ES2400943T3 - Proceso para la preparación de N-alquil-2(hidroxi-4-benzoil)-3-benzofuranos y compuestos intermedios de los mismos - Google Patents

Proceso para la preparación de N-alquil-2(hidroxi-4-benzoil)-3-benzofuranos y compuestos intermedios de los mismos Download PDF

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Publication number
ES2400943T3
ES2400943T3 ES04801395T ES04801395T ES2400943T3 ES 2400943 T3 ES2400943 T3 ES 2400943T3 ES 04801395 T ES04801395 T ES 04801395T ES 04801395 T ES04801395 T ES 04801395T ES 2400943 T3 ES2400943 T3 ES 2400943T3
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ES
Spain
Prior art keywords
formula
alkyl
compound
process according
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES04801395T
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English (en)
Spanish (es)
Inventor
Alain Shoutteeten
François BLEGER
Françoise Mordacq
Jérôme PIRON
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Clariant Speciality Fine Chemicals France
Original Assignee
Clariant Speciality Fine Chemicals France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant Speciality Fine Chemicals France filed Critical Clariant Speciality Fine Chemicals France
Application granted granted Critical
Publication of ES2400943T3 publication Critical patent/ES2400943T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ES04801395T 2003-12-24 2004-12-15 Proceso para la preparación de N-alquil-2(hidroxi-4-benzoil)-3-benzofuranos y compuestos intermedios de los mismos Expired - Lifetime ES2400943T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0315398A FR2864536B1 (fr) 2003-12-24 2003-12-24 Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
FR0315398 2003-12-24
PCT/IB2004/004158 WO2005066149A1 (en) 2003-12-24 2004-12-15 Process for the preperation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof

Publications (1)

Publication Number Publication Date
ES2400943T3 true ES2400943T3 (es) 2013-04-15

Family

ID=34639607

Family Applications (1)

Application Number Title Priority Date Filing Date
ES04801395T Expired - Lifetime ES2400943T3 (es) 2003-12-24 2004-12-15 Proceso para la preparación de N-alquil-2(hidroxi-4-benzoil)-3-benzofuranos y compuestos intermedios de los mismos

Country Status (11)

Country Link
US (1) US7544817B2 (enExample)
EP (2) EP1699772B1 (enExample)
JP (2) JP4896735B2 (enExample)
KR (1) KR101150627B1 (enExample)
CN (2) CN100475801C (enExample)
DK (1) DK1699772T3 (enExample)
ES (1) ES2400943T3 (enExample)
FR (1) FR2864536B1 (enExample)
NO (1) NO20062936L (enExample)
TW (1) TWI365878B (enExample)
WO (1) WO2005066149A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2914644B1 (fr) * 2007-04-06 2009-06-05 Finorga Soc Par Actions Simpli Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane
GB0719180D0 (en) * 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
NZ588623A (en) 2008-04-17 2012-11-30 Sanofi Aventis Use of a medicament containing dronedarone with food for preventing cardiovascular hospitalization
EP2246341A1 (en) 2009-01-23 2010-11-03 Lonza Ltd. Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans
IT1398317B1 (it) * 2010-02-23 2013-02-22 Chimico Internaz Spa Lab Nuovo procedimento per la preparazione del dronedarone.
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
EP2452938A1 (en) 2010-11-12 2012-05-16 LEK Pharmaceuticals d.d. Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives
FR2973027A1 (fr) * 2011-03-24 2012-09-28 Sanofi Aventis Procede de synthese de derives de cetobenzofurane
CN103265513A (zh) * 2013-03-25 2013-08-28 德州学院 制备2-烷基-3-(4-羟基苯甲酰基)苯并呋喃的方法
EP4375276A4 (en) * 2021-07-21 2025-04-16 Jiangsu Chia Tai Fenghai Pharmaceutical Co., Ltd. COMPOUND FOR THE TREATMENT OF A DISEASE ASSOCIATED WITH ISCHEMIC BRAIN INJURY

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1382742A (en) * 1972-09-19 1975-02-05 Labaz Benzofuran derivatives and process for preparing the same
GB1456323A (en) * 1974-06-06 1976-11-24 Labaz Benzothiophenes process for preparing them and pharmaceutical compositions containing the same
US3983245A (en) * 1975-02-06 1976-09-28 Smithkline Corporation Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4831054A (en) * 1988-04-18 1989-05-16 Taro Pharmaceuticals, Ltd. 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
FR2653431B1 (fr) * 1989-10-23 1994-05-27 Sanofi Sa Procede de preparation de derives de benzoyl-3 benzofuranne.
JP2873599B2 (ja) * 1990-03-09 1999-03-24 寿製薬株式会社 新規ベンゾフラン誘導体、尿酸排泄剤及びその製法
FR2665444B1 (fr) 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
JPH06184132A (ja) * 1992-12-22 1994-07-05 Kotobuki Seiyaku Kk ベンゾフラン誘導体及びその製造方法並びに尿酸排泄剤
GB9416219D0 (en) * 1994-08-11 1994-10-05 Karobio Ab Receptor ligands
JP2002514636A (ja) * 1998-05-12 2002-05-21 アメリカン・ホーム・プロダクツ・コーポレイション インスリン抵抗性または高血糖症の治療に有用なフェニルオキソ−酢酸類
FR2803846B1 (fr) 2000-01-17 2002-04-05 Clariant France Sa 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation

Also Published As

Publication number Publication date
DK1699772T3 (da) 2013-05-27
EP2508517A1 (en) 2012-10-10
NO20062936L (no) 2006-09-22
KR101150627B1 (ko) 2012-06-01
CN1898226A (zh) 2007-01-17
CN101486698B (zh) 2011-07-27
US7544817B2 (en) 2009-06-09
CN101486698A (zh) 2009-07-22
US20070155831A1 (en) 2007-07-05
TWI365878B (en) 2012-06-11
TW200526616A (en) 2005-08-16
CN100475801C (zh) 2009-04-08
JP2007517012A (ja) 2007-06-28
JP4896735B2 (ja) 2012-03-14
HK1097835A1 (zh) 2007-07-06
KR20060111608A (ko) 2006-10-27
FR2864536B1 (fr) 2006-03-17
JP2012012400A (ja) 2012-01-19
EP1699772A1 (en) 2006-09-13
FR2864536A1 (fr) 2005-07-01
WO2005066149A1 (en) 2005-07-21
EP1699772B1 (en) 2013-02-20
JP5400840B2 (ja) 2014-01-29

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