TWI367767B - Method for producing a coat formulation improved discomfort taste - Google Patents

Method for producing a coat formulation improved discomfort taste

Info

Publication number
TWI367767B
TWI367767B TW093132662A TW93132662A TWI367767B TW I367767 B TWI367767 B TW I367767B TW 093132662 A TW093132662 A TW 093132662A TW 93132662 A TW93132662 A TW 93132662A TW I367767 B TWI367767 B TW I367767B
Authority
TW
Taiwan
Prior art keywords
producing
coat formulation
formulation improved
taste
improved discomfort
Prior art date
Application number
TW093132662A
Other languages
Chinese (zh)
Other versions
TW200515923A (en
Inventor
Hiroshi Tanaka
Tsuyoshi Honda
Hideaki Kitajima
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of TW200515923A publication Critical patent/TW200515923A/en
Application granted granted Critical
Publication of TWI367767B publication Critical patent/TWI367767B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
TW093132662A 2003-10-29 2004-10-28 Method for producing a coat formulation improved discomfort taste TWI367767B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2003368891 2003-10-29

Publications (2)

Publication Number Publication Date
TW200515923A TW200515923A (en) 2005-05-16
TWI367767B true TWI367767B (en) 2012-07-11

Family

ID=34510363

Family Applications (1)

Application Number Title Priority Date Filing Date
TW093132662A TWI367767B (en) 2003-10-29 2004-10-28 Method for producing a coat formulation improved discomfort taste

Country Status (5)

Country Link
JP (1) JP3981134B2 (en)
KR (1) KR101168189B1 (en)
CN (1) CN100528233C (en)
TW (1) TWI367767B (en)
WO (1) WO2005039538A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2275088B2 (en) * 2005-02-25 2018-09-26 Takeda Pharmaceutical Company Limited Method for producing granules
JP2011153075A (en) * 2008-04-04 2011-08-11 Shionogi & Co Ltd Fine granule having improved suspension performance in water
JP4336380B1 (en) * 2008-11-06 2009-09-30 塩野義製薬株式会社 Fine granules with improved water suspension
WO2015152190A1 (en) * 2014-03-31 2015-10-08 富山化学工業株式会社 Granular solid formulation containing cephalosporin ester, and method for producing same
CN104586854B (en) * 2014-12-24 2017-08-15 石家庄四药有限公司 Cefuroxime axetil pharmaceutical composition and preparation method thereof
JP6809675B2 (en) * 2016-10-14 2021-01-06 ハウスウェルネスフーズ株式会社 Method for Producing Immediate Oral Granules Containing Plant Extract
SG10202109130WA (en) * 2017-02-21 2021-09-29 Ea Pharma Co Ltd Granular preparation
CN114340601A (en) * 2019-09-25 2022-04-12 耐贝医药株式会社 Granules with masked unpleasant taste and process for producing the same

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58214333A (en) * 1982-06-04 1983-12-13 Dai Ichi Seiyaku Co Ltd Granular substance
JPH0647531B2 (en) * 1986-02-06 1994-06-22 第一製薬株式会社 Method for manufacturing sustained-release granules
JPS6327423A (en) * 1986-07-17 1988-02-05 Shionogi & Co Ltd Coating method for solid pharmaceutical
JPH07100665B2 (en) * 1987-12-23 1995-11-01 信越化学工業株式会社 Method for producing coating agent
JPH01287021A (en) * 1988-05-13 1989-11-17 Shin Etsu Chem Co Ltd Preparation of wax-coated drug preparation
JP3130058B2 (en) * 1991-02-15 2001-01-31 第一製薬株式会社 Masked granules
JP2960790B2 (en) * 1991-03-25 1999-10-12 塩野義製薬株式会社 Cephalosporin hydrate crystals for oral administration
JP3006901B2 (en) * 1991-03-29 2000-02-07 塩野義製薬株式会社 Coated preparation
JP2987813B2 (en) * 1993-07-12 1999-12-06 住友製薬株式会社 Wax-coated preparation and its production method
JP3776941B2 (en) * 1993-12-24 2006-05-24 塩野義製薬株式会社 Granules with improved taste and method for producing the same
US6217910B1 (en) * 1995-07-21 2001-04-17 Daiichi Pharmaceutical Co., Ltd. Granular preparation and producing process thereof
DE69732983T2 (en) * 1996-09-13 2006-02-16 Shionogi & Co., Ltd. PREPARATION WITH EXTENDED RELEASE USING A THERMAL CONVERSION AND METHOD FOR THE PRODUCTION THEREOF
JP3466921B2 (en) * 1998-06-03 2003-11-17 大塚製薬株式会社 Taste masking pharmaceutical formulation
JP2001270821A (en) * 2000-03-23 2001-10-02 Eisai Co Ltd Powder medicine having excellent taking easiness
JP2001302497A (en) * 2000-04-21 2001-10-31 Eisai Co Ltd Powdery preparation excellent in miscibility
JP4300821B2 (en) * 2002-03-05 2009-07-22 住友化学株式会社 Amino acid compounds
JP3797605B2 (en) * 2002-03-20 2006-07-19 旭化成ファーマ株式会社 Method for producing granular coated preparation

Also Published As

Publication number Publication date
JPWO2005039538A1 (en) 2007-11-22
KR20060095564A (en) 2006-08-31
CN1874759A (en) 2006-12-06
WO2005039538A1 (en) 2005-05-06
JP3981134B2 (en) 2007-09-26
TW200515923A (en) 2005-05-16
CN100528233C (en) 2009-08-19
KR101168189B1 (en) 2012-07-25

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Legal Events

Date Code Title Description
MM4A Annulment or lapse of patent due to non-payment of fees