NO20062936L - Fremgangsmate for fremstilling av N-alkyl-2(hydroksy-4-benzoyl)-3-benzofuraner og dets mellomprodukter derav - Google Patents
Fremgangsmate for fremstilling av N-alkyl-2(hydroksy-4-benzoyl)-3-benzofuraner og dets mellomprodukter deravInfo
- Publication number
- NO20062936L NO20062936L NO20062936A NO20062936A NO20062936L NO 20062936 L NO20062936 L NO 20062936L NO 20062936 A NO20062936 A NO 20062936A NO 20062936 A NO20062936 A NO 20062936A NO 20062936 L NO20062936 L NO 20062936L
- Authority
- NO
- Norway
- Prior art keywords
- intermediates
- alkyl
- benzofurans
- benzoyl
- hydroxy
- Prior art date
Links
- 239000000543 intermediate Substances 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000005843 halogen group Chemical group 0.000 abstract 1
- BLNWTAHYTCHDJH-UHFFFAOYSA-O hydroxy(oxo)azanium Chemical compound O[NH+]=O BLNWTAHYTCHDJH-UHFFFAOYSA-O 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D307/80—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0315398A FR2864536B1 (fr) | 2003-12-24 | 2003-12-24 | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
| PCT/IB2004/004158 WO2005066149A1 (en) | 2003-12-24 | 2004-12-15 | Process for the preperation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20062936L true NO20062936L (no) | 2006-09-22 |
Family
ID=34639607
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20062936A NO20062936L (no) | 2003-12-24 | 2006-06-23 | Fremgangsmate for fremstilling av N-alkyl-2(hydroksy-4-benzoyl)-3-benzofuraner og dets mellomprodukter derav |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7544817B2 (enExample) |
| EP (2) | EP1699772B1 (enExample) |
| JP (2) | JP4896735B2 (enExample) |
| KR (1) | KR101150627B1 (enExample) |
| CN (2) | CN100475801C (enExample) |
| DK (1) | DK1699772T3 (enExample) |
| ES (1) | ES2400943T3 (enExample) |
| FR (1) | FR2864536B1 (enExample) |
| NO (1) | NO20062936L (enExample) |
| TW (1) | TWI365878B (enExample) |
| WO (1) | WO2005066149A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2914644B1 (fr) * | 2007-04-06 | 2009-06-05 | Finorga Soc Par Actions Simpli | Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane |
| GB0719180D0 (en) * | 2007-10-02 | 2007-11-14 | Cambrex Karlskoga Ab | New process |
| NZ588623A (en) | 2008-04-17 | 2012-11-30 | Sanofi Aventis | Use of a medicament containing dronedarone with food for preventing cardiovascular hospitalization |
| EP2246341A1 (en) | 2009-01-23 | 2010-11-03 | Lonza Ltd. | Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans |
| IT1398317B1 (it) * | 2010-02-23 | 2013-02-22 | Chimico Internaz Spa Lab | Nuovo procedimento per la preparazione del dronedarone. |
| US8602215B2 (en) | 2010-06-30 | 2013-12-10 | Sanofi | Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation |
| EP2452938A1 (en) | 2010-11-12 | 2012-05-16 | LEK Pharmaceuticals d.d. | Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives |
| FR2973027A1 (fr) * | 2011-03-24 | 2012-09-28 | Sanofi Aventis | Procede de synthese de derives de cetobenzofurane |
| CN103265513A (zh) * | 2013-03-25 | 2013-08-28 | 德州学院 | 制备2-烷基-3-(4-羟基苯甲酰基)苯并呋喃的方法 |
| EP4375276A4 (en) * | 2021-07-21 | 2025-04-16 | Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. | COMPOUND FOR THE TREATMENT OF A DISEASE ASSOCIATED WITH ISCHEMIC BRAIN INJURY |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1382742A (en) * | 1972-09-19 | 1975-02-05 | Labaz | Benzofuran derivatives and process for preparing the same |
| GB1456323A (en) * | 1974-06-06 | 1976-11-24 | Labaz | Benzothiophenes process for preparing them and pharmaceutical compositions containing the same |
| US3983245A (en) * | 1975-02-06 | 1976-09-28 | Smithkline Corporation | Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes |
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4831054A (en) * | 1988-04-18 | 1989-05-16 | Taro Pharmaceuticals, Ltd. | 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia |
| FR2653431B1 (fr) * | 1989-10-23 | 1994-05-27 | Sanofi Sa | Procede de preparation de derives de benzoyl-3 benzofuranne. |
| JP2873599B2 (ja) * | 1990-03-09 | 1999-03-24 | 寿製薬株式会社 | 新規ベンゾフラン誘導体、尿酸排泄剤及びその製法 |
| FR2665444B1 (fr) | 1990-08-06 | 1992-11-27 | Sanofi Sa | Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant. |
| JPH06184132A (ja) * | 1992-12-22 | 1994-07-05 | Kotobuki Seiyaku Kk | ベンゾフラン誘導体及びその製造方法並びに尿酸排泄剤 |
| GB9416219D0 (en) * | 1994-08-11 | 1994-10-05 | Karobio Ab | Receptor ligands |
| JP2002514636A (ja) * | 1998-05-12 | 2002-05-21 | アメリカン・ホーム・プロダクツ・コーポレイション | インスリン抵抗性または高血糖症の治療に有用なフェニルオキソ−酢酸類 |
| FR2803846B1 (fr) | 2000-01-17 | 2002-04-05 | Clariant France Sa | 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation |
-
2003
- 2003-12-24 FR FR0315398A patent/FR2864536B1/fr not_active Expired - Fee Related
-
2004
- 2004-12-15 DK DK04801395.7T patent/DK1699772T3/da active
- 2004-12-15 JP JP2006546365A patent/JP4896735B2/ja not_active Expired - Fee Related
- 2004-12-15 WO PCT/IB2004/004158 patent/WO2005066149A1/en not_active Ceased
- 2004-12-15 EP EP04801395A patent/EP1699772B1/en not_active Expired - Lifetime
- 2004-12-15 US US10/584,440 patent/US7544817B2/en not_active Expired - Fee Related
- 2004-12-15 ES ES04801395T patent/ES2400943T3/es not_active Expired - Lifetime
- 2004-12-15 CN CNB2004800382852A patent/CN100475801C/zh not_active Expired - Fee Related
- 2004-12-15 EP EP12003772A patent/EP2508517A1/en not_active Withdrawn
- 2004-12-15 KR KR1020067012489A patent/KR101150627B1/ko not_active Expired - Fee Related
- 2004-12-15 CN CN200910006741XA patent/CN101486698B/zh not_active Expired - Fee Related
- 2004-12-22 TW TW093140136A patent/TWI365878B/zh not_active IP Right Cessation
-
2006
- 2006-06-23 NO NO20062936A patent/NO20062936L/no unknown
-
2011
- 2011-08-11 JP JP2011175599A patent/JP5400840B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DK1699772T3 (da) | 2013-05-27 |
| EP2508517A1 (en) | 2012-10-10 |
| KR101150627B1 (ko) | 2012-06-01 |
| CN1898226A (zh) | 2007-01-17 |
| CN101486698B (zh) | 2011-07-27 |
| US7544817B2 (en) | 2009-06-09 |
| CN101486698A (zh) | 2009-07-22 |
| US20070155831A1 (en) | 2007-07-05 |
| TWI365878B (en) | 2012-06-11 |
| TW200526616A (en) | 2005-08-16 |
| CN100475801C (zh) | 2009-04-08 |
| JP2007517012A (ja) | 2007-06-28 |
| JP4896735B2 (ja) | 2012-03-14 |
| HK1097835A1 (zh) | 2007-07-06 |
| KR20060111608A (ko) | 2006-10-27 |
| FR2864536B1 (fr) | 2006-03-17 |
| JP2012012400A (ja) | 2012-01-19 |
| EP1699772A1 (en) | 2006-09-13 |
| FR2864536A1 (fr) | 2005-07-01 |
| WO2005066149A1 (en) | 2005-07-21 |
| EP1699772B1 (en) | 2013-02-20 |
| JP5400840B2 (ja) | 2014-01-29 |
| ES2400943T3 (es) | 2013-04-15 |
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