KR0180248B1 - 항당뇨병약품 - Google Patents
항당뇨병약품 Download PDFInfo
- Publication number
- KR0180248B1 KR0180248B1 KR1019930700316A KR930700316A KR0180248B1 KR 0180248 B1 KR0180248 B1 KR 0180248B1 KR 1019930700316 A KR1019930700316 A KR 1019930700316A KR 930700316 A KR930700316 A KR 930700316A KR 0180248 B1 KR0180248 B1 KR 0180248B1
- Authority
- KR
- South Korea
- Prior art keywords
- carbostyryl
- salt
- bond
- active ingredient
- insulin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 239000004570 mortar (masonry) Substances 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical class CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 210000000496 pancreas Anatomy 0.000 description 1
- 229920001993 poloxamer 188 Polymers 0.000 description 1
- 229910000160 potassium phosphate Inorganic materials 0.000 description 1
- 235000011009 potassium phosphates Nutrition 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 description 1
- 235000010232 propyl p-hydroxybenzoate Nutrition 0.000 description 1
- 239000004405 propyl p-hydroxybenzoate Substances 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 125000001453 quaternary ammonium group Chemical group 0.000 description 1
- 208000037974 severe injury Diseases 0.000 description 1
- 230000009528 severe injury Effects 0.000 description 1
- 239000004208 shellac Substances 0.000 description 1
- ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 description 1
- 229940113147 shellac Drugs 0.000 description 1
- 235000013874 shellac Nutrition 0.000 description 1
- 235000020374 simple syrup Nutrition 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 235000015112 vegetable and seed oil Nutrition 0.000 description 1
- 239000008158 vegetable oil Substances 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP91-136465 | 1991-06-07 | ||
| JP13646591 | 1991-06-07 | ||
| PCT/JP1992/000689 WO1992021342A1 (en) | 1991-06-07 | 1992-05-28 | Antidiabetic |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR930701170A KR930701170A (ko) | 1993-06-11 |
| KR0180248B1 true KR0180248B1 (ko) | 1999-03-20 |
Family
ID=15175749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019930700316A Expired - Fee Related KR0180248B1 (ko) | 1991-06-07 | 1992-05-28 | 항당뇨병약품 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5480891A (enExample) |
| EP (1) | EP0543018B1 (enExample) |
| JP (1) | JP2608227B2 (enExample) |
| KR (1) | KR0180248B1 (enExample) |
| CA (1) | CA2088582A1 (enExample) |
| DE (1) | DE69207560T2 (enExample) |
| DK (1) | DK0543018T3 (enExample) |
| TW (1) | TW203007B (enExample) |
| WO (1) | WO1992021342A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013058627A3 (ko) * | 2011-10-21 | 2013-07-04 | 가톨릭대학교 산학협력단 | 레바미피드를 유효성분으로 포함하는 비만의 예방 또는 치료용 조성물 |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW227558B (enExample) * | 1992-05-14 | 1994-08-01 | Otsuka Pharma Co Ltd | |
| CA2150546C (en) * | 1993-10-21 | 2004-11-09 | Takahide Matsuda | Agent for inhibiting production of interleukin-8 |
| WO1995012579A1 (en) * | 1993-11-05 | 1995-05-11 | Otsuka Pharmaceutical Company, Limited | Bismuth salt of carbostyril derivatives for the treatment of peptic ulcers |
| AR004214A1 (es) * | 1995-10-12 | 1998-11-04 | Otsuka Pharma Co Ltd | Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas |
| IL121203A (en) * | 1996-07-01 | 2001-04-30 | Lilly Co Eli | 1, 2, 3, 4-tetrahydroisoquinidines, process for their preparation and pharmaceutical compositions containing the same for treating hyperglycemia and hyperlipidemia |
| EP0925063A4 (en) | 1996-07-01 | 2000-12-27 | Lilly Co Eli | Blood-glucose-lowering and lipid-lowering compounds |
| EP1212304A2 (en) | 1999-08-27 | 2002-06-12 | Eli Lilly And Company | Hypoglycemic sulfonyl pyrazolones and pyrazolines |
| JP4394686B2 (ja) | 2003-07-30 | 2010-01-06 | 大塚製薬株式会社 | 唾液分泌促進用医薬組成物およびその使用 |
| TWI340650B (en) * | 2004-01-21 | 2011-04-21 | Otsuka Pharma Co Ltd | Amine saly of carbostyril derivative |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE43079B1 (en) * | 1975-03-20 | 1980-12-17 | Ici Ltd | Quinolone derivatives |
| JPS6026797B2 (ja) * | 1976-07-12 | 1985-06-25 | 大塚製薬株式会社 | 新規なカルボスチリル誘導体 |
| JPS609511B2 (ja) * | 1976-07-16 | 1985-03-11 | 大塚製薬株式会社 | ５−カルボスチリルメタノ−ル誘導体 |
| JPS6037098B2 (ja) * | 1978-01-13 | 1985-08-24 | 大塚製薬株式会社 | ５―ホルミルカルボスチリル誘導体 |
| JPS597168A (ja) * | 1982-07-05 | 1984-01-14 | Otsuka Pharmaceut Co Ltd | カルボスチリル誘導体 |
| US4578381A (en) * | 1982-07-05 | 1986-03-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JP2812998B2 (ja) * | 1989-08-14 | 1998-10-22 | 大塚製薬 株式会社 | 胃炎治療剤 |
| JP2820739B2 (ja) * | 1989-10-28 | 1998-11-05 | 大塚製薬株式会社 | カルボスチリル誘導体の製造法 |
| JPH07112454A (ja) * | 1993-10-19 | 1995-05-02 | Sekisui Chem Co Ltd | プラスチック成形品のボス構造 |
-
1992
- 1992-05-28 DE DE69207560T patent/DE69207560T2/de not_active Expired - Fee Related
- 1992-05-28 DK DK92911055.9T patent/DK0543018T3/da active
- 1992-05-28 WO PCT/JP1992/000689 patent/WO1992021342A1/ja not_active Ceased
- 1992-05-28 CA CA002088582A patent/CA2088582A1/en not_active Abandoned
- 1992-05-28 EP EP92911055A patent/EP0543018B1/en not_active Expired - Lifetime
- 1992-05-28 KR KR1019930700316A patent/KR0180248B1/ko not_active Expired - Fee Related
- 1992-05-29 JP JP4138510A patent/JP2608227B2/ja not_active Expired - Lifetime
- 1992-06-02 TW TW081104335A patent/TW203007B/zh active
-
1993
- 1993-12-01 US US08/159,703 patent/US5480891A/en not_active Expired - Fee Related
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013058627A3 (ko) * | 2011-10-21 | 2013-07-04 | 가톨릭대학교 산학협력단 | 레바미피드를 유효성분으로 포함하는 비만의 예방 또는 치료용 조성물 |
| KR101395984B1 (ko) * | 2011-10-21 | 2014-05-16 | 가톨릭대학교 산학협력단 | 레바미피드를 유효성분으로 포함하는 비만의 예방 또는 치료용 조성물 |
Also Published As
| Publication number | Publication date |
|---|---|
| DE69207560T2 (de) | 1996-06-27 |
| JP2608227B2 (ja) | 1997-05-07 |
| CA2088582A1 (en) | 1992-12-08 |
| AU1783392A (en) | 1993-01-08 |
| WO1992021342A1 (en) | 1992-12-10 |
| TW203007B (enExample) | 1993-04-01 |
| EP0543018A1 (en) | 1993-05-26 |
| DE69207560D1 (de) | 1996-02-22 |
| DK0543018T3 (da) | 1996-02-05 |
| KR930701170A (ko) | 1993-06-11 |
| EP0543018A4 (en) | 1994-06-01 |
| EP0543018B1 (en) | 1996-01-10 |
| JPH05148143A (ja) | 1993-06-15 |
| US5480891A (en) | 1996-01-02 |
| AU645690B2 (en) | 1994-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19930203 |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19960509 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19930203 Comment text: Patent Application |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19980924 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 19981201 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 19981201 End annual number: 3 Start annual number: 1 |
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| PG1601 | Publication of registration | ||
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
Termination category: Default of registration fee Termination date: 20021011 |