CA2088582A1 - Anti-diabetes mellitus - Google Patents

Anti-diabetes mellitus

Info

Publication number
CA2088582A1
CA2088582A1 CA002088582A CA2088582A CA2088582A1 CA 2088582 A1 CA2088582 A1 CA 2088582A1 CA 002088582 A CA002088582 A CA 002088582A CA 2088582 A CA2088582 A CA 2088582A CA 2088582 A1 CA2088582 A1 CA 2088582A1
Authority
CA
Canada
Prior art keywords
diabetes mellitus
carbostyril
salt
bond
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002088582A
Other languages
English (en)
French (fr)
Inventor
Katsuya Yamasaki
Kazushi Sakurai
Kazue Akiyama
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2088582A1 publication Critical patent/CA2088582A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/22—Oxygen atoms attached in position 2 or 4
    • C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA002088582A 1991-06-07 1992-05-28 Anti-diabetes mellitus Abandoned CA2088582A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3/136465 1991-06-07
JP13646591 1991-06-07

Publications (1)

Publication Number Publication Date
CA2088582A1 true CA2088582A1 (en) 1992-12-08

Family

ID=15175749

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002088582A Abandoned CA2088582A1 (en) 1991-06-07 1992-05-28 Anti-diabetes mellitus

Country Status (9)

Country Link
US (1) US5480891A (enExample)
EP (1) EP0543018B1 (enExample)
JP (1) JP2608227B2 (enExample)
KR (1) KR0180248B1 (enExample)
CA (1) CA2088582A1 (enExample)
DE (1) DE69207560T2 (enExample)
DK (1) DK0543018T3 (enExample)
TW (1) TW203007B (enExample)
WO (1) WO1992021342A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW227558B (enExample) * 1992-05-14 1994-08-01 Otsuka Pharma Co Ltd
CA2150546C (en) * 1993-10-21 2004-11-09 Takahide Matsuda Agent for inhibiting production of interleukin-8
WO1995012579A1 (en) * 1993-11-05 1995-05-11 Otsuka Pharmaceutical Company, Limited Bismuth salt of carbostyril derivatives for the treatment of peptic ulcers
AR004214A1 (es) * 1995-10-12 1998-11-04 Otsuka Pharma Co Ltd Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas
IL121203A (en) * 1996-07-01 2001-04-30 Lilly Co Eli 1, 2, 3, 4-tetrahydroisoquinidines, process for their preparation and pharmaceutical compositions containing the same for treating hyperglycemia and hyperlipidemia
EP0925063A4 (en) 1996-07-01 2000-12-27 Lilly Co Eli Blood-glucose-lowering and lipid-lowering compounds
EP1212304A2 (en) 1999-08-27 2002-06-12 Eli Lilly And Company Hypoglycemic sulfonyl pyrazolones and pyrazolines
JP4394686B2 (ja) 2003-07-30 2010-01-06 大塚製薬株式会社 唾液分泌促進用医薬組成物およびその使用
TWI340650B (en) * 2004-01-21 2011-04-21 Otsuka Pharma Co Ltd Amine saly of carbostyril derivative
KR101395984B1 (ko) * 2011-10-21 2014-05-16 가톨릭대학교 산학협력단 레바미피드를 유효성분으로 포함하는 비만의 예방 또는 치료용 조성물

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE43079B1 (en) * 1975-03-20 1980-12-17 Ici Ltd Quinolone derivatives
JPS6026797B2 (ja) * 1976-07-12 1985-06-25 大塚製薬株式会社 新規なカルボスチリル誘導体
JPS609511B2 (ja) * 1976-07-16 1985-03-11 大塚製薬株式会社 ５−カルボスチリルメタノ−ル誘導体
JPS6037098B2 (ja) * 1978-01-13 1985-08-24 大塚製薬株式会社 ５―ホルミルカルボスチリル誘導体
JPS597168A (ja) * 1982-07-05 1984-01-14 Otsuka Pharmaceut Co Ltd カルボスチリル誘導体
US4578381A (en) * 1982-07-05 1986-03-25 Otsuka Pharmaceutical Co., Ltd. Carbostyril derivatives
JP2812998B2 (ja) * 1989-08-14 1998-10-22 大塚製薬 株式会社 胃炎治療剤
JP2820739B2 (ja) * 1989-10-28 1998-11-05 大塚製薬株式会社 カルボスチリル誘導体の製造法
JPH07112454A (ja) * 1993-10-19 1995-05-02 Sekisui Chem Co Ltd プラスチック成形品のボス構造

Also Published As

Publication number Publication date
DE69207560T2 (de) 1996-06-27
JP2608227B2 (ja) 1997-05-07
AU1783392A (en) 1993-01-08
WO1992021342A1 (en) 1992-12-10
TW203007B (enExample) 1993-04-01
EP0543018A1 (en) 1993-05-26
DE69207560D1 (de) 1996-02-22
DK0543018T3 (da) 1996-02-05
KR930701170A (ko) 1993-06-11
EP0543018A4 (en) 1994-06-01
KR0180248B1 (ko) 1999-03-20
EP0543018B1 (en) 1996-01-10
JPH05148143A (ja) 1993-06-15
US5480891A (en) 1996-01-02
AU645690B2 (en) 1994-01-20

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Legal Events

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