2008-07-24 |
| CN101855339A (zh) | 2010-10-06 |
| IL199836A0 (en) | 2010-04-15 |
| AU2008207945A1 (en) | 2008-07-31 |
| KR101523698B1 (ko) | 2015-05-29 |
| EP2109668A4 (en) | 2011-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |