JPS6030654B2 - ヒトコロニ−刺激因子の製造方法 - Google Patents
ヒトコロニ−刺激因子の製造方法Info
- Publication number
- JPS6030654B2 JPS6030654B2 JP55185732A JP18573280A JPS6030654B2 JP S6030654 B2 JPS6030654 B2 JP S6030654B2 JP 55185732 A JP55185732 A JP 55185732A JP 18573280 A JP18573280 A JP 18573280A JP S6030654 B2 JPS6030654 B2 JP S6030654B2
- Authority
- JP
- Japan
- Prior art keywords
- cells
- human
- hcsf
- animal
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 102100022103 Histone-lysine N-methyltransferase 2A Human genes 0.000 description 1
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- 208000008839 Kidney Neoplasms Diseases 0.000 description 1
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- 229920002125 Sokalan® Polymers 0.000 description 1
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- 102000004142 Trypsin Human genes 0.000 description 1
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- 229940041181 antineoplastic drug Drugs 0.000 description 1
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- 239000000411 inducer Substances 0.000 description 1
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- 238000005406 washing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/10—Cells modified by introduction of foreign genetic material
- C12N5/12—Fused cells, e.g. hybridomas
- C12N5/16—Animal cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/948—Microorganisms using viruses or cell lines
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55185732A JPS6030654B2 (ja) | 1980-12-31 | 1980-12-31 | ヒトコロニ−刺激因子の製造方法 |
| GB8138591A GB2092159B (en) | 1980-12-31 | 1981-12-22 | Process for the production of human colony stimulating factor |
| IT49993/81A IT1148022B (it) | 1980-12-31 | 1981-12-23 | Procedimento per la produzione del fattore di stimolo della differenziazione cellulare nell'uomo |
| KR1019810005159A KR870001149B1 (ko) | 1980-12-31 | 1981-12-28 | 인체 콜로니 자극인자의 제조방법 |
| FR8124363A FR2497099A1 (fr) | 1980-12-31 | 1981-12-29 | Production de facteur leucopoietique humain |
| CH8352/81A CH649786A5 (fr) | 1980-12-31 | 1981-12-30 | Production de facteur leucopoietique humain. |
| US06/585,617 US4621050A (en) | 1980-12-31 | 1984-03-05 | Process for the production of human colony-stimulating factor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP55185732A JPS6030654B2 (ja) | 1980-12-31 | 1980-12-31 | ヒトコロニ−刺激因子の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57114525A JPS57114525A (en) | 1982-07-16 |
| JPS6030654B2 true JPS6030654B2 (ja) | 1985-07-17 |
Family
ID=16175883
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP55185732A Expired JPS6030654B2 (ja) | 1980-12-31 | 1980-12-31 | ヒトコロニ−刺激因子の製造方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4621050A (enExample) |
| JP (1) | JPS6030654B2 (enExample) |
| KR (1) | KR870001149B1 (enExample) |
| CH (1) | CH649786A5 (enExample) |
| FR (1) | FR2497099A1 (enExample) |
| GB (1) | GB2092159B (enExample) |
| IT (1) | IT1148022B (enExample) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6439855A (en) * | 1987-08-05 | 1989-02-10 | Nec Corp | Surface acoustic wave device |
| JPH02211748A (ja) * | 1989-02-10 | 1990-08-23 | Nec Eng Ltd | 直交変調回路 |
| JPH03241947A (ja) * | 1990-02-20 | 1991-10-29 | Murata Mfg Co Ltd | ４相位相変調器 |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS609795B2 (ja) * | 1980-12-11 | 1985-03-13 | 株式会社林原生物化学研究所 | ヒト上皮細胞成長因子の製造方法 |
| NZ228031A (en) * | 1984-07-06 | 1991-12-23 | Sandoz Ltd | Primate gm-csf and method of extraction |
| JPS61227526A (ja) * | 1984-07-25 | 1986-10-09 | Chugai Pharmaceut Co Ltd | 新規なコロニー刺激因子 |
| UA29377C2 (uk) * | 1984-09-19 | 2000-11-15 | Новартіс Аг | Спосіб отримання білка з активністю колонієстимулювального фактора гранулоцитів та макрофагів(gm-csf) приматів |
| US4968618A (en) * | 1984-11-16 | 1990-11-06 | University Of Florida | Composition and method for promoting growth of granulocytes |
| US6156300A (en) * | 1985-02-05 | 2000-12-05 | Chiron Corporation | Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof |
| US5573930A (en) | 1985-02-05 | 1996-11-12 | Cetus Oncology Corporation | DNA encoding various forms of colony stimulating factor-1 |
| EP0209601B1 (en) * | 1985-02-05 | 1993-12-15 | Cetus Oncology Corporation | Recombinant colony stimulating factor-1 |
| US6103224A (en) * | 1985-02-05 | 2000-08-15 | Chiron Corporation | N∇2 CSF-1 (short form) and carboxy truncated fragments thereof |
| US4847201A (en) * | 1985-02-05 | 1989-07-11 | Cetus Corporation | DNA encoding for CSF-1 and accompanying recombinant systems |
| EP0215126B1 (en) * | 1985-02-08 | 1991-07-31 | Chugai Seiyaku Kabushiki Kaisha | Human granulocyte colony stimulating factor |
| US5532341A (en) * | 1985-03-28 | 1996-07-02 | Sloan-Kettering Institute For Cancer Research | Human pluripotent hematopoietic colony stimulating factor |
| AU606585B2 (en) * | 1985-10-03 | 1991-02-14 | Biogen, Inc. | Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells |
| JPH0618778B2 (ja) * | 1985-10-04 | 1994-03-16 | 中外製薬株式会社 | 白血球減少症治療剤 |
| NZ218336A (en) * | 1985-12-09 | 1991-08-27 | Kirin Amgen Inc | Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf) |
| JPH0618780B2 (ja) * | 1986-01-22 | 1994-03-16 | 中外製薬株式会社 | 骨髄性白血病抑制剤 |
| JPH0618779B2 (ja) * | 1986-01-22 | 1994-03-16 | 中外製薬株式会社 | 造血機能回復促進剤 |
| ZA874410B (en) * | 1986-06-24 | 1988-04-27 | Merrell Dow Pharma | Fusion products |
| US5162111A (en) * | 1986-07-30 | 1992-11-10 | Grabstein Kenneth H | Treatment of bacterial diseases with granulocyte-macrophage colony stimulating factor |
| JPH0618781B2 (ja) * | 1986-10-18 | 1994-03-16 | 中外製薬株式会社 | 感染症治療剤 |
| JPS63245667A (ja) * | 1987-03-31 | 1988-10-12 | Ube Ind Ltd | 肥満細胞成長活性を有するヒトｉｌ−３産生ヒト細胞および肥満細胞成長活性を有するヒトｉｌ−３の製造方法 |
| US7094400B1 (en) * | 1987-05-01 | 2006-08-22 | Shire Human Genetic Therapies, Inc. | Transkaryotic implantation |
| US4847325A (en) * | 1988-01-20 | 1989-07-11 | Cetus Corporation | Conjugation of polymer to colony stimulating factor-1 |
| US5148267A (en) * | 1989-09-08 | 1992-09-15 | Hewlett-Packard Company | Double heterostructure step recovery diode with internal drift field |
| CA2044468C (en) * | 1990-11-21 | 2006-08-22 | Richard A. Nash | Canine granulocyte macrophage colony stimulating factor |
| US6653134B2 (en) * | 1995-03-28 | 2003-11-25 | Cp Hahnemann University | Isolated stromal cells for use in the treatment of diseases of the central nervous system |
| US6974571B2 (en) * | 1995-03-28 | 2005-12-13 | Thomas Jefferson University | Isolated stromal cells and methods of using the same |
| US6136599A (en) * | 1998-12-10 | 2000-10-24 | Bayer Corporation | Human hybrid host cell for mammalian gene expression |
| US20030044398A1 (en) * | 2001-03-20 | 2003-03-06 | Robl James M. | Methods for producing antibodies in mammals |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2016015B (en) * | 1978-01-22 | 1982-05-06 | Hayashibara Co | Method of preparing interferon and preparations containing interferon |
| US4242460A (en) * | 1978-12-26 | 1980-12-30 | Chick William L | Cell culture device |
| JPS5598118A (en) * | 1979-01-18 | 1980-07-25 | Hayashibara Takeshi | Preparation of type-2 interferon and drug containing the same |
| US4342828A (en) * | 1979-07-20 | 1982-08-03 | Morinaga Milk Industry Co., Ltd. | Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells |
| US4328207A (en) * | 1979-12-27 | 1982-05-04 | Ken Hayashibara | Process for preparing mouse interferon |
| JPS586475B2 (ja) * | 1980-08-23 | 1983-02-04 | 株式会社 林原生物化学研究所 | ヒト絨毛性性腺刺激ホルモンの製造方法 |
| JPS6045849B2 (ja) * | 1980-08-25 | 1985-10-12 | 林原 健 | ヒトエリトロポエチンの製造方法 |
| JPS5743696A (en) * | 1980-08-27 | 1982-03-11 | Hayashibara Biochem Lab Inc | Preparation of human luteinizing hormone |
| JPS585671B2 (ja) * | 1980-08-27 | 1983-02-01 | 株式会社 林原生物化学研究所 | ヒト卵胞刺激ホルモンの製造方法 |
-
1980
- 1980-12-31 JP JP55185732A patent/JPS6030654B2/ja not_active Expired
-
1981
- 1981-12-22 GB GB8138591A patent/GB2092159B/en not_active Expired
- 1981-12-23 IT IT49993/81A patent/IT1148022B/it active
- 1981-12-28 KR KR1019810005159A patent/KR870001149B1/ko not_active Expired
- 1981-12-29 FR FR8124363A patent/FR2497099A1/fr active Granted
- 1981-12-30 CH CH8352/81A patent/CH649786A5/fr not_active IP Right Cessation
-
1984
- 1984-03-05 US US06/585,617 patent/US4621050A/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6439855A (en) * | 1987-08-05 | 1989-02-10 | Nec Corp | Surface acoustic wave device |
| JPH02211748A (ja) * | 1989-02-10 | 1990-08-23 | Nec Eng Ltd | 直交変調回路 |
| JPH03241947A (ja) * | 1990-02-20 | 1991-10-29 | Murata Mfg Co Ltd | ４相位相変調器 |
Also Published As
| Publication number | Publication date |
|---|---|
| GB2092159A (en) | 1982-08-11 |
| IT8149993A0 (it) | 1981-12-23 |
| KR870001149B1 (ko) | 1987-06-11 |
| GB2092159B (en) | 1984-07-18 |
| US4621050A (en) | 1986-11-04 |
| IT1148022B (it) | 1986-11-26 |
| CH649786A5 (fr) | 1985-06-14 |
| FR2497099A1 (fr) | 1982-07-02 |
| KR830007826A (ko) | 1983-11-07 |
| JPS57114525A (en) | 1982-07-16 |
| FR2497099B1 (enExample) | 1984-11-09 |
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