IT1398317B1 - Nuovo procedimento per la preparazione del dronedarone. - Google Patents

Nuovo procedimento per la preparazione del dronedarone.

Info

Publication number
IT1398317B1
IT1398317B1 ITMI2010A000284A ITMI20100284A IT1398317B1 IT 1398317 B1 IT1398317 B1 IT 1398317B1 IT MI2010A000284 A ITMI2010A000284 A IT MI2010A000284A IT MI20100284 A ITMI20100284 A IT MI20100284A IT 1398317 B1 IT1398317 B1 IT 1398317B1
Authority
IT
Italy
Prior art keywords
dronedarone
preparation
new procedure
procedure
new
Prior art date
Application number
ITMI2010A000284A
Other languages
English (en)
Inventor
Mara Sada
Stefano Maiorana
Antonio Nardi
Original Assignee
Chimico Internaz Spa Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chimico Internaz Spa Lab filed Critical Chimico Internaz Spa Lab
Priority to ITMI2010A000284A priority Critical patent/IT1398317B1/it
Priority to EP11709460.7A priority patent/EP2539331B1/en
Priority to EA201201174A priority patent/EA019860B1/ru
Priority to US13/580,005 priority patent/US8536350B2/en
Priority to PCT/IB2011/000113 priority patent/WO2011104591A1/en
Priority to CA2788016A priority patent/CA2788016A1/en
Priority to CN201180010578.XA priority patent/CN102770420B/zh
Publication of ITMI20100284A1 publication Critical patent/ITMI20100284A1/it
Application granted granted Critical
Publication of IT1398317B1 publication Critical patent/IT1398317B1/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ITMI2010A000284A 2010-02-23 2010-02-23 Nuovo procedimento per la preparazione del dronedarone. IT1398317B1 (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
ITMI2010A000284A IT1398317B1 (it) 2010-02-23 2010-02-23 Nuovo procedimento per la preparazione del dronedarone.
EP11709460.7A EP2539331B1 (en) 2010-02-23 2011-01-26 Novel process for the manufacture of dronedarone
EA201201174A EA019860B1 (ru) 2010-02-23 2011-01-26 Новый способ получения дронедарона
US13/580,005 US8536350B2 (en) 2010-02-23 2011-01-26 Process for the manufacture of dronedarone
PCT/IB2011/000113 WO2011104591A1 (en) 2010-02-23 2011-01-26 Novel process for the manufacture of dronedarone
CA2788016A CA2788016A1 (en) 2010-02-23 2011-01-26 Novel process for the manufacture of dronedarone
CN201180010578.XA CN102770420B (zh) 2010-02-23 2011-01-26 制备决奈达隆的新方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI2010A000284A IT1398317B1 (it) 2010-02-23 2010-02-23 Nuovo procedimento per la preparazione del dronedarone.

Publications (2)

Publication Number Publication Date
ITMI20100284A1 ITMI20100284A1 (it) 2011-08-24
IT1398317B1 true IT1398317B1 (it) 2013-02-22

Family

ID=42746617

Family Applications (1)

Application Number Title Priority Date Filing Date
ITMI2010A000284A IT1398317B1 (it) 2010-02-23 2010-02-23 Nuovo procedimento per la preparazione del dronedarone.

Country Status (7)

Country Link
US (1) US8536350B2 (it)
EP (1) EP2539331B1 (it)
CN (1) CN102770420B (it)
CA (1) CA2788016A1 (it)
EA (1) EA019860B1 (it)
IT (1) IT1398317B1 (it)
WO (1) WO2011104591A1 (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2958290B1 (fr) 2010-03-30 2012-10-19 Sanofi Aventis Procede de preparation de derives de sulfonamido-benzofurane
HUP1000330A2 (en) 2010-06-18 2011-12-28 Sanofi Sa Process for the preparation of dronedarone and the novel intermediates
HUP1100167A2 (en) 2011-03-29 2012-11-28 Sanofi Sa Process for preparation of dronedarone by mesylation
HUP1100165A2 (en) 2011-03-29 2012-12-28 Sanofi Sa Process for preparation of dronedarone by n-butylation
FR2983198B1 (fr) * 2011-11-29 2013-11-15 Sanofi Sa Procede de preparation de derives de 5-amino-benzoyl-benzofurane
EP2617718A1 (en) 2012-01-20 2013-07-24 Sanofi Process for preparation of dronedarone by the use of dibutylaminopropanol reagent
WO2013121235A2 (en) 2012-02-13 2013-08-22 Sanofi Process for preparation of dronedarone by removal of hydroxyl group
WO2013121234A1 (en) 2012-02-14 2013-08-22 Sanofi Process for the preparation of dronedarone by oxidation of a sulphenyl group
WO2013124745A1 (en) 2012-02-22 2013-08-29 Sanofi Process for preparation of dronedarone by oxidation of a hydroxyl group
WO2013178337A1 (en) 2012-05-31 2013-12-05 Sanofi Process for preparation of dronedarone by grignard reaction

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2817865B1 (fr) * 2000-12-11 2005-02-18 Sanofi Synthelabo Derive aminoalkoxybenzoyle sous forme de sel, son procede de preparation et son utilisation comme intermediaire de synthese
IL146389A0 (en) * 2001-11-08 2002-07-25 Isp Finetech Ltd Process for the preparation of dronedarone
FR2864536B1 (fr) * 2003-12-24 2006-03-17 Clariant France Sa Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
GB0719180D0 (en) * 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
HUP0900759A2 (en) * 2009-12-08 2011-11-28 Sanofi Aventis Novel process for producing dronedarone

Also Published As

Publication number Publication date
WO2011104591A1 (en) 2011-09-01
EA019860B1 (ru) 2014-06-30
CN102770420A (zh) 2012-11-07
US20120330037A1 (en) 2012-12-27
CN102770420B (zh) 2015-02-25
EA201201174A1 (ru) 2013-01-30
CA2788016A1 (en) 2011-09-01
ITMI20100284A1 (it) 2011-08-24
EP2539331A1 (en) 2013-01-02
EP2539331B1 (en) 2014-10-08
US8536350B2 (en) 2013-09-17

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