KR870001149B1 - 인체 콜로니 자극인자의 제조방법 - Google Patents

인체 콜로니 자극인자의 제조방법 Download PDF

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Publication number
KR870001149B1
KR870001149B1 KR1019810005159A KR810005159A KR870001149B1 KR 870001149 B1 KR870001149 B1 KR 870001149B1 KR 1019810005159 A KR1019810005159 A KR 1019810005159A KR 810005159 A KR810005159 A KR 810005159A KR 870001149 B1 KR870001149 B1 KR 870001149B1
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KR
South Korea
Prior art keywords
human
cells
hcsf
lymphoblasts
colony stimulating
Prior art date
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Expired
Application number
KR1019810005159A
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English (en)
Korean (ko)
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KR830007826A (ko
Inventor
가나메 스기모도
Original Assignee
가부시기 가이샤 하이시바라 세이부쓰 가가꾸 겡규우죠
하야시바라겡
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Application filed by 가부시기 가이샤 하이시바라 세이부쓰 가가꾸 겡규우죠, 하야시바라겡 filed Critical 가부시기 가이샤 하이시바라 세이부쓰 가가꾸 겡규우죠
Publication of KR830007826A publication Critical patent/KR830007826A/ko
Application granted granted Critical
Publication of KR870001149B1 publication Critical patent/KR870001149B1/ko
Expired legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/948—Microorganisms using viruses or cell lines

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019810005159A 1980-12-31 1981-12-28 인체 콜로니 자극인자의 제조방법 Expired KR870001149B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP55185732A JPS6030654B2 (ja) 1980-12-31 1980-12-31 ヒトコロニ−刺激因子の製造方法
JP80-185732 1980-12-31
JP185732 1980-12-31

Publications (2)

Publication Number Publication Date
KR830007826A KR830007826A (ko) 1983-11-07
KR870001149B1 true KR870001149B1 (ko) 1987-06-11

Family

ID=16175883

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810005159A Expired KR870001149B1 (ko) 1980-12-31 1981-12-28 인체 콜로니 자극인자의 제조방법

Country Status (7)

Country Link
US (1) US4621050A (enExample)
JP (1) JPS6030654B2 (enExample)
KR (1) KR870001149B1 (enExample)
CH (1) CH649786A5 (enExample)
FR (1) FR2497099A1 (enExample)
GB (1) GB2092159B (enExample)
IT (1) IT1148022B (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS609795B2 (ja) * 1980-12-11 1985-03-13 株式会社林原生物化学研究所 ヒト上皮細胞成長因子の製造方法
NZ228031A (en) * 1984-07-06 1991-12-23 Sandoz Ltd Primate gm-csf and method of extraction
JPS61227526A (ja) * 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
UA29377C2 (uk) * 1984-09-19 2000-11-15 Новартіс Аг Спосіб отримання білка з активністю колонієстимулювального фактора гранулоцитів та макрофагів(gm-csf) приматів
US4968618A (en) * 1984-11-16 1990-11-06 University Of Florida Composition and method for promoting growth of granulocytes
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5573930A (en) 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
EP0209601B1 (en) * 1985-02-05 1993-12-15 Cetus Oncology Corporation Recombinant colony stimulating factor-1
US6103224A (en) * 1985-02-05 2000-08-15 Chiron Corporation N∇2 CSF-1 (short form) and carboxy truncated fragments thereof
US4847201A (en) * 1985-02-05 1989-07-11 Cetus Corporation DNA encoding for CSF-1 and accompanying recombinant systems
EP0215126B1 (en) * 1985-02-08 1991-07-31 Chugai Seiyaku Kabushiki Kaisha Human granulocyte colony stimulating factor
US5532341A (en) * 1985-03-28 1996-07-02 Sloan-Kettering Institute For Cancer Research Human pluripotent hematopoietic colony stimulating factor
AU606585B2 (en) * 1985-10-03 1991-02-14 Biogen, Inc. Human granulocyte-macrophage colony stimulating factor-like polypeptides and processes for producing them in high yields in microbial cells
JPH0618778B2 (ja) * 1985-10-04 1994-03-16 中外製薬株式会社 白血球減少症治療剤
NZ218336A (en) * 1985-12-09 1991-08-27 Kirin Amgen Inc Monoclonal antibodies to human pluripotent granulocyte colony stimulating factor (hpg-csf)
JPH0618780B2 (ja) * 1986-01-22 1994-03-16 中外製薬株式会社 骨髄性白血病抑制剤
JPH0618779B2 (ja) * 1986-01-22 1994-03-16 中外製薬株式会社 造血機能回復促進剤
ZA874410B (en) * 1986-06-24 1988-04-27 Merrell Dow Pharma Fusion products
US5162111A (en) * 1986-07-30 1992-11-10 Grabstein Kenneth H Treatment of bacterial diseases with granulocyte-macrophage colony stimulating factor
JPH0618781B2 (ja) * 1986-10-18 1994-03-16 中外製薬株式会社 感染症治療剤
JPS63245667A (ja) * 1987-03-31 1988-10-12 Ube Ind Ltd 肥満細胞成長活性を有するヒトｉｌ−３産生ヒト細胞および肥満細胞成長活性を有するヒトｉｌ−３の製造方法
US7094400B1 (en) * 1987-05-01 2006-08-22 Shire Human Genetic Therapies, Inc. Transkaryotic implantation
JPS6439855A (en) * 1987-08-05 1989-02-10 Nec Corp Surface acoustic wave device
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
JPH02211748A (ja) * 1989-02-10 1990-08-23 Nec Eng Ltd 直交変調回路
US5148267A (en) * 1989-09-08 1992-09-15 Hewlett-Packard Company Double heterostructure step recovery diode with internal drift field
JPH03241947A (ja) * 1990-02-20 1991-10-29 Murata Mfg Co Ltd ４相位相変調器
CA2044468C (en) * 1990-11-21 2006-08-22 Richard A. Nash Canine granulocyte macrophage colony stimulating factor
US6653134B2 (en) * 1995-03-28 2003-11-25 Cp Hahnemann University Isolated stromal cells for use in the treatment of diseases of the central nervous system
US6974571B2 (en) * 1995-03-28 2005-12-13 Thomas Jefferson University Isolated stromal cells and methods of using the same
US6136599A (en) * 1998-12-10 2000-10-24 Bayer Corporation Human hybrid host cell for mammalian gene expression
US20030044398A1 (en) * 2001-03-20 2003-03-06 Robl James M. Methods for producing antibodies in mammals

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2016015B (en) * 1978-01-22 1982-05-06 Hayashibara Co Method of preparing interferon and preparations containing interferon
US4242460A (en) * 1978-12-26 1980-12-30 Chick William L Cell culture device
JPS5598118A (en) * 1979-01-18 1980-07-25 Hayashibara Takeshi Preparation of type-2 interferon and drug containing the same
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
US4328207A (en) * 1979-12-27 1982-05-04 Ken Hayashibara Process for preparing mouse interferon
JPS586475B2 (ja) * 1980-08-23 1983-02-04 株式会社 林原生物化学研究所 ヒト絨毛性性腺刺激ホルモンの製造方法
JPS6045849B2 (ja) * 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
JPS5743696A (en) * 1980-08-27 1982-03-11 Hayashibara Biochem Lab Inc Preparation of human luteinizing hormone
JPS585671B2 (ja) * 1980-08-27 1983-02-01 株式会社 林原生物化学研究所 ヒト卵胞刺激ホルモンの製造方法

Also Published As

Publication number Publication date
GB2092159A (en) 1982-08-11
IT8149993A0 (it) 1981-12-23
GB2092159B (en) 1984-07-18
US4621050A (en) 1986-11-04
IT1148022B (it) 1986-11-26
CH649786A5 (fr) 1985-06-14
FR2497099A1 (fr) 1982-07-02
KR830007826A (ko) 1983-11-07
JPS57114525A (en) 1982-07-16
JPS6030654B2 (ja) 1985-07-17
FR2497099B1 (enExample) 1984-11-09

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