IT1398317B1 - Nuovo procedimento per la preparazione del dronedarone. - Google Patents
Nuovo procedimento per la preparazione del dronedarone.Info
- Publication number
- IT1398317B1 IT1398317B1 ITMI2010A000284A ITMI20100284A IT1398317B1 IT 1398317 B1 IT1398317 B1 IT 1398317B1 IT MI2010A000284 A ITMI2010A000284 A IT MI2010A000284A IT MI20100284 A ITMI20100284 A IT MI20100284A IT 1398317 B1 IT1398317 B1 IT 1398317B1
- Authority
- IT
- Italy
- Prior art keywords
- dronedarone
- preparation
- new procedure
- procedure
- new
- Prior art date
Links
- ZQTNQVWKHCQYLQ-UHFFFAOYSA-N dronedarone Chemical compound C1=CC(OCCCN(CCCC)CCCC)=CC=C1C(=O)C1=C(CCCC)OC2=CC=C(NS(C)(=O)=O)C=C12 ZQTNQVWKHCQYLQ-UHFFFAOYSA-N 0.000 title 1
- 229960002084 dronedarone Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2010A000284A IT1398317B1 (it) | 2010-02-23 | 2010-02-23 | Nuovo procedimento per la preparazione del dronedarone. |
EP11709460.7A EP2539331B1 (en) | 2010-02-23 | 2011-01-26 | Novel process for the manufacture of dronedarone |
EA201201174A EA019860B1 (ru) | 2010-02-23 | 2011-01-26 | Новый способ получения дронедарона |
US13/580,005 US8536350B2 (en) | 2010-02-23 | 2011-01-26 | Process for the manufacture of dronedarone |
PCT/IB2011/000113 WO2011104591A1 (en) | 2010-02-23 | 2011-01-26 | Novel process for the manufacture of dronedarone |
CA2788016A CA2788016A1 (en) | 2010-02-23 | 2011-01-26 | Novel process for the manufacture of dronedarone |
CN201180010578.XA CN102770420B (zh) | 2010-02-23 | 2011-01-26 | 制备决奈达隆的新方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI2010A000284A IT1398317B1 (it) | 2010-02-23 | 2010-02-23 | Nuovo procedimento per la preparazione del dronedarone. |
Publications (2)
Publication Number | Publication Date |
---|---|
ITMI20100284A1 ITMI20100284A1 (it) | 2011-08-24 |
IT1398317B1 true IT1398317B1 (it) | 2013-02-22 |
Family
ID=42746617
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI2010A000284A IT1398317B1 (it) | 2010-02-23 | 2010-02-23 | Nuovo procedimento per la preparazione del dronedarone. |
Country Status (7)
Country | Link |
---|---|
US (1) | US8536350B2 (it) |
EP (1) | EP2539331B1 (it) |
CN (1) | CN102770420B (it) |
CA (1) | CA2788016A1 (it) |
EA (1) | EA019860B1 (it) |
IT (1) | IT1398317B1 (it) |
WO (1) | WO2011104591A1 (it) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2958290B1 (fr) | 2010-03-30 | 2012-10-19 | Sanofi Aventis | Procede de preparation de derives de sulfonamido-benzofurane |
HUP1000330A2 (en) | 2010-06-18 | 2011-12-28 | Sanofi Sa | Process for the preparation of dronedarone and the novel intermediates |
HUP1100167A2 (en) | 2011-03-29 | 2012-11-28 | Sanofi Sa | Process for preparation of dronedarone by mesylation |
HUP1100165A2 (en) | 2011-03-29 | 2012-12-28 | Sanofi Sa | Process for preparation of dronedarone by n-butylation |
FR2983198B1 (fr) * | 2011-11-29 | 2013-11-15 | Sanofi Sa | Procede de preparation de derives de 5-amino-benzoyl-benzofurane |
EP2617718A1 (en) | 2012-01-20 | 2013-07-24 | Sanofi | Process for preparation of dronedarone by the use of dibutylaminopropanol reagent |
WO2013121235A2 (en) | 2012-02-13 | 2013-08-22 | Sanofi | Process for preparation of dronedarone by removal of hydroxyl group |
WO2013121234A1 (en) | 2012-02-14 | 2013-08-22 | Sanofi | Process for the preparation of dronedarone by oxidation of a sulphenyl group |
WO2013124745A1 (en) | 2012-02-22 | 2013-08-29 | Sanofi | Process for preparation of dronedarone by oxidation of a hydroxyl group |
WO2013178337A1 (en) | 2012-05-31 | 2013-12-05 | Sanofi | Process for preparation of dronedarone by grignard reaction |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2817865B1 (fr) * | 2000-12-11 | 2005-02-18 | Sanofi Synthelabo | Derive aminoalkoxybenzoyle sous forme de sel, son procede de preparation et son utilisation comme intermediaire de synthese |
IL146389A0 (en) * | 2001-11-08 | 2002-07-25 | Isp Finetech Ltd | Process for the preparation of dronedarone |
FR2864536B1 (fr) * | 2003-12-24 | 2006-03-17 | Clariant France Sa | Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre |
GB0719180D0 (en) * | 2007-10-02 | 2007-11-14 | Cambrex Karlskoga Ab | New process |
HUP0900759A2 (en) * | 2009-12-08 | 2011-11-28 | Sanofi Aventis | Novel process for producing dronedarone |
-
2010
- 2010-02-23 IT ITMI2010A000284A patent/IT1398317B1/it active
-
2011
- 2011-01-26 CA CA2788016A patent/CA2788016A1/en not_active Abandoned
- 2011-01-26 CN CN201180010578.XA patent/CN102770420B/zh not_active Expired - Fee Related
- 2011-01-26 EP EP11709460.7A patent/EP2539331B1/en not_active Not-in-force
- 2011-01-26 EA EA201201174A patent/EA019860B1/ru not_active IP Right Cessation
- 2011-01-26 US US13/580,005 patent/US8536350B2/en not_active Expired - Fee Related
- 2011-01-26 WO PCT/IB2011/000113 patent/WO2011104591A1/en active Application Filing
Also Published As
Publication number | Publication date |
---|---|
WO2011104591A1 (en) | 2011-09-01 |
EA019860B1 (ru) | 2014-06-30 |
CN102770420A (zh) | 2012-11-07 |
US20120330037A1 (en) | 2012-12-27 |
CN102770420B (zh) | 2015-02-25 |
EA201201174A1 (ru) | 2013-01-30 |
CA2788016A1 (en) | 2011-09-01 |
ITMI20100284A1 (it) | 2011-08-24 |
EP2539331A1 (en) | 2013-01-02 |
EP2539331B1 (en) | 2014-10-08 |
US8536350B2 (en) | 2013-09-17 |
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