DK1699772T3 - Fremgangsmåde til fremstilling af 2-(n-alkyl)-3-(4-hydroxybenzoyl)benzofuraner samt mellemprodukter dertil - Google Patents

Fremgangsmåde til fremstilling af 2-(n-alkyl)-3-(4-hydroxybenzoyl)benzofuraner samt mellemprodukter dertil

Info

Publication number
DK1699772T3
DK1699772T3 DK04801395.7T DK04801395T DK1699772T3 DK 1699772 T3 DK1699772 T3 DK 1699772T3 DK 04801395 T DK04801395 T DK 04801395T DK 1699772 T3 DK1699772 T3 DK 1699772T3
Authority
DK
Denmark
Prior art keywords
benzofurans
hydroxybenzoyl
alkyl
preparation
intermediates therefor
Prior art date
Application number
DK04801395.7T
Other languages
English (en)
Inventor
Francois Bleger
Francoise Mordacq
Jera Me Piron
Alain Shoutteeten
Original Assignee
Clariant Specialty Fine Chem F
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Clariant Specialty Fine Chem F filed Critical Clariant Specialty Fine Chem F
Application granted granted Critical
Publication of DK1699772T3 publication Critical patent/DK1699772T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Furan Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK04801395.7T 2003-12-24 2004-12-15 Fremgangsmåde til fremstilling af 2-(n-alkyl)-3-(4-hydroxybenzoyl)benzofuraner samt mellemprodukter dertil DK1699772T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0315398A FR2864536B1 (fr) 2003-12-24 2003-12-24 Procede de preparation de n-alkyl-2 (hydroxy-4-benzoyl)-3 benzofurannes et intermediaires pour sa mise en oeuvre
PCT/IB2004/004158 WO2005066149A1 (en) 2003-12-24 2004-12-15 Process for the preperation of n-alkyl-2(hydroxy-4 benzoyl)-3 benzofurans and its intermediates thereof

Publications (1)

Publication Number Publication Date
DK1699772T3 true DK1699772T3 (da) 2013-05-27

Family

ID=34639607

Family Applications (1)

Application Number Title Priority Date Filing Date
DK04801395.7T DK1699772T3 (da) 2003-12-24 2004-12-15 Fremgangsmåde til fremstilling af 2-(n-alkyl)-3-(4-hydroxybenzoyl)benzofuraner samt mellemprodukter dertil

Country Status (12)

Country Link
US (1) US7544817B2 (da)
EP (2) EP1699772B1 (da)
JP (2) JP4896735B2 (da)
KR (1) KR101150627B1 (da)
CN (2) CN100475801C (da)
DK (1) DK1699772T3 (da)
ES (1) ES2400943T3 (da)
FR (1) FR2864536B1 (da)
HK (1) HK1097835A1 (da)
NO (1) NO20062936L (da)
TW (1) TWI365878B (da)
WO (1) WO2005066149A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2914644B1 (fr) * 2007-04-06 2009-06-05 Finorga Soc Par Actions Simpli Procede de preparation de 2-(n-butyl)-3-(4-hydroxybenzoyl) -5-nitrobenzofurane
GB0719180D0 (en) * 2007-10-02 2007-11-14 Cambrex Karlskoga Ab New process
NZ588623A (en) 2008-04-17 2012-11-30 Sanofi Aventis Use of a medicament containing dronedarone with food for preventing cardiovascular hospitalization
EP2246341A1 (en) 2009-01-23 2010-11-03 Lonza Ltd. Process for preparing 2-Alkyl-3-aroyl-5-nitro-benzofurans
IT1398317B1 (it) * 2010-02-23 2013-02-22 Chimico Internaz Spa Lab Nuovo procedimento per la preparazione del dronedarone.
US8602215B2 (en) 2010-06-30 2013-12-10 Sanofi Methods for reducing the risk of an adverse dronedarone/beta-blockers interaction in a patient suffering from atrial fibrillation
EP2452938A1 (en) 2010-11-12 2012-05-16 LEK Pharmaceuticals d.d. Process for the preparation of 3-aroyl-5-aminobenzofuran derivatives
FR2973027A1 (fr) * 2011-03-24 2012-09-28 Sanofi Aventis Procede de synthese de derives de cetobenzofurane
CN103265513A (zh) * 2013-03-25 2013-08-28 德州学院 制备2-烷基-3-(4-羟基苯甲酰基)苯并呋喃的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1382742A (en) * 1972-09-19 1975-02-05 Labaz Benzofuran derivatives and process for preparing the same
GB1456323A (en) * 1974-06-06 1976-11-24 Labaz Benzothiophenes process for preparing them and pharmaceutical compositions containing the same
US3983245A (en) * 1975-02-06 1976-09-28 Smithkline Corporation Certain 4-(3-azacycloalkoxy or azacycloalkylmethoxy)benzoylbenzofurans or benzothiophenes
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4831054A (en) * 1988-04-18 1989-05-16 Taro Pharmaceuticals, Ltd. 2-Alkyl-3-benzoylbenzofurans useful for treating cardiac arrhythmia
FR2653431B1 (fr) * 1989-10-23 1994-05-27 Sanofi Sa Procede de preparation de derives de benzoyl-3 benzofuranne.
JP2873599B2 (ja) * 1990-03-09 1999-03-24 寿製薬株式会社 新規ベンゾフラン誘導体、尿酸排泄剤及びその製法
FR2665444B1 (fr) * 1990-08-06 1992-11-27 Sanofi Sa Derives d'amino-benzofuranne, benzothiophene ou indole, leur procede de preparation ainsi que les compositions les contenant.
JPH06184132A (ja) * 1992-12-22 1994-07-05 Kotobuki Seiyaku Kk ベンゾフラン誘導体及びその製造方法並びに尿酸排泄剤
GB9416219D0 (en) 1994-08-11 1994-10-05 Karobio Ab Receptor ligands
EP1077965A1 (en) * 1998-05-12 2001-02-28 American Home Products Corporation Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia
FR2803846B1 (fr) * 2000-01-17 2002-04-05 Clariant France Sa 3-(1-hydroxy-pentylidene)-5-nitro-3h-benzofuran-2-one, son procede de preparation et son utilisation

Also Published As

Publication number Publication date
HK1097835A1 (en) 2007-07-06
TW200526616A (en) 2005-08-16
CN101486698B (zh) 2011-07-27
JP2012012400A (ja) 2012-01-19
CN101486698A (zh) 2009-07-22
EP1699772A1 (en) 2006-09-13
US20070155831A1 (en) 2007-07-05
EP2508517A1 (en) 2012-10-10
ES2400943T3 (es) 2013-04-15
KR101150627B1 (ko) 2012-06-01
JP2007517012A (ja) 2007-06-28
CN1898226A (zh) 2007-01-17
KR20060111608A (ko) 2006-10-27
TWI365878B (en) 2012-06-11
US7544817B2 (en) 2009-06-09
WO2005066149A1 (en) 2005-07-21
EP1699772B1 (en) 2013-02-20
JP4896735B2 (ja) 2012-03-14
CN100475801C (zh) 2009-04-08
JP5400840B2 (ja) 2014-01-29
NO20062936L (no) 2006-09-22
FR2864536B1 (fr) 2006-03-17
FR2864536A1 (fr) 2005-07-01

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