KR100245284B1 - 이중 d-루프 형성의 진단학적 응용 - Google Patents

이중 d-루프 형성의 진단학적 응용 Download PDF

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Publication number
KR100245284B1
KR100245284B1 KR1019940700724A KR19940700724A KR100245284B1 KR 100245284 B1 KR100245284 B1 KR 100245284B1 KR 1019940700724 A KR1019940700724 A KR 1019940700724A KR 19940700724 A KR19940700724 A KR 19940700724A KR 100245284 B1 KR100245284 B1 KR 100245284B1
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South Korea
Prior art keywords
dna
probe
target
chain
double
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English (en)
Korean (ko)
Inventor
세나 엘리사피
칼호운 코넬리아제이
자링 데이비드에이
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이노우에 노리유끼
다이낑 고오교 가부시키가이샤
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Priority claimed from US07/520,321 external-priority patent/US5223414A/en
Priority claimed from US07/755,462 external-priority patent/US5273881A/en
Application filed by 이노우에 노리유끼, 다이낑 고오교 가부시키가이샤 filed Critical 이노우에 노리유끼
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/682—Signal amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Stabilization Of Oscillater, Synchronisation, Frequency Synthesizers (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
KR1019940700724A 1990-05-07 1992-09-04 이중 d-루프 형성의 진단학적 응용 Expired - Fee Related KR100245284B1 (ko)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US07/520,321 US5223414A (en) 1990-05-07 1990-05-07 Process for nucleic acid hybridization and amplification
US07/755,462 US5273881A (en) 1990-05-07 1991-09-04 Diagnostic applications of double D-loop formation
US7/755,462 1991-09-04
US91079192A 1992-07-09 1992-07-09
US7/910,791 1992-07-09
PCT/JP1992/001135 WO1993005178A1 (en) 1990-05-07 1992-09-04 Diagnostic applications of double d-loop formation

Publications (1)

Publication Number Publication Date
KR100245284B1 true KR100245284B1 (ko) 2000-03-02

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Application Number Title Priority Date Filing Date
KR1019940700724A Expired - Fee Related KR100245284B1 (ko) 1990-05-07 1992-09-04 이중 d-루프 형성의 진단학적 응용

Country Status (13)

Country Link
US (1) US5670316A (enExample)
EP (1) EP0612352B1 (enExample)
JP (1) JP2745816B2 (enExample)
KR (1) KR100245284B1 (enExample)
AT (1) ATE153707T1 (enExample)
AU (1) AU661505B2 (enExample)
CA (1) CA2116215C (enExample)
DE (1) DE69220084T2 (enExample)
DK (1) DK0612352T3 (enExample)
ES (1) ES2101867T3 (enExample)
FI (1) FI941016L (enExample)
NO (1) NO313557B1 (enExample)
WO (1) WO1993005178A1 (enExample)

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JP2007501003A (ja) * 2003-08-01 2007-01-25 ユー．エス． ジェノミクス， インコーポレイテッド 非切断条件下で核酸を分析するための配列特異的エンドヌクレアーゼの使用に関連した方法および組成物
WO2005017205A2 (en) * 2003-08-04 2005-02-24 U. S. Genomics, Inc. Nucleic acid mapping using linear analysis
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Also Published As

Publication number Publication date
EP0612352B1 (en) 1997-05-28
NO940744L (enExample) 1994-05-02
AU2540192A (en) 1993-04-05
DE69220084T2 (de) 1997-09-11
ATE153707T1 (de) 1997-06-15
DK0612352T3 (da) 1997-06-30
WO1993005178A1 (en) 1993-03-18
NO940744D0 (no) 1994-03-03
JPH06510201A (ja) 1994-11-17
JP2745816B2 (ja) 1998-04-28
FI941016A0 (fi) 1994-03-03
NO313557B1 (no) 2002-10-21
FI941016A7 (fi) 1994-05-03
FI941016L (fi) 1994-05-03
DE69220084D1 (de) 1997-07-03
ES2101867T3 (es) 1997-07-16
EP0612352A1 (en) 1994-08-31
CA2116215A1 (en) 1993-03-05
AU661505B2 (en) 1995-07-27
US5670316A (en) 1997-09-23
CA2116215C (en) 1998-12-22

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