KR101150627B1 - Ｎ-알킬-2(하이드록시-4 벤조일)-3 벤조퓨란의 제조 방법및 이의 중간 생성물 - Google Patents

Ｎ-알킬-2(하이드록시-4 벤조일)-3 벤조퓨란의 제조 방법및 이의 중간 생성물 Download PDF

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Publication number
KR101150627B1
KR101150627B1 KR1020067012489A KR20067012489A KR101150627B1 KR 101150627 B1 KR101150627 B1 KR 101150627B1 KR 1020067012489 A KR1020067012489 A KR 1020067012489A KR 20067012489 A KR20067012489 A KR 20067012489A KR 101150627 B1 KR101150627 B1 KR 101150627B1
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South Korea
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formula
compound
alkyl
halide
radical
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Korean (ko)
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KR20060111608A (ko
Inventor
알랑 쇼티텡
프랑수아 블레거
프랑수아즈 몰다크
제롬 피론
Original Assignee
클라리언트 스페셜티 파인 케미칼스 (프랑스)
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Publication of KR101150627B1 publication Critical patent/KR101150627B1/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
KR1020067012489A 2003-12-24 2004-12-15 Ｎ-알킬-2(하이드록시-4 벤조일)-3 벤조퓨란의 제조 방법및 이의 중간 생성물 Expired - Fee Related KR101150627B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0315398A FR2864536B1 (fr) 2003-12-24 2003-12-24 Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
FR0315398 2003-12-24
PCT/IB2004/004158 WO2005066149A1 (en) 2003-12-24 2004-12-15 Process for the preperation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof

Publications (2)

Publication Number Publication Date
KR20060111608A KR20060111608A (ko) 2006-10-27
KR101150627B1 true KR101150627B1 (ko) 2012-06-01

Family

ID=34639607

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020067012489A Expired - Fee Related KR101150627B1 (ko) 2003-12-24 2004-12-15 Ｎ-알킬-2(하이드록시-4 벤조일)-3 벤조퓨란의 제조 방법및 이의 중간 생성물

Country Status (11)

Country Link
US (1) US7544817B2 (enExample)
EP (2) EP1699772B1 (enExample)
JP (2) JP4896735B2 (enExample)
KR (1) KR101150627B1 (enExample)
CN (2) CN100475801C (enExample)
DK (1) DK1699772T3 (enExample)
ES (1) ES2400943T3 (enExample)
FR (1) FR2864536B1 (enExample)
NO (1) NO20062936L (enExample)
TW (1) TWI365878B (enExample)
WO (1) WO2005066149A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2914644B1 (fr) * 2007-04-06 2009-06-05 Finorga Soc Par Actions Simpli Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane
GB0719180D0 (en) * 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
NZ588623A (en) 2008-04-17 2012-11-30 Sanofi Aventis Use of a medicament containing dronedarone with food for preventing cardiovascular hospitalization
EP2246341A1 (en) 2009-01-23 2010-11-03 Lonza Ltd. Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans
IT1398317B1 (it) * 2010-02-23 2013-02-22 Chimico Internaz Spa Lab Nuovo procedimento per la preparazione del dronedarone.
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
EP2452938A1 (en) 2010-11-12 2012-05-16 LEK Pharmaceuticals d.d. Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives
FR2973027A1 (fr) * 2011-03-24 2012-09-28 Sanofi Aventis Procede de synthese de derives de cetobenzofurane
CN103265513A (zh) * 2013-03-25 2013-08-28 德州学院 制备2-烷基-3-(4-羟基苯甲酰基)苯并呋喃的方法
EP4375276A4 (en) * 2021-07-21 2025-04-16 Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. COMPOUND FOR THE TREATMENT OF A DISEASE ASSOCIATED WITH ISCHEMIC BRAIN INJURY

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058519A1 (en) 1998-05-12 1999-11-18 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1382742A (en) * 1972-09-19 1975-02-05 Labaz Benzofuran derivatives and process for preparing the same
GB1456323A (en) * 1974-06-06 1976-11-24 Labaz Benzothiophenes process for preparing them and pharmaceutical compositions containing the same
US3983245A (en) * 1975-02-06 1976-09-28 Smithkline Corporation Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4831054A (en) * 1988-04-18 1989-05-16 Taro Pharmaceuticals, Ltd. 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
FR2653431B1 (fr) * 1989-10-23 1994-05-27 Sanofi Sa Procede de preparation de derives de benzoyl-3 benzofuranne.
JP2873599B2 (ja) * 1990-03-09 1999-03-24 寿製薬株式会社 新規ベンゾフラン誘導体、尿酸排泄剤及びその製法
FR2665444B1 (fr) 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
JPH06184132A (ja) * 1992-12-22 1994-07-05 Kotobuki Seiyaku Kk ベンゾフラン誘導体及びその製造方法並びに尿酸排泄剤
GB9416219D0 (en) * 1994-08-11 1994-10-05 Karobio Ab Receptor ligands
FR2803846B1 (fr) 2000-01-17 2002-04-05 Clariant France Sa 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058519A1 (en) 1998-05-12 1999-11-18 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Also Published As

Publication number Publication date
DK1699772T3 (da) 2013-05-27
EP2508517A1 (en) 2012-10-10
NO20062936L (no) 2006-09-22
CN1898226A (zh) 2007-01-17
CN101486698B (zh) 2011-07-27
US7544817B2 (en) 2009-06-09
CN101486698A (zh) 2009-07-22
US20070155831A1 (en) 2007-07-05
TWI365878B (en) 2012-06-11
TW200526616A (en) 2005-08-16
CN100475801C (zh) 2009-04-08
JP2007517012A (ja) 2007-06-28
JP4896735B2 (ja) 2012-03-14
HK1097835A1 (zh) 2007-07-06
KR20060111608A (ko) 2006-10-27
FR2864536B1 (fr) 2006-03-17
JP2012012400A (ja) 2012-01-19
EP1699772A1 (en) 2006-09-13
FR2864536A1 (fr) 2005-07-01
WO2005066149A1 (en) 2005-07-21
EP1699772B1 (en) 2013-02-20
JP5400840B2 (ja) 2014-01-29
ES2400943T3 (es) 2013-04-15

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