KR101168189B1 - 불쾌미를 개선한 피복 제제의 제조 방법 - Google Patents

불쾌미를 개선한 피복 제제의 제조 방법 Download PDF

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KR101168189B1
KR101168189B1 KR1020067007456A KR20067007456A KR101168189B1 KR 101168189 B1 KR101168189 B1 KR 101168189B1 KR 1020067007456 A KR1020067007456 A KR 1020067007456A KR 20067007456 A KR20067007456 A KR 20067007456A KR 101168189 B1 KR101168189 B1 KR 101168189B1
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South Korea
Prior art keywords
coating formulation
waxy substance
coating
weight
binder
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KR1020067007456A
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English (en)
Korean (ko)
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KR20060095564A (ko
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히로시 다나카
츠요시 혼다
히데아키 기타지마
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시오노기세이야쿠가부시키가이샤
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1020067007456A 2003-10-29 2004-10-27 불쾌미를 개선한 피복 제제의 제조 방법 KR101168189B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003368891 2003-10-29
JPJP-P-2003-00368891 2003-10-29
PCT/JP2004/015884 WO2005039538A1 (ja) 2003-10-29 2004-10-27 不快味を改善した被覆製剤の製造方法

Publications (2)

Publication Number Publication Date
KR20060095564A KR20060095564A (ko) 2006-08-31
KR101168189B1 true KR101168189B1 (ko) 2012-07-25

Family

ID=34510363

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067007456A KR101168189B1 (ko) 2003-10-29 2004-10-27 불쾌미를 개선한 피복 제제의 제조 방법

Country Status (5)

Country Link
JP (1) JP3981134B2 (zh)
KR (1) KR101168189B1 (zh)
CN (1) CN100528233C (zh)
TW (1) TWI367767B (zh)
WO (1) WO2005039538A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2784881C (en) * 2005-02-25 2016-02-09 Takeda Pharmaceutical Company Limited Method for producing granules
JP2011153075A (ja) * 2008-04-04 2011-08-11 Shionogi & Co Ltd 水懸濁性を向上させた細粒剤
JP4336380B1 (ja) * 2008-11-06 2009-09-30 塩野義製薬株式会社 水懸濁性を向上させた細粒剤
JP6196730B2 (ja) * 2014-03-31 2017-09-13 富山化学工業株式会社 セファロスポリンエステルを含む粒状固形製剤およびその製造方法
CN104586854B (zh) * 2014-12-24 2017-08-15 石家庄四药有限公司 头孢呋辛酯药物组合物及其制备方法
JP6809675B2 (ja) * 2016-10-14 2021-01-06 ハウスウェルネスフーズ株式会社 植物抽出物を含有する口腔内即溶性顆粒の製造方法
SG10202109130WA (en) * 2017-02-21 2021-09-29 Ea Pharma Co Ltd Granular preparation
CN114340601A (zh) * 2019-09-25 2022-04-12 耐贝医药株式会社 掩盖了令人不快的味道的颗粒剂及其制造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58214333A (ja) * 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd 粒状物
JPH0647531B2 (ja) * 1986-02-06 1994-06-22 第一製薬株式会社 徐放性粒状物の製造法
JPS6327423A (ja) * 1986-07-17 1988-02-05 Shionogi & Co Ltd 固形製剤のコ−テイング法
JPH07100665B2 (ja) * 1987-12-23 1995-11-01 信越化学工業株式会社 被覆薬剤の製造方法
JPH01287021A (ja) * 1988-05-13 1989-11-17 Shin Etsu Chem Co Ltd ワックス複覆薬剤の製造方法
JP3130058B2 (ja) * 1991-02-15 2001-01-31 第一製薬株式会社 マスクされた粒状物
JP2960790B2 (ja) * 1991-03-25 1999-10-12 塩野義製薬株式会社 経口投与用セファロスポリン水和物結晶
JP3006901B2 (ja) * 1991-03-29 2000-02-07 塩野義製薬株式会社 被覆製剤
JP2987813B2 (ja) * 1993-07-12 1999-12-06 住友製薬株式会社 ワックス被覆製剤およびその製法
JP3776941B2 (ja) * 1993-12-24 2006-05-24 塩野義製薬株式会社 味覚の改善された顆粒剤及びその製造方法
ATE283038T1 (de) * 1995-07-21 2004-12-15 Daiichi Seiyaku Co Verfahren zu herstellung einer granulären zubereitung
EP0958813B1 (en) * 1996-09-13 2005-04-06 Shionogi & Co., Ltd. Sustained-release preparation utilizing thermal change and process for the production thereof
JP3466921B2 (ja) * 1998-06-03 2003-11-17 大塚製薬株式会社 味マスキング医薬製剤
JP2001270821A (ja) * 2000-03-23 2001-10-02 Eisai Co Ltd 服用感が優れた散剤
JP2001302497A (ja) * 2000-04-21 2001-10-31 Eisai Co Ltd 混合性に優れた散剤
JP4300821B2 (ja) * 2002-03-05 2009-07-22 住友化学株式会社 アミノ酸化合物
JP3797605B2 (ja) * 2002-03-20 2006-07-19 旭化成ファーマ株式会社 粒状被覆製剤の製造方法

Also Published As

Publication number Publication date
JP3981134B2 (ja) 2007-09-26
TW200515923A (en) 2005-05-16
WO2005039538A1 (ja) 2005-05-06
TWI367767B (en) 2012-07-11
KR20060095564A (ko) 2006-08-31
JPWO2005039538A1 (ja) 2007-11-22
CN1874759A (zh) 2006-12-06
CN100528233C (zh) 2009-08-19

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